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Reservoir simulation is needed for forecasting hydrocarbon production, determining pressure and saturation, well planning, and field development, among other things. The primary objective is to estimate reservoir performance over a period of time and use that data to enhance hydrocarbon recovery under existing operating conditions. In commercial reservoir simulators, a large number of grid blocks are employed to capture the comprehensive information about a reservoir model, such as porosity and permeability, when the reservoir becomes heterogeneous and complicated. This large number of grid blocks is associated with a large number of mass balance equations that need to be solved simultaneously thereby increasing the amount of computational time it takes to solve them. During reservoir simulation, while moving from one-time level to the next requires a large number of iterations if the properties of reservoir fluids are pressure-sensitive. These further increases the computational cost needed during simulation. The primary objective of this paper is to present a novel approach for reservoir simulation that uses Random Forest (RF) which is one of the widely used Machine learning (ML) algorithm to reduce the number of iterations at each time step and speed up the process. This study investigated the benefits of employing the novel approach created using RF with an application to a conventional single-phase gas reservoir. The study's novelty is in developing a new ML-based reservoir simulator that will make reservoir simulation much faster and computationally more efficient. The standard physics-based system of equations has been included while the traditional reservoir simulation algorithm is modified.
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http://dx.doi.org/10.1016/j.heliyon.2022.e12067 | DOI Listing |
Biotechnol Appl Biochem
September 2025
Emergency Intensive Care Medicine Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China.
Background: Differentially expressed genes (DEGs) have been known to provide important information on disease mechanisms and potential therapeutic targets. The traditional Chinese medicine (TCM) offers a large reservoir of bioactive compounds that could modulate at these targets. This study is an attempt to investigate the biomarkers in Sepsis and COVID-19 using gene expression analysis and molecular modeling validation of TCM-derived candidate compounds targeting key DEGs associated with sepsis.
View Article and Find Full Text PDFLangmuir
September 2025
School of Resources and Safety Engineering, Chongqing University, Chongqing 400044, China.
Hydrogen energy is pivotal for driving sustainable development and achieving deep decarbonization; yet, its storage remains a significant challenge. Notably, depleted methane reservoirs can serve as a promising large-scale solution for underground hydrogen storage (UHS). Based on adsorption experiments, Monte Carlo and molecular dynamics methods, the adsorption behavior of H and CH in anthracite and the applicability of five models were discussed.
View Article and Find Full Text PDFMagn Reson Lett
May 2025
State Key Laboratory of Petroleum Resources and Engineering, China University of Petroleum (Beijing), Beijing, 102249, China.
Low-field nuclear magnetic resonance (NMR) has broad application prospects in the exploration and development of unconventional oil and gas reservoirs. However, NMR instruments tend to acquire echo signals with relatively low signal-to-noise ratio (SNR), resulting in poor accuracy of spectrum inversion. It is crucial to preprocess the low SNR data with denoising methods before inversion.
View Article and Find Full Text PDFChem Sci
August 2025
Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University Shanghai 200240 China
Adipic acid is an essential platform molecule for polymer production and is industrially manufactured by thermochemical oxidation of the cyclohexanone/cyclohexanol mixture (KA oil). Alternatively, electrifying provides a green and sustainable route to synthesizing adipic acid, but has been restricted by the low catalytic efficiency. Herein, we report that a nickel hydroxide electrocatalyst functionalized with 4,4'-bipyridine (Bipy-Ni(OH)) delivers a 3-fold greater productivity compared with that of pristine Ni(OH), achieving an excellent yield (90%) towards efficient adipic acid electrosynthesis.
View Article and Find Full Text PDFJ Environ Manage
September 2025
Ecological Modelling Laboratory, Department of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, Ontario, M1C 1A4, Canada. Electronic address:
Agriculture intensification represents an essential strategy to ensure food security for the growing human population, but it also poses considerable environmental concerns. Climate change and associated projections of an increased frequency of extreme precipitation and runoff events may amplify nutrient dynamics along the watershed-lake continuum, and could further exacerbate the poor water quality conditions downstream. Identifying hotspot locations with higher propensity for sediment and nutrient export and designing effective mitigation measures at the source is more critical than ever.
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