The Liquid Crystal Monomer 3cH2B Affects the Visual System via Neural-Cell-Specific Retinoic Acid Disruption in the Optic Tectum.

As a newly recognized type of emerging contaminant, liquid crystal monomers (LCMs) are widely distributed in the environment and human consumptions and their effects on visual systems and the underlying mechanisms are yet to be elucidated. Therefore, this study investigated the visual-neuro influence of 3cH2B (a frequently detected LCM) under environmentally relevant concentrations in zebrafish. The findings revealed that 40 μg/L 3cH2B induced visual behaviors after 40 days of exposure, which was accompanied by decreased retinoic acid (RA) levels and retinal structural deformation in the eyes.

Modulation of Wnt/β-Catenin Signaling by STAT3 Inhibition Restores Myogenic Capacity in Sarcopenia.

Background: Sarcopenia is a progressive disorder characterized by loss of skeletal muscle mass, strength, and function. Although STAT3 is known to regulate myogenic differentiation, its role in sarcopenia remains unclear.

Methods: STAT3 expression was assessed in skeletal muscle samples from sarcopenia patients and nonsarcopenic controls, as well as aged SAMP8 mice.

Elastic Properties of BiOCl and BiOCl Freestanding Circular Membranes.

Bismuth oxychlorides are emerging two-dimensional wide-bandgap semiconductors with exceptional potential for advanced photoelectric applications. Elastic strain engineering is a promising strategy to enhance their photoelectric performances. However, fundamental elastic properties of bismuth oxychlorides are largely unknown.

Characteristics of Neonicotinoids in Colostrum from Shanghai, China (2007-2019): Concentration Levels, Temporal Trends, and Potential Health Risk.

Neonicotinoids (NEOs) are widely used neuroactive insecticides with several adverse effects on human health. This study examined 186 colostrum samples collected at three time points between 2007 and 2019 from Shanghai, China to investigate the distribution and temporal variations of NEOs. The median total concentration (ΣNEOs) was 136 ng/L, with the imidacloprid equivalent concentration (IMIeq) of 249 ng/L.

Identification of the Cold-Related Genes COLD11 and OsCTS11 via BSA-seq and Fine Mapping at the Rice Seedling Stage.

Cold stress has a significantly negative effect on the growth, development, and yield of rice. However, the genetic basis for the differences in the cold tolerance of Xian/indica and Geng/japonica rice seedlings is still largely unknown. In this study, an RIL population was generated by crossing of the cold-tolerant japonica variety Nipponbare and the cold-sensitive indica variety WD16343 for BSA-seq analysis, and a major cold tolerance QTL qCTS11 was identified on chromosome 11.

Unveiling Cu Nanoparticles Formed During Li Deposition in Anode-Free Batteries.

Developing high-energy-density Li metal batteries is essential for sustainable progress, necessitating in-depth studies of complex battery reactions. The presence of metallic Cu impurities detrimentally impacts battery performance, leading to issues such as self-discharging and internal soft short-circuit. Nevertheless, their formation mechanism and structural characteristics have not been revealed clearly.

Clustering Analysis of Natural D-borneol Resource Plants Based on Simple Sequence Repeat (SSR) Markers, Leaf Morphology, and Chemical Composition.

D-borneol is a double-loop monoterpene with a wide use in the pharmaceutical, food, and cosmetics industries. Natural D-borneol can be extracted from branches and leaves of D-borneol resource plants. With the widespread use of natural D-borneol, the identification of D-borneol resource plants and the protection of germplasm resources have become the focus of research.

In Vitro Profiling of Toxicity Effects of Different Environmental Factors on Skin Cells.

The skin is constantly exposed to a variety of environmental threats. Therefore, the influence of environmental factors on skin damage has always been a matter of concern. This study aimed to investigate the cytotoxic effects of different environmental factors, including cooking oil fumes (COFs), haze (PM), and cigarette smoke (CS), on epidermal HaCaT cells and dermal fibroblast (FB) cells.

