Temperature dependence of optical parameters of a single crystal MnBOCl in the THz frequency range.

The dependence of optical properties of crystal on different temperatures within the terahertz frequency band has been investigated. By employing terahertz time-domain spectroscopy, the refractive index, absorption coefficient, and dielectric constant of the crystal were obtained. Results indicate that within the frequency range from 0.

Gene-Inherited [Se] Dimers in a Reactive Salt Flux: Synthesis of a Quasi-One-Dimensional NbSe Superconductor.

Transition metal dichalcogenides (TMDs) have attracted much attention due to their excellent properties in many fields. The existing thermodynamically stable TMDs are almost two-dimensional or three-dimensional in structure; therefore, the synthesis of new kinetic stable TMDs with lower dimensions is of great significance in materials science and chemistry. Here, we demonstrated the synthesis of a new type of NbSe with one-dimensional (1D) Nb[Se] chains by using KSe with low melting points as the reactive salt fluxes.

Biological functions and molecular mechanisms of circHIPK3 in digestive system tumors.

Digestive system tumors are the most common tumors worldwide with high mortality rates. Circular homeodomain-interacting protein kinase 3 (circHIPK3) is a highly abundant and stable circular RNA and have garnered significant attention in the field of cancer research. This review systematically explores potential of circHIPK3 as a clinical biomarker, clinical significance in pharmacotherapy, and molecular mechanisms that regulate biological functions such as cell proliferation, survival, migration, invasion, epithelial-mesenchymal transition, metabolism and angiogenesis in digestive system tumors.

Centimeter-size achromatic metalens in long-wave infrared.

Metalens has shown its significantly ultra-light and ultra-thin features. However, large-aperture achromatic metalens is constrained by both maximum dispersion range and computational memory. Here, we propose a fully device optimizing framework that engineers phase dispersion and amplitude transmittance to create centimeter-size achromatic metalens operating in long-wave infrared regime (8-12 μm).

Topochemical synthesis of anion-intercalated transition metal dichalcogenide superconductor SWS.

We have successfully synthesized bulk single crystals of SWS using a topochemical method, confirming the successful intercalation of sulfur into the interlayer space of M-WS, which induces hole doping. The material exhibits superconductivity with a transition temperature of 6.5 K, making it the first anion-intercalated/hole-doped TMD material.

MOF-Derived Nitrogen-Rich Hollow Nanocages as a Sulfur Carrier for High-Voltage Aluminum Sulfur Batteries.

Aluminum-sulfur batteries (ASBs) are emerging as promising energy storage systems due to their safety, low cost, and high theoretical capacity. However, it remains a challenge to overcome voltage hysteresis and short cycle life in the sulfur/AlS conversion reaction, which hinders the development of ASBs. Here, we studied a high-voltage ASB system based on sulfur oxidation in an AlCl/urea electrolyte.

[Orthopedic robot-assisted endoscopic transforaminal lumbar interbody fusion for lumbar disc herniation with lumbar instability].

Objective: To explore the safety and effectiveness of the robot-assisted system for transforaminal percutaneous endoscopic in the treatment of lumbar disc herniation with lumbar instability.

Methods: From October 2021 to March 2023, 26 patients with single-segment lumbar disc herniation and lumbar spinal instability were treated with robot-assisted system for transforaminal percutaneous endoscopic. The operation time, intraoperative blood loss, incision length, postoperative drainage volume, postoperative ambulation activity time, postoperative hospitalization time were record.

Strategies to enhance the therapeutic efficacy of anti-PD-1 antibody, anti-PD-L1 antibody and anti-CTLA-4 antibody in cancer therapy.

Although immune checkpoint inhibitors (anti-PD-1 antibody, anti-PD-L1 antibody, and anti-CTLA-4 antibody) have displayed considerable success in the treatment of malignant tumors, the therapeutic effect is still unsatisfactory for a portion of patients. Therefore, it is imperative to develop strategies to enhance the effect of these ICIs. Increasing evidence strongly suggests that the key to this issue is to transform the tumor immune microenvironment from a state of no or low immune infiltration to a state of high immune infiltration and enhance the tumor cell-killing effect of T cells.

High anisotropy in electrical and thermal conductivity through the design of aerogel-like superlattice (NaOH)NbSe.

Interlayer decoupling plays an essential role in realizing unprecedented properties in atomically thin materials, but it remains relatively unexplored in the bulk. It is unclear how to realize a large crystal that behaves as its monolayer counterpart by artificial manipulation. Here, we construct a superlattice consisting of alternating layers of NbSe and highly porous hydroxide, as a proof of principle for realizing interlayer decoupling in bulk materials.

Satellite Interference Source Direction of Arrival (DOA) Estimation Based on Frequency Domain Covariance Matrix Reconstruction.

Direction of arrival (DOA) estimation is an effective method for detecting various active interference signals during the satellite navigation process. It can be utilized for both interference detection and anti-interference applications. This paper proposes a DOA estimation algorithm for satellite interference sources based on frequency domain covariance matrix reconstruction (FDCMR) to address various types of active interference that may occur in the satellite navigation positioning process.

Preoperative prediction and risk assessment of microvascular invasion in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is one of the most common and highly lethal tumors worldwide. Microvascular invasion (MVI) is a significant risk factor for recurrence and poor prognosis after surgical resection for HCC patients. Accurately predicting the status of MVI preoperatively is critical for clinicians to select treatment modalities and improve overall survival.

