miR-340-5p alleviates the damage effect of LPS on nucleus pulposus cells by negatively regulating the expression of SOX4.

Background: Previous studies show that about 80% of lumbar disc degeneration (LDD) patients experience back or leg pain, affecting their quality of life. However, the causes of LDD are not fully understood. This study focused on exploring the expression level of miR-340-5p and SRY-related high-mobility-group box 4 (SOX4) in LDD and attempts to clarify its potential mechanism in the pathological process of LDD.

Priorities and barriers of dementia policy response and action in South Korea and China: SWOT-PESTLE-AHP model.

Introduction: The global population is experiencing an increase in the prevalence of aging and dementia. All stakeholders are required to prevent dementia, ensure that people with dementia and their caregivers live well, and receive the required care and support. This study aimed to diagnose country-level situations and the implementation of dementia policies, identify the barriers and enablers to dementia responses, and quantify the priorities needed to deliver further care and support for people living with dementia in South Korea and China.

Experimental study on mechanical performance of corrugated steel-concrete composite bridge decks.

This study investigated the mechanical performance of corrugated steel-concrete composite bridge decks featuring modified clothoid (MCL) shape shear connectors. Two deck slabs with full scales were specified as the specimens for the flexural tests. Load-slip curves, load-strain curves, and strain distribution curves were generated, and crack distribution was analyzed.

Association between life satisfaction, sleep disturbance and mental health problems among the migrant older adults with children: a conditional process analysis based on per capita bedroom area.

Background: The relationship between life satisfaction and mental health problems had been confirmed in many existed studies, but the underlying mediating and moderating effect of sleep disturbance and per capita bedroom area (PCBA) behind this association had never been identified. This study aimed to explore the mediating role of sleep disturbance and the moderating effect of PCBA on the association between life satisfaction and mental health problems.

Methods: Multistage cluster random sampling method was used to select the participants and finally 613 migrant older adults with children (MOAC) were included in the survey.

Migrant-Local Differences in the Relationship Between Oral Health, Social Support, and Loneliness Among Older Adults in Weifang, China: Cross-Sectional Study.

Background: Increased aging and accelerated urbanization have led to the migration of older adults within China. Migrant older adults (MOAs) may experience physical and psychological discomfort in influx cities, and they are a vulnerable group that has emerged in the course of fast urbanization. Previous studies have confirmed the association between oral health and loneliness as well as the relationship between social support and loneliness; however, no research has been done to clarify the underlying mechanisms and the migrant-local difference between oral health, social support, and loneliness.

Effects of nitrogen fertilizer on protein accumulation in basal-middle and apical kernels of different low nitrogen tolerant maize hybrids.

Selecting low-nitrogen(N)-tolerant maize hybrids represent an effective approach to enhancing nitrogen use efficiency grain yield. However, the impact of nitrogen fertilization on protein accumulation in low-N-tolerant hybrids remain insufficiently explored. In this paper, a two-year field orientation trial was conducted at four nitrogen fertilizer rate with the different low-N-tolerant maize hybrids.

Study of the microenvironment of the lung flora in female lung adenocarcinoma patients: from benign lesions to invasive lung adenocarcinomas.

Background: The number of female lung adenocarcinoma patients is increasing annually, but these patients are difficult to diagnose in the early stage without obvious clinical symptoms, leading to late-stage diagnoses and poor outcomes. Recent studies have shown that the lung microbiota is closely related to the occurrence and development of lung cancer, especially the characteristic changes in the lung microbiota of lung cancer patients, which opens a new research direction for the diagnosis and treatment of lung cancer. This study aimed to analyze the characteristics of the lung flora in different stages of female lung adenocarcinoma.

Microwave ablation for high-risk pulmonary nodules in patients infected with the Omicron variant of Sars-Cov-2 within 3 months: a retrospective analysis of safety and efficacy.

Introduction: To evaluate the safety and efficacy of microwave ablation (MWA) for high-risk pulmonary nodules in patients infected with the Omicron variant within 3 months, a retrospective study was conducted.

Methods: The study included patients with multiple high-risk nodules who underwent CT-guided MWA from April 2022 to April 2023. Patients were divided into an observation group and a control group.

Association between different patterns of social participation and loneliness among the Chinese older people: is there a local-migrant gap?

Background: Little empirical evidences were provided on the disparity in the level of loneliness between the migrant older with children (MOC) and their local counterpart in China. This study aimed to explore the association between social participation and loneliness and verify whether there was a local-migrant difference in this association.

Methods: A total of 1332 older people (60 +) were included in this study with 656 MOC and 676 natives.

Association between social capital, mental health, and digital health literacy among the university students in China: a multigroup analysis based on major difference.

Background: This study aimed to clarify medical-nonmedical difference on the relationship between social capital, mental health and digital health literacy of university students in China, and furtherly provide evidence-based suggestions on the improvement of the digital health literacy for the university students.

Methods: The snowball sampling method was used to collect data from the university students (including medical students and nonmedical students) through online questionnaires, and finally 1472 university students were included for the data analysis, of whom, 665 (45.18%) were medical students, 807 (54.

Inhibitory effects of cassiae semen extract on the formation of 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) in model system.

Introduction: 2-Amino-1-methyl-6-phenylimidazole [4,5-b] pyridine (PhIP), a heterocyclic amine (HAA), is found in meat products heated at high temperatures. However, PhIP is a mutagenic and potential carcinogenic compound. Cassiae semen, a type of medicine and food homology plant, is abundant in China and has been less applied for inhibiting heterocyclic amines.

