Quaternary stratigraphy of Bayan borehole in eastern Songnen Plain and its paleoclimate significance.

The Songnen Plain is a key region for Quaternary stratigraphic research in Northeast China. In this area, the Quaternary strata of the Bayan borehole reached a thickness of 58.00 m, offering excellent potential for investigation and research.

Deicing Mechanisms of Two-Phase Skeleton/Gel Composites with Tunable Surface Moduli.

Developing durable ice-phobic materials is essential for minimizing ice-related hazards in aerospace, transportation, and energy infrastructure systems. In this study, two types of porous skeleton-gel composites with distinct surface moduli were fabricated, i.e.

GTE-PPIS: a protein-protein interaction site predictor based on graph transformer and equivariant graph neural network.

Protein-protein interactions (PPIs) play a critical role in cellular functions, which are essential for maintaining the proper physiological state of organisms. Therefore, identifying PPI sites with high accuracy is crucial. Recently, graph neural networks (GNNs) have achieved significant progress in predicting PPI sites, but there is still potential for further enhancement.

An experimental study on the synergic damage of chemical solutions and stress to coal.

This paper investigates the impact of treatment with chemical solutions of varying pH values on the micro-macroscopic damage in coal samples under load, employing a combination of Small Angle X-ray Scattering (SAXS) experiments and uniaxial compression tests. The experimental results show that soaking coal samples in NaOH, HCl, and distilled water for 7 days leads to reductions in uniaxial compressive strength by 39.19%, 47.

Temporal trends in disability adjusted life year and mortality for colorectal cancer attributable to a high red meat diet in China from 1990 to 2021: an analysis of the global burden of disease study 2021.

Background: High red meat consumption is a main modifiable risk factor for colorectal cancer mortality (CRC), but its attributable disease burden remains unclear in China. We aimed to analyze the temporal trends in CRC deaths and disability-adjusted life years (DALYs) attributable to high red meat consumption in China from 1990 to 2021 and to predict the disease burden in the next 15 years.

Methods: Data was obtained from the Global Burden of Disease (GBD) 2021 study.

Controllable Structure Design of an Organic Gel-Infused Porous Surface for Efficient Anti- and De-icing.

Icing causes many problems in daily life and with equipment stability, and many efforts have been made to remove surface icing. Herein, a novel organic gel-infused porous material is developed to achieve excellent de-icing performance. Porous polydimethylsiloxane (P-PDMS) composites with different pore sizes were prepared by a template method.

DeepDualEnhancer: A Dual-Feature Input DNABert Based Deep Learning Method for Enhancer Recognition.

Enhancers are cis-regulatory DNA sequences that are widely distributed throughout the genome. They can precisely regulate the expression of target genes. Since the features of enhancer segments are difficult to detect, we propose DeepDualEnhancer, a DNABert-based method using a multi-scale convolutional neural network, BiLSTM, for enhancer identification.

Vocalization-induced middle ear muscle reflex and auditory fovea do not contribute to the unimpaired auditory sensitivity after intense noise exposure in the CF-FM bat, Hipposideros pratti.

Behaviors and auditory physiological responses of some species of echolocating bats remain unaffected after exposure to intense noise, but information on the underlying mechanisms remains limited. Here, we studied whether the vocalization-induced middle ear muscle (MEM) contractions (MEM reflex) and auditory fovea contributed to the unimpaired auditory sensitivity of constant frequency-frequency modulation (CF-FM) bats after exposure to broad-band intense noise. The vocalizations of the CF-FM bat, Hipposideros pratti, were inhibited through anesthesia to eliminate the vocalization-induced MEM reflex.

Cervical extracellular matrix hydrogel optimizes tumor heterogeneity of cervical squamous cell carcinoma organoids.

Cervical cancer, primarily squamous cell carcinoma, is the most prevalent gynecologic malignancy. Organoids can mimic tumor development in vitro, but current Matrigel inaccurately replicates the tissue-specific microenvironment. This limitation compromises the accurate representation of tumor heterogeneity.

