Confinement-Induced In Situ Cl/Cl Conversion in a Cathode Enables a Lean Electrolyte Sodium-Chlorine Battery.

Rechargeable metal-chlorine (Li/Na-Cl) batteries potentially have a high energy density, but the significant amount of electrolyte consumed to produce active metal chlorides for reversible chlorine conversion severely limits their real electrochemical performance. Herein, we use a cathode with precast metal chloride in the graphene layers as the initial active material to save the sacrificial electrolyte and deliver a fundamentally different start-up operation mode for metal-chlorine batteries. Furthermore, the metal chloride confined by the graphene layers achieves in situ confining conversion with gaseous chlorine during long cycling, causing substantially improved cathode kinetics in a lean electrolyte.

Molecular Engineering of Intrinsic Chromophoric Polyimides: Chemically Amplified Color Photoresists for Advanced Optical Systems.

Color photoresists represent a cornerstone technology in advanced optical systems, enabling critical functionalities ranging from flexible display pixel manufacturing to direct lithography of antidust color coatings for space exploration equipment. While conventional dye-polymer composite photoresists dominate industrial applications, their intrinsic limitations in thermal stability, mechanical durability, electrical insulation, and long-term color stability fundamentally restrict their deployment in extreme environments. This study pioneers a molecular engineering strategy to overcome these challenges through the development of intrinsically colored photosensitive polyimides (PSPIs).

The Structural Deciphering of the α3 Helix Within ZmHsfA2'S DNA-Binding Domain for the Recognition of Heat Shock Elements in Maize.

Heat shock transcription factor (Hsf) plays a pivotal role in regulating plant growth, development, and stress responses. Hsf activates or represses target gene transcription by binding to the heat shock element (HSE) of downstream genes. However, the specific interaction sites between Hsf and the HSE in the promoter remain unclear.

Hot Interband Carrier Exploitation in a Ru/MOF Schottky Junction for Photocatalytic CO Reduction.

Visible light-driven photocatalytic reduction of CO to value-added fuels and chemicals has attracted extensive interest for decades. However, the emerging photocatalysis paradigm through an interband transition in non-plasmonic metals remains challenging. Herein, a new strategy, namely hot carrier exploitation is demonstrated, for highly efficient CO reduction through the interband transition in non-plasmonic Ru nanoparticles (NPs).

Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report.

The present study reports on the case of a middle-aged female patient who presented with a rapidly progressing pigmented skin lesion on the periphery, combined with multiple intracranial, pulmonary, hepatic and skeletal malignancies. The case was not clear in terms of histopathological manifestations and other aspects, which made the diagnosis of melanoma difficult. The present case details the challenges in the diagnostic process, as well as the importance of multidisciplinary comprehensive diagnosis and treatment, aiming to provide a reference for clinicians when dealing with similar complex pigmented skin lesions.

Role of ferroptosis in breast cancer: Molecular mechanisms and therapeutic interventions.

Ferroptosis, an iron-dependent cell death pathway distinct from apoptosis, is crucial in breast cancer (BC) research, especially for overcoming resistance in triple-negative breast cancer (TNBC). Unlike traditional apoptosis, ferroptosis involves the glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis, iron-driven oxidative reactions, and phospholipid peroxidation. TNBC, characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), is particularly prone to ferroptosis due to acyl-coenzyme A synthetase (ACSL) 4-related lipid changes and solute carrier family 7 member 11 (SLC7A11)-mediated cystine transport.

Enhancing stable and high-rate lithium ion storage through multifunctional molecular release in a phosphorus/carbon-bipyridine hybrid anode.

Phosphorus has emerged as a promising anode material due to its high specific capacity of 2594 mA h g and medium redox potential of about 0.7 V ( Li/Li). However, large volume changes and low ion reaction kinetics are still the dominant challenges that affect the long-term cycle stability and high-rate performance of phosphorus anodes.

Corrosion Resistance of Mn-Containing AFA Alloys in LBE at 550 °C with Controlled Oxygen Concentration of 10 wt.

