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Article Abstract

Growth traits are important economic characteristics of livestock and poultry. In the present study, the expression features of and the relationship between gene polymorphisms and growth traits in Hu sheep were investigated by using real-time quantitative PCR technology (qPCR), Sanger sequencing, and Kaspar genotyping technology. The qPCR results showed that the gene is expressed widely in the tested tissues of Hu sheep, and the expression level of the gene in the heart and the muscle was significantly higher than in other tissues ( < 0.05). Missense mutation c.62565119 A > G was found in , and an association analysis showed that it was correlated with the growth traits (body weight, body height, and body length) of Hu sheep ( < 0.05). The body weight, body height, and body length of the sheep carrying the AA genotype were remarkably higher than those of the GG and AG genotypes ( < 0.05). These results showed that novel polymorphisms at the gene can be used as a genetic marker of growth traits of Hu sheep.

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http://dx.doi.org/10.1080/10495398.2022.2138413DOI Listing

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