Background: Differentiating ischemic myelopathies from inflammatory demyelinating diseases is challenging due to overlapping imaging and clinical manifestations. Needle electromyography (EMG) is highly sensitive to spinal anterior horn damage.
Objectives: This study investigates the diagnostic value of spontaneous EMG activity in distinguishing ischemic myelopathies from inflammatory demyelinating diseases.
EClinicalMedicine
November 2023
Background: Glibenclamide alleviates brain edema and improves neurological outcomes in experimental models of stroke. We aimed to assess whether glibenclamide improves functional outcomes in patients with acute ischemic stroke treated with recombinant tissue plasminogen activator (rtPA).
Methods: In this randomized, double-blind, placebo-controlled trial, patients with acute ischemic stroke were recruited to eight academic hospitals in China.
Background Aims: Bone marrow-derived hematopoietic stem cell transplantation/hematopoietic progenitor cell transplantation (HSCT/HPCT) is widely used and one of the most useful treatments in clinical practice. However, the homing rate of hematopoietic stem cells/hematopoietic progenitor cells (HSCs/HPCs) by routine cell transfusion is quite low, influencing hematopoietic reconstitution after HSCT/HPCT.
Methods: The authors developed a micro-living motor (MLM) strategy to increase the number of magnetically empowered bone marrow cells (ME-BMCs) homing to the bone marrow of recipient mice.
We previously found that neurocritically ill patients are prone to refeeding syndrome (RFS), a potentially life-threatening complication. However, there is no unified or validated consensus on the screening tool for RFS so far. We aimed to validate and compare the performance of four screening tools for RFS in neurocritically ill patients.
View Article and Find Full Text PDFInterparental conflict has been found to positively affect adolescent delinquency; however, the underlying mechanism that explains this association remains unclear. This study investigated whether parental knowledge mediates the association between interparental conflict and adolescent delinquency, and whether this mediating process is moderated by deviant peer affiliation. To examine this, a total of 3,129 Chinese adolescents (47.
View Article and Find Full Text PDFAmong adolescents, exposure to community violence (ECV) has been consistently linked to problem behaviors such as Internet gaming disorder (IGD). However, the associated risk and protective factors have not been adequately explored in past studies. Therefore, in accordance with the risk-buffering model and social development model, this study aimed to test whether parental monitoring moderated the relationship between ECV and IGD among adolescents, and whether this moderating effect was mediated by affiliations with risk-taking peer groups.
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