Objective: This study aims to explore and investigate the positive experiences and the benefit finding among family caregivers of patients with chronic obstructive pulmonary disease (COPD) during the caregiving process.
Design: A semi-structured interview was conducted with eight caregivers of individuals diagnosed with COPD, employing a phenomenological approach typical of qualitative research. The interview data were analysed using the Colaizzi's 7-step method, which facilitated a systematic examination, summarisation and identification of themes within the data.
Traumatic Brain Injury (TBI), particularly in moderate-to-severe cases, remains a leading cause of long-term disability worldwide, affecting over 64 million individuals annually. Its complex and multifactorial nature demands an integrated, multidisciplinary rehabilitation approach to address the diverse physical, cognitive, behavioral, and psychosocial impairments that follow injury. We conducted a structured literature search using PubMed, Scopus, and Web of Science databases for suitable studies.
View Article and Find Full Text PDFObjective: This study aimed to develop Benefit Finding intervention protocols for colorectal cancer patients on psychological management in China.
Methods: We created an initial draft of such a protocol through a comprehensive literature review and group discussions. A two-round Delphi study via WeChat correspondence was conducted, with a group of 14 Chinese experts.
J Psychiatry Neurosci
December 2024
Schizophrenia, a complex psychiatric disorder with diverse symptoms, has been linked to ketamine, known for its N-methyl-D-aspartate (NMDA) receptor antagonistic properties. Understanding the distinct roles and mechanisms of ketamine is crucial, especially regarding its induction of schizophrenia-like symptoms. Recent research highlights the impact of ketamine on key brain regions associated with schizophrenia, specifically the prefrontal cortex (PFC) and hippocampus (Hip).
View Article and Find Full Text PDFEntropy (Basel)
January 2022
Brain-computer interface (BCI) technology allows people with disabilities to communicate with the physical environment. One of the most promising signals is the non-invasive electroencephalogram (EEG) signal. However, due to the non-stationary nature of EEGs, a subject's signal may change over time, which poses a challenge for models that work across time.
View Article and Find Full Text PDFInt J Legal Med
January 2021
Y-chromosome-specific short tandem repeat loci (Y-STRs) are commonly analysed in forensic science for paternity testing, familial searches, and, in sexual assault cases, to determine male DNA identity from mixed sources with high background female DNA content. The Microreader 40Y ID System is a six-dye multiplex amplification kit that contains 17 Y-STR loci from the Yfiler Plus PCR Amplification Kit and the powerplex Y23 system (DYS19, DYF385a/b, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS549, DYS635(Y GATA C4), DYS643, Y GATA H4, DYS460, DYS481, DYS533, DYF387S1, DYS449, DYS518, DYS570, DYS576, and DYS627), plus six high polymorphic loci (DYS444, DYS447, DYS557, DYS596, DYS527 a/b) as well as 4 additional candidate Y-STR loci (DYS593, DYF404S1, DYS645) and a Y-Indel loci (Rs2032678), thereby providing greater efficiency, compatibility, and accuracy. The Microreader 40Y ID System can directly amplify markers from blood or saliva on filter paper or FTA cards, without template extraction or purification, and can also be used for extracted DNA templates.
View Article and Find Full Text PDFAnn Palliat Med
March 2020
Background: This study aimed to assess the relationship between the use of dexmedetomidine and the incidence of acute kidney injury (AKI) in septic shock patients undergoing mechanical ventilation and reveal the potential mechanism.
Methods: Septic shock patients undergoing mechanical ventilation were included. Patients were randomized into two groups including propofol group and dexmedetomidine group.