97 results match your criteria: "Yong in University[Affiliation]"

Article Synopsis
  • Kisspeptins, derived from the KISS1 gene, are crucial regulators of GnRH neurons through their interaction with the GPR54 receptor, playing a key role in reproductive hormone signaling.
  • The study investigates the presence of kisspeptin in Syrian hamster testes using RT-PCR and immunohistochemistry techniques, revealing detectable levels of kisspeptin in Leydig cells and some germ cells.
  • These findings contribute to understanding the function of kisspeptin in hamster testes and its potential implications for reproductive physiology, particularly regarding the impact of photoperiod on gonadal regression.
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Weakening muscle strength around the knee tends to render it vulnerable to aging-related damage. This study aimed to examine the association between knee flexor muscle strength and its cross-sectional area (CSA). We also evaluated aging-related changes in flexor muscle strength and CSA.

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Purpose: This study aimed to investigate the association between physical performance and subjective wellbeing among Chinese older adults.

Methods: Data on the Chinese population were gathered from the Study on Global Aging and Adult Health Survey (SAGE). This survey used a stratified multistage cluster sample design based on geographical location and economic status.

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C1q and TNF-related 1 (C1QTNF1/CTRP1) is an adiponectin-associated protein belonging to the C1q/TNF-related protein family. Recent studies have shown that the C1q and TNF-related protein (CTRP) family is involved in cancer progression; however, the specific role of CTRP1 in tumor progression has not yet been elucidated. To examine the role of CTRP1 in tumor progression, we generated CTRP1 knockout A549 and HCT116 cell lines, which reduced the expression levels of nuclear factor (NF)-κB-dependent and metastasis-promoting transcripts.

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We investigated the influence of the menstrual cycle (MC) on leukocyte response after exercise-induced muscle damage (EIMD). During the early follicular (E-FP, = 12) or mid-luteal phase (M-LP, = 12), 24 untrained females with eumenorrhea performed 60 eccentric exercises using nondominant arms. Blood samples were collected at pre- and 4, 48, and 96 h postexercise to analyze estradiol and progesterone concentrations, leukocyte count and fractionation, and creatine kinase (CK) activity.

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Expressions of Gonadotropin Subunit Genes in the Reproductively Inactive Golden Hamsters.

Dev Reprod

June 2022

Dept. of Life Science, College of Health and Welfare Sciences, Yong-In University, Yongin 17092, Korea.

Photoperiod has well been established to regulate testicular activities in golden hamsters. These animals breed actively around summer but become infertile in winter. In males, testicles are full of multistep germ cells including spermatozoa in summer.

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Purpose: The purposes of the current study were to develop a questionnaire to measure parental physical activity (PA) support in parents of children with disabilities and to examine factors associated with parental PA support.

Materials And Methods: A questionnaire measuring parental PA support in parents of children with disabilities (PPSQ for PCD), consisting of three constructs (encouragement, co-PA, and logistic support) with 19 items, was initially developed and evaluated by the Confirmatory Factor Analysis. Three independent multiple regression analyses were conducted to examine associations between the three constructs and parental PA orientation variables.

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Purpose: The present study attempted to explore the effects of different tempos of piano music on heart rate and autonomous nervous system during the recovery period after high-intensity exercise. In addition, the study analyzed the influence of different tempos on the recovery period of athletes to devise methods for accelerating fatigue recovery through piano music.

Method: A total of 57 college students majoring in physical education were selected as experimental subjects and were divided into three groups, namely Lento group (n = 20), Moderato group (n = 20), and Allegretto group (n = 20; only 17 students completed the experiment).

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In sports, because the movement of the human body is composed of the movements of the human limbs, and the complex and changeable movements of the human limbs lead to various and complicated movement modes of the entire human body, it is not easy to accurately track the human body movement. The recognition of human characteristic behavior belongs to a higher level computer vision topic, which is used to understand and describe the characteristic behavior of people, and there are also many research difficulties. Because the radial basis fuzzy neural network has the characteristics of parallel processing, nonlinearity, fault tolerance, self-adaptation, and self-learning, it has the advantage of high recognition efficiency when it is applied to the recognition of intersecting features and incomplete features.

