Effects of aerobic exercise on executive function in children and adolescents with attention deficit hyperactivity disorder: a systematic review and meta-analysis of randomized controlled trials.

Background: The benefits of aerobic exercise on the executive function of children and adolescents have been confirmed to a certain extent. However, the effects of such interventions on the executive function of children and adolescents with attention deficit hyperactivity disorder (ADHD) require further exploration. This study is a systematic review of randomized controlled trials (RCTs) of aerobic exercise interventions for children and adolescents with ADHD, aiming to provide valuable intervention suggestions to enhance the executive function of children and adolescents with ADHD.

Research Advance in the Development of Antimicrobial Peptides Using Deep Learning.

As the global issue of antibiotic resistance becomes increasingly severe, antimicrobial peptides (AMPs), a class of short-chain peptides with broad-spectrum antibacterial activity, have garnered significant attention from the scientific community due to their unique antibacterial properties and potential clinical applications. However, traditional methods for discovering and designing AMPs often rely on repetitive laboratory trials and error corrections, which are not only costly but also inefficient. In contrast, the application of artificial intelligence (AI) technology, particularly deep learning algorithms, for screening and predicting AMPs has demonstrated substantial advantages.

Copper immobilization and resource recovery from acidic copper mine water based on algae and bioelectrochemical system.

Acidic copper mine water, characterized by its organic matter scarcity, low pH, and high Cu pollution, presents major challenges due to limitations in traditional biological treatment and the high costs of physicochemical methods. There is an urgent need for an efficient treatment and resource recovery process. Algae could adsorb and immobilize Cu, and the secondary metabolic organics could be metabolized by bacteria, which compensates for the shortcomings of algae.

Electrocatalytic C─S Cross-Coupling via Engineered Frustrated Lewis Acid-Base Pairs for High-Efficiency Methanesulfonate Synthesis.

The electrochemical synthesis of sulfonyl compounds under mild conditions remains a significant challenge due to the reliance on harsh reagents, high energy consumption, and low selectivity in conventional methods. Herein, we report a novel strategy for efficient C─S bond formation through in situ modulation of frustrated Lewis acid-base pairs within a copper-based metal-organic framework (CuBDC-XN). By precisely engineering electron-deficient Cu Lewis acid sites and electron-rich XN-functionalized Lewis base sites, this bifunctional catalyst enables the synergistic co-reduction of SO and CO into methanesulfonate (MS) at ambient conditions with a Faradaic efficiency of 13.

A Related Foodborne Diarrhea Outbreak in an Elderly Care Center - Beijing Municipality, China, May 2024.

What Is Already Known About This Topic?: is a gram-positive, anaerobic, spore-forming bacillus widely distributed in the environment. Enterotoxin-producing strains of can cause foodborne diarrheal outbreaks in humans, with incubation periods typically ranging from 2 to 36 hours.

What Is Added By This Report?: Investigation identified 98 cases aged 22-99 years.

Non-piezoelectric SiO amorphous nanomaterials for highly tribocatalytic water purification.

Being widely available in the earth's rock layers, SiO is among the earth's most thoroughly distributed natural mineral resources. Here, non-piezoelectric amorphous SiO mineral nanoparticles have been experimentally designed for efficient tribocatalytic dye degradation under mechanical friction provided by 400-1200 rpm low-velocity stirring. The friction between the catalyst surface and the stirring rod leads to the generation of positive and negative charges, which react with hydroxide and oxygen, respectively, in the dye solution to produce some active substances, resulting in tribocatalytic organic dye degradation.

NRN1 may Modulate Tau Phosphorylation and Neuronal Apoptosis in AD the PIGU-CASP3 Axis.

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by hyperphosphorylation of tau protein to form neurofibrillary tangles (NFTs) and amyloid β (Aβ) deposition to form senile plaques, and its specific regulatory mechanism remains incompletely understood. Neurotrophic factors (NTFs) play important roles in neuronal growth, differentiation, and survival, and are considered to have potential therapeutic effects in AD.

Objective: This study aimed to investigate the effects of NTFs on tau protein phosphorylation in AD and its underlying mechanisms.

Multifunctional nanocomposite hydrogels: an effective approach to promote diabetic wound healing.

Diabetes, a metabolic disease that is becoming increasingly severe globally, presents a significant challenge in the medical field. Diabetic wounds are characterized by their chronicity, difficulty healing, and complex microenvironment that harbors multiple adverse factors, including elevated hyperglycemia, persistent inflammation, susceptibility to infections, and oxidative stress, all of which contribute to the impaired healing process. Nanocomposite hydrogels, as materials with unique physicochemical properties and biocompatibility, have gained growing attention in recent years for their potential applications in diabetic wound healing.

Causal association between dietary factors and telomere length revealed by mendelian randomization.

Observational studies have reported associations between dietary factors and telomere length. However, the inherent limitations of observational study designs render them susceptible to confounding and reverse causation biases. Therefore, this study aims to explore the association between dietary factors and telomere length using Mendelian Randomization (MR) to minimize the influence of confounding factors and reverse causality.

How does uncertainty avoidance affect employee voice behavior through the dual-path ways of work engagement and psychological security?