Exploring COVID-19 Phobia among International Chinese College Students in South Korea Before Ending COVID-19 Restrictions.

Background: College students, considered to be the driving force of society, are highly vulnerable to COVID-19. At a time when facing a new pandemic wave in 2022, China's policy was in contrast with that of Korea. We investigated the phobia levels of international Chinese college students studying in Korea.

Erratum: Addendum: Validation of the digital health literacy assessment among the university students in China.

[This corrects the article DOI: 10.3389/fpubh.2023.

The value of a neural network based on multi-scale feature fusion to ultrasound images for the differentiation in thyroid follicular neoplasms.

Objective: The objective of this research was to create a deep learning network that utilizes multiscale images for the classification of follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA) through preoperative US.

Methods: This retrospective study involved the collection of ultrasound images from 279 patients at two tertiary level hospitals. To address the issue of false positives caused by small nodules, we introduced a multi-rescale fusion network (MRF-Net).

Validation of the digital health literacy assessment among the university students in China.

Purpose: With the development of the internet, digital health literacy (DHL) has become increasingly important for managing health. Consequently, various digital health literacy scales have been created for different groups. The purpose of this study was to verify the reliability and validity of the simplified Chinese version of the Digital Health Literacy Assessment (DHLA) scale among university students in China.

The Migrant-Local Difference in the Relationship Between Social Support, Sleep Disturbance, and Loneliness Among Older Adults in China: Cross-Sectional Study.

Background: Driven by the accelerated aging of the population of China, the number of older adults has increased rapidly in the country. Meanwhile, following children, migrant older adults (MOA) have emerged as a vulnerable group in the process of fast urbanization. Existed studies have illustrated the association between social support and loneliness and the relationship between sleep disturbance and loneliness; however, the underlying mechanisms and the migrant-local difference in the association between social support, sleep disturbance, and loneliness have not been identified.

Association between social integration and loneliness among the female migrant older adults with children: the mediating effect of social support.

Background: The number of migrant older adults with children (MOAC) in China has been increasing in recent years, and most of them are women. This study aimed to explore the mediating effect of social support between social integration and loneliness among the female MOAC in Jinan, China.

Methods: In this study, 418 female MOAC were selected using multi-stage cluster random sampling in Jinan, Shandong Province, China.

Comparative diagnostic accuracy of multiparametric magnetic resonance imaging-ultrasound fusion-guided biopsy systematic biopsy for clinically significant prostate cancer.

Purpose: To examine the accuracy of transperineal magnetic resonance imaging (MRI)-ultrasound (US) fusion biopsy (FB) in identifying men with prostate cancer (PCa) that has reached a clinically relevant stage.

Methods: This investigation enrolled 459 males. In 210 of these patients (FB group), transperineal MRI/US fusion-guided biopsies were performed on the suspicious region, and in 249 others, a systematic biopsy (SB) was performed (SB group).

Association and mediators between the impact of oral health-related quality of life and depression.

Objectives: Our research intended to explore the association and mediators (perceived social support and sleep quality) between the impact of oral health-related quality of life (OHRQoL) and depression among Chinese older adults.

Methods: A stratified, multi-stage random sampling approach was used in our study. A total of 3896 older individuals aged 60 years and older were included.

A comparative study of bibliometric analysis on old adults' cognitive impairment based on Web of Science and CNKI via CiteSpace.

Introduction: The purpose of this study was to analyze the current status, the research hot spots and frontiers of cognitive impairment (CI) on old adults from 2012 to 2022 based on Web of Science (WoS) and China National Knowledge Infrastructure (CNKI) via CiteSpace, and provide new in-sights for researchers.

Methods: The articles regarding the old adults' CI in the WoS and CNKI were retrieved from 2012 to 2022. CiteSpaceV.

Percutaneous core-needle biopsy before and immediately after coaxial microwave ablation in solid non-small cell lung cancer: the comparison of genomic testing from specimens.

Purpose: To compare the genomic testing based on specimens obtained from percutaneous core-needle biopsy (CNB) before and immediately after coaxial microwave ablation (MWA) in solid non-small cell lung cancer (NSCLC), and to investigate the diagnostic performance of CNB immediately after coaxial MWA in solid NSCLC.

Methods: Coaxial MWA and CNB were performed for NSCLC patients, with a power of 30 or 40 watts (W) in MWA between the pre- and post-ablation CNB, followed by continuous ablation after the second CNB on demand. The paired specimens derived from the same patient were compared for pathological diagnosis and genomic testing.

US of thyroid nodules: can AI-assisted diagnostic system compete with fine needle aspiration?

Objectives: Artificial intelligence (AI) systems can diagnose thyroid nodules with similar or better performance than radiologists. Little is known about how this performance compares with that achieved through fine needle aspiration (FNA). This study aims to compare the diagnostic yields of FNA cytopathology alone and combined with BRAFV600E mutation analysis and an AI diagnostic system.

The chain mediation model of social support and life satisfaction among migrant older adults with children: The role of mental health and sleep quality.

Introduction: Few studies have examined the life satisfaction of migrant older adults with children (MOAC), who emerged due to rapid urbanization and population aging in China. This study aimed to explore the chain mediating effect of mental health and sleep quality on the association between social support and life satisfaction among MOAC in Weifang, China.

Methods: A cross-sectional study was conducted using multi-stage cluster random sampling, and 613 participants were included.