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Background: Reducing the compensatory mechanism by restraining unnecessary trunk movements may help enhance the effectiveness of robot-assisted therapy.

Objective: This study aimed to investigate the effects of robot-assisted therapy in combination with trunk restraint on upper extremity function and on daily activities in patients with acute stroke (≤ 30days of onset).

Methods: Thirty-six acute stroke patients were randomly assigned to an experimental (n=18) or control (n=18) group.

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A Chronic-Low-Dose Exposing of DEHP with OECD TG 443 Altered the Histological Characteristics and Steroidogeic Gene Expression of Adrenal Gland in Female Mice.

Dev Reprod

December 2021

Division of Developmental Biology and Physiology, Center for Development and Program Research, Department of Biotechnology, Institute of Basic Sciences, Sungshin University, Seoul 02844, Korea.

Article Synopsis
  • Phthalates, specifically di-(2-ethylhexyl) phthalate (DEHP), are recognized as endocrine disruptors, commonly found in industrial products, leading to significant exposure risks for adults.* -
  • In a study with mature female mice, DEHP in drinking water was linked to an increase in adrenal gland wet weight and changes in the morphology of the zona fasciculata, indicating effects on the adrenal cortex.* -
  • While some steroidogenic gene expressions were altered due to DEHP exposure, such as decreased levels of DAX1, there were no significant differences in the overall morphology or extracellular matrix arrangement in the adrenal gland compared to control groups.*
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Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer.

Biomol Ther (Seoul)

September 2021

BK21 FOUR Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 10326, Republic of Korea.

The imprinted tumour suppressor NOEY2 is downregulated in various cancer types, including ovarian cancers. Recent data suggest that NOEY2 plays an essential role in regulating the cell cycle, angiogenesis and autophagy in tumorigenesis. However, its detailed molecular function and mechanisms in ovarian tumours remain unclear.

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In this paper, a deep confidence neural network algorithm is used to design and deeply analyze the risk warning model for stadium operation. Many factors, such as video shooting angle, background brightness, diversity of features, and the relationship between human behaviors, make feature attribute-based behavior detection a focus of researchers' attention. To address these factors, researchers have proposed a method to extract human behavior skeleton and optical flow feature information from videos.

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Objectives: The aim of this study was to provide baseline data for the assessment of exposure to indium and to prevent adverse health effects among workers engaged in the electronics and related industries in Republic of Korea.

Methods: Total (n = 369) and respirable (n = 384) indium concentrations were monitored using personal air sampling in workers at the following 19 workplaces: six sputtering target manufacturing companies, four manufacturing companies of panel displays, two companies engaged in cleaning of sputtering components, two companies dedicated to the cleaning of sputtering target, and five indium recycling companies.

Results: The level of exposure to total indium ranged from 0.

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Article Synopsis
  • * During this inactive phase, the blood-testis barrier (BTB) loses its integrity, causing developing germ cells to either be engulfed by Sertoli cells or slough off, leading to the absence of sperm in most epididymis regions.
  • * Key genes responsible for tight junctions in the BTB (like claudin-11 and occludin) are present in active testes but not in inactive ones, indicating that structural disorganization of the BTB is linked to testicular regression and the removal of germ
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This present study aims to investigate factors that impact behavioural intention of university students on e-learning use during the COVID-19 pandemic. An online questionnaire was utilised to gather data from 109 students enrolled in one of the universities in Indonesia. The Technology Acceptance Model (TAM) was the primary framework employed for analysis, in which system quality and e-learning experience were included as external constructs to seek out a much better model to improve the understanding of students' intention to adopt e-learning.

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Utilization of Complementary and Alternative Medicine among Korean Elite Athletes: Current Status and Future Implications.

Evid Based Complement Alternat Med

February 2021

Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.

The objective of the study was to explore the status of usage of complementary and alternative medicine (CAM) among Korean elite athletes. A survey was emailed to all Korean national sports federations recognized by the International Olympic Committee and the Olympic Council of Asia. A total of 705 Korean elite athletes participated in this study.

