Frequency of laughter and depression onset among older adults: A 6-year longitudinal study from the Japan Gerontological Evaluation Study.

Background: Laughter has been associated with mental and physical health benefits, but longitudinal evidence on whether laughter in daily life protects against depression remain limited. This study aimed to examine whether the frequency of laughter in daily life is associated with the risk of depression onset among older adults.

Methods: We analyzed data from 32,666 adults aged ≥65 years participating in the Japan Gerontological Evaluation Study, a three-wave cohort conducted over six-years.

Socioeconomic Inequalities in Oral Frailty Among Older Adults: A Causal Mediation Analysis on the Role of Prevention From Tooth Loss.

Background: Although social inequalities in oral health have been suggested, the link between socioeconomic status (SES) and oral frailty (OF) remains unclear. We aimed to investigate the inequalities in OF according to SES and the extent to which inequalities are mitigated by preventing tooth loss.

Methods: We used cross-sectional data from 21 542 functionally independent participants aged ≥ 65 (48.

Chewing difficulty, swallowing problems, xerostomia and cause-specific mortality among older adults: A 7-year follow-up JAGES cohort study.

Aim: Although various poor oral health conditions have been reported to be associated with an increased all-cause mortality risk, a comprehensive investigation of the causes of death is limited. This study aimed to investigate the association between poor oral function and mortality due to various causes in older adults.

Methods: This 7-year follow-up cohort study used data from the Japan Gerontological Evaluation Study.

Perceived indoor thermal environment and depressive symptoms among older adults in the Japan Gerontological Evaluation Study.

Depression is a major global health problem and presents a significant health burden. Although abnormal indoor temperatures are known to be associated with adverse health effects, their link to depression is unclear, especially regarding indoor heat. This study aimed to examine the association between perceived indoor cold or heat and depressive symptoms among Japanese older adults.

Oral health and happiness after 3-years with causal mediation of oral functions.

Objectives: The longitudinal association between oral health and self-reported happiness among older population and its mediating pathways were unknown. This study investigated the aforementioned association and the role of three oral functions (having difficulty in speaking, problems in smiling and difficulty in chewing) as causal mediating pathways.

Methods: In this 3-year cohort study, the 2016-2019 panel data on 65 years or older independent participants from Japan Gerontological Evaluation Study (JAGES) was used (N = 53,863).

Oral Frailty as a Predictor for Weight Loss in Older Japanese: A Cohort Study.

Oral frailty is a key factor in maintaining nutritional status, yet its impact on weight loss remains unclear. This study aimed to (1) evaluate the longitudinal association between oral frailty and the onset of weight loss among independent older adults and (2) explore how oral frailty components contribute to this association. Data were sourced from 2016 to 2022 of the Japan Gerontological Evaluation Study (JAGES).

Association between infrequent denture cleaning and all-cause mortality risk among community-dwelling older adults: Findings from a six-year cohort study.

Statement Of Problem: Although dental prostheses provide important clinical benefits for individuals with tooth loss, removable dentures can also serve as reservoirs for pathogenic microorganisms. Although denture cleanliness has been associated with pneumonia risk among older adults in residential or hospital settings, its relationship with adverse health outcomes among community-dwelling older adults remains unclear.

Purpose: The purpose of this cohort study was to investigate the association between the frequency of denture cleaning and the risk of all-cause mortality among community-dwelling older adults.

Mechanical and Biological Properties of Nondecellularized Human Wharton's Jelly Matrix for Soft Tissue Graft Material: An In Vitro Study.

This study aims to determine the mechanical properties of hWJM through ultimate tensile strength (UTS) and elastic modulus tests, degradation, and porosity tests. Additionally, it evaluates the biological properties of hWJM by assessing growth factor secretion (fibroblast growth factor-2 [FGF-2] and vascular endothelial growth factor-A [VEGF-A]).For the mechanical tests, two groups were analyzed: group 1 was tested in a wet condition and group 2 in a dry condition.

Mechanical and biological properties of cellulose nanofibers as a dental biomaterial.

