Substantial consumption of fossil fuels causes an increase in CO emissions and intensifies global pollution problems, such as the greenhouse effect. Recently, a new type of ultra-low-density porous material, metal-organic frameworks (MOFs), has been developed for the photocatalytic conversion of CO. Herein, a composite photocatalytic catalyst based on NH-MIL-125(Ti) and reduced graphene oxide (rGO@NH-MIL-125) was fabricated through a facile "one-pot" process.
View Article and Find Full Text PDFEnviron Geochem Health
May 2020
Along with iron and steel production, large amount of slag is generated. Proper management on the iron- and steelmaking slag is highly demanded due to the high cost of direct disposal of the slag to landfill, which is the most adopted management approach. In this article, the potential application of iron- and steelmaking slag has been reviewed, which included the slag utilization in construction as cement and sand, in water, soil, and gas treatment, as well as in value material recovery.
View Article and Find Full Text PDFFilled hydrogel particles can be fabricated by incorporating an oil-in-water emulsion into portions of separated incompatible lower and upper phases together and remixing with later acidification to pH 5.0. The purpose of present study was to investigate the influence of different heat-denatured whey protein concentrates (HWPC)/high methoxy pectin (HMP) mass ratios (1:1, 2:1, 3:1, 4:1, and 5:1) of phase separated systems on the physical characteristics and stabilities of filled hydrogel particles.
View Article and Find Full Text PDFNucleic Acids Res
January 2020
Transcription factors (TFs) and their target genes have important functions in human diseases and biological processes. Gene expression profile analysis before and after knockdown or knockout is one of the most important strategies for obtaining target genes of TFs and exploring TF functions. Human gene expression profile datasets with TF knockdown and knockout are accumulating rapidly.
View Article and Find Full Text PDFData Repository of Antimicrobial Peptides (DRAMP, http://dramp.cpu-bioinfor.org/ ) is an open-access comprehensive database containing general, patent and clinical antimicrobial peptides (AMPs).
View Article and Find Full Text PDFAccurate predictions of classification biomarkers and disease status are indispensable for clinical cancer diagnosis and research. However, the robustness of conventional gene biomarkers is limited by issues with reproducibility across different measurement platforms and cohorts of patients. In this study, we collected 4775 samples from 12 different cancer datasets, which contained 4636 TCGA samples and 139 GEO samples.
View Article and Find Full Text PDFAlthough LiNiCoMnO is attracting increasing attention on account of its high specific capacity, the moderate cycle lifetime still hinders its large-scale commercialization applications. Herein, the Ti-doped LiNiCoMnO compounds are successfully synthesized. The Li(NiCoMn)TiO sample exhibits the best electrochemical performance.
View Article and Find Full Text PDFThe effect of partial replacement of NaCl by using sodium substitutes (SS) on the physical, microbial and sensory characteristics of Harbin dry sausage was investigated. There were three salt formulations, including control (100% NaCl), NaCl partly substituted by KCl (SS1) (70% NaCl and 30% KCl), and NaCl partly substituted by KCl combined with other components (SS2) (70% NaCl, 20% KCl, 3.5% maltodextrin, 4% L-Lys, 1% L-Ala, 0.
View Article and Find Full Text PDFPurpose: This study aims to determine whether perioperative treatment with dexmedetomidine (DEX) during laparoscopic radical prostatectomy (LRP) can provide a reno-protective effect.
Methods: This pilot study enrolled 89 patients between 60 and 79 years old, who underwent LRP. These patients were randomly allocated into two groups: group D (n = 44) and group C (n = 45).
Theranostics
June 2020
Mitochondrial dysfunction and oxidative stress damage are hallmarks of osteoarthritis (OA). Mesenchymal stem cell (MSC)-derived exosomes are important in intercellular mitochondria communication. However, the use of MSC exosomes for regulating mitochondrial function in OA has not been reported.
View Article and Find Full Text PDFRNA epigenetics has received a great deal of attention in recent years, and the reversible N6-methyladenosine (m6A) modification on messenger RNAs (mRNAs) has emerged as a widespread phenomenon. The vital roles of m6A in diverse biological processes are dependent on many RNA-binding proteins (RBPs) with 'reader' or 'nonreader' functions. Moreover, m6A effector proteins affect cellular processes, such as stem cell differentiation, tumor development and the immune response by controlling signal transduction.
View Article and Find Full Text PDFAm J Cancer Res
April 2019
The reversible N6-methyl-adenosine (m6A) modification of messenger RNAs (mRNAs) has generated much interest in the field of stem cell modulation in recent years. Meanwhile, mounting evidence has shown that many physiopathological processes concerning cell death and survival harbor this chemical mark. Our review provides an overview of the m6A epitranscriptomic field and the updated mechanisms of m6A decoration in stem cell regulation.
