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New and old subgrade stability is a crucial problem for widening projects in soft soil foundations because uncoordinated deformations can cause serious engineering accidents, even disasters. In order to ensure the stability of a widening expressway project near a pond in the Qinbei section, a series of on-site investigations, lab tests, and numerical analyses was performed. The settlement and displacement of on-site monitoring were carried out during the construction period to verify the analyzed results. It was found that the uneven settlement caused heavy settlement and displacement of the embankment; thus, net cracks and longitudinal cracks occurred in the expressway. The new embankment was also affected by the weak foundation; therefore, the foundation should be reinforced before the construction of the widening part. Considering the economy and effectiveness of the widening project, the replacement method was recommended for the weak foundation reinforcement based on the numerical analysis and on-site motoring results. Water pumping had a significant effect on the settlement of the embankment. Water pumping caused seepage in the foundation and increased the effective stress of the soil, making the foundation more consolidated. The pond slope should be reinforced before the construction of the embankment because it was not confined by the surrounding soil. Therefore, the slope soil could not provide sufficient passive soil pressure and easily slide.
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http://dx.doi.org/10.1038/s41598-022-24592-w | DOI Listing |
J Appl Toxicol
September 2025
Institute of Chinese Materia Medica, National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, China Academy of Chinese Medical Sciences, Beijing, China.
To compare the safety profiles of Gardeniae Fructus (Zhizi) and its counterfeit, Shuizhizi, Sprague-Dawley rats were orally administered aqueous extracts of Zhizi and Shuizhizi at 1.8 and 5.4 g/kg/day for 28 and 90 days, followed by a 28-day recovery period.
View Article and Find Full Text PDFNanomaterials (Basel)
August 2025
Mechanical and Electronic Engineering College, Shandong Agricultural University, Tai'an 271018, China.
The growing demand for low-frequency, broadband vibration and noise suppression technologies in next-generation mechanical equipment has become increasingly urgent. Effective negative mass locally resonant structures represent one of the most paradigmatic classes of acoustic metamaterials. Their unique elastic wave bandgaps enable efficient suppression of low-frequency vibrations, while inherent nonlinear effects provide significant potential for the design and tunability of these bandgaps.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Spinal Surgery, Xiangya Hospital, Central South University, Changsha, China.
The objective of this study is to assess global trends and cross-country inequalities in low back pain (LBP) and neck pain (NP) burdens among adolescents and adults aged 15 to 49 years from 1990 to 2021 and project the disease burden through 2036. Data from the 2021 Global Burden of Disease study were used to analyze trends in the prevalence and years lived with disability for LBP and NP from 1990 to 2021. Age-standardized prevalence rates (ASPR) and years lived with disabilities were calculated, and trends were assessed using the average annual percent change (AAPC).
View Article and Find Full Text PDFArch Public Health
August 2025
National Centre for Disease Prevention and Health Promotion, Italian National Institute of Health, Viale Regina Elena 299, Rome, 00161, Italy.
Background: Most governments worldwide introduced containment measures to protect people from the risk of SARS-CoV-2 virus infection which also affected children. The COVID-19 pandemic and the resulting confinement at home may have affected physical health and mental well-being especially among vulnerable young people, widening health disparities. Therefore, the aim of the EPaSS-ISS study was to study the changes in physical activity and sedentary behaviours among 8-9 years old Italian students during the pandemic of COVID-19 compared with before the pandemic.
View Article and Find Full Text PDFCancer Biol Med
August 2025
Department of Integrated Chinese and Western Medicine, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Objective: This study aimed to assess the global, regional, and national burden of early-onset gastric cancer (EOGC) and the attributable risk factors from 1990-2021 with projections extending to 2040.
Methods: The EOGC burden was quantified using incidence, prevalence, mortality, and disability-adjusted life years (DALYs) with calculation of age-standardized rates. The risk factor contributions were analyzed and disparities were evaluated using the slope index of inequality.