Bifidobacterium breve M-16V Alleviates Cow's Milk Allergy in a Mouse Model via Gut Microbiota-Derived Indole-3-Propionic Acid-Aryl Hydrocarbon Receptor Signaling Axis.

Background: Gut microbiota plays a crucial role in the development of food allergy (FA), and probiotic intervention is a promising therapeutic strategy targeting the gut microbiota. Previous investigations have reported that some Bifidobacterium species mitigate FA by regulating the microbial composition and metabolic functions. However, the key metabolites and potential mechanisms remain poorly understood.

Assessment of Knowledge, Attitude, and Practice (KAP) Regarding Food Allergen Labeling Among Allergic Population in Jiangxi Province, China.

Food allergy is an increasing global public health concern, posing significant challenges to individual well-being and food safety. Effective management of food allergies relies heavily on the avoidance of allergens, making food allergen labeling a critical tool for allergic consumers. This study investigates the Knowledge, Attitude, and Practice (KAP) of food allergen labeling among allergic consumers in Jiangxi Province, China, with a particular focus on behavioral and motivational aspects influencing allergen avoidance.

M-16V alleviates cow's milk allergy by regulating the gut microbiota and metabolites in human microbiota-associated mice.

Cow's milk allergy (CMA) is one of the most common food allergies, especially in infants and young children. Growing evidence from animal studies has shown that some specific probiotics can alleviate CMA, but clinical evidence remains insufficient due to certain limitations. In the present study, we transplanted fecal material from three CMA children into antibiotic-pretreated mice (hum-CMA mice) to mimic the intestinal microecology of allergic individuals, followed by allergen sensitization and (.

Quantitative food allergen risk assessment: Evolving concepts, modern approaches, and industry implications.

Food safety is crucially linked to the food system, ensuring safe production, handling, and distribution to protect public health. Food allergy has been considered as a public health and food safety issue. Despite being widely regarded as a prevailing strategy for managing food allergies, strict food avoidance faces challenges due to allergen cross-contact in the food supply chain and the potential for inaccurate allergen labeling.

The Effect of Lipids on the Structure and Function of Egg Proteins in Response to Pasteurization.

In recent years, the consumption of liquid eggs has failed to meet the expectations of the public due to growing concerns regarding food safety and health. It is well known that there are interactions between the components in liquid eggs, and the interaction effect on the structure and functional properties of the proteins and antigenicity remains unclear. To investigate egg component interactions, we focused on four major egg lipids, namely phosphatidylcholine, palmitic acid, oleic acid, and linoleic acid, as well as four major egg proteins, including ovalbumin, ovotransferrin, ovomucoid, and lysozyme.

Oral exposure to ovalbumin alters glucose metabolism in sensitized mice: upregulation of HIF-1α-mediated glycolysis.

Food allergies are pathological adverse reactions against harmless dietary proteins. While studies have shown the involvement of host metabolic changes (, lipid metabolism and amino acid metabolism) in the development of food allergy (FA), the adaptive changes in glucose metabolism induced by food allergen exposure remain largely unclear. In this study, BALB/c mice were sensitized intraperitoneally with an ovalbumin (OVA)/aluminum adjuvant, followed by oral OVA challenges to induce anaphylaxis.

Precision risk assessment in wheat allergy: Leveraging advanced quantitative models for safer food consumption.

Food allergy is a significant public health concern and food safety issue. Deriving from classical toxicology principle, the food allergen risk assessment has been considered a science-based strategy to identify, quantify, and manage the food allergy risks as such risk represent a significant food safety. Moreover, the implication of the precautionary allergen labeling in most jurisdictions is voluntary, resulting potential risk to allergic consumers.

Effects of silicate stabilizers on cadmium reduction and the quality of rice grains in acidic paddy soil.

Silicate has been proven to be highly-effective at immobilizing soil heavy metals, but the effects of silicate stabilizers on rice grain cadmium (Cd) reduction and rice quality under field conditions are not clear. In this study, a field experiment was conducted over three consecutive years was conducted to examine the Cd reduction in rice grains and to reveal the potential effects of silicate stabilizers on rice grain nutrients, by setting different amounts of bentonite (B), silica‒calcium fertilizer (SC) and zeolite powder (ZP). The results revealed that the application of the B, SC and ZP significantly decreased the soil CaCl‒Cd concentration (> 39%) and significantly reduced the grain Cd concentration in both early rice (> 70%) and late rice (> 18%) under field conditions; the silicate stabilizers reduced the soil available iron (Fe) but did not limit rice grain Fe nutrition.

Oral administration of egg ovalbumin allergen induces dysregulation of tryptophan metabolism in sensitized BALB/c mice.

Food allergy (FA), triggered by specific dietary allergens, has emerged as a substantial global concern for food safety and public health. While studies have elucidated changes in immune cells and cytokines associated with allergen exposure, a comprehensive analysis of the host's metabolic features and the interaction between metabolites and the gut microbiota has not been conducted. In this study, egg allergen ovalbumin (OVA) was administered by the oral route to sensitized BALB/c mice to faithfully replicate key aspects of human FA, including severe allergic diarrhea, mast cell infiltration, and elevated levels of serum IgE, mMCPT-1, and Th2 cell hallmark cytokines (such as IL-4, IL-5, and IL-13).

Biochar assists phosphate solubilizing bacteria to resist combined Pb and Cd stress by promoting acid secretion and extracellular electron transfer.

