[Motor imagery classification based on dynamic multi-scale convolution and multi-head temporal attention].

Convolutional neural networks (CNNs) are renowned for their excellent representation learning capabilities and have become a mainstream model for motor imagery based electroencephalogram (MI-EEG) signal classification. However, MI-EEG exhibits strong inter-individual variability, which may lead to a decline in classification performance. To address this issue, this paper proposes a classification model based on dynamic multi-scale CNN and multi-head temporal attention (DMSCMHTA).

N-Doped Porous Graphite-Like Carbon Armored with Dense Amorphous Shell Through a Trojan Horse Strategy for High Performance Potassium-Ion Battery Anode.

N-doped porous carbon materials are promising potassium-ion battery anodes for overcoming the depressing rate performance and poor cycling stability issues associated with the oversized radius of K-ion. However, the relatively low initial coulombic efficiency (ICE) as a result of porous structure and doped heteroatoms may limit the future application of potassium-ion batteries. Herein, a novel N-doped porous graphite-like carbon armored with dense amorphous shell is synthesized through a Trojan horse strategy by etching and doping the carbon matrix from inside out using oxidized coal tar pitch coated CN as precursor.

Molecular and Drug Resistance Characteristics of Carried by Pediatric Patients with Adenoid Hypertrophy.

Purpose: The adenoid microbiota plays a key role in adenoid hypertrophy (AH). This study explored the molecular epidemiology and antimicrobial resistance of () strains in pediatric AH patients.

Methods: Retrospective analysis of pediatric AH patients undergoing endoscopic adenoidectomy.

Robust Mesoporous SiO-Coated TiO Colloidal Nanocrystal with Enhanced Adsorption, Stability, and Adhesion for Photocatalytic Antibacterial and Benzene Removal.

The utility of nanostructured TiO in the degradation of organic compounds and the disinfection of pathogenic microorganisms represents an important endeavor in photocatalysis. However, the low photocatalytic efficiency of TiO remains challenging. Herein, we report a robust photocatalytic route to benzene removal rendered by enhancing its adsorption capacity via rationally designed mesoporous SiO-coated TiO colloids.

Neurotoxic impacts of neonicotinoid pesticide residues in Chinese honey on Apis mellifera L.

Background: The threat to bees of neonicotinoid pesticides (NEOs) has raised concern. However, data on the disruption of the bee nervous system following long-term low-dose exposure are lacking. In this study, six NEOs were quantified in 31 honey samples from China, and their behavioral effects on bees were evaluated.

MicroRNA Signatures in Dental Pulp Stem Cells Following Nicotine Exposure.

Nicotine is the most well-studied toxic substance in cigarette smoke and e-cigarette vape. However, smoke and vape are composed of other components that have a negative impact on health. The objective of this study is to investigate whether nicotine has a distinctive impact on molecular mechanisms in stem cells.

Lysozyme "self-sacrificing" quenching reactive oxygen species blocks egg white protein oxidation and dilution degradation.

This study explored the mechanism by which lysozyme (LYZ) actively quenched reactive oxygen species (ROS) to inhibit egg white protein (EWP) oxidation. By depleting/replenishing LYZ in EWP systems, we evaluated EWP stability, oxidation degree, microstructure, and conformational changes during storage. Results showed that compared to the control group with significantly reduced LYZ activity, 0.

A tale of two cities: Examining the impact of COVID-19 lockdown on young children's emotional distress.

Based on 814 3- to 4-year-olds (408 girls; Han Chinese: 97.5%) from Wuhan and Zhengzhou, two cities in China affected by COVID-19 to varying degrees, this study examined the impact of COVID-19 and lockdowns on children's emotional distress and its underlying family-level mechanisms. Children living in a city with "high-load" coronavirus and lockdown (Wuhan) exhibited more symptoms of anxiety/withdrawal, fear, and acting out than their counterparts living in a city with "low loads" (Zhengzhou; s = .

Optimizing Time-Sensitive Traffic Scheduling in Low-Earth-Orbit Satellite Networks.

