Publications by authors named "Linzhi Jiang"

Objective: This study aims to explore and investigate the positive experiences and the benefit finding among family caregivers of patients with chronic obstructive pulmonary disease (COPD) during the caregiving process.

Design: A semi-structured interview was conducted with eight caregivers of individuals diagnosed with COPD, employing a phenomenological approach typical of qualitative research. The interview data were analysed using the Colaizzi's 7-step method, which facilitated a systematic examination, summarisation and identification of themes within the data.

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Traumatic Brain Injury (TBI), particularly in moderate-to-severe cases, remains a leading cause of long-term disability worldwide, affecting over 64 million individuals annually. Its complex and multifactorial nature demands an integrated, multidisciplinary rehabilitation approach to address the diverse physical, cognitive, behavioral, and psychosocial impairments that follow injury. We conducted a structured literature search using PubMed, Scopus, and Web of Science databases for suitable studies.

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Objective: This study aimed to develop Benefit Finding intervention protocols for colorectal cancer patients on psychological management in China.

Methods: We created an initial draft of such a protocol through a comprehensive literature review and group discussions. A two-round Delphi study via WeChat correspondence was conducted, with a group of 14 Chinese experts.

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Article Synopsis
  • - The study investigates how changes in peripheral adaptive immune cells affect metabolic profiles in a ketamine-treated mouse model of schizophrenia, suggesting a link between immune responses and mental health issues.
  • - Using flow cytometry and advanced metabolomics techniques, researchers found an increase in CD3 T cells and notable alterations in amino acid metabolism, particularly elevated levels of glycine, alanine, asparagine, and aspartic acid.
  • - Although the research highlights the role of peripheral amino acid metabolism in ketamine-induced schizophrenia symptoms, it has yet to pinpoint the specific metabolic pathways responsible for these changes.
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Schizophrenia, a complex psychiatric disorder with diverse symptoms, has been linked to ketamine, known for its N-methyl-D-aspartate (NMDA) receptor antagonistic properties. Understanding the distinct roles and mechanisms of ketamine is crucial, especially regarding its induction of schizophrenia-like symptoms. Recent research highlights the impact of ketamine on key brain regions associated with schizophrenia, specifically the prefrontal cortex (PFC) and hippocampus (Hip).

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  • The study aimed to evaluate the effectiveness of using small incision lenticule extraction (SMILE)-derived patches for repairing the cornea after dermoid excision, with the patches secured using fibrin glue.
  • Seventeen patients underwent this procedure, and over an average follow-up of about 11.5 months, the patches remained securely in place and clear, leading to significant improvements in best-corrected visual acuity (BCVA) for some patients.
  • The technique was found to be safe, with some minor complications addressed effectively, and all participating patients reported satisfaction with the cosmetic results post-surgery.
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Brain-computer interface (BCI) technology allows people with disabilities to communicate with the physical environment. One of the most promising signals is the non-invasive electroencephalogram (EEG) signal. However, due to the non-stationary nature of EEGs, a subject's signal may change over time, which poses a challenge for models that work across time.

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Y-chromosome-specific short tandem repeat loci (Y-STRs) are commonly analysed in forensic science for paternity testing, familial searches, and, in sexual assault cases, to determine male DNA identity from mixed sources with high background female DNA content. The Microreader 40Y ID System is a six-dye multiplex amplification kit that contains 17 Y-STR loci from the Yfiler Plus PCR Amplification Kit and the powerplex Y23 system (DYS19, DYF385a/b, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS549, DYS635(Y GATA C4), DYS643, Y GATA H4, DYS460, DYS481, DYS533, DYF387S1, DYS449, DYS518, DYS570, DYS576, and DYS627), plus six high polymorphic loci (DYS444, DYS447, DYS557, DYS596, DYS527 a/b) as well as 4 additional candidate Y-STR loci (DYS593, DYF404S1, DYS645) and a Y-Indel loci (Rs2032678), thereby providing greater efficiency, compatibility, and accuracy. The Microreader 40Y ID System can directly amplify markers from blood or saliva on filter paper or FTA cards, without template extraction or purification, and can also be used for extracted DNA templates.

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Background: This study aimed to assess the relationship between the use of dexmedetomidine and the incidence of acute kidney injury (AKI) in septic shock patients undergoing mechanical ventilation and reveal the potential mechanism.

Methods: Septic shock patients undergoing mechanical ventilation were included. Patients were randomized into two groups including propofol group and dexmedetomidine group.

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