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Optical coherence tomography (OCT) technology can obtain a clear retinal structure map, which is greatly beneficial for the diagnosis of retinopathy. Ophthalmologists can use OCT technology to analyze information about the retina's internal structure and changes in retinal thickness. Therefore, segmentation of retinal layers in images and screening for retinal diseases have become important goals in OCT scanning. In this paper, we propose the multiscale dual attention (MSDA)-UNet network, an MSDA mechanism network for OCT lesion area segmentation. The MSDA-UNet network introduces position and multiscale channel attention modules to calculate a global reference for each pixel prediction. The network can extract the lesion area information of OCT images of different scales and perform end-to-end segmentation of the OCT retinopathy area. The network framework was trained and tested on the same OCT dataset and compared with other OCT fluid segmentation methods to assess its effectiveness.
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http://dx.doi.org/10.1364/AO.426053 | DOI Listing |
Nucleic Acids Res
September 2025
School of Software, Shandong University, Jinan 250101, Shandong, China.
Spatial transcriptomics (ST) reveals gene expression distributions within tissues. Yet, predicting spatial gene expression from histological images still faces the challenges of limited ST data that lack prior knowledge, and insufficient capturing of inter-slice heterogeneity and intra-slice complexity. To tackle these challenges, we introduce FmH2ST, a foundation model-based method for spatial gene expression prediction.
View Article and Find Full Text PDFFood Res Int
November 2025
College of Food Science and Engineering, Henan University of Technology, Zhengzhou, China. Electronic address:
The formation and recrystallization of ice crystals during freezing causes irreversible structural damage to the dough matrix, which is characterized by the cold denaturation of the gluten protein structure and the degradation of the gluten network structure. Polysaccharides are widely used to improve the quality of frozen dough owing to their excellent water-holding and viscosity. Current research has shown that polysaccharides mitigate the physical damage of ice crystals on the gluten protein structure mainly by modifying the water status of frozen dough to inhibit the ice crystallization process.
View Article and Find Full Text PDFBiomed Phys Eng Express
September 2025
College of Computer Science and Technology, China University of Petroleum East China - Qingdao Campus, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China, Qingdao, Shandong, 266580, CHINA.
Purpose: Cerebrovascular segmentation is crucial for the diagnosis and treatment of cerebrovascular diseases. However, accurately extracting cerebral vessels from Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) remains challenging due to the topological complexity and anatomical variability.
Methods: This paper presents a novel Y-shaped segmentation network with fast Fourier convolution and Mamba, termed F-Mamba-YNet.
Adv Healthc Mater
September 2025
Department of Physics, Department of Materials Science and Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.
Although cold atmospheric plasma is a promising therapeutic technique for tumor immunotherapy via reactive oxygen and nitrogen species (RONS), the challenges associated with the generation and delivery of these RONS hamper clinical adoption. Herein, a dual-mode hybrid discharge plasma-activated sodium alginate hydrosols (PAH) is proposed to enhance the antitumor immune response. Gaseous highly reactive RONS are generated by dual-mode hybrid plasma produced by mixed O and NO modes, which are converted into aqueous RONS in PAH via gas-liquid reactions between plasma and hydrosols.
View Article and Find Full Text PDFNeural Netw
August 2025
Hunan Provincial Key Laboratory of Intelligent Computing and Language Information Processing, Hunan Normal University, Changsha, 410081, China. Electronic address:
The key challenges in kidney tumor segmentation include unpredictable location, high similarity among objects, and variability in boundaries. Existing approaches mostly handle these challenges from an object-agnostic perspective or a single decoupling perspective, which limits their ability to address all the aforementioned challenges. To tackle these problems, we propose a Dual-perspective Decoupling Network (DDNet), which consists of the Dual-perspective Decoupling Module (DDM) and the Edge Refinement Module (ERM).
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