Publications by authors named "Huifen Liu"

The dissemination of scientific knowledge depends on the ability of the authors, reviewers and publishers to provide available information and data to readers and mistakes, if not discovered, it will affect the academic quality of the paper. Recently, Liu et al. published an important academic paper that investigated the adsorption behavior of thiram by four common types of microplastics (MPs) and its hazardous change after that adsorption.

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Collective migration of cancer cells, characterized by a structured leader-follower hierarchy, has emerged as a critical mechanism driving metastasis. During this process, leader cells play a pivotal role in environmental sensing, pathfinding, and signal transduction, while follower cells actively respond to these signals, facilitating stress transmission through cytoskeletal dynamics and cell-cell adhesions. Together, these interactions promote coordinated cancer invasion and metastasis.

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Objective: N-methyl-D-aspartate (NMDA) receptors are involved in the development of opioid use disorder. The (GT)n polymorphism (rs3219790) in the NMDA receptor 2A subunit gene (GRIN2A) has been proposed as a potential biomarker for risk of opioid use disorder. In this case-control study, we investigated the association between rs3219790 and opioid use disorder in a Chinese Han population.

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Anti-müllerian hormone (AMH), a member of the TGF-β family, plays a pivotal role in ovarian development by binding to its specific receptor, AMHR2. However, the function of amh/amhr2 pathway in fish ovarian development remains poorly understood. To elucidate its regulatory mechanism in largemouth bass, we identified amh and amhr2 genes from the largemouth bass genome and analyzed their expression patterns across different tissues and ovarian developmental stages.

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Methamphetamine (METH) use leads to addiction, neurotoxicity, and neuroinflammation. Ibudilast, a toll-like receptor 4 (TLR4) inhibitor, has been shown to reduce METH-induced neuroinflammation and self-administration, but its specific role in neuronal TLR4 signalling and associated behavioural outcomes remains poorly understood. This study examined Ibudilast's effects on METH reward, drug-seeking behaviour, and TLR4 signalling in a rat self-administration model.

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Objectives: To evaluate the potential of large language models (LLMs) in health education for patients with ankylosing spondylitis (AS)/spondyloarthritis (SpA), focusing on the accuracy of information transmission, patient acceptance and performance differences between different models.

Design: Cross-sectional, single-blind study.

Setting: Multiple centres in China.

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Background: Diffusion tensor imaging (DTI) analysis along the perivascular space (ALPS) index is currently widely employed to evaluate the neurophysiological activity in various neuropsychiatric disorders. However, there remains a scarcity of studies assessing the DTI-ALPS index in individuals with methamphetamine (MA) dependence. Recent studies on animals have demonstrated a significant correlation between glymphatic activity and alterations in cerebral blood flow (CBF).

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Formamidinium lead triiodide (FAPbI) is considered the most promising composition for high-performing single-junction solar cells. However, nonalloyed α-FAPbI is metastable with respect to the photoinactive δ-phase. We have developed a kinetic modulation strategy to fabricate high-quality and stable nonalloyed α-FAPbI films, assisted by cogenetic volatile iodine intercalation and decalation.

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Article Synopsis
  • The study examines how effective machine learning, particularly the Random Forest Classifier, is in predicting thyroid-specific autoantibodies in patients with Primary Sjogren's syndrome (pSS) based on clinical data.
  • A total of 96 pSS patients were analyzed through thyroid function tests to categorize them by the presence of autoantibodies, leading to the exploration of various risk factors using four different machine learning algorithms.
  • The Random Forest Classifier yielded the best results (AUC = 0.755), highlighting age, IgG levels, complement C4, and dry mouth as significant predictors for autoimmune thyroiditis in these patients.
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To achieve high power conversion efficiency in perovskite/silicon tandem solar cells, it is necessary to develop a promising wide-bandgap perovskite absorber and processing techniques in relevance. To date, the performance of devices based on wide-bandgap perovskite is still limited mainly by carrier recombination at their electron extraction interface. Here, we demonstrate assembling a binary two-dimensional perovskite by both alternating-cation-interlayer phase and Ruddlesden-Popper phase to passivate perovskite/C interface.

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Article Synopsis
  • * The research will include a systematic review of randomized controlled trials from various databases, focusing on English and Chinese studies, with two researchers evaluating the data using rigorous quality assessment tools.
  • * As the study involves existing literature, no ethical approval is necessary, and findings will be disseminated in peer-reviewed journals and academic conferences.
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N-Isopropylbenzylamine (N-ipb), a chain isomer of methamphetamine (METH) with similar physical properties, has been used as a substitute for METH in seized drug samples. However, the abuse potential of N-ipb remains unclear. Therefore, this study aimed to evaluate the abuse potential of N-ipb in comparison to METH, by using conditioned place preference (CPP), locomotor sensitization and intravenous self-administration tests.

