Frequency of laughter and depression onset among older adults: A 6-year longitudinal study from the Japan Gerontological Evaluation Study.

Background: Laughter has been associated with mental and physical health benefits, but longitudinal evidence on whether laughter in daily life protects against depression remain limited. This study aimed to examine whether the frequency of laughter in daily life is associated with the risk of depression onset among older adults.

Methods: We analyzed data from 32,666 adults aged ≥65 years participating in the Japan Gerontological Evaluation Study, a three-wave cohort conducted over six-years.

Lifestyle-attributable burden of young-onset stroke in Chinese and global populations aged 20-54 years: A three decades comparative study (1990-2021) using Global Burden of Disease study data.

Introduction: Young-onset stroke represents a growing public health crisis globally along with rapid lifestyle changes. This study investigated the mortality and disability burden of young-onset stroke attributable to modifiable lifestyle factors in China compared with global trends, aiming to identify critical intervention targets.

Methods: Utilizing Global Burden of Disease 1990-2021 data, we analyzed age-stratified mortality and disability-adjusted life years for four lifestyle risk factors (tobacco, high alcohol use, dietary risk, and low physical activity).

Healthy lifestyle factors outweigh influence of APOE genetic risk on extending cognitively healthy life expectancy among Chinese older adults: evidence from a nationwide cohort study.

Introduction: Understanding the interplay between genetic factors and lifestyle choices in cognitive health is crucial for enhancing late-life quality. This study examines the effects of Apolipoprotein E (APOE) genotypes and healthy lifestyles on life expectancy with and without cognitive impairment (CI) in Chinese older adults.

Methods: Data from 6488 participants aged at least 65 in the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were analyzed using continuous-time three-state Markov models.

Quick accomplishment and responsiveness were associated with a lower risk of mortality from cardiovascular disease among Japanese older men: the Japan Collaborative Cohort Study.

Background: Quick accomplishment and responsiveness are behaviors related to time management by perceived control of time, such as a positive feeling of using one's time well. In recent years, positive psychological states have been associated with a lower risk of cardiovascular disease (CVD). Thus, we investigated the associations of quick accomplishment and responsiveness with CVD mortality in a large cohort study.

Association between oral health and multidimensional flourishing: A cross-sectional study from Japan Gerontological Evaluation Study (JAGES).

Purpose: Human flourishing is a multidimensional concept that encompasses happiness and life satisfaction (happiness), mental and physical health (health), meaning and purpose (purpose), character and virtue (character), and close social relationships (social), which are characterized by comprehensive well-being. This cross-sectional study investigated the association of oral health, number of remaining teeth, and prosthesis use with multidimensional flourishing.

Methods: Data was sourced from the 2022 wave of the Japan Gerontological Evaluation Study, a population-based survey of independent individuals aged 65 years or older.

Association of falls with risk of dementia and all-cause mortality: a cohort study of Japanese older adults with a 9-year follow-up.

Objective: Many risk factors affect dementia and all-cause mortality. However, whether falls are a risk factor for dementia and all-cause mortality is unclear. The study examines the association of falls with the risk of dementia and all-cause mortality, and whether dementia mediates the association of falls with all-cause mortality.

Taiso practice and risk of functional disability and dementia among older adults in Japan: The JAGES cohort study.

Background: Taiso is a Japanese term encompassing meanings akin to calisthenics. Taiso is a widely used exercise program in Japan but whether it prevents functional disability and dementia remains unclear. This study aimed to elucidate the association between practicing Taiso, especially focusing on the well-known Radio-Taiso, and functional disability and dementia in older adults in Japan.

Perceived Familial Financial Insecurity and Obesity Among Korean Adolescents During the COVID-19 Pandemic.

Background: In high-income countries, socioeconomically disadvantaged adolescents experience a higher risk of obesity, which may have been further exacerbated during the early phase of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to investigate the association between obesity and familial financial insecurity, utilizing data on subjective household socioeconomic status (SES) and perceived family-level financial deterioration induced by COVID-19.

