Low-order digital controller design based on l parametric stability margin.

The uncertainties inherent in engineering control systems are generally intricate and multifaceted. Sometimes, the model parameters of the plants may even fluctuate significantly. To address this undesirable scenario and ensure system stability under such conditions, the controller parameters with the largest parametric stability margin in the stabilizing set should be selected.

First trimester metabolic syndrome insulin resistance index and offspring congenital heart disease risk: The mediating role of gestational diabetes mellitus.

Background: The purpose of this research was to investigate the association between the first trimester metabolic score for insulin resistance (METS-IR) index and offspring congenital heart disease (CHD), and to pay special attention to the mediating role of gestational diabetes mellitus (GDM).

Methods: A total of 21,401 women without pre-existing diabetes were enrolled in a prospective birth cohort study conducted in China. The participants were categorized into four groups based on their METS-IR index scores.

Efficacy of rTMS on SCZ symptoms: Insights from connectome mapping.

Repetitive transcranial magnetic stimulation (rTMS) is a potential treatment for schizophrenia (SCZ), yet its efficacy and underlying mechanisms remain uncertain. This study evaluates the impact of rTMS targeting the right orbitofrontal cortex (OFC) in SCZ patients and constructs a connectome atlas based on symptomatology and treatment responses. Ninety-eight SCZ patients were randomly assigned to rTMS (n = 53) or sham stimulation (n = 45) groups.

Early Resection of Kommerell Diverticulum and Revascularization in Children With Right Aortic Arch and Aberrant Left Subclavian Artery.

Background: This study aimed to evaluate outcomes for right aortic arch with aberrant left subclavian artery (LSA) in children.

Methods: This retrospective review included consecutive children undergoing repair through left thoracotomy from 2018 to 2023. Preoperative computed tomography angiography assessed airway compression severity by the tracheal cross-sectional area ratio at vascular ring level (S) and at thoracic inlet (S), with a lower S:S ratio indicating more severe airway compression.

Amphiphilic Acyclic Cucurbit[]uril: Synthesis, Self-Assembly, and Chemotherapeutic Delivery to Overcome Multidrug Resistance.

A new amphiphilic acyclic cucurbit[]uril (CB[]) is designed and synthesized. This amphiphilic acyclic CB[] could encapsulate pharmaceutical drugs via a host-guest interaction. Self-assembly of this acyclic CB[] forms spherical nanoparticles with diameters of 91 nm in water.

Discovery of an Ultralong-acting Nondepolarizing Neuromuscular Blocker That Displays Short Onset Time and On-Demand Rapid Reversal by a Biocompatible Antagonist.

The combination of ultralong-acting neuromuscular block and subsequent on-demand rapid reversal may provide prolonged surgeries with improved conditions by omitting continuous or repetitive blocker administration, enabling a more stable and predictable hemodynamic profile and eliminating residual block. For this target, we prepared 19 imidazolium-incorporated tetracationic macrocycles. In vivo studies with rats revealed that one macrocycle (IMC-14) displays extremely high blocking activity.

Supramolecular Organic Framework that Enables Multifunctional Doxorubicin Delivery, Photofrin Post-treatment Phototoxicity Inhibition, and Heparin Neutralization.

Although porous frameworks are structurally ideal for the development of biomaterials through drug adsorption, sequestration, and delivery, integration of multiple biofunctions into a biocompatible porous framework would greatly improve its potential for preclinical investigations by increasing both therapeutic value and research and development efficiency. Herein, we report the preparation of a highly biocompatible supramolecular organic framework from an imidazolium-derived tetrahedral monomer and cucurbit[8]uril. The supramolecular organic framework has been revealed to have regular intrinsic porosity and adsorb doxorubicin, photofrin, and heparins driven by hydrophobicity and/or ion-pairing electrostatic interactions.

The association between dietary carbohydrate intake and the risk of hyperlipidemia among reproductive-aged women in the US: A cross-sectional study.

Background: The association between dietary carbohydrate intake and hyperlipidemia remained incompletely understood. This study aimed to explore the association between dietary carbohydrate intake and the risk of hyperlipidemia among reproductive-aged women in the US.

Methods: The study utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2020.

Inflammatory indices-Systemic Immune-Inflammation Index (SII) and Systemic Inflammatory Response Index (SIRI)-during Pregnancy and Associations with Gestational Diabetes Mellitus.

Purpose: Gestational diabetes mellitus (GDM) is a prevalent complication during pregnancy. This study aimed to explore the associations between inflammatory indices during pregnancy and the development of GDM.

Methods: Data from the Fujian Birth Cohort Study between March 2019 and December 2022 were used.

