Survival and Clinicopathological Significance of CD47 in Human Solid Tumors: An Updated Systematic Reviews and Meta-Analysis.

Background: High expression levels of cluster of differentiation 47 (CD47) have been recognized as poor survival in several different cancers. Nevertheless, the significance of CD47 in patients with solid tumors remains controversial.

Aims: The objective of this study is to elucidate whether elevated CD47 expression independently predicts a poor prognosis across solid tumors through pooled survival and clinicopathological analyses.

Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells.

Background: Porcine Circovirus 2 (PCV2) vaccination plays a crucial role in preventing porcine circovirus-associated disease (PCVAD). Nevertheless, pig farms face significant challenges in evaluating vaccination efficacy due to the inability of PCV2 vaccines to achieve sterilizing immunity and the variability among vaccine manufacturers. These challenges are further compounded by the limitations of conventional antibody detection methods, which fail to distinguish between maternally-derived antibodies (MDAs) and vaccine-induced antibodies.

The propagation characteristics of seismic waves in ultra-deep overburden by large-scale shaking table test.

The seismic performance of earth-rock dams on deep overburdens has long been a central focus in dam engineering. Understanding the propagation law of seismic waves within a deep overburden is key to revealing the mechanisms of the dynamic response. In this study, the propagation characteristics of horizontal and vertical seismic waves in a deep overburden were systematically investigated using large-scale shaking table tests, with analysis based on acceleration and pore pressure data combined with stockwell transforms and coherence function methods.

Case Report: Intraoperative endoscopic treatment for the "pseudo" lumen formation of jejuno-esophageal anastomosis in laparoscopic total gastrectomy.

Recently, the incidence of adenocarcinoma of esophagogastric junction (AEG) is increasing in China. Laparoscopic total gastrectomy plus D2 lymph node dissection is an important treatment method for AEG of Siewert type II. In order to achieve the esophagojejunostomy, surgical techniques, no matter in open surgery or in laparoscopic one, are highly demanding.

The natural variation allele OsGSW3.2 in Oryza rufipogon is involved in brassinosteroid signaling and influences grain size and weight.

Oryza rufipogon is the ancestor of cultivated rice and harbors many elite genes; thus, this plant is an important germplasm for improving rice varieties. Grain size is an important factor in determining rice yield and quality. In this study, we identified a natural variation allele from the O.

Cytological observation and transcriptome analysis reveal that NTFR1 is a new tetraploid rice fertility gene using the tetraploid fertility-directed lines.

Neo-tetraploid rice, a type of high-fertility tetraploid rice, is thought to be a useful material for utilizing its heterosis. However, the mechanism of its high fertility remains little known. Here, two tetraploid fertility-directed lines were generated and used to evaluate their variation on fertility charts.

Convective injection into stratospheric intrusions alters the tropopause chemical structure.

The tropopause chemical structure (TCS) is influenced by stratosphere-troposphere exchange (STE) and plays a role in the Earth's climate. However, this role is still not fully understood in East Asia, where active STE and high anthropogenic emissions coexist. Using airborne measurements of trace gases, including O, CO, and HO, we reveal the variations in TCS during two consecutive cut-off lows (COLs), an important trigger of STE.

Improving Hair Scar Defects Through the Integration of Autologous Fat Transplantation and Hair Follicle Unit Transplantation.

Objective: To assess the clinical efficacy of combining autologous fat grafting with hair follicle unit transplantation.

Methods: The authors conducted a retrospective analysis involving 30 patients at the Department of Plastic Surgery, Second Affiliated Hospital of Nanchang University, between January 2021 and January 2023. Granular fat was harvested from the thigh's posterior aspect using liposuction.

Remote sensing research on plastics in marine and inland water: Development, opportunities and challenge.

The accumulation of plastic waste from various sources into marine and inland water is considered a global problem due to its serious impacts on aquatic ecosystems and human health. In the past decade, remote sensing has played an important role in monitoring of plastic pollution in marine and inland water sources and has achieved a series of research results in this field. In this study, a comprehensive review was conducted on the development, opportunities, and challenges of datasets and methods in Marine and Inland Water Plastics Remote Sensing (MIWPRS) monitoring over the past decade, based on the Web of Science (WOS) core database.

Rice BARENTSZ genes are required to maintain floral developmental stability against temperature fluctuations.

BARENTSZ (BTZ), a core component of the exon junction complex, regulates diverse developmental processes in animals. However, its evolutionary and developmental roles in plants remain elusive. Here, we revealed that three groups of paralogous BTZ genes existed in Poaceae, and Group 2 underwent loss-of-function mutations during evolution.

In vitro efficacy of Rosa damascena solid state fermentation liquid and water extract on skin care.

Background: As a medicinal and food homologous plant, Rosa damascena is not only highly ornamental, but also rich in a variety of active ingredients such as polyphenols and flavonoids. It is widely used in cosmetics, food and pharmaceutical industries.

