Immunoglobulin G4-Related Inflammatory Pseudotumor With Cystic Features Mimicking Renal Cancer.

Introduction: Immunoglobulin G4-related disease is a systemic fibroinflammatory disorder that affects the kidney, presenting as an immunoglobulin G4-related inflammatory pseudotumor. These renal inflammatory pseudotumors are usually solid, and cystic presentations have not been previously described.

Case Presentation: We report a 77-year-old man who presented with a Bosniak category III renal cystic mass and periaortic fibrous thickening.

A Case of Drug-Induced Hypersensitivity Syndrome Caused by Apalutamide.

Introduction: Apalutamide, an androgen receptor antagonist for prostate cancer, rarely causes drug-induced hypersensitivity syndrome (DIHS).

Case Presentation: A 75-year-old male with prostate cancer and multiple bone metastases developed grade 2 rash and grade 3 liver dysfunction according to the Common Terminology Criteria for Adverse Events (CTCAE) 3 weeks after starting apalutamide with a GnRH antagonist, followed by a 3-day fever. Ten days later, symptoms worsened to grade 3 rash and grade 4 liver dysfunction.

Effect of balloon angioplasty on inframalleolar stenosis in patients with chronic limb-threatening ischemia.

Background: Although there are reports on angioplasty for inframalleolar (IM) occluded lesions in chronic limb-threatening ischemia (CLTI), the clinical outcomes specific to the IM stenotic lesions remain unclear. This study evaluated the effect of balloon angioplasty for IM stenotic lesions on the clinical outcomes of patients with CLTI.

Methods: This is a multicenter, retrospective, nonrandomized observational study.

[Fournier's Gangrene with M1UK-Lineage Streptococcus Pyogenes Infection : A Case Report].

A 37-year-old man with a history of chronic myeloid leukemia presented to our hospital with fever and right scrotal pain. Computed tomography (CT) revealed subcutaneous fluid in the soft tissues of the scrotum and penis. His white blood count was 3,700/μl and C-reactive protein (CRP) was 44.

Selective visceral perfusion in thoracoabdominal aortic surgery: optimal flow rate in a porcine model.

To determine the optimal perfusion volume for the celiac artery (CA) and superior mesenteric artery (SMA) in a porcine model. Fifteen Yorkshire pigs (46.7 ± 5.

Structural control of μ-hydroxo-μ-peroxodicobalt(III) complex with the 6-hpa dinucleating ligand to enhance O-evolution activity in catalytic water oxidation.

The 6-hpa ligand forms a μ-hydroxo-μ-peroxodicobalt(III) complex [Co(μ-OH)(μ-O)(6-hpa)]X (X = ClO (1a) and PF (1b)) and controls the formation of configuration. Electrochemical studies revealed that the 6-hpa ligand lowers the oxidation potential of the peroxide moiety by 0.13 V and twice enhances O evolution during catalytic water oxidation by fixing the configuration.

Association Between Dreams, Anxiety, and Depressive Symptoms Among Japanese Adolescents: A Cross-Sectional Study.

Worsening adolescent mental health is a significant social issue. Although dreams may reflect one's mental state, few studies have focused on adolescents. Therefore, this study investigated the relationship between dream content and mental health, specifically anxiety disorder and depressive symptoms, among Japanese adolescents.

Strontium and barium in deciduous teeth and infant feeding methods: A birth cohort adjunct study to the Japan environment and children's study.

Deciduous teeth are a unique medium that record exposure to various elements over time, as they are formed during fetal and infantile periods. We aimed to evaluate the association between infant feeding methods and changes in the distribution of Barium (Ba) and Strontium (Sr) in deciduous teeth of children. The current analysis included 216 children around 6-7 years of age whose deciduous central incisor teeth were provided between March 2018 and February 2020, as an adjunct study of the Japan Environment and Children's study.

Fanconi syndrome induced by red yeast rice supplement.

Fanconi syndrome is a disorder of the proximal renal tubules characterized by metabolic acidosis, renal glycosuria, and aminoaciduria. Recently, Fanconi syndrome caused by red yeast rice supplements has been reported. We encountered a 60-year-old woman with acute kidney injury and Fanconi syndrome caused by a red yeast rice supplement.

Longitudinal Effects of Remote Work Frequency on Insomnia Symptoms and Short Sleep Duration Among Japanese Workers.

Remote work has been established as a method of working. However, the impact of remote work on employees' sleep health has not been elucidated. This study aimed to examine the longitudinal association between the frequency of remote work and sleep problems among workers in Japan.

Transcriptomic resource and hormonal profiling of the smut fungus, Ustilago esculenta, coexisting with Zizania latifolia and forming Makomotake.

Ustilago esculenta is a smut fungus that parasitizes Zizania latifolia, forming edible fungal galls known as Makomotake. In this study, we quantified indole-3-acetic acid (IAA) produced in liquid-cultured U. esculenta and in fungal galls at different growth stages.

Impact of Hemodialysis Duration on Arterial Characteristics and Patient Outcomes following Endovascular Therapy for Inframalleolar Occlusive Disease: Results from the MAVERICK Study.

Purpose: To evaluate the effect of hemodialysis (HD) in a medical history of patients with inframalleolar (IM) occlusive disease following balloon angioplasty for de novo occluded IM lesions, specifically focusing on the clinical outcomes related to their HD history.

Materials And Methods: The study had a multicenter, retrospective, nonrandomized, observational design and was performed at 4 cardiovascular centers in Japan. Patients aged ≥20 years with chronic limb-threatening ischemia (CLTI) (Rutherford Classification 5-6) who were treated with endovascular therapy for de novo IM occlusions between January 2016 and December 2022 were included.

