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Purpose: To analyze the value of ultrasonography in predicting metachronous contralateral inguinal hernia (MCIH) and diagnosing contralateral persistent processus vaginalis (CPPV) in children with unilateral inguinal hernia, a prospective study was conducted.
Methods: All participants underwent a preoperative ultrasound on the contralateral groin. Patients in group A1 received operating procedure according to ultrasound results (patients with negative contralateral US results received hernia repair on the affected side), and patients in group A2 received operation according to laparoscopic results (patients received hernia repair and CPPV ligation). All patients were followed up 2 years and compared to a historical control (group B) who underwent open hernia repair only on the affected side regardless of contralateral US results.
Results: In groups A1 and A2, laparoscopic exploration revealed the presence of a CPPV in 490 cases. Ultrasound was found to be accurate in 104 out of the 490 cases with four false-positive and 386 false-negative results. This yielded an accuracy of 59.3%, a sensitivity of 21.2%, and a specificity of 99.2%. 10 patients in group A1, and 74 patients in group B developed MCIH. The accuracy, sensitivity, and specificity of the value of ultrasonography in predicting MCIH were 89.3%, 52.4%, and 92.5%, respectively.
Conclusions: Preoperative ultrasonography of the contralateral groin is currently unable to accurately detect CPPV, but it appears to be a promising method in predicting MCIH by using rigorous diagnosing criteria.
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http://dx.doi.org/10.1007/s00383-023-05612-w | DOI Listing |
Pathol Res Pract
September 2025
Department of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address:
Our research aims to ascertain the value of precursor and outgrowth lepidic in aiding the confirmation of multiple lung adenocarcinomas as separate primary lung cancers (SPLC). A total of 151 patients with metachronous multiple invasive adenocarcinomas were included in this study. Driver mutation tests(at least five genes: EGFR, ALK, KRAS, BRAF, and ROS1) were conducted on 302 tumors collected from 151 patients.
View Article and Find Full Text PDFJMIR Ment Health
September 2025
National Institute of Health and Care Research MindTech HealthTech Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Background: Cross-sector collaboration is increasingly recognized as essential for addressing complex health challenges, including those in mental health. Industry-academic partnerships play a vital role in advancing research and developing health solutions, yet differing priorities and perspectives can make collaboration complex.
Objective: This study aimed to identify key principles to support effective industry-academic partnerships, from the perspective of industry partners, and develop this into actionable guidance, which can be applied across sectors.
JMIR Public Health Surveill
September 2025
Department of Preventive Medicine, College of Medicine, Korea University, 73 Goryeodae-ro, Seoungbuk-gu, Seoul, 02841, Republic of Korea, 82 2-2286-1169.
Background: Scrub typhus (ST), also known as tsutsugamushi disease, is a common febrile vector-borne illness in South Korea, transmitted by trombiculid mites infected with Orientia tsutsugamushi, with rodents serving as the main hosts. Although vector-borne diseases like ST require both a One Health approach and a spatiotemporal perspective to fully understand their complex dynamics, previous studies have often lacked integrated analyses that simultaneously address disease dynamics, vectors, and environmental shifts.
Objective: We aimed to explore spatiotemporal trends, high-risk areas, and risk factors of ST by simultaneously incorporating host and environmental information.
Neuro Endocrinol Lett
September 2025
Faculty of Science, Jan Evangelista Purkyně University, Ústí nad Labem, Czech Republic.
Objective: In addition to hypogonadism, other endocrine disorders-particularly hyperprolactinemia-can significantly influence erectile dysfunction (ED) in men. The aim of our study was to evaluate the effect of normalizing prolactin (PRL) levels on erectile function in men diagnosed with ED and hyperprolactinemia. The primary outcome was improvement in IIEF-5.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2025
Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey.
Objective: It is important to raise awareness of the nutritional problems that can be overlooked during the follow-up visits with children who suffer from neuromuscular diseases, as these dietary differences may lead to additional neurological and systemic problems and impair the quality of life of the patient. The aim of this study was to evaluate the nutritional status of children with neuromuscular disorders and to prevent possible complications by recognizing possible nutritional problems in advance.
Methods: Patients who applied to the outpatient clinic at Cukurova University, Faculty of Medicine, Department of Pediatric Neurology beginning in April 2022 with a neuromuscular disorder diagnosis were followed up with and were included in the study.