Publications by authors named "Guijie Chen"

In this study, the submerged fermentation of summer green tea with Aspergillus cristatus (MK346334) was developed to enhance the utilization of summer green tea and produce theabrownins (TBs) efficiently. TBs1 and TBs2 were obtained from the fermentation broth by traditional preparation method with organic solvents and an environmentally friendly dialysis method, respectively. Similar structural characteristics and 86 common thiol degradation products identified demonstrated that the dialysis method could substitute organic solvents for removing small molecules.

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Background: Camellia oleifera shells (COS) are a by-product of camellia oil processing and are rich in polyphenols. To date, the polyphenols extracted from COS have not been fully developed. In this study, two polyphenol fractions, referred to as 20P and 40P, were obtained by sequentially eluting the COS crude extract from an AB-8 macroporous resin column using ethanol at concentrations of 20% and 40% with different polarities.

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Fluoride (F) is a nonessential but potentially harmful element for plants, especially when present in excess. The tea plant is known for its ability to hyperaccumulate F from the soil and eventually accumulates in the leaves; however, how the tea plant transports F to the leaves remains unclear. Here, we found that Se can significantly decrease the transport efficiency of F from root to leaf.

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This study investigated the sensory characteristics of black tea milk teas (BTMTS) and explored their key aroma qualities. Through sensory evaluation, the mouthfeel, taste, and aroma profiles of BTMTS were identified, and the sensory wheel for BTMTS was constructed. Combining three aroma extraction methods (SPME, SBSE, SAFE), the volatile components of milk tea were comprehensively extracted.

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Queen bee larvae (QBL) have been consumed as both a traditional food and medicine in China for thousands of years; however, their specific benefits for human health, particularly their potential anti-obesity property, remain underexplored. This study investigated the anti-obesity effect of QBL freeze-dried powder (QBLF) on high-fat diet (HFD) induced obesity in mice and explored the underlying mechanisms. Our findings showed that QBLF effectively reduced body weight, fasting blood glucose levels, lipid accumulation, and inflammation in HFD mice.

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Polyacylated anthocyanins are known for their enhanced stability and immunosuppressive properties. Although peonidin-3-O-(3,6-O-dimalonyl-β-D-glucoside) (P3GdM) from black corncobs has demonstrated notable antibacterial and stress-resistance effects in plants, its regulatory role in inflammatory bowel disease (IBD) remains unexplored. In this study, P3GdM was isolated from black corncobs, and its potential as a treatment for dextran sulfate sodium (DSS)-induced colitis in mice was evaluated.

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Black corn (Zea mays L.), native to Latin America, has been cultivated for millennia and holds significant cultural and culinary importance. While anthocyanins are well-characterized flavonoids in black corn, acylated derivatives remain insufficiently explored.

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Article Synopsis
  • Dietary polyphenols are plant compounds with potential health benefits, particularly in preventing and treating chronic diseases like Inflammatory Bowel Disease (IBD).
  • Despite their promise, research is hindered by challenges in analyzing their structure and limitations of current models.
  • This review highlights the interactions between dietary polyphenols, bile acids, gut microbiota, and the gut-brain axis, paving the way for better understanding and future research in their therapeutic roles.
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Royle ex Wight, commonly known as "Baishouwu," has been traditionally used in China for its medicinal and dietary benefits. Despite its long history of use, the potential therapeutic effects of in the treatment of colitis have not been fully investigated. This study aims to evaluate the effects of the water extract of root on colitis and elucidate its potential mechanisms of action.

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Many consumers are adopting low-sugar and low-fat beverages to avoid excessive calories and the negative impact of high trans- and/or saturated fat on health and wellbeing. This article reviews strategies to reduce sugar, fat, and high trans- and/or saturated fat content in beverages while maintaining their desirable physicochemical and sensory attributes. It assesses the impact of various sugar and fat replacers on the aroma, taste, texture, appearance, and nutritional profile of beverages.

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To mitigate the risk associated with water-soluble fluoride in tea and to have less influence on the contents of tea infusion, a highly selective lanthanum modified silk fibroin (SF) and polyvinyl alcohol (PVA) composite film (SF/PVA-La) was prepared to remove fluoride from brick tea infusion. Notably, SF/PVA-La could remove about 48 % of the fluoride from in brick tea infusion within 30 min. Importantly, the reduction in total tea polyphenols in brick tea did not exceed 10 %, and the reduction in caffeine was only 0.

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Article Synopsis
  • Protein modification enhances the bioavailability of polyphenols, and polyphenols boost the functional properties of pea protein.
  • Four polyphenols (gallic acid, ferulic acid, catechin, and kaempferol) were chemically bonded to pea protein using methods like ultrasonic grafting, and their interaction and structural changes were analyzed.
  • The resulting conjugates displayed significantly improved antioxidant activity, thermal stability, and emulsifying properties compared to natural pea protein, making them promising for better polyphenol delivery in complex emulsions.
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Polyphenols are plant secondary metabolites that have attracted much attention due to their anti-inflammatory, antioxidant, and gut homeostasis promoting effects. However, food matrix interaction, poor solubility, and strong digestion and metabolism of polyphenols cause barriers to their absorption in the gastrointestinal tract, which further reduces bioavailability and limits polyphenols' application in the food industry. Nano-delivery systems composed of biocompatible macromolecules (polysaccharides, proteins and lipids) are an effective way to improve the bioavailability of polyphenols.

