Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1001/jamaophthalmol.2023.4731 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effect of oral belzutifan on retinal hemangioblastomas in von Hippel-Lindau syndrome.
Can J Ophthalmol
September 2025
University of British Columbia, Department of Ophthalmology and Visual Sciences, Vancouver, BC, Canada.
Objective: To assess the effect of belzutifan, a first-in-class oral hypoxia-inducible factor 2α inhibitor, on retinal hemangioblastoma (RH) outcomes.
Subjects/methods: This is a single-centre retrospective cohort study of patients with confirmed von Hippel-Lindau syndrome (VHLS) and RH. Subjects were taking oral belzutifan for renal cell carcinoma, central nervous system hemangioblastoma, or pancreatic neuroendocrine tumours.
A Multi-Task Deep Learning Pipeline Integrating Vessel Segmentation and Radiomics for Multiclass Retinal Disease Classification.
Photodiagnosis Photodyn Ther
September 2025
Department of Ophthalmology, People's Hospital of Feng Jie, Chongqing, 404600, China. Electronic address:
Objective: This study aims to develop a robust, multi-task deep learning framework that integrates vessel segmentation and radiomic analysis for the automated classification of four retinal conditions- diabetic retinopathy (DR), hypertensive retinopathy (HR), papilledema, and normal fundus-using fundus images.
Materials: AND.
Methods: A total of 2,165 patients from eight medical centers were enrolled.
Ab-Externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma:5-Year Safety Results from a Randomized, Multicenter Study.
Ophthalmol Glaucoma
September 2025
NIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, England; Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Purpose: To compare the long-term safety of MicroShunt implantation with trabeculectomy in eyes with primary open-angle glaucoma (POAG).
Methods: This was a 3-year observational extension of a 2-year prospective randomized trial comparing clinical outcomes of MicroShunt implantation with trabeculectomy, both augmented with mitomycin C. Adverse events (AEs), intraocular pressure (IOP), and IOP-lowering medication use were recorded 36, 48, and 60 months after initial randomization.
The Organization of Central Retinal Projections in Anna's Hummingbirds (Calypte anna) and Zebra Finches (Taeniopygia castanotis).
J Comp Neurol
September 2025
Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Hummingbirds (family Trochilidae) are easily recognized due to their unique ability to hover. Critical to hovering flight is head and body stabilization. In birds, stabilization during flight is mediated, among other things, by the detection of optic flow, the motion that occurs across the entire retina during self-motion.
View Article and Find Full Text PDFThe Liquid Crystal Monomer 3cH2B Affects the Visual System via Neural-Cell-Specific Retinoic Acid Disruption in the Optic Tectum.
Environ Sci Technol
September 2025
State Key Laboratory for Quality and Safety of Agro-Products, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Republic of China.
As a newly recognized type of emerging contaminant, liquid crystal monomers (LCMs) are widely distributed in the environment and human consumptions and their effects on visual systems and the underlying mechanisms are yet to be elucidated. Therefore, this study investigated the visual-neuro influence of 3cH2B (a frequently detected LCM) under environmentally relevant concentrations in zebrafish. The findings revealed that 40 μg/L 3cH2B induced visual behaviors after 40 days of exposure, which was accompanied by decreased retinoic acid (RA) levels and retinal structural deformation in the eyes.
View Article and Find Full Text PDF