Microorganisms have difficulty surviving and performing remediation functions in mixed systems with high concentrations of Pb and Cd. Biochar has the potential to assist microorganism remediation as an excellent adsorbent for heavy metals. In this study, pig manure biochar (PMB) was used to assist phosphorus solubilizing bacteria (PSB) to explore the mineralization protection and biofeedback mechanism of biochar on PSB under mixed stress of 1000 mg/L Pb and 500 mg/L Cd.

Elm () bark flour as a gluten substitute in gluten-free whole foxtail millet bread.

Unlabelled: Elm bark () flour is a nutritious and sustainable edible material for developing the macromolecular network in the food matrix. In this study, the effects of Elm bark flour and water addition on technological and sensory characteristics of gluten-free whole foxtail millet bread were investigated. Structural analysis methods such as SEM, X-ray diffraction, and FTIR were used to supplement the rheological properties and baking quality.

Effects of Lactobacillus casei NCU011054 on immune response and gut microbiota of cyclophosphamide induced immunosuppression mice.

Lactobacillus (L.) casei NCU011054 isolated from infant feces has been proven to be a potential probiotic in vitro. The present study aimed to investigate the effects of L.

Multi-Perspective Observation on the Prevalence of Food Allergy in the General Chinese Population: A Meta-Analysis.

Reliable estimates of the prevalence of food allergy (FA) among the general Chinese population have remained unclear. This meta-analysis aims to provide an accurate estimate of FA prevalence in China with comprehensive data. A systematic literature search was conducted in eight electronic databases, i.

Novel perspective on the regulation of food allergy by probiotic: The potential of its structural components.

Food allergy (FA) is a global public health issue with growing prevalence. Increasing evidence supports the strong correlation between intestinal microbiota dysbiosis and food allergies. Probiotic intervention as a microbiota-based therapy could alleviate FA effectively.

Wheat Amylase Trypsin Inhibitors Aggravate Intestinal Inflammation Associated with Celiac Disease Mediated by Gliadin in BALB/c Mice.

Celiac disease (CD) is an autoimmune intestinal disorder caused by the ingestion of gluten in people who carry the susceptible gene. In current celiac disease research, wheat gluten is often the main target of attention, neglecting the role played by non-gluten proteins. This study aimed to describe the effects of wheat amylase trypsin inhibitors (ATI, non-gluten proteins) and gliadin in BALB/c mice while exploring the further role of relevant adjuvants (cholera toxin, polyinosinic: polycytidylic acid and dextran sulfate sodium) intervention.

Synergetic Enhancement of Pb and Zn Adsorption onto Size-Selective Sludge Biochar Portions in Multiple Ion Solution Systems.

Particle size, one of the predominant factors that affect the adsorption capacity of biochar, has been widely investigated. However, correlative studies on a coexistence system containing various ions together with differentiated particle sizes are scarce. In this study, samples of municipal solid waste (sludge) biochar (SB) with different particle sizes were separated and examined for the adsorption performance in bi-cation (Pb/Zn) and multi-ion (Pb, Zn and Cl) systems.

Red Yeast Improves the Potential Safe Utilization of Solid Waste (Phosphogypsum and Titanogypsum) Through Bioleaching.

Phosphogypsum (PG) and titanium gypsum (TG), as a by-product (solid waste) in phosphate fertilizer and titanium dioxide industry, are causing serious environmental hazards. The resource/harmless application of PG and TG is the development trend in the future. The biological function of red yeast (Rho: ) can effectively reduce the concentration of pollutants in the environment and has the potential of biological flotation/purification of mineral solid waste.

Determination of multi-pesticide residues in green tea with a modified QuEChERS protocol coupled to HPLC-MS/MS.

A modified QuEChERS protocol, coupled to HPLC-MS/MS, was used for the analysis of 102 pesticides in green teas produced in Jiangxi province, China. For accurate quantification, matrix-matched calibration curves were applied to compensate for matrix effects. Recoveries for these pesticides ranged from 62% to 125% with relative standard deviations (RSDs) lower than 18%.

In vitro fermentation of the polysaccharides from Cyclocarya paliurus leaves by human fecal inoculums.

In vitro fermentation of polysaccharide from Cyclocarya paliurus leaves by human fecal inoculums was investigated by determining the changes in contents of neutral and reducing sugar and pH value, consumption of monosaccharide and production of short-chain fatty acids (SCFAs). During fermentation, the content of neutral sugar and reducing sugar decreased as fermentation time increased except that the content of reducing sugar increased within the fermentation time 0.5h.

Effect of gum arabic on glucose levels and microbial short-chain fatty acid production in white rice porridge model and mixed grain porridge model.

White rice porridge and mixed grain porridge, which are often consumed in many countries, were used as two models to evaluate the effects of gum arabic on glucose levels and microbial short-chain fatty acids (SCFA). Gum arabic was incorporated into the two porridges individually. Apparent viscosity of the two porridges was significantly increased, and their glucose productions during gastrointestinal digestion were notably lowered (p < 0.

Artificial simulated saliva, gastric and intestinal digestion of polysaccharide from the seeds of Plantago asiatica L.

The saliva, gastric and intestinal digestion of polysaccharide from Plantago asiatica L. seeds was investigated in vitro. It was found that salivary amylase had no effect on the polysaccharide; however, the polysaccharide was influenced in later gastrointestinal digestion.

Polysaccharide from seeds of Plantago asiatica L. increases short-chain fatty acid production and fecal moisture along with lowering pH in mouse colon.

Mice (20.0 ± 2.0 g, n = 48 per group) were given 30 days oral administration of polysaccharide from Plantago asiatica L.