Clinicopathological features of dermal clear cell sarcoma: A series of 13 cases.

Background: Dermal clear cell sarcoma (DCCS) is a rare malignant mesenchymal neoplasm. Owing to the overlaps in its morphological and immunophenotypic profiles with a broad spectrum of tumors exhibiting melanocytic differentiation, it is frequently misdiagnosed as other tumor entities in clinical practice. By systematically analyzing the clinicopathological characteristics, immunophenotypic features, and molecular biological properties of DCCS, this study intends to further enhance pathologists' understanding of this disease and provide a valuable reference for its accurate diagnosis.

Bilateral Spontaneous Dissection of the Superficial Femoral Arteries (SFAs): A Case Report.

Spontaneous arterial dissection regarding the superficial femoral artery (SFA) is known to be an uncommon finding, and this clinical entity, when noted bilaterally, is exceptionally rare. Diagnosis is typically achieved by imaging modalities such as angio-tomography (angio-CT) or arteriography. This case report involves a 78-year-old male patient with a history of hypertension (HTN), cardiovascular disease, and arrhythmias who presented with leg pain and aches.

Retracted avulsion of the distal semimembranosus tendon: MRI evaluation and surgical repair.

Hamstring injuries constitute up to 30% of lower-extremity pathology and are the leading cause of time lost from competition in elite athletes. Although hamstring injuries frequently involve the proximal or mid-substance regions, distal injuries are particularly uncommon and are therefore sparsely studied. Among these, biceps femoris tears predominate, whereas those of the semimembranosus and semitendinosus are less common.

Evaluation of Paediatric Melanoma Management in a UK Major Tertiary Centre: A Twenty-Year Review.

Objectives: This study evaluates the management of paediatric melanoma at a tertiary centre, comparing clinical practices with international guidelines from the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) and the National Comprehensive Cancer Network (NCCN) to highlight real-world practices and make recommendations for future research priorities. The differences between conventional and Spitzoid melanomas were also explored in a subgroup analysis.

Background: Paediatric melanoma is rare and is most commonly caused by UV exposure or familial mutations.

99mTc/Tricine/HYNIC ubiquicidin 29-41 uptake in a giant cell tumor of the hallux: insights into the importance of time-activity curve analysis for accurate scan interpretation.

A 37-year-old man presented with swelling and erythema in the left first toe after a prior trauma, suspicious for osteomyelitis. X-ray and computed tomography (CT) scans revealed a radiolucent lesion with cortical disruption. A 99mTc/tricine/HYNIC ubiquicidin 29-41 (UBI) scintigraphy showed increased uptake but a non-accumulative time-activity curve, indicating a false positive for infection.

Fish Acellular Dermal Matrix Promotes Repair of Full-Thickness Skin Defects in Mice and Bama Pigs.

This study aimed to develop an acellular dermal matrix derived from tilapia skin and evaluate its potential as a bioscaffold for skin wound repair. Structural and compositional changes before and after decellularisation were assessed through histological staining, electron microscopy and immunological analysis. The matrix exhibited low immunogenicity, preserved extracellular matrix architecture and retained key bioactive components.

3D isotropic FastView MRI localizer allows reliable torsion measurements of the lower limb.

Computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to assess femoral and tibial torsion. While CT offers high spatial resolution, it involves ionizing radiation. MRI avoids radiation but requires multiple sequences and extended acquisition time.

Effectiveness of high-frequency repetitive transcranial magnetic stimulation coupled with rehabilitation in patients with spinal cord injury: a systematic review.

Background: Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.

[Dissociation of posttraumatic arteriovenous fistula on the leg].

Widespread fragmentation shells in combat operations with frequent multiple damage to organs and systems force to use all available diagnostic methods for treating severe injuries including lesion of great vessels of extremities. One of the consequences of these lesions is arteriovenous fistula (AVF). The last one may be asymptomatic at first.

Researcher's guide to preclinical animal models of acute extremity compartment syndrome.

Acute extremity compartment syndrome (CS) is a serious medical complication triggered by factors such as trauma, vascular injury, or prolonged compression, resulting in elevated intracompartmental pressure (ICP) and tissue ischemia. Diagnosis remains challenging, mainly relying on the subjective evaluation of clinical symptoms. Different animal models have been used to study pathophysiology and evaluate diagnostic and therapeutic approaches.

A multicenter epidemiologic analysis of the injuries affecting female and male collegiate basketball players.

Purpose: The global rise in popularity of basketball has prompted an increased emphasis on understanding the injury patterns affecting players. This study analysed injury epidemiology and return to sport outcomes in Division I male and female collegiate basketball players. The authors hypothesise that ankle injuries are amongst the most common in this population and that there are similarly comparable injury rates between genders.

Wound infection and pain one month after trauma: an underestimated threat.

Background: Pain is a common complication after combat injuries to the extremities. The role of nerve damage in the development of post-traumatic pain is recognized and described in the literature, superinfection as a potential factor has not been studied sufficiently.

Objective: To establish the relationship between the characteristics of the wound microbiota, the intake of different groups of antibiotics and the development of chronic pain in patients with traumatic injuries of the extremities.

Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses .

Introduction: Traditional models for studying wound healing, including 2D cell cultures and animal models, present substantial limitations in mimicking human skin physiology. In this study, we present a three-dimensional wounded skin equivalent (3DWoundSE) composed of human cells as a physiologically relevant platform to investigate wound healing processes.

Methods: The model builds upon a previously established 3D skin equivalent (3DSE) and incorporates a reproducible partial-thickness dermal punch wound.

Sequential treatment for diabetic foot ulcers in aortic dissection patients: a case report.

Diabetic foot ulcers (DFUs) represent a prevalent complication of diabetes, with a lifetime risk ranging from 15% to 25% among diabetic patients. Research indicates that anticoagulation plays a crucial role in the management of newly diagnosed cases of diabetic lower extremity atherosclerotic obliterative disease. However, in the present case, the patient developed dry gangrene in both toes after receiving vasodilator drugs during an emergency intervention for sudden aortic dissection.

Altered Sensorimotor Cortical Activities During Forearm Movement in Humans With Spinal Cord Injury.

Aims: Decoding the motor intention by electroencephalography to control external devices is an effective method of helping spinal cord injury (SCI) patients to regain motor function. Still, SCI patients have much lower accuracy in the decoding of motor intentions compared to healthy individuals, which severely hampers the clinical application. However, the underlying neural mechanisms are still unknown.

An occupational group with multiple musculoskeletal trauma and precarious employment: jockeys.

Jockeys endure considerable physical and psychological demands, rendering them vulnerable to occupational injuries such as fractures, concussions, and soft tissue damage. This descriptive case series presents the medical and occupational histories of three professional jockeys with long-term disabilities following work-related accidents. Each individual commenced their jockey career in early adolescence.

Lateral Lumbar Interbody Fusion (LLIF): Is Trans-Psoas Surgery Associated with Muscle Size Changes and Clinical Findings?

Introduction: Lateral Lumbar Interbody Fusion (LLIF) is based on a less-invasive access corridor through the retroperitoneum and psoas muscle, though concerns persist over postoperative weakness and neuropathy on the surgical side. This study investigates if the trans-psoas LLIF approach is associated with long-term changes in psoas morphology, hip flexor (HF) weakness, and lower extremity dysesthesia.

Methods: The authors retrospectively reviewed all LLIF cases at a single institution from January 2016 to June 2024.

Perioperative glucagon-like Peptide-1 receptor agonist use and clinical outcomes following lower extremity fracture fixation: A large retrospective cohort study with two year follow up.

Introduction: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly prescribed for Type 2 diabetes and obesity due to their cardiometabolic benefits. However, their effects on fracture healing remain controversial. This study investigates perioperative GLP-1 RA use and outcomes following surgical treatment of lower extremity (LE) fractures.

Characterizing Limb Loss and Absence in Military Health System Beneficiaries: Demographics, Causes, and Trends (2005-2023).

Introduction: An estimated 5.6 million individuals in the U.S.

Patients with vitamin D deficiency are more likely to develop complex region pain syndrome after extremity fractures: a large database propensity-matched cohort study.

Purpose: The purpose of this study was to investigate the association between preexisting vitamin D deficiency and the development of complex regional pain syndrome (CRPS) in patients with isolated extremity fractures.

Methods: The TriNetX database was queried to identify patients aged 18 and older who experienced upper or lower extremity fractures. Two cohorts were created based on the presence of vitamin D deficiency.

Compressive Neuropathy in the Upper Extremity: Pathophysiology, Diagnosis, and Treatment.

Background: Compressive neuropathy in the upper extremity is a common and often debilitating condition that significantly impacts function and quality of life. Despite its prevalence, the diagnosis, and management of compressive neuropathies remain complex with promising innovations. Plastic surgeons play a critical role in both surgical and nonsurgical interventions for these conditions.

An Antibiotic Spacer May Be Used to Acquire Adequate Tibia Length for a Transtibial Amputation to Prevent the Need for a Transfemoral Amputation: A Case Report.

Case: We present a case of a 30-year-old man who sustained a traumatic transtibial amputation from a motorcycle accident. Owing to significant posterior tibial bone loss, an antibiotic spacer was used to preserve below-knee amputation level and avoid conversion to a transfemoral amputation. At 2.

Relationship with sex-based anatomical differences to lower extremity injury severity in frontal crashes.

Objective: Multiple studies have demonstrated an increased risk of lower extremity injuries for females in frontal crashes. This study aimed to investigate whether sex-based anatomical differences, as measured on computed tomography (CT) scans of the abdomen and pelvis, contribute to lower extremity injury risk.

Methods: The Crash Injury Research and Engineering Network (CIREN) database (2017-2023) was queried for frontal collisions.

[S3 guidelines on intensive care medicine following polytrauma : Aspects regarding definitive surgical treatment].

The treatment of polytraumatized patients is challenging. Intensive efforts and interdisciplinary teamwork have improved survival rates of severely injured patients over the last decades. High quality guideline recommendations focusing on the prehospital setting, emergency room management and also the initial surgical phase have been published and are frequently updated.