Ecological similarity governs non-native fish establishment while human pressure and native diversity shape invasion richness.

Biological invasions by non-native fish species pose a major threat to global freshwater ecosystems. However, our understanding of why invaders establish in some communities but not others (i.e.

Leflunomide-Mediated Immunomodulation Inhibits Lesion Progression in a Vitiligo Mouse Model.

Autoimmune CD8 T cell-driven melanocyte destruction constitutes a key pathogenic mechanism in the development of vitiligo. Therefore, the pharmacological inhibition of CD8 T cell effector functions and skin trafficking is a clinically viable therapeutic strategy. This study investigates leflunomide (LEF), an immunomodulatory drug with established safety in autoimmune diseases, for its therapeutic potential in a tyrosine-related protein (TRP) 2-180-induced vitiligo mouse model.

Comparison of short-term effectiveness between unilateral biportal endoscopic and MED-assisted transforaminal lumbar interbody fusion for mild single-segment lumbar spondylolisthesis.

Objectives: The purpose of this study was to compare the short-term clinical efficacy of unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) versus minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) with microendoscopic discectomy (MED) for lumbar spondylolisthesis.

Methods: The patients were divided into MIS-TLIF group and UBE-TLIF group according to the surgical procedures. The two groups were compared in terms of surgery-related parameters, postoperative functional scores and complications.

Built-in electric field of AgSe thermoelectric effect activated persulfate for humic acid decomposition in water: Molecular transformation mechanism.

Water temperature fluctuations directly impact pollutant decomposition processes in wastewater. Thermoelectric effect is considered an alternative to utilize these temperature variations for pollution control. In this study, a system for persulfate (PS) activation by AgSe thermoelectric catalyst under water temperature gradients (Ag₂Se/Δ/PS) was developed for humic acid (HA) degradation in water.

CD27 and GZMK as Co-Biomarkers in Rheumatoid Arthritis and Crohn's disease and Mediate Immune Imbalance.

Background: Studies have found similar immune responses, genetic susceptibility, and inflammatory mediators between Rheumatoid arthritis (RA) and Crohn's disease (CD), but these findings are controversial.

Methods: The Gene Expression Omnibus (GEO) was utilized to get microarray data. Differentially expressed genes (DEGs) in individuals with CD and RA were identified.

Chromosome-level genome assembly reveals adaptive evolution of the invasive Amazon sailfin catfish (Pterygoplichthys pardalis).

Catfish represents a diverse lineage with variable number of chromosomes and complex relationships with humans. Although certain species pose significant invasive threats to native fish populations, comprehensive genomic investigations into the evolutionary adaptations that contribute to their invasion success are lacking. To address this gap, our study presents a high-quality genome assembly of the Amazon sailfin catfish (Pterygoplichthys pardalis), a member of the armored catfish family, along with a comprehensive comparative genomic analysis.

Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway.

Gallic acid (GA), a natural organic phenolic compound, is an abundant plant food bioactive substance present in many medicinal herbs. GA has anti-oxidative, anti-inflammatory and anticancer activities on multiple metabolic disorders. The present study was carried out to uncover the alleviating effects of GA on metabolic dysfunction-associated steatohepatitis (MASH) and the underlying mechanisms of its action.

Determination of low-level Sr in large volumes of seawater.

The release of radioactive substances into the environment, particularly the discharge of contaminated water from the Fukushima Daiichi Nuclear Power Plant, has raised public concern. Sr, a highly hazardous radionuclide, remains a significant challenge for accurate determination in environmental seawater due to its low concentration. In this work, an effective co-precipitation of Sr with SrCO and CaCO was established for pre-concentration of Sr from a large volume of seawater up to 45 L by using an appropriate concentration of (NH)CO instead of NaCO followed by removal of calcium by hydroxide precipitation.

Multiple cell-type interactions drive invariant NKT cell hepatitis.

Background: α-Galactosylceramide (α-Galcer), a specific ligand for invariant natural killer T (NKT) cell activation, has been actively investigated in clinical trials such as antitumor therapy; however, treatment with α-Galcer is well known to induce acute hepatitis due to enriched NKT cells in the liver. The molecular mechanisms underlying NKT-mediated hepatitis still remain obscure. The object of this study was to investigate whether and how myeloid cells affect NKT-mediated hepatitis.

Longitudinal reconfiguration of multifaceted fish α and β diversity triggered by non-native species invasion in tropic rivers of Hainan Island.

Human-mediated fish invasions have reconfigured the native fish faunas throughout the freshwater ecosystems worldwide. Beyond the well-documented homogenization reported in temperate basins, our knowledge on how multifaceted biodiversity response to fish invasions in tropic rivers remains poorly understood. It is also hanged in doubt that how fish invasions modify the longitudinal patterns of fish faunas under the concept of river continuum.

Rapid charge transfer and O selective catalysis induced by B-doped nanoconfined reactor realized complete Cu-EDTA decomplexation: Significant role of BC conformation.

Nanoconfinement strategy that overcomes the defects of conventional heterogeneous catalysts in electron and mass transport provides a new outlet to enhance REDOX processes. Nonetheless, limitations in the activity and selectivity of effective catalytic sites are still the drawbacks of nanoconfined catalysts. In this study, a B-doped carbon nanotubes-confined-FeO catalyst (BFe@CNTs-L) coupled with a dielectric barrier discharge (DBD) plasma system (DBD/BFe@CNTs-L) was developed for Cu-EDTA removal.

