A Review of Acupuncture for the Treatment of Dry Eye Syndrome: Mechanisms, Efficacy, and Clinical Implications.

Dry eye disease (DED) is a prevalent ocular condition characterized by discomfort and vision impairment in affected individuals. This review discusses various etiologies of DED, including autoimmune, drug-induced, and mechanical factors, each with distinct underlying causes. Acupuncture, a traditional therapeutic modality, has garnered increasing attention in recent years as a potential complementary treatment for DED.

Psychological resilience in deaf or hard-of-hearing students and associated factors: A cross-sectional study.

Mental health in deaf and hard-of-hearing (D/HH) students is a severe issue. Psychological resilience is a well-established protective factor of mental health. We aimed to examine the current situation of psychological resilience in D/HH students and identify the associated factors.

The role of RANBP1 in regulating MiRNA expression and apoptosis in breast cancer cells.

Background: Breast cancer poses a huge health threat in China. Emerging evidence has indicated that RANBP1 is associated with poor prognosis of breast cancer and has been shown to influence miRNA expression in colorectal cancer. But its role in breast cancer remains unclear.

Comparative differences in job preferences among doctors in different levels of public hospitals in Henan, China: a discrete choice experiment.

Background: Doctor turnover is a significant challenge faced by hospitals worldwide, particularly in public hospitals in China. By understanding how job attributes influence job preferences among doctors, effective and targeted policies can be designed to attract doctors to key positions or organizations, providing insights for evidence-based workforce interventions.

Objectives: The aim of our study is to examine the difference of job preferences of doctors in different hospitals levels using DCE.

Notch2 improves granulosa cell functions in premature ovarian failure by activating the Wnt2/β-catenin pathway.

Background: Notch2 and Wnt2/β-catenin pathway improve granulosa cell (GC) functions, and there are interactions between Notch and Wnt/β-catenin in some cells. We aimed to investigate whether Notch2 improves GC functions in premature ovarian failure (POF) by activating the Wnt2/β-catenin pathway.

Methods: Notch2 expression was interfered in mice or KGN cells, then, mice were treated with cyclophosphamide and busulfan intraperitoneally, and KGN cells were exposed to cyclophosphamide to establish POF models.

Atypical bilateral papilledema during the puerperium: a case report.

Background: To analyze a case of atypical bilateral papilledema in a puerperium woman, and to explore the pathogenic mechanism of pregnancy-related physiological changes, blood hypercoagulable state, immune abnormalities and abnormal structure of intracranial venous sinus, so as to provide reference for early diagnosis and intervention of similar cases.

Case Report: A 28-year-old woman, 3 days post-operative from a cesarean section, presented at the hospital with decreased vision in her right eye. An examination revealed bilateral papilledema.

Association between family functioning and academic burnout among vocational college nursing students: mediating role of academic self-efficacy.

Introduction: Academic burnout is not uncommon and interferes with the role shift from nursing students to qualified nurses, aggravating a shortage of workforce in global healthcare system. However, there is currently a lack of research examining the relationship between family functioning, academic self-efficacy, and academic burnout in nursing students. The purpose of this study is to examine the relationship among family functioning, academic self-efficacy, and academic burnout among nursing students.

Metabolomics combined with metagenomics analysis reveals the potential mechanism of Zhejiang psyllium polysaccharides against hyperuricemia in rats.

This study aimed to assess the anti-hyperuricemia efficacy of Zhejiang psyllium polysaccharides (ZPP) in rats and to explore its underlying mechanism. Hyperuricemia was induced by intragastric administration of potassium oxonate, hypoxanthine, and adenine. The serum levels of uric acid (UA), creatinine (Cr), and blood urea nitrogen (BUN) were measured, and kidney pathology was examined.

Negative workplace gossip and turnover intention among kindergarten teachers: psychological safety as a mediator and organizational identification as a moderator.

Purpose: Empirical evidence examining factors influencing turnover intention among early childhood educators remains scarce, especially research on negative workplace gossip as the influencing factor. To address these shortcomings, this study empirically analyzed whether and how negative workplace gossip, psychological safety, and organizational identification affect kindergarten teachers' turnover intention based on the Chinese cultural background.