High albumin-bilirubin grade predicts worse short-term complications in gastric cancer patients with metabolic syndrome: a retrospective study.

Background: Preoperative albumin-bilirubin (ALBI) grade has been proposed and applied in recent years to evaluate the prognosis of liver cancer, but its role in gastric cancer (GC) is still unclear. This research aimed to examine the prognostic value of ALBI grade after gastrectomy among patients with GC complicated with metabolic syndrome (MetS).

Methods: There were 628 patients who received radical resection for GC.

Detection of Rickettsia spp. and Anaplasma ovis in Melophagus ovinus from southern Xinjiang, China.

Melophagus ovinus is a hematophagous insect that is distributed worldwide and plays a crucial role in transmitting disease-causing pathogens. From June 2021 to March 2022, a total of 370 M. ovinus were collected from 11 sampling points in southern Xinjiang, China.

Detection of Spp., Spp., and in from Southern Xinjiang, China.

Introduction: Ticks are blood-sucking arthropods that have negative economic impacts and can spread a variety of diseases through their bites. There are few reports on soft ticks (Acari: Argasidae) and tick-borne pathogens in southern Xinjiang, China. This investigation supplements the available information for this region and is concerned with an argasid tick, apicomplexan parasites of the and genera and a bacterium of the genus.

Distribution and Molecular Epidemiology of in and Small Ruminants in Border Regions of South Xinjiang, China.

are obligate intracellular bacteria that can endanger human and animal health, and they can be transmitted by arthropod vectors, such as and ticks. In this study, 433 specimens, including 370 and 63 sheep blood samples, were collected from nine districts of South Xinjiang to investigate the distribution and molecular epidemiology of in and small ruminant. DNA of was detected in 109 (25.

The Association Between Visceral Obesity and Postoperative Outcomes in Elderly Patients With Colorectal Cancer.

Background: The impact of visceral obesity on the postoperative complications of colorectal cancer in elderly patients has not been well studied. This study aims to explore the influence of visceral obesity on surgical outcomes in elderly patients who have accepted a radical surgery for colorectal cancer.

Methods: Patients aged over 65 year who had undergone colorectal cancer resections from January 2015 to September 2020 were enrolled.

ZIC2 promotes colorectal cancer growth and metastasis through the TGF-β signaling pathway.

ZIC2 is involved in the tumor progression of many types of cancers. The role of ZIC2 in the metastasis of colorectal cancer and its mechanism are not yet clear. In this study, we found that high ZIC2 expression was not only associated with poor prognosis, relapse-free survival and advanced metastasis but was also an independent prognostic factor in colorectal cancer patients.

Global leadership initiative in malnutrition (GLIM) criteria using hand-grip strength adequately predicts postoperative complications and long-term survival in patients underwent radical gastrectomy for gastric cancer.

Background: The present study aims to investigate whether malnutrition defined by the Global Leadership Initiative in Malnutrition (GLIM) criteria using hand-grip strength (HGS) adequately predict postoperative complications and long-term survival in patients underwent radical gastrectomy for gastric cancer in a similar manner to GLIM-defined malnutrition using skeletal muscle index (SMI).

Methods: Patients who underwent radical gastrectomy for gastric cancer from August 2014 to June 2019 were included in this study. Clinical data were prospectively collected.

Impact of Body Composition and Physical Function on Quality of Life After Gastrectomy for Gastric Cancer.

Purpose: Patients with gastric cancer after gastrectomy often suffer from a decline in their quality of life (QoL), but the relationship between body composition (BC) and physical function on QoL has rarely been studied. This study aims to evaluate and determine the changes in QoL after gastrectomy and the impact of BC and physical function on QoL.

Methods: A total of 311 gastric cancer patients completed EORTC QLQ-C30 and EORTC QLQ-STO22 questionnaires before and 1, 3, 6 months post-surgery.

Effect of GLIM-defined malnutrition on postoperative clinical outcomes in patients with colorectal cancer.

Background: Malnutrition is common in colorectal cancer patients. Malnutrition is recognized as a risk factor for adverse postoperative outcomes, yet there are no consistent diagnostic criteria for it. Thus, the Global Leadership Initiative on Malnutrition published new universal criteria.

