MS4A6A/Ms4a6d deficiency disrupts neuroprotective microglia functions and promotes inflammation in Alzheimer's disease model.

Background: Alzheimer's disease (AD) is the most common type of dementia. Genetic polymorphisms are associated with altered risks of AD onset, pointing to biological processes and potential targets for interventions. Consistent with the important roles of microglia in AD development, genetic mutations of several genes expressed on microglia have been identified as risks for AD.

The influence of physical activity on emotional management ability in college students: a chain mediating role of psychological resilience and health literacy.

Objective: This study aimed to investigate the impact of physical activity (PA) on emotional management ability (EMA) in college students and to analyze the chain mediating roles of psychological resilience (PR) and health literacy (HL) in the relationship between PA and EMA.

Methods: Demographic information was collected using a stratified, cluster, and multi-stage sampling method. Data on PA, PR, HL, and EMA among college students were collected using an online questionnaire.

The effect of physical exercise on sleep quality in university students: chain mediation of health literacy and life satisfaction.

Objective: The present study was designed to explore the relationship between physical exercise and sleep quality. Specifically, it investigates the extent to which this relationship is mediated by a sequential process involving health literacy and life satisfaction.

Methods: Data on physical exercise, sleep quality, health literacy, and life satisfaction were collected from a sample of 12,646 college students (study participants) using a questionnaire.

The impact of physical exercise on university students' life satisfaction: The chain mediation effects of general self-efficacy and health literacy.

Objective: This study aims to explore the impact of physical exercise on university students' life satisfaction and analyses the chain mediation effect of general self-efficacy and health literacy, providing empirical reference and theoretical foundation for the comprehensive enhancement and optimization of students' mental health.

Method: Based on data from the "China University Student Physical Activity and Health Tracking Survey" (CPAHLS-CS) 2024, the measurement scales used included the Physical Activity Rating Scale (PARS-3), the Satisfaction with Life Scale (SWLS), the General Self-Efficacy Scale (GSES), and the 9-item Short Form Health Literacy Scale (HLS-SF9). A total of 4575 valid samples were analyzed.

The impact of physical activity on self-emotion management among university students in Western China: the mediating roles of self-rated health and life satisfaction.

Objective: This study aims to investigate the impact of Physical Activity on Self-Emotional Management among university students and to verify the mediating roles of Self-Rated Health and Life Satisfaction.

Methods: A stratified cluster sampling method was used to enroll 10,300 university students from Western China. Questionnaires were used to collect data, which included demographic and sociological information, the Physical Activity Scale (for measuring Physical Activity), the Emotional Intelligence Scale (for measuring Self-Emotional Management), the Short-Form Health Survey (for measuring Self-Rated Health), and the Satisfaction with Life Scale (for measuring Life Satisfaction).

From Orthorhombic CuGeS to Cubic CuHgGeS: Second-Harmonic Generation and Photocurrent Responses.

A new noncentrosymmetric sulfide, CuHgGeS (CHGS), has been successfully synthesized via a heterovalent substitution strategy based on argyrodite-type CuGeS (CGS). Benefiting from the substitution of Cu with Hg cation, the structure changes from orthorhombic 2 to cubic 23. CHGS exhibits obvious nonlinear optical (NLO) activity, while CGS not.

Status and epidemiological characteristics of depression and anxiety among Chinese university students in 2023.

Objective: This study aims to understand the status of depression and anxiety among Chinese university students through epidemiological investigation of a large sample size and provide a foundation for identifying individuals at risk of psychological crisis and developing targeted intervention strategies.

Methods: Survey participants were selected using a multi-stage sampling approach, which incorporated elements of stratification and cluster sampling. The main participants consisted of 49,717 university students from 106 Chinese universities.

Cross sectional associations of physical activity and sleep with mental health among Chinese university students.

Objective: This study aimed to examine the levels of physical activity (PA), sleep, and mental health (MH), specifically depression, anxiety, and stress, among Chinese university students. It also aimed to analyze the influencing factors of MH, providing a theoretical foundation for developing intervention programs to improve college students' mental health.

Methods: A stratified, clustered, and phased sampling method was employed.

Effect of physical exercise on negative emotions in Chinese university students: The mediating effect of self-efficacy.

Objective: This study investigates the impact of physical activity on negative emotions among university students and examines the mediating influence of self-efficacy, aiming to furnish empirical insights and a theoretical framework to enhance and optimize the mental health of this population comprehensively.

Methods: Using the cluster random sampling method, 5341 university students were selected from three universities. The questionnaire included demographic information about university students, physical exercise behaviors, expressions of negative emotions such as depression and anxiety, and self-efficacy in physical exercise.

An Observational Study: Association Between Atopic Dermatitis and Bacterial Colony of the Skin Based on 16S rRNA Gene Sequencing.