Methods: A cross-sectional research design was adopted.

Endoscopic surgery combined with titanium mesh for infantile solitary orbital myofibroma: a case report.

Background: To report the clinical features, misdiagnosis process and minimally invasive treatment experience of endoscopy combined with titanium mesh in a 3-year-old infant with isolated orbital myofibroma, and to discuss the key points of differential diagnosis and treatment strategy.

Case Report: A 3-year-old male patient presented with progressive swelling of the left lower eyelid for 1 month, without eye redness, eye pain, diplopia, or ocular motility disturbance. There was no significant family history or past medical history.

Live bacteria found in gastric cancer tumor tissue.

Background: Most research on gastric cancer and microorganisms has focused on as a causative agent and on the relationship between the microbiota and gastric cancer. There is no direct evidence of bacteria in gastric cancer tissues or their relationship with gastric cancer.

Methods: Gastric cancer tissue samples were collected, and the bacteria within tumor tissues were observed by transmission electron microscopy.

Long and short term fault prediction using the VToMe-BiGRU algorithm for electric drive systems.

With the rapid development of new energy vehicle technology, electric drive systems play a crucial role in the modern automotive industry. Ensuring the efficient and stable operation as well as reliability of electric drive systems has become a critical task. In order to prevent serious faults in the short-term leading to potential accidents, this paper proposes an innovative approach for embedding the Token Merging (ToMe) algorithm into the Vision Transformer (ViT), called the VToMe algorithm and combining it with the Bidirectional Gated Recurrent Unit (BiGRU) network to form the VToMe-BiGRU architecture for electric drive system fault prediction.

A global prevalence of turnover intention among doctors: a systematic review and meta-analysis.

Turnover intention (TI) among doctors is a critical issue in healthcare systems worldwide, as it can lead to workforce shortages, increased workload for remaining staff, and negatively impact patient care. This review aimed to explore the prevalence and determinants of TI among doctors, providing a comprehensive understanding of the factors influencing their turnover intentions. A systematic review was conducted using four electronic databases: PubMed, Web of Science, Medline, and Scopus.

Chloroquine inhibits salinomycin-induced autophagy for collaborative anticancer effect in breast cancer.

Introduction: Breast cancer (BC) presents significant morbidity and mortality challenges. Autophagy plays a contradictory role in BC. The chemotherapeutic agent salinomycin exhibits anticancer effects, but its effectiveness is limited by over-activation of autophagy.

Global, regional and national burden of depressive disorders in adolescents and young adults, 1990-2021: systematic analysis of the global burden of disease study 2021.

Background: To promote evidence-based policymaking, this research attempts to investigate global trends in depressive disorders among individuals aged 15-39 from 1990 to 2021, determine risk factors, and forecast the next trends from 2022 to 2050.

Methods: Data from the Global Burden of Disease (GBD) 2021 database were analyzed to look at the global, national, and regional burden of depressive disorders among individuals aged 15-39 from 1990 to 2021. Incidence rates, disability-adjusted life years (DALYs), and contributions of various risk factors to DALYs were also examined in this research.

Validation of the Chinese Patient Participation Scale (PPS-C) in Internal Medicine Patient: A Psychometric Study.

Objective: To translate the Patient Participation Scale (PPS) into Chinese and evaluate its psychometric properties among internal medicine patients in a tertiary hospital in China, providing a reliable tool for enhancing patient participation in healthcare decisions.

Background: Patient participation is critical for patient-centered care, widely proven to enhance healthcare quality and improve health outcomes. While China increasingly recognizes the importance of patient participation in clinical decision-making, evidence-based interventions remain limited, partly due to the lack of validated measurement tools.

Thermal stress and thermal deformation of a nozzle flowmeter with different weld structures.