Individual traits may have an important impact on employee voice behavior. Considering the different purposes and potential risk exposure of promotive/prohibitive voice, this study constructs a two-path model of the effect of uncertainty avoidance on employee promotive/prohibitive voice based on the Uncertainty Management Theory, examining the mediating roles of work engagement and psychological security, as well as the moderating role of empowering leadership. Through a survey of 417 Chinese employees, the results show that (1) Uncertainty avoidance positively affects promotive voice through work engagement; (2) Uncertainty avoidance negatively affects prohibitive voice through psychological security; (3) Empowering leadership moderates the mediating role of work engagement in the relationship between uncertainty avoidance and promotive voice, and high-level empowering leadership significantly enhances the indirect effect of work engagement and strengthens the relationship between uncertainty avoidance and promotive voice; (4) Empowering leadership fails to moderate the relationship between uncertainty avoidance and psychological security.

Molecular Engineering of Alginate Lyases and the Potential Agricultural Applications of Their Enzymatic Products.

Alginate lyases, enzymes that degrade alginate into unsaturated oligosaccharides, have attracted significant attention for their potential applications across various fields, particularly in agriculture. This review focuses on the molecular engineering of alginate lyases to enhance their activity, stability, and specificity as well as the agricultural applications of the resulting enzymatic products, known as alginate oligosaccharides (AOS). We start by summarizing the sources and classification of alginate lyases, followed by recent advances in their engineering through directed evolution, rational design, truncation of noncatalytic domains, and conserved domain reconstruction.

The effect of zopiclone co-administration on sertraline initial dosage optimization in pediatric major depressive disorder patients based on model-informed precision dosing.

Objective: The present study aims to explore the initial dosage optimization of sertraline in pediatric major depressive disorder (MDD) patients based on model-informed precision dosing (MIPD).

Methods: A total of 111 pediatric MDD patients treated with sertraline were included for analysis using MIPD. Sertraline concentration levels, physiological and biochemical indexes of pediatric MDD patients, combined drug information were included in the construction of model.

A Gaussian convolutional optimization algorithm with tent chaotic mapping.

To solve the problems of the traditional convolution optimization algorithm (COA), which are its slow convergence speed and likelihood of falling into local optima, a Gaussian mutation convolution optimization algorithm based on tent chaotic mapping (TCOA) is proposed in this article. First, the tent chaotic strategy is employed for the initialization of individual positions to ensure a uniform distribution of the population across a feasible search space. Subsequently, a Gaussian convolution kernel is used for an extensive depth search within the search space to mitigate the likelihood of any individuals converging to a local optimum.

Yogurt consumption and risk of accelerated aging: A population-based study from the NHANES 2003-2006.

Introduction: Yogurt consumption is beneficial to health, but its association with aging remains unclear. This study aims to explore the relationship between yogurt consumption and aging using data from the 2003-2006 National Health and Nutrition Examination Survey (NHANES).

Methods: We used data from 4,056 participants to examine the relationship between yogurt consumption and aging.

One-step hydrothermal synthesis of CQDs/TiO/NH-MIL-125 for efficient photocatalytic production of HO under visible light.

NH-MIL-125 and its derivatives are receiving more attention in various aspects of photocatalytic reactions, especially in the photocatalytic hydrogen peroxide (HO) production from water (HO) and oxygen (O), which is a promising and sustainable strategy. However, the generation of HO from NH-MIL-125 is far from satisfactory due to rapid photo-generated carriers recombination and poor surface electron transfer. In the work, the composite photocatalyst CQDs/TiO/NH-MIL-125 (C/T/NM) was designed for the first time by one-step hydrothermal method.

Evaluation of Dexmedetomidine with Tiletamine-Zolazepam for Snow Leopard (Panthera uncia) Immobilization.

This study describes two different doses of dexmedetomidine combined with tiletamine-zolazepam (TZ) for anesthesia in snow leopards (Panthera uncia). A total of 11 adult snow leopards were anesthetized in Xining City, Qinghai Province, China from November 2019 to June 2023. We recorded the onset time, anesthesia duration, head-up time, and walking time.

EMS-induced missense mutation in TaCHLI-7D affects leaf color and yield-related traits in wheat.

Mutations in TaCHLI impact chlorophyll levels and yield-related traits in wheat. Natural variations in TaCHLI-7A/B influence plant productivity, offering potential for molecular breeding. Chlorophyll is essential for plant growth and productivity.

The first outbreak of feline panleukopenia virus infection in captive Pallas's cats in Xining Wildlife Park.

Introduction: In August 2021, an outbreak of Feline Panleukopenia Virus (FPV) was observed in four 3-month-old Pallas' cats at Xining Wildlife Park. Despite timely intervention, the Pallas'cat cubs continued to experience clinical symptoms including diarrhea, seizures, and decreased white blood cell count, and all four cats died.

Methods: FPV clinical suspicions were initially confirmed by positive Polymerase Chain Reaction (PCR) testing.

Photo-Induced Ultrafast Charge Transfer and Air-Stable Radical Formation in Tetraphenylpyrene Derivatives.

Stable organic radicals generated by photo-excitation hold applications in molecular switching devices and information storage. It remains challenging to develop photo-generated radical materials with rapid response and air stability in the solid state. Here, we report a structure based on 1,3,6,8-tetraphenylpyrene derivative (Py-TTAc) displaying photo-induced radicals with air stability in the solid state.

Enantioselective toxicity effect and mechanisms of bifenthrin enantiomers on normal human hepatocytes.

In recent decades, the toxicity of chiral pesticides to non-target organisms has attracted increasing attention. Cellular metabolic disorders are essential sensitive molecular initiating event for toxicological effects. BF is a typical chiral pesticide, and the liver is the main organ for BF accumulation.