Methods: We utilized data from the Korea Youth Risk Behavior Survey, a nationally representative sample of Korean adolescents, in 2020 and 2021.

Depression and the Risk of Dementia and All-Cause Mortality Among Japanese Older Adults: A 9-Year Longitudinal Study From JAGES.

Background: This study aims to investigate the association and dose-response relationship between depression, dementia, and all-cause mortality based on a national cohort study of older adults in Japan.

Methods: We conducted a longitudinal study of 44,546 participants ≥65 years from 2010-2019 Japanese Gerontological Evaluation Study. The Geriatric Depression Scale-15 was used to assess depressive symptoms and the long-term care insurance was used to assess dementia.

Socioeconomic Status Transition Throughout Life and Risk of Dementia.

Importance: Socioeconomic status (SES) is associated with dementia. However, the role of SES transitions in dementia is less explored; such evidence would be useful to understand whether social mobility is associated with healthy longevity at older ages.

Objective: To investigate the association of lifetime SES transition with risk of dementia.

Navigating Hurdles: A Review of the Obstacles Facing the Development of the Pandemic Treaty.

Introduction: The emergence of the COVID-19 pandemic has served as a call for enhanced global cooperation and a more robust pandemic preparedness and response framework. As a result of this pressing demand, dialogues were initiated to establish a pandemic treaty designed to foster a synchronized global strategy for addressing forthcoming health emergencies. In this review, we discussed the main obstacles to this treaty.

Daytime napping and the risk of gastric cancer: the JACC Study.

Background: Gastric cancer is a major cause of morbidity and mortality in Japan and worldwide. Emerging literature has suggested unfavorable health outcomes associated with daytime napping. Herein, we aimed to investigate the association between daytime napping and the risk of gastric cancer among Japanese people.

Retirement status after the age of 60 years modifies the association between anger expression and the risk of cardiovascular disease: The Circulatory Risk in Communities Study.

Aim: Anger expression is associated with an increased risk of cardiovascular disease. This positive association was confined to individuals with lower perceived social support and outdoor recreational activity. However, the effects of retirement status remain unclear.

Association between hypertension grades and cancer mortality among Japanese men and women.

Purpose: We aimed to examine the association between hypertension grades and the risk of total and site-specific cancer mortality among Japanese men and women.

Methods: In the Japan Collaborative Cohort Study, 27,332 participants aged 40-79 years were enrolled and followed up with their mortality until 2009. According to the measured blood pressure (BP) at baseline, we classified the participants into four BP categories based on 2018 European guidelines.

Reduced number of teeth with and without dental prostheses and low frequency of laughter in older adults: Mediation by poor oral function.

Purpose: Laughter is expected to have health-protective effects, but the potential link between tooth loss and laughter remains unclear. Therefore, this study aimed to examine the association between tooth loss and a low frequency of laughter among older adults in Japan, to elucidate whether this association could be mitigated by dental prostheses, and to evaluate the magnitude of the association mediated by poor oral function.

Methods: We used cross-sectional data from 157,708 functionally independent participants aged ≥65 years (46.

Sense of Coherence and Incident Dementia in Older Japanese Adults: The Japan Gerontological Evaluation Study.

Objectives: The sense of coherence refers to effectively using available resources to manage stress and promote overall health. Previous studies have linked it to various health outcomes; however, evidence regarding its association with the risk of incident dementia is limited. Hence, this study aimed to fill this research gap using data from a large-scale population survey.

Association between android fat mass, gynoid fat mass and cardiovascular and all-cause mortality in adults: NHANES 2003-2007.

Objectives: between android fat mass and gynoid fat mass with the mortality prediction is still limited. Current study analyzed the NHANES database to investigate the relationship between android fat mass, gynoid fat mass and CVD, with all-cause mortality.

Method: The study subjects were NHANES participants over 20 years old, two indicators of regional body composition, android fat and gynoid fat were measured by Dual Energy x-ray Absorptiometry (DEXA).