Nozzle flow meters are widely used in the field of measuring high temperature media. In order to investigate the effect of nozzle flowmeter weld structure on thermal stress and thermal deformation, 10 different weld structures were designed in terms of the distance between the weld metal and the eight-groove nozzle, the width of the bottom of the weld metal, the taper angle of the weld metal, and the opening of the taper angle of the weld metal. The thermal stress and thermal deformation characteristics of the solid domain of the nozzle flowmeter are also calculated numerically for a high temperature case.

Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway.

Background: Bronchopulmonary dysplasia (BPD) is a common respiratory disease in premature infants. Nesfatin-1 is considered for the treatment of BPD. This study aimed to explore the anti-inflammatory effect of nesfatin-1 in the treatment of BPD.

Mediating Effects of Health Literacy, Self-Efficacy, and Social Support on the Relationship Between Disease Knowledge and Patient Participation Behavior Among Chronic Ill Patients: A Cross-Sectional Study Based on the Capability-Opportunity-Motivation and Behavior (COM-B) Model.

Purpose: Patient participation is essential for improving patient safety and quality of care. It mainly refers to patients participating in their own healthcare through various ways, such as searching information on treatment options, engaging in decision-making, and communicating with healthcare professionals. This study aimed to investigate the relationships between disease knowledge, health literacy, self-efficacy, social support, and patient participation behavior in chronic ill patients based on the Capability-Opportunity-Motivation and Behavior (COM-B) model.

Perception of fall risk in hospitalized patients and associated factors: A cross-sectional study and path analysis.

Background And Purposes: Evidence regarding patients' perception of fall risk is scarce. This study aimed to investigate the current situation and the associated factors of patients' perception of fall risk, explore the mechanisms, and identify the subgroup of patients who may be at greater risk of having an erroneous perception.

Methods: Participants were recruited from three wards of two tertiary general hospitals in China.

Developing a decision support system for sustainable urban planning using machine learning-based scenario modeling.

Urbanization is rapidly transforming cities, posing intricate issues for sustainable urban development. Conventional urban planning techniques frequently encounter difficulties in incorporating several variables, including environmental, social, and economic issues. This research presents an innovative decision support system (DSS) aimed at tackling these difficulties through the application of machine learning and fuzzy decision-making methodologies.

Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review.

Background: Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and extremely poor prognosis. There is first report on hepatic angiosarcoma accompanied by eosinophilia.

Case Presentation: A woman with a chief complaint of poor appetite for about 3 months presented to a local hospital with a liver mass.

Posture Control of Hydraulic Flexible Second-Order Manipulators Based on Adaptive Integral Terminal Variable-Structure Predictive Method.

As operational scenarios become more complex and task demands intensify, the requirements for the intelligence and automation of manipulators in industry are increasing. This work investigates the challenge of posture tracking control for hydraulic flexible manipulators by proposing a discrete-time integral terminal sliding mode predictive control (DITSMPC) method. First, the proposed method develops a second-order dynamic model of the manipulator using the Lagrangian dynamic strategy.

High-temperature requirement serine protease A2 inhibitor UCF-101 ameliorates damaged neurons in traumatic brain-injured rats by the AMPK/NF-κB pathway.

Traumatic brain injury (TBI) leads to permanent damage, including neurological deficits, cognitive deficits, and cerebral edema. The specific inhibitor of serine protease Omi/high-temperature requirement A2 (Omi/HtrA2), UCF-101, exerts neuroprotective effects, but its role in TBI remains unclear. Eighty-four male Sprague Dawley rats were randomized to control, TBI, UCF-101 of low dose (1.

Influence of drilling incidence angle on the drilling force distribution of pneumatic impactor.

Pneumatic impactor is widely used in the drilling process of various medium and high hard rocks with poor drill ability. Currently, there is relatively little analysis on the impact of the inclination of the rock surface during the drilling process on the drilling efficiency and excavation capability of pneumatic impactors. Based on the dynamic theory of impact drilling and finite element method (FEM), the constitutive model of HJC criterion and INVENTOR 3D mechanical structure design software, a 3D numerical analysis system of piston-bit head-rock during pneumatic impactor drilling is established by ANSYS LS-DYNA, a nonlinear dynamic analysis software.