View Article and Find Full Text PDFEutrophication has become great concern in recent years due to the fact that rivers, lakes, and reservoirs are the main drinking water source. Studies have been performed to enhance the removal of algae with ClO pre-oxidation, but there was high potential in the formation of chlorite and chlorate. In this study, ultra-sonication was employed to assist algae removal and control disinfection by-products formation in ClO pre-oxidation processes.
View Article and Find Full Text PDFObjective: To provide anatomic evidence of preoperative assessment of oblique lumbar interbody fusion (OLIF) for Chinese patients.
Methods: From the hospital picture archiving and communication system, 400 lumbar magnetic resonance imaging studies of adults performed between November 2016 and January 2017 were selected. L2-3, L3-4, L4-5, and L5-S1 transverse and sagittal images were studied, and anatomic parameters associated with OLIF surgery, including bare window and psoas window, were measured and recorded.
Background: As a subclass of noncoding RNAs, circular RNAs (circRNAs) have been demonstrated to play a critical role in regulating gene expression in eukaryotes. Recent studies have revealed the pivotal functions of circRNAs in cancer progression. However, little is known about the role of circTADA2A, also named hsa_circ_0043278, in osteosarcoma (OS).
View Article and Find Full Text PDFAim: To retrospectively compare the treatment effect of intraprocedural computed tomography/magnetic resonance-contrast-enhanced ultrasound (CT/MR-CEUS) fusion imaging (FI) with that of conventional ultrasound (US) in the guidance and assessment of thermal ablation of hepatocellular carcinoma (HCC).
Methods: The FI group (112 patients with 129 HCC) was treated between April 2010 and December 2012, whereas the US group (83 patients with 90 HCC) was treated between January 2008 and March 2010. Either CT/MR-CEUS FI or US was used to guide puncture, provide immediate assessment, and guide supplementary ablation.
:6-shogaol is a promising anti-cancer and anti-inflammatory agent. However, the treatment effectiveness of 6-shogaol is limited by poor water solubility, poor oral absorption and rapid metabolism. Herein, 6-shogaol loaded in micelles (SMs) were designed to improve 6-shogaol's solubility and bioavailability.
View Article and Find Full Text PDFPhotodetectors (PDs), as an indispensable component in electronics, are highly desired to be flexible to meet the trend of next-generation wearable electronics. Unfortunately, no in-depth reviews on the design strategies, material exploration, and potential applications of wearable photodetectors are found in literature to date. Thus, this progress report first summarizes the fundamental design principles of turning "hard" photodetectors "soft," including 2D (polymer and paper substrate-based devices) and 1D PDs (fiber shaped devices).
View Article and Find Full Text PDFThe components of the transforming growth factor β (TGF-β) signaling pathway in parasitic nematodes remain unknown. In this research, a type I receptor for TGF-β was isolated from the hookworm Ancylostoma caninum. The new gene was designated as Acdaf-1, a Caenorhabditis elegans daf-1 homolog.
View Article and Find Full Text PDFThe therapeutic efficiency of allogenic/intrinsic neural stem cells (NSCs) after spinal cord injury is severely compromised because the hostile niche at the lesion site incurs massive astroglial but not neuronal differentiation of NSCs. Although many attempts are made to reconstruct a permissive niche for nerve regeneration, solely using a living cell material to build an all-in-one, multifunctional, permissive niche for promoting neuronal while inhibiting astroglial differentiation of NSCs is not reported. Here, ectomesenchymal stem cells (EMSCs) are reported to serve as a living, smart material that creates a permissive, all-in-one niche which provides neurotrophic factors, extracellular matrix molecules, cell-cell contact, and favorable substrate stiffness for directing NSC differentiation.
View Article and Find Full Text PDFHuang (Reports, 5 October 2018, p. 80) report significant increases in forest productivity from monocultures to multispecies mixtures in subtropical China. However, their estimated productivity decrease due to a 10% tree species loss seems high.
View Article and Find Full Text PDFEnviron Sci Technol
February 2019
Substituting harvested wood products (HWP) for greenhouse gas (GHG) intensive nonwood materials in long-lived end uses has the potential to significantly reduce GHG emissions. To determine the mitigation effects of HWP substitution, we produced China-specific wood displacement factors (DFs) by HWP end use subcategory, defined as tonnes of carbon (tC) of reduced emissions per tC contained by the HWP substituted for typical alternative nonwood materials. The weighted average DFs for substituting HWP for nonwood materials in construction and furniture production in China were estimated to be 3.
View Article and Find Full Text PDFOxid Med Cell Longev
January 2019
Background: Liver transplantation leads to liver ischemia/reperfusion (I/R) injury, resulting in early graft dysfunction and failure. Exacerbations of oxidative stress and inflammatory response are key processes in the development of liver I/R injury. Intravenous anesthetic propofol potent effects on free radical scavenging and protects livers against I/R injury.
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