Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Due to the inductive bias of convolutions, CNNs perform hierarchical feature extraction efficiently in the field of medical image segmentation. However, the local correlation assumption of inductive bias limits the ability of convolutions to focus on global information, which has led to the performance of Transformer-based methods surpassing that of CNNs in some segmentation tasks in recent years. Although combining with Transformers can solve this problem, it also introduces computational complexity and considerable parameters. In addition, narrowing the encoder-decoder semantic gap for high-quality mask generation is a key challenge, addressed in recent works through feature aggregation from different skip connections. However, this often results in semantic mismatches and additional noise. In this paper, we propose a novel segmentation method, X-UNet, whose backbones employ the CFGC (Collaborative Fusion with Global Context-aware) module. The CFGC module enables multi-scale feature extraction and effective global context modeling. Simultaneously, we employ the CSPF (Cross Split-channel Progressive Fusion) module to progressively align and fuse features from corresponding encoder and decoder stages through channel-wise operations, offering a novel approach to feature integration. Experimental results demonstrate that X-UNet, with fewer computations and parameters, exhibits superior performance on various medical image datasets.The code and models are available on https://github.com/XSJ0410/X-UNet.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neunet.2025.107943DOI Listing

Publication Analysis

Top Keywords

medical image
12
global context-aware
8
collaborative fusion
8
image segmentation
8
inductive bias
8
feature extraction
8
feature
5
x-uneta novel
4
global
4
novel global
4

Similar Publications

Artificial intelligence is revolutionizing health care, particularly in precision medicine and noninvasive diagnostics. Anemia, which is a widespread condition that affects billions of people worldwide, compromises oxygen transport due to low hemoglobin levels, which leads to severe complications if left undetected. Early and frequent monitoring is essential, yet traditional blood tests can be invasive, costly, and impractical for continuous assessment.

View Article and Find Full Text PDF

Rationale/objectives: Image-based vascular biomarkers may help expedite evaluation of chronic thromboembolic pulmonary hypertension (CTEPH), which remains difficult to diagnose despite available effective therapies. We sought to determine if vascular heterogeneity and central redistribution on chest CT differed between CTEPH, pulmonary arterial hypertension (PAH), and control groups.

Materials/methods: We retrospectively included 108 patients who underwent right heart catheterization and chest CT (2011-2018).

View Article and Find Full Text PDF

Background: Differentiating ischemic myelopathies from inflammatory demyelinating diseases is challenging due to overlapping imaging and clinical manifestations. Needle electromyography (EMG) is highly sensitive to spinal anterior horn damage.

Objectives: This study investigates the diagnostic value of spontaneous EMG activity in distinguishing ischemic myelopathies from inflammatory demyelinating diseases.

View Article and Find Full Text PDF

Remodeling the sarcoma microenvironment by simultaneous targeting of urokinase-type plasminogen activator receptors and epidermal growth factor receptors to promote antitumor activity.

J Pharmacol Exp Ther

August 2025

Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Center for Immunology

We evaluated the antitumor effects of remodeling the MC17 mouse sarcoma microenvironment (SME) by targeting urokinase-type plasminogen activator receptor (uPAR)- and epidermal growth factor receptor (EGFR)-expressing cells. Specifically, we used eBAT (a bispecific ligand-targeted toxin directed to EGFR and uPAR), and its mouse counterpart, meBAT, to ablate uPAR- and/or EGFR-expressing cells. We chose the MC17 model because the cells are resistant to eBAT, allowing us to exclusively evaluate the role of uPAR- and EGFR-expressing cells in the SME.

View Article and Find Full Text PDF

BACKGROUND Periprosthetic tibial fractures following total knee arthroplasty (TKA) are increasingly encountered in very elderly patients, where multiple comorbidities and osteoporosis compromise early mobilization and elevate the risk of complications. Maintaining pre-injury activities of daily living (ADL) while ensuring safe surgical management is challenging. We present a case of a 95-year-old woman with a periprosthetic tibial shaft fracture managed with open reduction, additional plate fixation, and Ilizarov external fixation, enabling immediate postoperative weight-bearing.

View Article and Find Full Text PDF