Efficient dual-phase PtNiCuMnMo high-entropy alloy electrocatalyst for alkaline hydrogen evolution reaction.

The realisation of high-performance cathodic hydrogen evolution reaction (HER) is of considerable importance for the development of the nascent hydrogen economy. Herein, we develop a dual-phase PtNiCuMnMo high-entropy alloy (HEA) showing excellent alkaline HER performance with an overpotential of as low as 44 mV at a current density of 10 mA/cm. Additionally, the PtNiCuMnMo HEA catalyst maintains stability after 72 h at a current density of 200 mA/cm.

A combined proteomic and metabolomic analysis of the early aborted embryonic tissues with maternal COVID-19 infection.

COVID-19 still spreads worldwide, and repeated infections are hard to avoid. Maternal infection during pregnancy is associated with adverse maternal and neonatal outcomes. Our study used a multi-omics profiling method to explore the proteome and metabolome alteration in early embryonic development after COVID-19 infection.

Increased caveolin 1 by human antigen R exacerbates -induced atherosclerosis by modulating oxidative stress and inflammatory responses.

Objective: Many different types of infectious oral diseases have been identified clinically, including chronic periodontitis. is the main pathogen causing chronic periodontitis, which is closely related to atherosclerosis (AS) and can promote the expression levels of caveolin 1 (Cav-1) and induced ribonucleic acid (RNA)-binding protein human antigen R (HuR). However, the roles of Cav-1 and its relationship with HuR in -mediated AS progression remain largely unknown.

Ambient PMs pollution, blood pressure, potential mediation by short-chain fatty acids: A prospective panel study of young adults in China.

Background: The concurrent effects of particulate matter (PM) on both blood pressure (BP) and short-chain fatty acids (SCFAs) are insufficiently explored, with limited research on the potential mediating roles of SCFAs.

Methods: In this prospective panel study with 4 follow-ups, we recruited 40 college students in Hefei, China, to assess the impacts of short-term exposure to PM (aerodynamic diameter ≤10 μm (PM), ≤2.5 μm (PM), and ≤1 μm (PM)) on BP and SCFAs, along with potential mechanisms.

Migration of cervical spine screws to the sacral canal: a case report.

Cervical open door laminoplasty is widely used in multilevel decompression, which is a motion-sparing decompression treatment option for multilevel cervical myelopathy. Implant distance migration in cervical laminoplasty has not been reported. A 61-year-old woman underwent cervical laminoplasty, three months postoperatively, she experienced left shoulder pain and left upper limb pain, and underwent cervical magnetic resonance imaging, which showed no abnormalities.

Hepatic ectopic pregnancy with hemorrhage secondary diaphragmatic adhesion: A case report.

Background: Primary abdominal pregnancy is an extremely rare form of ectopic pregnancy. Ectopic pregnancies that occur in the liver and diaphragm are even rarer, limited case reports are available in the literature.

Case Summary: A woman of childbearing age was transferred to the emergency department due to lumbar and abdominal pain radiating to the back toward the lower right.

Engineering Ag-Decorated Graphene Oxide Nano-Photothermal Platforms with Enhanced Antibacterial Properties for Promoting Infectious Wound Healing.

Introduction: Graphene oxide (GO) nanoparticles have emerged as a compelling photothermal agent (PHTA) in the realm of photothermal antibacterial therapy, owing to their cost-effectiveness, facile synthesis, and remarkable photostability. Nevertheless, the therapeutic efficacy of GO nanoparticles is commonly hindered by their inherent drawback of low photothermal conversion efficiency (PCE).

Methods: Herein, we engineer the Ag/GO-GelMA platform by growing the Ag on the surface of GO and encapsulating the Ag/GO nanoparticles into the GelMA hydrogels.

Engineering electronic structures and oxygen vacancies of manganese-doped nickel molybdate porous nanosheets for efficient oxygen evolution reaction.

The design strategy of designing effective local electronic structures of active sites to improve the oxygen evolution reaction (OER) performance is the key to the success of sustainable alkaline water electrolysis processes. Herein, a series of manganese-doped nickel molybdate porous nanosheets with rich oxygen vacancies on the nickel foam (Mn-NiMoO/NF PNSs) synthesized by the facile hydrothermal and following annealing routes are used as high-efficiency and robust catalysts towards OER. By virtue of unique nanosheets architectures, more exposed active site, rich oxygen vacancies, tailored electronic structures, and improved electrical conductivity induced by Mn incorporation, as predicted, the optimized Mn-NiMoO/NF PNSs catalyst exhibits superior the OER performance with a low overpotential of 211 mV at 10 mA‧cm, a small Tafel slope of 41.

CoSFISH: a comprehensive reference database of COI and 18S rRNA barcodes for fish.

Fish, being a crucial component of aquatic ecosystems, holds significant importance from both economic and ecological perspectives. However, the identification of fish at the species level remains challenging, and there is a lack of a taxonomically complete and comprehensive reference sequence database for fish. Therefore, we developed CoSFISH, an online fish database.

Hepatitis B: Model Systems and Therapeutic Approaches.

Hepatitis B virus (HBV) infection is a major global health issue and ranks among the top causes of liver cirrhosis and hepatocellular carcinoma. Although current antiviral medications, including nucleot(s)ide analogs and interferons, could inhibit the replication of HBV and alleviate the disease, HBV cannot be fully eradicated. The development of cellular and animal models for HBV infection plays an important role in exploring effective anti-HBV medicine.