Bisphenol chemicals in colostrum from Shanghai, China during 2006-2019: Concentration, temporal variation, and potential influence on birth parameters.

Bisphenol A (BPA) and its alternatives bisphenol S (BPS) and bisphenol F (BPF) are identified as endocrine disruptors that have negative impacts on infant growth. Their temporal variations in human milk and potential effects on fetal growth are not well known. In this study, colostrum collecting at four time points between 2006 and 2019 and paired urine in 2019 from Shanghai, China, were analyzed for eight bisphenols.

Enhancing UV-C Photoelectron Lifetimes for Avalanche-like Photocurrents in Carbon-Doped BiOCl Nanosheets.

Interlayer electric fields in two-dimensional (2D) materials create photoelectron protecting barriers useful to mitigate electron-hole recombination. However, tuning the interlayer electric field remains challenging. Here, carbon-doped BiOCl (C:BiOCl) nanosheets are synthesized using a gas phase protocol, and n-type carriers are acquired as confirmed by the transconductance polarity of nanosheet field effect transistors.

Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant .

is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for in the last five years, and focus on the new interesting advances including the combination of phage and other substances (like photosensitizer), and the phage encapsulation (by microparticle, hydrogel) in delivery.

In Silico Genome-Wide Mining and Analysis of Terpene Synthase Gene Family in Hevea Brasiliensis.

Terpene synthases (TPSs) catalyze terpenoid synthesis and affect the intracellular isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) concentration. In this study, we mined the in silico genome-wide TPS genes of Hevea brasiliensis and identified 47 full-length TPS genes. They had DDXXD, DXDD, NSE/DTE, RR(X)8 W, EA(X)W, and other conserved motifs.

Full-Length Transcriptome Sequencing Combined with RNA-Seq to Analyze Genes Related to Terpenoid Biosynthesis in .

is a cinnamomum plant rich in natural D-borneol. Natural D-borneol is a bicycle monoterpenoid compound widely used in the food, pharmaceutical, and cosmetic industries. Therefore, analyzing the biosynthesis mechanism of natural D-borneol in at the molecular level is helpful for directional breeding in the future and further development and utilization of and its related gene resources.

Organophosphate tri- and diesters in source water supply and drinking water treatment systems of a metropolitan city in China.

The water contaminations with organophosphate triesters (tri-OPEs) and diesters (di-OPEs) have recently provoked concern. However, the distributions of these compounds in natural water sources and artificial water treatment facilities are poorly characterized. A comprehensive study was therefore performed to measure their concentrations in a water source, a long-distance water pipeline, and a drinking water treatment plant (DWTP).

Elastic mechanics solution of thermal expansion of bi-material curved beam and its application to negative thermal expansion metamaterials.

Thermal stress impacts various engineering fields significantly, such as aerospace and precision instruments. This adverse effect can be greatly reduced, if not eliminated, by the application of micro-thermal expansion materials, and bi-material beams are widely utilized in the design of micro-thermal expansion structures, thereby exhibiting great application potentials. The elasticity solution of bi-material curved beam under free thermal expansion has been proposed by scholars.

Does City Public Service Distance Increase Sense of Gain to Public Health Service? Evidence from 1394 Migrant Workers in Six Provinces.

Increasing the well-being of migrant workers is one of the key objectives of promoting equality and safe, people-oriented, and sustainable social development, as well as inclusive globalization. With the equalization reform of the public health system and the reduction of frictions between cities, the well-being of the sense of gain to public health service (SGPHS) of migrant workers has attracted widespread attention. Based on the migrant worker thematic survey data in 2017 and the city statistical data in six destination cities, this study constructed and measured the sense of gain to public health service index and city public service distance index, and then studied the effects of city public service distance on the SGPHS of migrant workers and the heterogeneous effect.

Interaction between bacterial diversity and biogenic amines production in a salted mackerel stored at soft frozen (-7℃-0℃) storage.