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The current study investigated what influences college students' behavioral intention and behavior towards sports gambling using the theory of planned behavior (TPB) as a theoretical framework. The study also explored the moderation effect of problem gambling severity in the relationships between TPB determinants, behavioral intention, and sports gambling behavior. Data were collected from 334 college students from four different universities in the U.

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Article Synopsis
  • Melatonin has been shown to cause testicular regression in seasonal breeding animals, particularly in male Syrian hamsters when injected in the afternoon.
  • A study examined the effects of different dosages of melatonin given daily via gavage on hamsters kept in long and short photoperiods over 8 weeks.
  • Results indicated that higher doses of melatonin led to significant testicular shrinkage compared to controls, with low doses having no adverse effect, similar to the large testes seen in the long photoperiod control group.
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YY1 and CP2c in Unidirectional Spermatogenesis and Stemness.

Dev Reprod

December 2020

Department of Life Science and Research Institute for Natural Sciences, College of Natural Sciences, Hanyang University, Seoul 04763, Korea.

Article Synopsis
  • Spermatogonial stem cells (SSCs) have unique characteristics that allow them to develop into gametes, undergoing significant changes in gene expression during spermatogenesis.
  • The process includes phases like gene repression and chromatin modifications, ultimately leading to the formation of fertilization-ready spermatozoa.
  • Recent research highlights the roles of transcription factors YY1 and CP2c in regulating spermatogenesis and stemness, providing insights into their interactions during specific stages of sperm development.
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Article Synopsis
  • This study investigates how following 24-hour movement guidelines (which include physical activity, sedentary behavior, and sleep) impacts body fat percentage in Asian adolescents across eight major cities.
  • Researchers collected data from over 12,000 adolescents, finding that levels of compliance with these guidelines varied significantly from city to city.
  • The results indicate that meeting more of the movement guidelines is associated with lower body fat percentages, suggesting that adherence to these guidelines could support healthier body weight in young people.
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Article Synopsis
  • - The study built on previous findings indicating that low-dose nonylphenol (NP) exposure negatively impacts the reproductive health of female mice, specifically looking at its effects on their reproductive organs.
  • - Mice were exposed to NP from before mating until their offspring were 33 days old, with significant findings such as early vaginal opening and differences in tissue weights related to NP exposure.
  • - Pathohistological analysis revealed changes in ovarian follicle numbers and uterine structure, suggesting that NP exposure leads to early puberty and reproductive abnormalities, prompting the need for further research to clarify NP's effects and mitigate risks.
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IRF-1 Inhibits Angiogenic Activity of HPV16 E6 Oncoprotein in Cervical Cancer.

Int J Mol Sci

October 2020

Phamaceutical Biochemistry, College of Pharmacy and Integrated Research Institute for Drug, Dongguk University, Goyang 100-715, Korea.

HPV16 E6 oncoprotein is a member of the human papillomavirus (HPV) family that contributes to enhanced cellular proliferation and risk of cervical cancer progression via viral infection. In this study, interferon regulatory factor-1 (IRF-1) regulates cell growth inhibition and transcription factors in immune response, and acts as an HPV16 E6-binding cellular molecule. Over-expression of HPV16 E6 elevated cell growth by attenuating IRF-1-induced apoptosis and repressing p21 and p53 expression, but activating cyclin D1 and nuclear factor kappa B (NF-κB) expression.

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The purpose of the present study was to investigate the effects of cold exposure discontinuation on local cold tolerance of older retired female haenyeos in Korea. A total of 30 older women participated in this study: older retired haenyeos (89 ± 4 y in age, N = 10), active haenyeos (current divers) (75 ± 4 y, N = 10), and age-matched non-divers (75 ± 6 y, N = 10). Our criterion for local cold tolerance was cold-induced vasodilation (CIVD) of the finger.

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Background: Trunk control ability has been identified as an important early predictor of functional recovery after stroke.

Objective: Our study aimed to investigate the effects of three-dimensional active trunk training exercise on trunk control ability, trunk muscle strength, and balance ability in sub-acute stroke patients.

Methods: Twenty-four sub-acute stroke patients were randomly assigned to an experimental (n= 12) or control (n= 12) group.

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