Ab interno removal of malpositioned ex-press glaucoma device combined with bleb needling.

Purpose: We present an ab interno removal technique combined with a needling procedure for a malpositioned Ex-PRESS glaucoma shunt.

Study Design: Retrospective case series.

Methods: This study examined four cases of malpositioned Ex-PRESS shunts.

Associations between Clustered Visual Field Progression and Locations of Disc Hemorrhages in Glaucoma: A 3-Year Prospective Study.

Purpose: To evaluate the impact of disc hemorrhages (DHs) at different locations on clustered visual field (VF) progression in patients with primary open-angle glaucoma (POAG) over a 3-year prospective study.

Design: A prospective multicenter cohort study.

Participants: Patients diagnosed with POAG and intraocular pressure (IOP) ≤18 mmHg undergoing prostaglandin analog monotherapy.

Exploration of the cutoff values of axial length that is susceptible to develop advanced primary open angle glaucoma in patients aged less than 50 years.

Purpose: To examine the correlation of the spherical equivalent refraction (SER) and axial length with the visual field, and to determine cutoff values of SER and axial length for the risk of developing advanced primary open-angle glaucoma (POAG).

Methods: Patients with POAG or secondary glaucoma were retrospectively enrolled from a clinical database at Kyoto University Hospital between August 2011 and December 2018. Correlations between the mean deviation (MD) and axial length were evaluated in these patients using the Pearson's correlation coefficient.

Relationships of the Duration from Onset and Macular Morphology with Metamorphopsia After Surgery for Macula-Off Rhegmatogenous Retinal Detachment.

Purpose: To investigate the relationships among postoperative metamorphopsia and postoperative macular morphological changes and the duration from the onset of visual field disturbance to surgery (DVD) in patients who underwent surgery for macula-off rhegmatogenous retinal detachment (RRD).

Patients And Methods: We retrospectively reviewed 33 eyes of 33 patients who underwent pars plana vitrectomy (PPV) for macula-off RRD with known onset of symptoms of visual field disturbance at Niigata University Medical and Dental Hospital or Saiseikai Niigata Hospital and were followed up for at least 6 months postoperatively. Optical coherence tomography images of the macula obtained at 6 months postoperatively and DVD were analyzed, and the associations of the DVD with vertical metamorphopsia (vM) and horizontal metamorphopsia (hM) at 6 months postoperatively were evaluated using M-CHARTS.

Correlation between contrast sensitivity and national eye institute visual function questionnaire (NEI VFQ-25) Rasch scores in patients with open-angle glaucoma: A cross-sectional study.

Background: We examined the relationship between contrast sensitivity (CS) and visual field stage/severity in patients with open-angle glaucoma (OAG), and correlated CS with Quality of Vision (QOV) scores.

Methods: CS was measured under photopic (100 cd) and mesopic (10 cd) conditions in 218 eyes of 109 patients with OAG aged < 60 years. The glaucoma stages were divided into four groups according to the mean deviation (MD) of the Humphrey Field Analyzer (HFA) 24 - 2 or 10 - 2 Swedish Interactive Thresholding Algorithm (SITA) standard, and their relationship with CS was examined.

Effect of Ripasudil on the Change Rates of the Circumpapillary Retinal Nerve Fiber Layer Thickness in Patients With Primary Open-Angle Glaucoma.

The effect of the Rho-kinase inhibitor ripasudil on the retinal optic nerve fiber layer (RNFL) remains unclear. We aimed to determine this effect in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT) measurements and linear mixed analysis. This study prospectively included outpatients from a single center with POAG without a history of vitreoretinal or glaucoma surgery from December 2014 to June 2020, in whom the circumpapillary RNFL thickness (cpRNFLT) was measured more than three times before and after ripasudil initiation, without additional medication or surgery during the period.

Comparison of a Novel Head-Mounted Objective Auto-perimetry (Gaze Analyzing Perimeter) and Humphrey Field Analyzer.

Purpose: To evaluate the agreement between 24-2 visual field (VF) test results obtained using the gaze analyzing perimeter (GAP; Findex) and the Humphrey field analyzer (HFA; Carl Zeiss Meditec).

Design: Cross-sectional study.

Participants: Patients underwent HFA 24-2 for suspected or confirmed VF loss and were treated at the Kyoto University Hospital between December 2022 and July 2023.

Intrascleral intraocular lens fixation with ab interno trabeculotomy in patients with exfoliation glaucoma with lens subluxation.

Purpose: To evaluate the surgical outcomes of intrascleral intraocular lens (IOL) fixation using ab interno trabeculotomy (LOT) in patients with exfoliation glaucoma with lens subluxation.