In contrast to terrestrial networks, the rapid movement of low-earth-orbit (LEO) satellites causes frequent changes in the topology of intersatellite links (ISLs), resulting in dynamic shifts in transmission paths and fluctuations in multi-hop latency. Moreover, limited onboard resources such as buffer capacity and bandwidth competition contribute to the instability of these links. As a result, providing reliable quality of service (QoS) for time-sensitive flows (TSFs) in LEO satellite networks becomes a challenging task.

Prescription Medication Expenditures for Patients With Diabetes in the United States: 2012-2021.

Glucose-lowering medication expenditures per user by different payers among patients with diabetes.

Leisure activity participation, health status, and subjective well-being of adult women: a cross-sectional study from a life cycle perspective in China.

Objective: Based on life cycle theory, this study aims to explore the changes in leisure activity participation, health status, and subjective well-being among women at different life stages, and to investigate the underlying mechanisms. Additionally, the study examines the moderating effects of demographic characteristics.

Methods: This study used data from the China General Social Survey (CGSS) and employed a cross-sectional research design to compare data from women in early adulthood, early maturity, and late maturity.

Expression of LINE-1 elements is required for preimplantation development and totipotency.

Transposable elements, long considered genomic intruders, have been found to play significant and intriguing roles during early embryonic development based on the paradigm shift that has undergone in recent years. Long interspersed element-1 (LINE-1) is the predominant class of retrotransposons with autonomous retrotransposition capabilities in mammals and has emerged as a crucial element of preimplantation development. In this review, we elucidate the expression dynamics of key transposable elements throughout preimplantation development and their contribution to the regulation of developmental progression and totipotency.

Low-Temperature Carbonization Synthesis of Sulfonic Group Dominated N/S Co-Doped Carbon for High-Performance Potassium-Ion Batteries.

The nitrogen/sulfur (N/S) co-doping strategy has gained significant attention in the development of carbon-based anodes for potassium-ion batteries (PIBs) due to its capapcity to enhance specific capacity and accelerate reaction kinetics. Yet, the C─S bond-driven conversion reaction would inevitably induce critical challenges, including poor stability and high charging voltage, thereby severely impeding the commercialization of N/S co-doped carbon anodes. Herein, a novel sulfonic group dominated N/S co-doped carbon (NSAC-600) is synthesized via a facile low-temperature carbonization strategy with coal tar pitch as a precursor.

Cost-related non-adherence in US adults with heart failure: a repeated cross-sectional analysis of the medical expenditure panel survey, 2012 to 2021.

Objectives: To investigate the prevalence and potential determinants of cost-related non-adherence (CRNA) in US adults with heart failure (HF).

Design: A serial cross-sectional analysis using nationally representative data from 2012 to 2021 of the US Medical Expenditure Panel Survey.

Setting: Population-based.

Detection of novel organophosphorus flame retardants and plasticizers in children urines: Associations with oxidative stress damage and thyroid nodule risk.

Organophosphorus flame retardants and plasticizers (OPFRs) are prevalent and raise health concerns due to their endocrine-disrupting properties. Clinically detectable thyroid nodules are less common in children than in adults but pose a higher malignancy risk. The effects of OPFRs on children's thyroid nodules and their relation to oxidative stress remain unknown.

Chronic Exposure to Fluxapyroxad Exacerbated Susceptibility to Colitis in Mice via a Gut Microbiota-Indole Derivatives-Th17/Treg Cell Balance Axis.

Fluxapyroxad is the most commonly used succinate dehydrogenase inhibitor fungicide. This work investigated its adverse effects on colitis susceptibility and explored the underlying mechanisms based on a mouse model. After 13 weeks of exposure at the acceptable daily intake (ADI) level, fluxapyroxad exacerbated the susceptibility to colitis, impaired the intestinal barrier, and elevated proinflammatory cytokines and chemokines of the colon in mice.

Multi-omics profiling of acute pneumonia unmasks conventional NK cell depletion and stage-specific therapeutic targets.

(PA) is a key pathogen in hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), challenging clinical medicine. This study aims to elucidate the characteristics of the host's innate immune response following inhalational PA infection. We developed a mouse model by aerosolized intratracheal inoculation with PA and conducted a comprehensive analysis at the protein, cellular, and gene expression levels.

ROS burst prolongs transcriptional condensation to slow shoot apical meristem maturation and achieve heat-stress resilience in tomato.