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As a new member of the insulin-like growth factors (Igfs), Igf3 was reported to play a vital role in fish reproduction. However, in spotted steed, the function of Igf3 remains largely unknown. In the present study, we identified and characterized Igf3 gene in spotted steed.

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Metal halide perovskite solar cells (PSCs) have garnered much attention in recent years. Despite the remarkable advancements in PSCs utilizing traditional metal electrodes, challenges such as stability concerns and elevated costs have necessitated the exploration of innovative electrode designs to facilitate industrial commercialization. Herein, a physically and chemically stable molybdenum (Mo) electrode is developed to fundamentally tackle the instability factors introduced by electrodes.

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Article Synopsis
  • The Chinese soft-shelled turtle is farmed in Asia for its nutritional and medicinal benefits, and understanding its gonadal differentiation is crucial for effective breeding.
  • Histomorphology studies of embryos revealed that gonads were initially undifferentiated and began showing distinct male and female characteristics from embryonic stage 15, with key genes exhibiting sex-specific expression patterns.
  • Results indicated that certain miRNAs and chromatin remodeler genes are differentially expressed in male and female gonads, which could enhance our understanding of sex differentiation and potential sex reversal in turtles.
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  • COVID-19 started spreading around the world in December 2019, impacting people's health, including their minds.
  • Children with autism spectrum disorder (ASD) may face even bigger challenges during the pandemic.
  • This paper reviews how COVID-19 has affected these children and what factors influence their problems, helping future research on ASD.
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Wide-bandgap perovskites are promising absorbers for state-of-the-art tandem solar cells to feasibly surpass Shockley-Queisser limit with low cost. However, the commonly used mixed halide perovskites suffer from poor stability; particularly, photoinduced phase segregation. Electrospray deposition is developed to bridge the gap of growth rate between iodide and bromide components during film growth by spatially confining the anion diffusion and eliminating the kinetic difference, which universally improves the initial homogeneity of perovskite films regardless of device architectures.

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Invited for this month's cover is the group of Shun-Li Chen and Ming-De Li at the Shantou University. The image shows that one electron can be transferred easily from donor to acceptor unit to obtain integer-charge-transfer cocrystals for realizing high-efficient solar-harvesting and photothermal conversion. The Research Article itself is available at 10.

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Article Synopsis
  • The study focuses on the role of the Retinoid X receptor (RXR) in turtle reproduction, specifically examining the Rxrγ gene in the Chinese soft-shelled turtle (Pelodiscus sinensis).
  • Researchers cloned the full-length Rxrγ cDNA, creating a polyclonal antibody, and found that RXRγ protein is present in the turtles' mature gonads, with distinct expression patterns between sexes.
  • Through RNA interference experiments, it was confirmed that Rxrγ plays a crucial role in gonadal differentiation by affecting the expression of various genes, suggesting its involvement in reproductive development in turtles.
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Inspired by the concept of ionic charge-transfer complexes for the Mott insulator, integer-charge-transfer (integer-CT) cocrystals are designed for NIR photo-thermal conversion (PTC). With amino-styryl-pyridinium dyes and F4TCNQ (7,7',8,8'-Tetracyano-2,3,5,6-tetrafluoroquinodimethane) serving as donor/acceptor (D/A) units, integer-CT cocrystals, including amorphous stacking "salt" and segregated stacking "ionic crystal", are synthesized by mechanochemistry and solution method, respectively. Surprisingly, the integer-CT cocrystals are self-assembled only through multiple D-A hydrogen bonds (C-H⋅⋅⋅X (X=N, F)).

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Purpose: Opioid use disorder is a significant global problem. Chronic heroin use is associated with impairment of cognitive function and conscious control ability. The cholinergic system can be disrupted following heroin administration, indicating that activation of the cholinergic system may prevent chronic heroin misuse.

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The neurobiological mechanism underlying methamphetamine (MA) use disorder was still unclear, and no specific biomarker exists for clinical diagnosis of this disorder. Recent studies have demonstrated that microRNAs (miRNAs) are involved in the pathological process of MA addiction. The purpose of this study was to identify novel miRNAs for the diagnosis biomarkers of MA user disorder.

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Introduction: Depression is the most dominant non-motor symptom of Parkinson's disease (PD), with a prevalence of up to 50%, and can lead to a range of psychiatric and psychological problems that can affect quality of life and overall functioning. While several randomised controlled trials (RCTs) have tested the effect of certain non-pharmacological interventions on the outcome of PD depression symptoms, the comparative benefits and harms of these remain unclear. We will conduct a systematic review and network meta-analysis to compare the efficacy and safety of different non-pharmacological interventions for patients with PD depression.

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Brain white matter (WM) networks have been widely studied in neuropsychiatric disorders. However, few studies have evaluated alterations in WM network topological organization in patients with methamphetamine (MA) dependence. Therefore, using machine learning classification methods to analyze WM network topological attributes may give new insights into patients with MA dependence.

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