Study Design: Retrospective case series.

Methods: Twenty eyes of 18 patients with exfoliation glaucoma and lens or IOL subluxations were included.

A novel bleb revision technique: lining with tenon's patch graft for treatment of large, ischemic, leaking blebs with severe conjunctival scarring after trabeculectomy.

Purpose: We report a new bleb lining technique with Tenon's patch graft for late-onset leakage from large ischemic bleb with severe conjunctival scarring and impractical conjunctival mobilization after trabeculectomy.

Study Design: Retrospective case series.

Methods: This study includes six cases with late-onset leakage from large ischemic blebs.

Parapapillary choroidal microvasculature dropout in eyes with primary open-angle glaucoma.

The purpose of this study was to evaluate how various parameters are related to microvasculature dropout (MvD) area measured using optical coherence tomography angiography (OCTA). We measured the area of MvD in 55 patients with primary open-angle glaucoma (POAG). Using OCTA, MvD area and peripapillary choroidal atrophy (PPA) area were assessed in a 4.

Measurement of vitreous humor pressure in vivo using an optic fiber pressure sensor.

We conducted a study to assess the pressure difference between the aqueous and vitreous humors in rabbit eyes using a direct intraocular pressure (IOP) measurement method. A micro-optic-fiber pressure sensor was utilized for this purpose. Preliminary experiments with enucleated porcine eyes confirmed the sensor's accuracy in measuring both aqueous and vitreous humor pressure.

Surgical safety and efficacy of a multi-stent system, the comet stent, in Baerveldt glaucoma implant surgery: a prospective pilot study.

Purpose: This study aimed to introduce a new technique for lowering intraocular pressure (IOP) using a multi-stent system after the implantation of a Baerveldt glaucoma implant (BGI) and evaluate its clinical effectiveness.

Study Design: Prospective case series.

Methods: Six patients with uncontrolled refractory glaucoma were enrolled between December 2021 and May 2022.

Relationship between Inter-Eye Asymmetries in Corneal Hysteresis and Visual Field Severity in Patients with Primary Open-Angle Glaucoma.

This study investigated the influence of asymmetric corneal hysteresis (CH) on asymmetric visual field impairment between right and left eyes in patients with primary open-angle glaucoma (POAG) without a history of intraocular surgery. CH, corneal resistance factor (CRF), and corneal compensated intraocular pressure (IOPcc) were measured using the Ocular Response Analyzer. Differences between the eyes (right eye-left eye: DIF) and CH-based and in target parameters (higher CH eye-lower CH eye: DIF) were calculated in the same patient.

Noninferiority of Microhook to Trabectome: Trabectome versus Ab Interno Microhook Trabeculotomy Comparative Study (Tram Trac Study).

Purpose: To elucidate the noninferiority of ab interno microhook trabeculotomy (μTLO) using a recently developed reusable stainless spatula-type microhook device to incise the trabecular meshwork to Trabectome (Neomeix, Inc) surgery in terms of the 1-year postoperative outcomes of Japanese patients with glaucoma by means of propensity score analyses.

Design: Multicenter, retrospective cohort study.

Participants: We enrolled 553 and 392 patients who underwent Trabectome surgery and μTLO, respectively, between January 2014 and March 2020 at 10 facilities.

Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography.

Purpose: The purpose of this study was to image and investigate the foveal microstructure of human cone and Müller cells using adaptive optics-optical coherence tomography.

Methods: Six healthy subjects underwent the prototype adaptive optics-optical coherence tomography imaging, which allowed an axial resolution of 3.4 µm and a transverse resolution of approximately 3 µm.

Successful Treatment of Post-Phacoemulsification Descemet's Membrane Detachment Assessed by Anterior Segment Optical Coherence Tomography: A Case Report.

Descemet's membrane detachment (DMD) is a rare but serious complication of phacoemulsification surgery. A small DMD may resolve spontaneously, but extensive DMD often requires intracameral injection of air, nonexpansile gases, or expansile gases. A 92-year-old man who underwent phacoemulsification and aspiration with intraocular lens placement in the right eye had significantly reduced visual acuity, with a hazy cornea after surgery.

Macular Cone Abnormalities in Behçet's Disease Detected by Adaptive Optics Scanning Light Ophthalmoscope.

Background And Objective: Investigations of morphological changes in photoreceptors in Behçet's disease (BD) using adaptive optics scanning light ophthalmoscope (AOSLO) are lacking. The authors aimed to evaluate macular cone density and regularity in BD patients with or without a history of uveitis with good visual acuity (VA).

Patients And Methods: The authors included 16 patients (29 eyes) with BD and 12 healthy volunteers (12 eyes) as controls.