Alumina-forming austenitic steels (AFA steels) exhibit excellent creep resistance and oxidation capabilities, making them a strong candidate for cladding materials in lead-cooled fast reactors. This study investigates the corrosion resistance of Mn-containing AFA steels in lead-bismuth eutectic (LBE) at 550 °C with a controlled oxygen concentration of 10 wt.%.

Phosphoproteomic Analysis of Maize Seedlings Provides Insights into the Mechanisms of Heat-Stress Tolerance.

The dramatically high temperatures triggered by global climate change threaten maize growth and yield. In recent years, increasing attention has focused on the impacts of heat injury on maize. However, the molecular mechanisms behind maize's adaptation to heat stress remain largely unexplored.

[Effect of electroacupuncture regulating BDNF/NRF2 signaling pathway on oxidative stress in dorsal root ganglion of rabbits with lumbar intervertebral disc degeneration].

Objectives: To observe the protective function and mechanism of electroacupuncture (EA) "Jiaji" (EX-B2) on dorsal root ganglion (DRG) in rabbits with pressure-induced lumbar intervertebral disc degeneration (IVDD).

Methods: Twenty-five male New Zealand rabbits with mature bones were divided into control, sham operation, model, EA, and acupuncture groups, with 5 rabbits in each group. The IVDD model was established by inserting kirschner wires to the vertebral bone surface between the lumbar (L) 4 and L5 vertebrae, followed by applying continuous axial pressure for 28 days.

A High-Modulus Dual-Cross-Linked Shell Promoting Phosphorus-Carbon Composites for Stable and High-Rate Lithium Ion Storage.

Phosphorus is considered an ideal anode material for lithium ion storage by virtue of its high theoretical capacity and moderate lithiation potential. However, issues such as large volume expansion of phosphorus leading to an electrical loss of contact and instability of the solid electrolyte interface hinder its practical performance. Improvement strategies that can effectively suppress volume expansion and provide stable electrical contacts are urgently needed.

The Effect of Heat Stress on Wheat Flag Leaves Revealed by Metabolome and Transcriptome Analyses During the Reproductive Stage.

In this study, we were dedicated to investigating the effect caused by heat stress on wheat flag leaves. Metabolome and transcriptome analysis were introduced to identify some key biological processes. As a result, 182 and 214 metabolites were significantly changed at the anthesis and post-anthesis stages, respectively; most of them were lipids, amino acids and derivatives, phenolic acids, and alkaloids.

Electroacupuncture regulates SIRT1/p53/p21 signaling pathway to prevent stress-induced premature senescence of nucleus pulposus cells in degenerative intervertebral discs.

Stress-induced premature senescence (SIPS) affects cellular functionality due to various stressors. In intervertebral disc degeneration (IVDD), nucleus pulposus (NP) cell dysfunction is crucial. Electroacupuncture (EA) has been used to alleviate low back pain and delay IVDD, but its potential mechanism is not yet well understood.

The Impact of on Oral and Systemic Health: A Comprehensive Review of Recent Research.

Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on.

Role of 3-mercaptopyruvate sulfurtransferase in cancer: Molecular mechanisms and therapeutic perspectives.

The occurrence and development of tumor is mediated by a wide range of complex mechanisms. Subsequent to nitric oxide and carbon monoxide, hydrogen sulfide (HS) holds the distinction of being the third identified gasotransmitter. Alternation of HS level has been widely demonstrated to induce an array of disturbances in important cancer cell signaling pathways.

Diverse Transient Chiral Dynamics in Evolutionary Distinct Photosynthetic Reaction Centers.

The evolution of photosynthetic reaction centers (RCs) from anoxygenic bacteria to higher-order oxygenic cynobacteria and plants highlights a remarkable journey of structural and functional diversification as an adaptation to environmental conditions. The role of chirality in these centers is important, influencing the arrangement and function of key molecules involved in photosynthesis. Investigating the role of chirality may provide a deeper understanding of photosynthesis and the evolutionary history of life on Earth.