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Yeast β-glucan intervention offers a promising strategy for managing colitis; however, the mechanisms remain unknown. In the present work, the protective effects of yeast β-glucan on DSS-induced colitis in mice was evaluated, focusing on its interaction with gut microbiota. The result showed yeast β-glucan significantly alleviated colitis symptoms, evidenced by reduced weight loss, lower disease activity index (DAI) scores, and minimized intestinal damage.

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Metabolic disorders include obesity, nonalcoholic fatty liver disease, insulin resistance and type 2 diabetes. It has become a major health issue around the world. Ubiquitin-proteasome system (UPS) is essential for nearly all cellular processes, functions as a primary pathway for intracellular protein degradation.

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Introduction: The human gut microbiome plays a pivotal role in health and disease, notably through its interaction with bile acids (BAs). BAs, synthesized in the liver, undergo transformation by the gut microbiota upon excretion into the intestine, thus influencing host metabolism. However, the potential mechanisms of dicaffeoylquinic acids (DiCQAs) from Ilex kudingcha how to modulate lipid metabolism and inflammation via gut microbiota remain unclear.

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Article Synopsis
  • Endemic fluorosis is becoming a serious public health issue, with excessive fluoride intake linked to increased risk of colitis.
  • A study explored how Tea polysaccharides (TPS) can help alleviate fluoride-induced colitis by altering the gut microbiota in rats.
  • Results showed that TPS improved colitis symptoms by boosting the beneficial bacteria Limosilactobacillus vaginalis and enhancing the absorption of butyric acid, suggesting a new preventive approach against fluoride-related health issues.
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L-theanine, a unique non-protein amino acid, is an important bioactive component of green tea. Previous studies have shown that L-theanine has many potent health benefits, such as anti-anxiety effects, regulation of the immune response, relaxing neural tension, and reducing oxidative damage. However, little is known concerning whether L-theanine can improve the clearance of mitochondrial DNA (mtDNA) damage in organisms.

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In the present study, four species that could degrade Fuzhuan brick tea polysaccharide-3 (FBTPS-3) were isolated from human feces and identified to be , . The four species showed growth on FBTPS-3 as the carbon source, and showed the best capability for utilizing FBTPS-3 among the four species since could utilize more FBTPS-3 during 24 h fermentation. Moreover, the four species could metabolize FBTPS-3 and promote the production of acetic, propionic and isovaleric acids.

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A new zirconium and cerium-modified polyvinyl alcohol (PVA) sodium carboxymethyl cellulose (NaCMC) film (PVA/CMC-Zr-Ce) was synthesized thru a high-speed shear-assisted method and its adsorption for the removal of fluoride was studied, in which the NaCMC provided -COONa for ion exchange between Na and Zr-Ce, thus the loading amount of Zr-Ce on films was accordingly increased. The morphology and structure of PVA/CMC-Zr-Ce were characterized using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD). Besides, the mechanical properties, water contact angle, and swelling ratio of film were also evaluated.

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Nowadays, due to the rise of fast-food consumption, the metabolic diseases are increasing as a result of high-sugar and high-fat diets. Therefore, there is an urgent need for natural, healthy and side-effect-free diets in daily life. Whole grain supplementation can enhance satiety and regulate energy metabolism, effects that have been attributed to polyphenol content.

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Sialylated immunoglobulin G (IgG) is a vital glycoprotein in breast milk with the ability to promote the growth of in gut microbiota and relieve inflammatory bowel disease (IBD) symptoms . Here, it was found that the microcapsules with sialylated IgG could protect and release sialylated IgG with its structure and function in the intestine. Furthermore, the sialylated IgG microcapsules alleviated the clinical symptoms (body weight, feed quantity, and colon length loss), decreased disease activity index score, suppressed the production of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β, IFN-γ, and MCP-1) and endotoxin (lipopolysaccharide), and enhanced the intestinal mucosal barrier (Claudin1, Muc2, Occludin, and ZO-1) in dextran sulfate sodium (DSS)-induced colitis mice.

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In order to investigate the effects of black rice extract (BE) on the composition of oxidized myofibrillar protein (MP) gel, different concentrations of BE (0, 10, 20, 50 mg g) were analyzed experimentally. Results revealed that the addition of small doses of BE significantly inhibited the formation of carbonyl groups in oxidized MP, and improved surface hydrophobicity and gel water holding capacity. Additionally, 10 and 20 mg g BE increased the ordered structure of oxidized MP.

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American ginseng ( L.) is known for its health benefits, which are attributed to various terpenoids. However, the specific composition and activities of these terpenoids in forest-grown wild American ginseng remain understudied.

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The tea plant accumulates elevated levels of fluoride (F) from environmental sources. Drinking tea containing high F levels poses a potential threat to human health. Selenium (Se) was applied by foliar spray to investigate its effects on F accumulation and physiology in tea plant.

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