Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

As there are few studies of spp. infection in cats in China, or anywhere in the world, the aim of this study was to explore the epidemic features of babesiosis in pet cats in China. In total, 429 blood samples were randomly collected in four different geographical regions. The 18S rRNA gene fragment of spp. was amplified by nest polymerase chain reaction (PCR), and haplotype and phylogenetic analysis of were performed to analyze the relationship of this protozoa. The total positive rate of infection was 2.8%. BLAST analysis indicated that was detected in 12 cats. Among these, 4.3%, 3.1%, 0.8% and 2.0% were from Chongqing, Fujian, Hubei and Shandong, respectively. Haplotype and phylogenetic analysis showed that there were nine haplotypes and no obvious genetic variation among populations. These findings will be helpful for understanding the epidemiology of spp. in China, and provide a foundation for developing effective preventative strategies.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686484PMC
http://dx.doi.org/10.3390/ani12223066DOI Listing

Publication Analysis

Top Keywords

cats china
12
haplotype phylogenetic
8
phylogenetic analysis
8
molecular detection
4
cats
4
detection cats
4
china
4
china studies
4
studies spp
4
spp infection
4

Similar Publications

A bivalent SARS-CoV-2 subunit vaccine for cats neutralizes both the original ancestral strain and BA.1 Pseudovirus carrying the 453F and 501 T mutation.

Vaccine

September 2025

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China; Hubei Jiangxia Laboratory, Wuhan 430200, China. Electronic address:

The spillover and spillback of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) between humans and animals, especially companion animals, threaten global public health security. However, risk assessment of SARS-CoV-2 variants infecting companion animals and the development of corresponding prevention and control technologies are lacking. The aim of this study is to assess the potential risk of enhancement of the infectivity of SARS-CoV-2 in cats owing to mutations at key sites within the spike (S) protein receptor-binding domain (RBD) region and develop an efficient vaccine to cross-neutralize high-risk SARS-CoV-2 variants.

View Article and Find Full Text PDF

Feline infectious peritonitis virus (FIPV) can cause an immune-mediated disease that is fatal to felines, but there is a lack of clinically effective protection conferred by vaccines. The methyltransferase (MTase) activity of the coronavirus nonstructural proteins nsp14 and nsp16 affects virulence, but there are no studies on the effect of nsp14 and nsp16 mutations affecting enzyme activity on the virulence of FIPV. In this study, we successfully rescued two mutant strains based on the previous infectious clone QS-79, named FIPV QS-79 dnsp14 and dnsp16, by mutating the MTase active sites of nsp14 (N415) and nsp16 (D129).

View Article and Find Full Text PDF

Introduction: Feline herpesvirus type 1 (FHV-1) is a primary pathogen causing feline upper respiratory tract diseases (FURTD), but its impact on the upper respiratory tract microbiota remains unclear. This study aimed to evaluate the impact of FHV-1 infection on the upper respiratory tract microbiota by comparing the microbial composition between FHV-1-positive group with FHV-1-negative group.

Methods: The microbial diversity in the upper respiratory tract of FHV-1-positive cats ( = 8) were analyzed using 16S rRNA high-throughput sequencing, and then this diversity was compared with that in healthy FHV-1-negative controls ( = 4).

View Article and Find Full Text PDF

Sedative and echocardiographic effects of intranasal or intramuscular administration of dexmedetomidine in healthy cats.

J Feline Med Surg

September 2025

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.

ObjectivesThe aim of the present study was to evaluate the sedative and echocardiographic effects of dexmedetomidine (DEX) administered via intranasal (IN) and intramuscular (IM) routes in cats.MethodsThis randomised, blinded crossover study involved eight healthy adult cats. Cats were randomly allocated to receive DEX 10 μg/kg via either the IN or IM routes.

View Article and Find Full Text PDF

() is a major causative agent of feline viral rhinotracheitis and ocular lesions. Due to its large DNA genome, the construction of recombinant viruses presents considerable challenges for conventional methodologies. In this study, we implemented an integrated strategy combining CRISPR/Cas9-mediated gene editing with fluorescence-activated cell sorting (FACS) to enable the rapid and efficient generation of recombinant viruses.

View Article and Find Full Text PDF