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Following the Starnes procedure, a progressive reduction in the RV cavity occurs, suggesting that the RV was unsuitable for a biventricular repair. For that reason, those patients traditionally followed the single ventricle pathway. In 2019, we performed the initial tricuspid valve (TV) repair cases after Starnes. Since then, we have routinely applied the staged treatment with Cone repair after Starnes achieving 2-ventricle or one-and-a-half ventricle repair in 17 patients. A Glenn procedure associated with pulmonary valve (PV) commissurotomy has been offered as an intermediate stage in patients with associated pulmonary atresia (PAt). Aiming to facilitate the following surgical steps and allow RV growth, we have described some maneuvers for these patients during the Starnes and the Glenn procedure. In this paper, we describe the up-to-date staged repair for critical neonatal Ebstein, emphasizing surgical details of the Starnes procedure, the intermediate interventions, and the Cone repair after Starnes.
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http://dx.doi.org/10.1053/j.pcsu.2025.02.007 | DOI Listing |
Retinal organoids (ROs) represent a promising regenerative strategy for restoring vision in retinal degenerative diseases, but whether host cone bipolar cells (BCs) in the primate macula can rewire with transplanted photoreceptors remains unresolved. Here, we transplanted genome-edited human retinal organoids lacking ON-BCs ( ROs) into a non-human primate macular degeneration model. Remarkably, host rod and cone BCs extended dendrites toward grafted photoreceptors, forming functional synapses confirmed by immunohistochemistry, ultrastructural imaging, and focal macular electroretinography.
View Article and Find Full Text PDFStomatologiia (Mosk)
September 2025
Samara State Medical University, Samara, Russia.
Objective: To determine the volume of augmentation necessary for adequate replacement of the alveolar bone defect in chronic generalized periodontitis, considering the dynamics of changes in the physical properties of its components in the postoperative period.
Material And Methods: The study analyzed the results of surgical treatment of 197 patients with chronic generalized periodontitis of moderate severity. In the main group (=97), treatment was performed using the author's method for determining the volume of an osteogenic graft; In the control group (=100), the required volume of augmentation was determined by previously known methods.
Hua Xi Kou Qiang Yi Xue Za Zhi
August 2025
Dept. of Stomatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116000, China.
Objectives: To evaluate the osteogenic efficacy of three-dimensional printing individualized titanium mesh (3D-PITM) as a scaffold material in guided bone regeneration (GBR).
Methods: 1) Patients undergoing GBR for alveolar bone defects were enrolled as study subjects, and postoperative healing complications were recorded. 2) Postoperative cone beam computed tomography (CBCT) scans acquired at least 6 months post-surgery were used to calculate the percentage of actual bone formation volume.
Hua Xi Kou Qiang Yi Xue Za Zhi
August 2025
Dept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Objectives: This study aims to evaluate the short- to medium-term clinical efficacy of demineralized dentin matrix (DDM) particles applied during the immediate implantation of alveolar bone defects in the posterior region.
Methods: A total of 76 patients with 110 simple taper retentive implants were included in the conducted study and divided into Groups A and B in accordance with the bone grafting materials. Cone beam computed tomography and panoramic radiographs were taken immediately after implant surgery, immediate crown repair, and final follow-up time.
Shanghai Kou Qiang Yi Xue
June 2025
Department of Pediatric Dentistry and Preventive Dentistry, School/Hospital of Stomatology, First Affiliated Hospital of Xinjiang Medical University. Urumqi 830054, China. E-mail:
Purpose: To study the stress effect and distribution pattern of the first and second primary molars on temporomandibular joint in the restoration of upper and lower teeth with stainless steel precrown using three-dimensional finite element method, in order to provide theoretical basis for clinical diagnosis and treatment.
Methods: CBCT data from one male and one female aged 3, 6, and 8 years old were collected, and the first and second maxillary molar teeth, upper and lower mandible, dentition and temporomandibular joint(TMJ) data were obtained respectively. Three-dimensional finite element method was used to create the finite element models of the first and second maxillary molar teeth, upper and lower mandible, dentition and TMJ, respectively.