The bacterial diversity of salted mackerel "one-night courtyard" at soft frozen area (-7℃-0℃) storage was studied. The fish samples at 0, 14, 21, 28, and 35 days were analysis for bacterial structure using high-throughput sequencing technologies (HTS) and biogenic amines using high-performance liquid chromatography (HPLC). The analysis results of HTS showed that the dominant bacteria species was varied gradually following with storage time.

[Cloning and expression pattern of phosphate transporter 1;1 cDNA sequence from Spirodela polyrrhiza].

Spirodela polyrrhiza is a floating plant widely used in biomass utilization and eutrophication phytoremediation. It becomes a common aquatic plant everywhere with the increasingly serious eutrophication. It has been reported that S.

A 1232 bp upstream sequence of glutamine synthetase 1b from Eichhornia crassipes is a root-preferential promoter sequence.

Background: Glutamine synthetase (GS) acts as a key enzyme in plant nitrogen (N) metabolism. It is important to understand the regulation of GS expression in plant. Promoters can initiate the transcription of its downstream gene.

[Comparison of 127° small and 135° large stem angle prostheses in total hip arthroplasty].

Objective: To investigate the effect of total hip arthroplasty(THA) with the prosthesis of 127° small neck stem angle and 135° large neck stem angle.

Methods: From January 2014 to June 2016, 84 patients with THA were selected, including 44 males and 40 females, aged 45 to 72(53.4±8.

Effects of public health policies on the health status and medical service utilization of Chinese internal migrants.

This paper examines the effects of the "Equalization Program of Basic Public Health and Family Planning Services for Migrants" (EHFPSM), a novel internal migrant-targeted public health policy, of China implemented in 2013. By combining the individual-level data from the "China Migrants Dynamic Survey" and city-level statistical data, we find that EHFPSM contributes to a 6.9% statistically significant increase in the probability of electronic health records coverage and a 7.

Enhanced extraction efficiency of natural D-borneol from Mei Pian tree leaves pretreated with deep eutectic solvents.

Stems and leaves of Mei Pian tree can be used to extract natural D-borneol. In this study, a variety of deep eutectic solvents (DESs) based on choline chloride were used to pretreat leaves of Mei Pian tree, from which natural D-borneol was extracted by Soxhlet extraction. The extraction efficiency of most pretreated leaves was higher than that of the unpretreated leaves, and that pretreated by DES based on choline chloride and sucrose or choline chloride and glycol was maximal.

Sinomenine ameliorates intervertebral disc degeneration via inhibition of apoptosis and autophagy and .

Background: Aberrant apoptosis in nucleus pulposus (NP) cells is the primary cause of intervertebral disc degeneration (IDD). In contrast, a large number of studies have confirmed that autophagy may protect NP cells from apoptosis. Sinomenine is an alkaloid monomer, which has been reported to stimulate cell autophagy.

Rice straw pretreatment using deep eutectic solvents with different constituents molar ratios: Biomass fractionation, polysaccharides enzymatic digestion and solvent reuse.

Lignocellulosic biomass pretreatment with deep eutectic solvents (DESs) is a promising and challenging process for production of biofuels and valuable platform chemicals. In this work, rice straw was mainly fractionated into carbohydrate-rich materials (CRMs) and lignin-rich materials (LRMs) by 90% lactic acid/choline chloride (LC)-water solution with different molar ratio of hydrogen bond donor (HBD, lactic acid) and hydrogen bond acceptor (HBA, choline chloride). It was found that high HBD/HBA molar ratio of DESs was favorable for achieving CRMs and LRMs with high purity, and both HBD and HBA were responsible for effective biomass fractionation possibly due to their synergistic effect on highly efficient breakage of the linkage between hemicellulose and lignin and thus lignin extraction.

Effects of different forms of nitrogen on rhizosphere microbial community structure of Eichhornia crassipes (Pontederiaceae).

Rhizosphere microbial communities are important for phytoremediation, plant nutrition, health and metabolism. Many factors, including plant species, pH and nutritional factors influence rhizosphere micro- biology. In this study, we analysed the effects of different forms of nitrogen on the structures of rhizosphere microbial communities of E.