Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0002-9149(03)00029-8DOI Listing

Publication Analysis

Top Keywords

effects high
4
high doses
4
doses versus
4
versus standard
4
standard doses
4
doses enalapril
4
enalapril endothelial
4
endothelial cell
4
cell function
4
function patients
4

Similar Publications

Maladaptive role of peridroplet mitochondria during lipophagy disruption in pancreatic cancer.

Biochem Biophys Res Commun

September 2025

Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba, 260-8675, Japan. Electronic address:

Pancreatic ductal adenocarcinoma (PDAC) cells exhibit high metabolic flexibility, enabling survival under glucose limitation by using alternative fuels such as fatty acids. Lipophagy, a selective form of autophagy targeting lipid droplets (LDs), supports mitochondrial respiration during such nutrient stress. Our previous study demonstrated that the LSD1 inhibitor SP-2509 disrupts lipophagy independently of LSD1 inhibition, leading to LD accumulation and ATP depletion in glycolysis-suppressed PDAC cells.

View Article and Find Full Text PDF

Light-emitting diode-derived blue light overexposure accelerates corneal endothelial cell aging by inducing abnormal ROS accumulation.

J Photochem Photobiol B

September 2025

The First Affiliated Hospital, Department of Ophthalmology, Hengyang Medical school, University of South China, Hengyang, Hunan 421001, China; Xiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center

Blue light, defined as short-wavelength visible light ranging from 400 to 500 nm, is recognized for its high energy within the visible light spectrum. The prevalent use of light-emitting diodes (LEDs) has significantly increased exposure to blue light. Corneal endothelial cells (CECs) playing a crucial role in maintaining corneal transparency to get clear visual field.

View Article and Find Full Text PDF

Legumes form symbioses with nitrogen-fixing bacteria, well studied metabolically but less so in terms of respiration. Symbiotic nitrogen fixation demands high respiratory ATP and carbon skeletons, linking nitrogen assimilation and both NADH- and ATP-dependent process to mitochondrial respiration. The plant mitochondrial electron transport chain contains two terminal oxidases that differentially fractionate against O, providing estimations in vivo of the energy efficiency of respiration.

View Article and Find Full Text PDF

Synthetic cathinones (SCs) are drugs of abuse that act on the central nervous system, producing psychoactive effects similar to those of amphetamines. Their greater accessibility compared with the traditional amphetamine-type stimulants has contributed to their increasing popularity in recent years. The analysis of SCs in biological samples is essential for documenting their consumption.

View Article and Find Full Text PDF

With the rapid development of genomic sequencing technologies, there is an increasing demand for efficient and accurate sequence analysis methods. However, existing methods face challenges in handling long, variable-length sequences and large-scale datasets. To address these issues, we propose a novel encoding method-Energy Entropy Vector (EEV).

View Article and Find Full Text PDF