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Bifidobacteria are among the predominant microorganisms during infancy, being a dominant microbial group in the healthy breastfed infant and playing a crucial role in newborns and infant development. Not only the levels of the genus but also the profile and quantity of the different bifidobacterial species have been demonstrated to be of relevance to infant health. Although no definitive proof is available on the causal association, reduced levels of bifidobacteria are perhaps the most frequently observed alteration of the intestinal microbiota in infant diseases. Moreover, strains have been extensively studied by their probiotic attributes. This review compiles the available information about bifidobacterial composition and function since the beginning of life, describing different perinatal factors affecting them, and their implications on different health alterations in infancy. In addition, this review gathers exhaustive information about pre-clinical and clinical studies with strains as probiotics in neonates.
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http://dx.doi.org/10.3390/microorganisms9122415 | DOI Listing |
Commercially processed complementary foods (CPCFs) are consumed in Kenya, but little is known about caregiver perceptions and reasons for their consumption. We explored caregiver perceptions, motivations and reasons for purchasing CPCFs. This cross-sectional mixed-methods study was conducted in Nairobi among caregivers of children aged 6-23 months.
View Article and Find Full Text PDFJ Crohns Colitis
September 2025
Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Background & Aims: Pregnancy can be a complex and risk-filled event for women with inflammatory bowel disease (IBD). High-quality studies in this population are lacking, with limited data on medications approved to treat IBD during pregnancy. For patients, limited knowledge surrounding pregnancy impacts pregnancy rates, medication adherence, and outcomes.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Psychology, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute (ACHRI), Calgary, AB, Canada; Department of Educational and Counselling Psychology, and Special Education (ECPS), University of British Columbia, BC, Canada.
Background: Perinatal depression has been linked to higher negative affectivity (NA) in children, though the strength of this association is variable. Infant sleep, a known protective factor, may moderate this relationship though this has not been tested.
Objective: To examine whether within-person changes in depressive symptoms across pregnancy and postpartum were linked to child NA, and whether infant sleep duration moderated these effects.
Ann Epidemiol
September 2025
School of Public Health, Peking University, Beijing, China. Electronic address:
Purpose: We estimated the association between maternal sexually transmitted diseases (STDs) and the risk of specific birth defects among live singleton births in the United States (US).
Methods: We conducted a population-based study using data from birth certificates for 14,602,822 live singleton births occurring from 2016 to 2019 in the US. We used logistic regression to estimate the associations between three maternal STDs (chlamydia, gonorrhea, and syphilis) and the risk of four specific birth defects (gastroschisis, cleft lip with or without cleft palate, spina bifida, and hypospadias), adjusting for socio-demographic and pregnancy-related factors.
Infant Behav Dev
September 2025
School of Psychotherapy, Psychology and Counselling, Regent's University London, Inner Circle, Regent's Park, London NW1 4NS, United Kingdom. Electronic address:
COVID-19 restrictions had a significant impact on family life, including daily activities and routines. This study aimed to explore the impact of the COVID-19 pandemic on children's sleep and feeding behaviours, through undertaking reflexive thematic analysis of parents' open-text box responses to survey questions related to their child's sleep and feeding practices during COVID-19 restrictions. Six hundred and ninety one parents of children aged 0-24 months old who were living in the United Kingdom completed an online questionnaire between 14th December 2020 and 15th January 2021.
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