The transition of the shoot apical meristem (SAM) from vegetative growth to flowering, a key step of angiosperm reproductive success, is highly vulnerable to heat stress. Overproduction of reactive oxygen species (ROS) is a hallmark of such environmental stresses, but how SAM exploits the extra ROS to achieve heat-stress resilience is largely unknown. Here, we report that tomato plants respond to heat-induced ROS burst by slowing down SAM maturation and lengthening the vegetative state to achieve heat resilience.

Prognostic implications of tumor volume reduction during radiotherapy in locally advanced cervical cancer: a risk-stratified analysis.

Background: This study aimed to identify key risk factors in locally advanced cervical cancer (LACC) patients receiving radical radiotherapy and to evaluate the prognostic significance of MRI-determined tumor volume regression (TVR) among varying risk groups.

Methods: We retrospectively analyzed a cohort of 176 cervical cancer patients (stages IIA-IVA) treated with intensity-modulated radiotherapy from January 2012 to December 2020. Three-dimensional MRI scans were utilized to measure TVR and lymph node volume regression (NVR).

Endogenous Near-Infrared Chemiluminescence: Imaging-Guided Non-Invasive Thrombolysis and Anti-Inflammation Based on a Heteronuclear Transition Metal Complex.

Conventional therapy to treat thrombi (blood clots) has significant limitations: i) inflammation; ii) bleeding side effects; iii) re-embolisation, and iv) in situ thrombi that are not visible. Here it is reported that Cu2Ir nanoparticles (NPs) with a Cu-coordinated tetraphenylporphyrin (TPP) core and cyclometalated Ir(C^N)(N^N) substituents integrate long-lived near-infrared (NIR) chemiluminescence (CL) imaging, photothermal therapy (PTT) and photodynamic therapy (PDT) for thrombolysis, with antioxidant and anti-inflammatory properties. Based on density functional theory calculations the chemiluminescent reaction site between TPP and peroxynitrite (ONOO) is confirmed for the first time.

An electrochromism-equipped enzymatic biofuel cell system combined with hollow microneedle array for self-powered glucose sensing in interstitial fluid.

A disposable, self-powered enzymatic biofuel cell (BFC) sensor integrated with a hollow microneedle array (HMNA) for glucose monitoring in interstitial fluid (ISF) is reported. The HMNA enables painless and minimally invasive ISF extraction. The BFC uses dehydrogenase (GDH) in conjunction with NAD, diaphorase (DI), and vitamin K (VK) serving as electron transfer mediators as the anode catalyst and Prussian blue (PB) as the electrochromic cathode.

Polo-like kinase2 regulates renal tubulointerstitial fibrosis via notch signaling pathway in diabetic kidney disease.

Renal tubulointerstitial fibrosis is considered as an important pathological feature of diabetic kidney disease (DKD). However, the underlying mechanism remains unclear. Polo-like kinase2 (PLK2) is a known player in the regulation of organ fibrosis.

Entry Into Boarding Preschool Is Associated With Increased Stress and School Refusal.

In western China, many socioeconomically disadvantaged rural children remain at preschools for extremely long hours: they start to receive boarding services as young as 3 years old and remain at preschools for 4 to 5 consecutive days weekly. Although the quality of childcare is generally poor in these preschools, extremely long school hours and prolonged separation from primary caregivers may induce additional stress and lead to school maladjustment among boarding preschoolers. This study examines the impact of boarding experience on preschool beginners' social adjustment and stress responses, as indicated by their saliva alpha-amylase (sAA) and cortisol.

Associations of serial negative income shock and all-cause mortality: a longitudinal study in China.

Introduction: With a precarious economic outlook and increasing income volatility in current times, understanding the association between negative income shock and health is crucial. However, few studies have examined such associations in developing countries. Using data from China, this study aimed to examine associations of both serial absolute income drops and relative income trajectory and mortality.

JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis.

Background: The Jumonji domain-containing protein 6 (JMJD6), a histone arginine demethylase, is known to have a multifaceted and significant role on cancer progression. However, the specific function and mechanism of JMJD6 in non-small cell lung cancer (NSCLC) have yet to be fully elucidated.

Methods: The elevated expression of JMJD6 in lung cancer tissues was confirmed through a combination of bioinformatics and immunohistochemical analysis.