Double MOF gradually activated S bond induced S defect rich MILN-based Co(z)-NiMoS for efficient electrocatalytic overall water splitting.

Herein, cactus like nanorods with rich S defects and functional group MILN-based Co(z)-NiMoS are synthesized through a facile method. First, we prepared MIL-88B precursor to give a fairly dispersed frame structure, and then Co was doped into disulfides, which are rich in sulfur bonds, and the imidazole group was cleverly connected into graphitized carbon self-etching of ZIF-67. The doping of Co and functional groups makes tiny changes in the sulfide lattice, which promotes the unsaturation degree of the S bond and activates it gradually.

The relationship between the GLIM-defined malnutrition, body composition and functional parameters, and clinical outcomes in elderly patients undergoing radical gastrectomy for gastric cancer.

Objective: The present study aims to determine the correlations between Global Leadership Initiative in Malnutrition (GLIM)-defined malnutrition and body composition and functional parameters, and to comprehensively analyze the predictive value of GLIM-defined malnutrition for postoperative outcomes in the context of detailed measurement of body composition and functional parameters in elderly patients who underwent radical gastrectomy for gastric cancer.

Methods: Elderly patients (aged ≥65 years) who underwent radical gastrectomy for gastric cancer from August 2014 to June 2019 were included. Malnutrition was diagnosed using the GLIM criteria.

Measurement of muscle quantity/quality has additional predictive value for postoperative complications and long-term survival after gastrectomy for gastric cancer in patients with probable sarcopenia as defined by the new EWGSOP2 consensus: Analysis from a large-scale prospective study.

Objectives: We investigated whether measurement of muscle quantity/quality has additional predictive value for postoperative complications and long-term survival after gastrectomy for gastric cancer in patients with probable sarcopenia, as defined by the new European Working Group on Sarcopenia in Older People 2 consensus.

Methods: We conducted a prospective study of patients who underwent a radical gastrectomy for gastric cancer between August 2014 and June 2019. Muscle strength was measured using a handgrip dynamometer.

Value of muscle quality, strength and gait speed in supporting the predictive power of GLIM-defined malnutrition for postoperative outcomes in overweight patients with gastric cancer.

Background: The present study aims to investigate the prognostic value of Global Leadership Initiative in Malnutrition (GLIM)-defined malnutrition in overweight patients who underwent gastrectomy for gastric cancer, and to explore whether the addition of muscle quality, strength and gait speed could improve the predictive power for postoperative outcomes.

Methods: Overweight patients (body mass index (BMI) ≥23 kg/m) who underwent radical gastrectomy for gastric cancer were included in this study. Malnutrition was diagnosed using the two-step approach following the GLIM criteria.

Influence of body composition, muscle strength, and physical performance on the postoperative complications and survival after radical gastrectomy for gastric cancer: A comprehensive analysis from a large-scale prospective study.

Background: Few studies have comprehensively analyzed the correlations among body composition parameters, muscle strength, and physical performance, as well as the influence of these factors on the postoperative complications and survival after radical gastrectomy for gastric cancer.

Methods: A prospective study was conducted including patients who underwent radical gastrectomy for gastric cancer from August 2014 to June 2019. Skeletal muscle index (SMI), skeletal muscle density (SMD), visceral fat area (VFA), subcutaneous fat area (SFA) was obtained by measurement of preoperative computed tomography (CT) images.

Highly Stretchable and Wearable Strain Sensor Based on Printable Carbon Nanotube Layers/Polydimethylsiloxane Composites with Adjustable Sensitivity.

Strain sensors that are capable of monitoring complex human motions with high accuracy are highly desirable for developing wearable electronics. This paper reports the fabrication of highly stretchable and sensitive multidirectional strain sensors with tunable strain gauge factors by employing a digitally controlled printer to incorporate carbon nanotube (CNT) layers into polydimethylsiloxane (PDMS) substrates. The fabricated sensors exhibit a high stretchability (up to 45%) and sensitivity with a gauge factor of 35.