Background/purpose: Plant-derived cellulose nanofibers (CNF) have emerged as a promising material for biomedical applications due to their diverse and exceptional properties but application in dental research remains limited. This study aimed to use CNF as barrier membranes or scaffold materials applied in guided bone regeneration (GBR) and guided tissue regeneration (GTR).

Materials And Methods: Two different thicknesses of CNF were detected by surface morphology, roughness, hydrophilicity, mechanical properties, and degradability test, and compared with GC Membrane and Ti (titanium).

Removable partial denture, complete denture, and fixed partial denture use and health-related quality of life among older adults with tooth loss: A JAGES cross-sectional study.

Purpose: To investigate the association of removable partial denture (RPD)/complete denture (CD) and fixed partial denture (FPD) use with health-related quality of life (HRQoL), evaluated using the EuroQol 5-dimension, 5-level instrument (EQ-5D-5L) among older adults with tooth loss.

Methods: Cross-sectional data from the 2022 Japan Gerontological Evaluation Study. Participants were classified as RPD/CD users, FPD users, or nonusers.

Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells.

Elucidate the dicalcium phosphate dihydrate (DCPD)-coated-beta-tricalcium phosphate (β-TCP) porous granules osteoinductivity performance in adipose-derived mesenchymal stem cells (ADMSCs). β-TCP porous was made by adding the sodium chloride (NaCl) powders with the dry powder of DCPD and CaCO in the concentrations 40:60 (by wt%). Then, DCPD layer will be formed on porous β-TCP granules by immersing the granules in an acidic calcium phosphate solution.

Utilization of cellulose nanofiber in dental applications: A systematic review of in vitro evidence.

This systematic review aimed to determine how cellulose nanofiber (CNF) enhance the mechanical properties, biocompatibility, and functional versatility of dental materials, based on in vitro evidence. A systematic review protocol was developed according to PRISMA 2020. The literature search was conducted using MEDLINE/PubMed, Scopus, Web of Science, Scopus, and Embase for English-language publications with no date restrictions, yielding 180 publications.

Combined association of social isolation and loneliness with frailty onset among independent older adults: A JAGES cohort study.

Objectives: Social isolation and loneliness each have negatively affect various health outcomes. No studies have examined the combined association of social isolation and loneliness on frailty onset. This study aimed to investigate both the objective and subjective aspects of isolation by evaluating social isolation and loneliness and to determine their interaction effects on frailty onset.

Construction of a Ti implant-based responsive OPG release platform for enhanced osteoporotic bone regeneration programmed regulation of osteogenesis and bone resorption.

The potential for persistent and controllable delivery of osteoprotegerin (OPG) under osteoporotic conditions has become an essential property of bone implants to promote osseointegration and osteogenesis. Herein, a microenvironment-responsive surface coating for titanium (Ti) implants by immobilizing metal-organic frameworks (MOFs) loaded with OPG onto alkali heat-treated Ti surfaces gelatin (Gel) (AHT-MOF@OPG-GEL) was successfully fabricated. In a weakly acidic environment, MOF@OPG can achieve responsive degradation and slow release of zinc ions (Zn) and OPG, which not only inhibits osteoclast activity and osteoclastic biomarker expressions but also potentiates osteoblast proliferation and differentiation .

Behavior Puzzle: Nonpharmacological Behavior Management.

Unlabelled: A child's dental visit may often be associated with dental fear and anxiety (DFA). Children with DFA may exhibit dental behavior management problems (DBMPs), which mostly manifest as disruptive behavior. Children displaying disruptive behavior are often more challenging to treat, require more chairside time, and can result in a stressful appointment for the child, parent, and even the dentist.

Association of Number of Teeth Present With Nutrient Intake and Food Group Consumption.

Background: Several studies have examined the impact of tooth loss on nutrient intake, yielding mixed results.

Objectives: This cross-sectional study aimed to investigate the association among the number of teeth present, nutrient intake and food group consumption in Japanese adults with no history of the four major diseases (diabetes, cancer, heart disease and stroke).

Methods: Data were obtained from the baseline survey of the Japan Multi-Institutional Collaborative Cohort study conducted in the Shizuoka and Daiko areas.