Ferromagnetism induced by in-plane strain in a bulk VS-based superlattice: (LiOH)VS.

Transition metal dichalcogenides (TMDs) have attracted intensive research interest due to their diverse properties. However, ferromagnetism is not observed in layered TMDs, except for monolayer VSe. In this study, we report the synthesis of a bulk ferromagnetic material (LiOH)VS based on topochemical reactions.

Synergistic Transition-Metal Selenide Heterostructure as a High-Performance Cathode for Rechargeable Aluminum Batteries.

We synthesize and characterize a rechargeable aluminum battery cathode material composed of heterostructured CoSe/ZnSe embedded in a hollow carbon matrix. This heterostructure is synthesized from a metal-organic framework composite, in which ZIF-8 is grown on the surface of ZIF-67 cube. Both experimental and theoretical studies indicate that the internal electric field across the heterostructure interface between CoSe and ZnSe promotes the fast transport of electron and Al-ion diffusion.

Manganese-coordinated mRNA vaccines with enhanced mRNA expression and immunogenicity induce robust immune responses against SARS-CoV-2 variants.

It is urgent to develop more effective mRNA vaccines against the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants owing to the immune escape. Here, we constructed a novel mRNA delivery system [IC8/Mn lipid nanoparticles (IC8/Mn LNPs)]with high immunogenicity, via introducing a stimulator of interferon genes (STING) agonist [manganese (Mn)] based on a newly synthesized ionizable lipid (IC8). It was found that Mn can not only promote maturation of antigen-presenting cells via activating STING pathway but also improve mRNA expression by facilitating lysosomal escape for the first time.

Revealing the effect of grain boundary segregation on Li ion transport in polycrystalline anti-perovskite LiClO: a phase field study.

Lithium ion transport in a polycrystalline solid-state electrolyte (SSE) is directly linked to the properties of lithium ion batteries. Grain boundaries (GBs), as essential defects in SSE, have been found to play a significant role in the overall kinetics of lithium ion transport, however, the mechanism is not well understood due to the complex role of GBs. The GBs could affect the overall kinetics of ionic transport in the SSEs in two ways: (i) Li/Na diffusivities inside the GBs could be different from those in the bulk, and (ii) point defect segregation at the GBs.

Catalytic asymmetric Povarov reaction of isatin-derived 2-azadienes with 3-vinylindoles.

The first catalytic asymmetric Povarov reaction of isatin-derived 2-azadienes with 3-vinylindoles was established in the presence of chiral phosphoric acid, which tolerates a wide range of substrates with generally excellent diastereoselectivity and good enantioselectivity (up to >95 : 5 dr, 89 : 11 er). This approach will greatly enrich the chemistry of the catalytic asymmetric Povarov reaction, in particular ketone-involved transformations. Furthermore, this protocol represents the first diastereo- and enantio-selective construction of a spiro[indolin-3,2'-quinoline] framework bearing an indole moiety.

Simultaneous determination of furfural, acetic acid, and 5-hydroxymethylfurfural in corncob hydrolysates using liquid chromatography with ultraviolet detection.

A single-laboratory validation study was conducted using HPLC for detecting and quantifying acetic acid, furfural, and 5-hydroxymethylfurfural (HMF) in corncob hydrolysates. A pretreatment procedure using dilute sulfuric acid was optimized for corncob hydrolysis. The final hydrolysates were analyzed by HPLC using a C18 RP column with aqueous 0.

Damage to mtDNA in liver injury of patients with extrahepatic cholestasis: the protective effects of mitochondrial transcription factor A.

Oxidative stress and mitochondrial dysfunction are involved in the pathogenesis of chronic liver cholestasis. Mitochondrial DNA (mtDNA) is highly susceptible to oxidative stress and mtDNA damage leads to mitochondrial dysfunction. This study aimed to investigate the mtDNA alterations that occurred during liver injury in patients with extrahepatic cholestasis.

Investigations of different chemiluminescent peaks in H2O2-SCN(-)-Cu(2+)-OH(-)-luminol flow system.

In the H2O2-SCN(-) -Cu(2+)-OH(-)-luminol oscillatory system of chemiluminescence, the effects of the ingredient concentrations, temperature, flow rate and complexing agent on the oscillatory dynamics were investigated in a continuous-flow stirred tank reactor (CSTR). The dynamical structure of two peaks during a period was discussed in detail. By addition of EDTA to the oscillating system, the peak I height decreased sharply while the peak II height was little affected, and the period kept constant.

[The interaction of berberine and human serum albumin].

The interaction of berberine and Human Serum Albumin (HSA) has been studied by fluorescence and UV-Vis absorption spectroscopy. With fluorescence quenching method, the binding constant K was found to be 1.168 x 10(5) L x mol(-1) and the number of binding site n was 5.

Thermodynamic study on the effects of beta-cyclodextrin inclusion with berberine.

The fluorescence enhancement of berberine (Berb) as a result of complex with beta-cyclodextrin (beta-CD) is investigated. The association constants of alpha-CD and beta-CD with Berb are 60 and 137 M(-1) at 20 degrees C in pH 7.20 aqueous solution.