Relationship between maternal serum uric acid in the first trimester and congenital heart diseases in offspring: A prospective cohort study.

Objective: This study aimed to investigate the relationship between maternal serum uric acid levels in the first trimester and the incidence of congenital heart diseases (CHDs) in offspring.

Methods: This prospective cohort study was conducted in the southeast of China and involved 21,425 pregnant women and their offspring in the final analysis between 2019 and 2022. Fasting blood samples from pregnant women participating in the Fujian birth cohort study (11.

Tracheoplasty should be proactively considered in the surgical strategy for treating the ring-sling complex.

Objective: To examine the safety and effectiveness of proactive tracheoplasty for pediatric ring-sling complex.

Methods: We retrospectively collected data from 304 children who were diagnosed with a ring-sling complex and underwent surgery at 3 cardiac centers in China between January 2010 and June 2023. The children were categorized into 3 surgical groups: concurrent sling and tracheal surgery (group A; n = 258), staged sling and tracheal surgery (group B; n = 25), and sling-only surgery (group C; n = 21).

Effective alleviation of depressive and anxious symptoms and sleep disorders in benzodiazepine-dependent patients through repetitive transcranial magnetic stimulation.

Benzodiazepine (BZD) dependence poses a significant challenge in mental health, prompting the exploration of treatments like repetitive transcranial magnetic stimulation (rTMS). This research aims to assess the impact of rTMS on alleviating symptoms of BZD dependence. A randomized control trial was employed to study 40 BZD-dependent inpatients.

Association between composite dietary antioxidant index and hyperlipidemia: a cross-sectional study from NHANES (2005-2020).

The association between the composite dietary antioxidant index (CDAI) and hyperlipidemia remains unclear. Therefore, this study aimed to investigate the relationship between CDAI and hyperlipidemia. The data used in this study were obtained from the National Health and Nutrition Examination Survey (NHANES) dataset spanning from 2005 to 2020.

Ultra-high Performance Thermochromic Polymers via a Solid-solid Phase Transition Mechanism and Their Applications.

Thermochromic materials are substances that change color in response to temperature variations. Today, sustainability concerns are the main drivers of thermochromic research, with smart, energy-efficient windows being one of the primary applications. While vanadium oxides and leuco dyes are traditionally the main thermochromic materials, hydrogels operating based on change of solvation have risen as some of the most promising materials due to their high optical transparency and good solar modulating abilities.

Effectiveness of repetitive transcranial magnetic stimulation for insomnia disorder on fear memory extinction: study protocol for a randomised controlled trial.

Background: Fear memory extinction is closely related to insomnia. Repetitive transcranial magnetic stimulation (rTMS) is safe and effective for treating insomnia disorder (ID), and it has been shown to be an efficient method for modulating fear extinction. However, whether rTMS can improve fear extinction memory in ID patients remains to be studied.

Correction: Thermoelectric nanowires for dense 3D printed architectures.

Correction for 'Thermoelectric nanowires for dense 3D printed architectures' by Danwei Zhang , , 2024, , 847-854, https://doi.org/10.1039/D3MH01646C.

High-definition transcranial direct current stimulation (HD-tDCS) in major depressive disorder with anxious distress-a study protocol for a double-blinded randomized sham-controlled trial.

Background: Comorbid anxiety disorders and anxious distress are highly prevalent among individuals with major depressive disorder (MDD). The presence of the DSM-5 anxious distress specifier (ADS) has been associated with worse treatment outcomes and chronic disease course. Few studies have evaluated the therapeutic effects of High-definition transcranial direct current stimulation (HD-tDCS) on depressive and anxiety symptoms among MDD patients with ADS.

Synergistic Combination of SbSiTe Additives for Enhanced Average ZT and Single-Leg Device Efficiency of BiSbTe-based Composites.

Thermoelectric materials are highly promising for waste heat harvesting. Although thermoelectric materials research has expanded over the years, bismuth telluride-based alloys are still the best for near-room-temperature applications. In this work, a ≈38% enhancement of the average ZT (300-473 K) to 1.

Association of carotid duplex ultrasonography screening with stroke and mortality among patients undergoing coronary artery bypass grafting.

Objective: Selection criteria for carotid duplex ultrasonography screening (DUS) before coronary artery bypass grafting (CABG) is primarily based on limited observational analysis, and the risks associated with carotid artery stenosis (CAS) detected by this approach to preoperative DUS are uncertain. This study aimed to determine the association of carotid DUS with stroke and mortality among patients undergoing CABG.

Methods: Adult patients with coronary artery disease who underwent isolated CABG or CABG with concomitant valvular or congenital procedure were identified.