Impact of posterior occlusal contact loss on cardiovascular disease using a Japanese claims database.

Cardiovascular disease (CVD) is a global health concern; however, its association with the posterior occlusal contact remains unexplored. This study investigated the association between posterior occlusal contact and CVD risk in a large Japanese cohort and examined whether the loss of posterior occlusal contact in individuals with at least 20 teeth was a distinct CVD risk factor. Using Japanese health insurance claims data from 1,209,997 adults aged ≥ 40 years without prior CVD history (April 2016-March 2022), participants were categorized using the Eichner classification to assess posterior occlusal contact.

Final shade and whiteness: impact of various ultra-thin CAD/CAM veneers and tooth-colored resin substrates.

Background: Achieving optimal color control in chairside CAD/CAM ultra-thin veneers, remains a significant challenge for dental clinicians and technicians. This study aims to investigate the effect of ultra-thin CAD/CAM medium translucency (MT) lithium disilicate veneers and tooth-colored resin substrates on final tooth shade and whiteness.

Materials And Methods: Disk-shaped ceramic veneers (IPS e.

Phosphotungstic acid-enhanced micro-computed tomography and RNA sequencing provide a new perspective on temporomandibular joint arthritis induced by complete Freund's adjuvant and collagen-induced arthritis in rat models.

Background/purpose: Temporomandibular joint (TMJ) arthritis causes inflammation and degradation of the mandibular condylar cartilage and subchondral bone. Complete Freund's adjuvant (CFA) and collagen-induced arthritis (CIA) are models for studying TMJ arthritis. While micro-computed tomography (micro-CT) is crucial for three-dimensional (3D) bone analysis, it has limitations in imaging nonmineralized tissues.

Differences in health care expenditure due to the comorbidity status of periodontal disease and diabetes mellitus.

Background: To investigate the differences in health care expenditure (HCE) due to the comorbidity status of periodontal disease (PD) and diabetes mellitus (DM).

Methods: This cohort study used health care claims and oral health screening data to identify participants with PD or DM and followed them for 1 year to assess their HCE. PD and DM were determined based on PD screening and medical claims data, respectively.

Differential expression of osteoblast-like cells on self-organized titanium dioxide nanotubes.

Background/purpose: Titanium dioxide nanotube (TNT) structures have been shown to enhance the early osseointegration of dental implants. Nevertheless, the optimal nanotube diameter for promoting osteogenesis remains unclear due to variations in cell types and manufacture of nanotubes. This study aimed to evaluate the differences in MC3T3-E1 and Saos-2 cells behavior on nanotubes of varying diameters.

Creating an extracellular matrix-like three-dimension structure to enhance the corrosion resistance and biological responses of titanium implants.

Background/purpose: Titanium (Ti) is extensively used in dental and orthopedic implants due to its excellent mechanical properties. However, its smooth and biologically inert surface does not support the ingrowth of new bone, and Ti ions may have adverse biological effects. The purpose is to improve the corrosion resistance of titanium and create a 3D structured coating to enhance osseointegration through a very simple and fast surface treatment.

Bidirectional longitudinal associations between subjective oral health and subjective well-being.

Objective: This study investigated the bidirectional longitudinal association between subjective oral health (SOH) and subjective well-being (SWB) over time.

Methods: This cohort study was based on a four-wave surveys conducted by the English Longitudinal Study of Aging. SOH was measured by oral impacts on daily performance (OIDP), self-rated oral health (SROH), and SWB was measured by the Center for Epidemiologic Studies-Depression (CES-D) scale, Control, Autonomy, Self-Realization, and Pleasure (CASP-19), and satisfaction with life scale (SWLS).

Artificial Intelligence in Dentistry: A Descriptive Review.

Artificial intelligence (AI) is an area of computer science that focuses on designing machines or systems that can perform operations that would typically need human intelligence. AI is a rapidly developing technology that has grabbed the interest of researchers from all across the globe in the healthcare industry. Advancements in machine learning and data analysis have revolutionized oral health diagnosis, treatment, and management, making it a transformative force in healthcare, particularly in dentistry.