Objective: To study the in vitro efficacy of Rosa damascena solid state fermentation liquid (RDF) and water extract (RDE).

Significance of Nutritional-Inflammatory Index as Predictors for Total Neoadjuvant Therapy-Induced Tumor Regression in Locally Advanced Rectal Cancer Patients.

Purpose: To evaluate the predictive capacity of the nutritional-inflammatory index and clinicopathological characteristics in patients with locally advanced rectal cancer (LARC) receiving total neoadjuvant therapy (TNT).

Methods: Data from 127 patients with LARC receiving TNT from January 2017 to January 2021 were retrospectively analyzed. Clinicopathological characteristics with different TNT-induced responses were compared.

Laparoscopic versus open gastrectomy for nonmetastatic T4a gastric cancer: a meta-analysis of reconstructed individual participant data from propensity score-matched studies.

Background: ​The applicability of laparoscopy to nonmetastatic T4a patients with gastric cancer remains unclear due to the lack of high-quality evidence. The purpose of this study was to compare the survival rates of laparoscopic gastrectomy (LG) versus open gastrectomy (OG) for these patients through a meta-analysis of reconstructed individual participant data from propensity score-matched studies.

Methods: PubMed, Embase, Web of Science, Cochrane library and CNKI were examined for relevant studies without language restrictions through July 25, 2023.

Prognostic value of the advanced lung cancer inflammation index in patients with gastric cancer after radical gastrectomy: a propensity-score matching cohort study and meta-analysis.

Background: Insufficient evidence existed about the prognostic role of the advanced lung cancer inflammation index (ALI) for gastric cancer patients who underwent curative resection. The aim of this study was to identify the predictive ability of ALI for survival after curative gastrectomy.

Methods: We retrospectively analyzed 328 gastric cancer patients who received curative gastrectomy from the database of Chongqing University Cancer Hospital, and investigated the prognostic role of the preoperative ALI compared with clinicopathological variables and other serum biomarkers, such as preoperative neutrophil-to-lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and Lymphocyte-monocyte ratio (LMR).

OsmiR5519 regulates grain size and weight and down-regulates sucrose synthase gene RSUS2 in rice (Oryza sativa L.).

The up-regulation of OsmiR5519 results in the decrease of grain size, weight and seed setting rate. OsmiR5519 plays important roles in the process of grain filling and down-regulates sucrose synthase gene RSUS2. MicroRNAs (miRNAs) are one class of small non-coding RNAs that act as crucial regulators of plant growth and development.

Identification of important gene signatures in schizophrenia through feature fusion and genetic algorithm.

Schizophrenia is a debilitating psychiatric disorder that can significantly affect a patient's quality of life and lead to permanent brain damage. Although medical research has identified certain genetic risk factors, the specific pathogenesis of the disorder remains unclear. Despite the prevalence of research employing magnetic resonance imaging, few studies have focused on the gene level and gene expression profile involving a large number of screened genes.

The potential of Paeonia lactiflora pall seeds oil as a pure natural cosmetics raw material: In Vitro findings.

Background: As a traditional Chinese herbal medicine, Paeonia lactiflora Pall is rich in various active ingredients such as polysaccharides and total flavonoids while having ornamental value. It has potential application value in the development of food and cosmetics.

Objective: To study the in vitro efficacy of Paeonia lactiflora Pall seeds oil.

Injectable, Adhesive Albumin Nanoparticle-Incorporated Hydrogel for Sustained Localized Drug Delivery and Efficient Tumor Treatment.

Injectable hydrogels are receiving increasing attention as local depots for sustained anticancer drug delivery. However, most current hydrogel-based carriers lack tissue-adhesive ability, a property that is important for the immobilization of drug-loaded systems at tumor sites to increase local drug concentration. In this study, we developed a paclitaxel (PTX)-loaded injectable hydrogel with firm tissue adhesion for localized tumor therapy.

Plum blossom low molecular weight polypeptide protects HaCaT cells against UVB-induced oxidative damage in vitro and underlying mechanism.

Background: Increasing amounts of ultraviolet radiation occur as ozone depletion causes the earth's ozone layer to be destroyed, making antioxidant efficacy a research hotspot. Previous studies on plum blossom have mostly focused on Volatile Oils, Flavonoids, Phenylpropanoids, and other compounds, whereas few studies have focused on low molecular weight polypeptide (LMWP) of plum blossom. This research provides a reference for the deep processing and utilization of plum blossom.

OsmiRNA5488 Regulates the Development of Embryo Sacs and Targets in Rice ( L.).

Small RNAs are a class of non-coding RNAs that typically range from 20 to 24 nucleotides in length. Among them, microRNAs (miRNAs) are particularly important regulators for plant development. The biological function of the conserved miRNAs has been studied extensively in plants, while that of the species-specific miRNAs has been studied in-depth.