Harnessing Defects in SnSe Film via Photo-Induced Doping for Fully Light-Controlled Artificial Synapse.

2D-layered materials are recognized as up-and-coming candidates to overcome the intrinsic physical limitation of silicon-based devices. Herein, the coexistence of positive persistent photoconductivity (PPPC) and negative persistent photoconductivity (NPPC) in SnSe thin films prepared by pulsed laser deposition provides an excellent avenue for engineering novel devices. It is determined that surface oxygen is co-regulated by physisorption and chemisorption, and the NPPC is attributed to the photo-controllable oxygen desorption behavior.

Hsa_circRNA_000166 accelerates breast cancer progression via the regulation of the miR-326/ELK1 and miR-330-5p/ELK1 axes.

Purposes: To probe the expression, clinical significance, roles, and molecular mechanisms of circRNA_000166 in breast cancer (BC).

Methods: Clinical tissue samples were gathered from 84 BC patients who underwent surgery at the Affiliated Hospital of Chengde Medical College. Clinical data were obtained from medical records and postoperative follow-up.

1D/2D Heterostructures: Synthesis and Application in Photodetectors and Sensors.

Two-dimensional (2D) semiconductor components have excellent physical attributes, such as excellent mechanical ductility, high mobility, low dielectric constant, and tunable bandgap, which have attracted much attention to the fields of flexible devices, optoelectronic conversion, and microelectronic devices. Additionally, one-dimensional (1D) semiconductor materials with unique physical attributes, such as high surface area and mechanical potency, show great potential in many applications. However, isolated 1D and 2D materials often do not meet the demand for multifunctionality.

Newcomers' perceptions of their experiences with oral health care in Canada and the United States.

Background: Recently, an increasing number of immigrants and asylum seekers and refugees (ASRs) have settled in both Canada and the United States. The poor oral health status prevalent among this population is a significant issue. Oral health professionals in both countries should understand newcomers' experiences with oral health care services to become more culturally competent.

Research PIV-based model on subsidence caused by coal mining.

The subsidence caused by coal mining could cause the destruction of roads and houses, and even the failure of infrastructures. Understanding of the mechanism of coal mining subsidence may provide early protecting to infrastructures on coming failure, but dynamic analysis of subsidence due to coal mining is currently needed. In this study we apply particle image velocimetry (PIV) method to reveal strata movement and subsidence according to the prototype and indoor physical model similarity experiment of Henan.

Promoting nitrogen-doped porous phosphorus spheres for high-rate lithium storage.

Phosphorus anode has shown great potential for the high-rate and high-energy-density lithium-ion batteries. Nevertheless, it still suffers from possible electrode cracking, ion-transport restrictions, and active-particle decomposition resulting from repeated alloying/de-alloying. To address the aforementioned issues, a nitrogen-doped flower-like porous phosphorus (f-P) sphere has been developed.

Heat shock factor ZmHsf17 positively regulates phosphatidic acid phosphohydrolase ZmPAH1 and enhances maize thermotolerance.

Heat stress adversely impacts plant growth, development, and grain yield. Heat shock factors (Hsf), especially the HsfA2 subclass, play a pivotal role in the transcriptional regulation of genes in response to heat stress. In this study, the coding sequence of maize ZmHsf17 was cloned.

Transient Chiral Dynamics in the Fenna-Matthews-Olson Complex Revealed by Two-Dimensional Circular Dichroism Spectroscopy.

Chirality plays a pivotal role across scientific disciplines with profound implications spanning light-matter interactions, molecular recognition, and natural evolutionary processes. This study delves into the active influence of molecular chirality on exciton energy transfer within photosynthetic protein complexes, focusing on the Fenna-Matthews-Olson (FMO) complex. Employing two-dimensional circular dichroism (2DCD) spectroscopy, we investigate the transient chiral dynamics of excitons during energy transfer processes within the FMO complex.