Nodal Lymphangiography and Embolization for Postoperative Lymphatic Leakage.

Intranodal lymphangiography has replaced conventional pedal lymphangiography and has advanced lymphatic intervention. In this method, a lymph node is punctured and Lipiodol is injected to visualize the subsequent lymphatic vessels. This has facilitated the widespread adoption of lymphatic interventional radiology due to the simplicity of the technique and the shortened examination time of the procedure, which allows easy mapping of lymphatic vessels and lymphatic fluid dynamics.

Associations between Clustered Visual Field Progression and Locations of Disc Hemorrhages in Glaucoma: A 3-Year Prospective Study.

Purpose: To evaluate the impact of disc hemorrhages (DHs) at different locations on clustered visual field (VF) progression in patients with primary open-angle glaucoma (POAG) over a 3-year prospective study.

Design: A prospective multicenter cohort study.

Participants: Patients diagnosed with POAG and intraocular pressure (IOP) ≤18 mmHg undergoing prostaglandin analog monotherapy.

Enhancement of Sensitivity in Aggregation-Based Whole-Cell Arsenite Sensor Utilizing Arsenic Metabolism Regulation.

Arsenite [As(III)] is a toxic substance widely present on Earth, and the development of low-cost and simple microbial-based As(III) sensors has been attracting attention. Recently, we discovered that the protein LuxR, which contains multiple cysteine residues with high affinity for As(III), forms an insoluble structure upon binding to As(III) and exhibits OFF-switching properties as a quorum sensing transcriptional activator. Based on this property, the LuxR sensor operates on a new principle distinct from conventional whole-cell As(III) sensors; however, its sensitivity remains a challenge.

Efficacy and safety of atrial fibrillation ablation in patients aged ≥80 years: a retrospective study.

Catheter ablation is the first-line treatment for atrial fibrillation. Although the efficacy and safety of this procedure have been reported in older patients, they might diminish with age. Therefore, this study aimed to determine the safety and effectiveness of atrial fibrillation ablation in patients aged ≥80 years.

Percutaneous transhepatic vascular embolization for a mesenteric arteriovenous malformation leading to decreased portal pressure in a patient with alcoholic liver cirrhosis: A case report.

Arteriovenous malformations in the abdominal region are rare, and they are known to occasionally cause portal hypertension. A 66-year-old man with a chief complaint of fatigue and blood tests showing hepatic dysfunction was seen for a more detailed examination. Abdominal contrast-enhanced computed tomography showed an anastomosis of the ileal artery and ileal vein via a nidus within the mesentery.

Evaluation of elemental impurities and particle size distribution in nanomedicine using asymmetric flow field-flow fractionation hyphenated to inductively coupled plasma mass spectrometry.

Nanomedicines, which consist of nanoparticles as active ingredients, have been developed and approved for pharmaceutical use. However, no method has been established to quantify ions and nanoparticles containing the same elements separately. We developed an asymmetric flow field-flow fractionation hyphenated to inductively coupled plasma mass spectrometry (AF4-ICP-MS) to assess elemental impurities from ions and nanoparticles of different sizes.

Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein.

The arsenic trioxide (ATO)-based cure of acute promyelocytic leukemia is attributed to PML/RARα oncoprotein degradation through binding of its RBCC domain (i.e., consist of RING, B-box1, B-box2, and Coiled-coil) with arsenic.

Classification of intrusive thought patterns based on differences in the mechanisms of occurrence and persistence.

Introduction: Intrusive thoughts occurring independently of intention are symptoms of obsessive-compulsive disorders (OCD). However, they also appear in various other disorders, including substance use disorders, depression, post-traumatic stress disorder, and anxiety disorders, as well as in healthy individuals. Despite this, the diversity of intrusive thoughts remains largely unexplored.

Effect of oxytocin and cloprostenol on the seminal parameters of red brocket deer () during the electroejaculation procedure.

Successful implementation of conservation programs for endangered species requires biological material for use in reproductive biotechnologies. This enhances reproductive efficiency and helps increase the populations of critically endangered species. One way to facilitate the exchange of genetics between captive and free-ranging animals is through the creation of cryogenic banks that store cryopreserved gametes.

The polar-localized borate exporter BOR1 facilitates boron transport in tapetal cells to the developing pollen grains.

Boron is an essential micronutrient required for plant cell wall integrity, as it is necessary for crosslinking the pectic polysaccharide rhamnogalacturonan II. Reproductive organs require a greater amount of boron for development and growth compared with vegetative organs. However, the mechanism by which plants distribute boron to specific organs is not fully understood.

Effect of structural bending on the photophysical properties of perylene bisimide.

The effect of nonplanarity on the electronic properties of π-systems has been difficult to study systematically because of the limited availability of suitable model compounds. Our group recently synthesized a series of end-to-end bent perylene bisimide (PBI) cyclophanes, whose degree of bending is adjustable by modifying the internal alkyl tethers. Herein, we subjected these bent PBI derivatives to theoretical calculations and time-resolved spectroscopy.

Analysis of the Fossilization Processes of Shells Using Raman Micro-Mapping Combined with Principal Component Analysis and Partial Least Squares Regression.

Micro-Raman spectroscopic analysis of a fossil sample of was performed to investigate the chemical process of fossilization. The sample, originating from the Miocene Katsuta Group, Okayama prefecture, southwestern Japan, had a conical shell body with multiple protuberances on the outer layer. The interior of the shell was filled with a carbonate sediment.