Aim: Atopic dermatitis (AD) often accompanies skin infections, and bacterial skin infections often cause persistent and worsening symptoms. In this study, we explored the key changes in the microbiota of AD patients, as well as the effects of different ages and the severity of rash on changes in the microbiota.

Patients And Methods: A total of 95 AD patients and 77 healthy volunteers were recruited.

Controlled Synthesis, Chiral Assembly, and Circularly Polarized Luminescence of Poly(Phenyl Isocyanide)-Block-Polyfluorene Copolymers.

In this work, π-conjugated block copolymers consisting of poly(phenyl isocyanide) (PPI) and polyfluorene (PF) segments are facilely prepared by one-pot sequential polymerization of phenyl isocyanide (monomer 1) and 7-bromo-9,9-dioctylfluorene-2-boronic acid pinacol ester (monomer 2). The Pd(II)-terminated PPI is first prepared via polymerizing monomer 1 catalyzed with phenyl alkyne-Pd(II) complex and then utilized to initiate the controlled Suzuki cross-coupling polymerization of monomer 2, yielding various PPI-b-PF copolymers possessing controlled molar mass and narrow dispersity. Owing to the helical conformation of PPI segment and π-conjugated structure of PF segment, PPI-b-PF copolymers present distinctive optical property and fascinating chiral self-assembly behavior.

Mixed Rare-Earth Chalcogenide Borate EuREMgSBO (RE = Sm, Gd) Featuring a 3D {[BO]} Framework Connected by [BO(O)] and [BO(O)] Clusters.

Rare-earth (RE) chalcogenide borates are very rarely discovered in view of the difficulties in synthesis though they have demonstrated attractive physical performances. Here, the first mixed RE chalcogenide borates EuSmMgSBO () and EuGdMgSBO () are synthesized by combining RE, sulfur, and borate ions into one structure. They crystallize in the centrosymmetric hexagonal space group 6/, and their 3D honeycomb-like {[BO]} open frameworks are built by [BO(O)] and [BO(O)] polyanionic clusters and consolidated by Mg ions; both of which are formed by BO tetrahedra and BO planar triangles.

Chinese college students COVID-19 phobia and negative moods: Moderating effects of physical exercise behavior.

Objective: We investigated the effects of COVID-19 fear on negative moods among college students, and assessed the efficacy of physical exercise behavior as a moderator variable.

Methods: This was a cross-sectional study. Students from three colleges and universities in Shangqiu City, Henan Province and Yangzhou City, Jiangsu Province were enrolled in this study, which was performed during the COVID-19 pandemic using an online questionnaire.

Chinese College Students' Physical-Exercise Behavior, Negative Emotions, and Their Correlation during the COVID-19 Outbreak.

Background: In the period of the COVID-19 pandemic, the level of college students' physical exercise, the detection rate of negative emotions, and their correlation should attract extensive attention. Therefore, this study aimed to explore the correlation between college students' physical exercise and negative emotions.

Methods: Data were collected via a web-based cross-sectional survey.

Physical Fitness, Exercise Behaviors, and Sense of Self-Efficacy Among College Students: A Descriptive Correlational Study.

Background: Self-efficacy is an important component of the mental well-being of college students. This study aimed to evaluate the development and the correlation between physical fitness (PF), exercise behavior, and self-efficacy in college students. To examine whether PF in individual college students can predict self-efficacy, and whether exercise behavior mediates this relationship.

NaGaSe: An Infrared Nonlinear Optical Material with Balanced Performance Contributed by Complex {[GaSe]} Anionic Network.

Second-order nonlinear optical (NLO) materials are extensively applied in laser-related techniques. For developing IR NLO materials, chalcogenides are the main candidates. Here, NaGaSe was explored as inspired by its unique anionic structure.

[CiteSpace knowledge map analysis of research progress on Tripterygium wilfordii toxicity].

This study systematically searched CNKI and Web of Science(WoS) for the research papers on the toxicity of Tripterygium wilfordii included from database inception to August 31, 2021, and visually displayed the authors, research institutions, keywords, and other contents using bibliometrics and CiteSpace 5.8.3.

KEuInBS: a novel type of thioborate featuring BS cluster and unique InS 12-membered ring.

Both borates and sulfides are important inorganic multifunctional materials. Encouraged by this background, thioborates attract considerable interest. However, their investigations are highly hindered by the scarcity of the available ones and the synthetic difficulty of the new ones.

Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank.

Background: In gut microbiome studies, the cultured gut microbial resource plays essential roles, such as helping to unravel gut microbial functions and host-microbe interactions. Although several major studies have been performed to elucidate the cultured human gut microbiota, up to 70% of the Unified Human Gastrointestinal Genome species have not been cultured to date. Large-scale gut microbial isolation and identification as well as availability to the public are imperative for gut microbial studies and further characterizing human gut microbial functions.