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Purpose: Ventilation tube (VT) insertion is the most common surgical procedure in children, but there is known significant variation in post-operative management regimens. This Clinical Consensus Statement (CCS) aimed to establish an evidence-based framework for the follow-up management of children with VT.
Methods: Consensus was sought using a modified Delphi protocol among 23 international otolaryngologists (16 otologists and 7 pediatric otolaryngology specialists) of the IFOS (World ENT Federation). Forty statements were assessed by a 9-point Likert scale through a systematic literature review and three rounds of survey. The consensus level was rated as strong (mean ≥ 8.00, no outliers), consensus (mean ≥ 7.00, ≤ 1 outlier), near consensus (mean ≥ 6.50, ≤ 2 outliers), or no consensus.
Results: Nineteen out of 23 panelists scored the two Delphi rounds. From the 34 original statements, 4 reached strong consensus, 19 reached consensus, 4 reached near consensus, and 7 failed to reach consensus. The highest level of agreement was achieved regarding chronic otorrhea management, patient education protocols, and surveillance of retraction pockets. Different follow-up approach for short, intermediate and long tubes was proposed by the panel.
Conclusions: This CCS provides novel, evidence-based, comprehensive guidance for post-operative management of VT. The recommendations underscore individualized care with special emphasis on patient education and surveillance for complications.
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http://dx.doi.org/10.1007/s00405-025-09485-8 | DOI Listing |
J Crohns Colitis
September 2025
Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Background & Aims: Pregnancy can be a complex and risk-filled event for women with inflammatory bowel disease (IBD). High-quality studies in this population are lacking, with limited data on medications approved to treat IBD during pregnancy. For patients, limited knowledge surrounding pregnancy impacts pregnancy rates, medication adherence, and outcomes.
View Article and Find Full Text PDFJ Orthop Res
September 2025
Department of Mechanical Engineering, University of Louisville, Louisville, Kentucky, USA.
The use of cementless total knee arthroplasty (TKA) has significantly increased over the past decade. However, there is no objective criteria or consensus on parameters for patient selection for cementless TKA. The purpose of this study was to develop a machine learning model based on patient and radiographic parameters that could identify patients indicated for cementless TKA.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
September 2025
Pontifical Bolivarian University, Medellín, Colombia.
Introduction: Accurate diagnosis of subscapularis tears remains challenging due to the limitations of physical examinations and imaging techniques. Therefore, specific radiological parameters have been proposed as predictors of atraumatic subscapularis tears to improve diagnostic sensitivity and accuracy. These parameters include coracohumeral distance (CHD), coracoglenoid angle (CGA), coracoid angle (CA), coracoid overlap (CO), and coracohumeral angle (CHA).
View Article and Find Full Text PDFQual Life Res
September 2025
Department of Physical Therapy, Rady Faculty of Health Sciences, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada.
Purpose: The purpose was to identify how the ICECAP-A and ICECAP-O have been used with adults who have neurological health conditions.
Methods: Following the Joanna Briggs Institute framework, a scoping review was conducted, searching five databases (Scopus, CINAHL, MEDLINE, Embase, and PsycINFO). Studies were included if participants were adults (age 18+ years) with neurological health conditions, and ICECAP-A or ICECAP-O were used in the study.
Int Immunopharmacol
August 2025
Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Shanghai Engineering Research Center of Lung Transplantation, Shanghai, China. Electronic address:
Background: Protein lactylation has been implicated in stress-responsive cellular mechanisms, yet its role in lung transplantation-associated ischemia-reperfusion injury (IRI) remains undefined.
Methods: Transcriptomic profiles from GSE145989 were analyzed through differential expression analysis (limma) and weighted gene co-expression network analysis (WGCNA). Integrating the identified genes with lactylation-related signatures uncovered key lactylation-related genes (LRGs) as potential targets.