Safety and Efficacy Study of Nd: YAG 1064 nm/532 nm Picosecond Laser in the Comprehensive Treatment of Facial Atrophic Acne Scars.

Background: Atrophic acne scars are a common concern among patients with severe acne, often leading to aesthetic and psychological distress. While multiple treatment options exist, effective management remains challenging.

Materials And Methods: This retrospective study analyzed patients with atrophic acne scars treated with the Nd:YAG 1064 nm/532 nm picosecond laser.

Enhanced Adsorption-Photocatalytic Activity of Bismuth-Based Materials via Interfacial Charge Driving Force and Highly Active Crystal Plane.

Large interfacial charge transfer driving force and the incorporation of highly active specific crystalline surfaces have the potential to address the issue of inadequate adsorption-photocatalytic degradation efficiency of photocatalytic materials for organic pollutants. In this study, we synthesized BiWO-BiOCl-BiSiO (BSWC) photocatalysts with excellent adsorption and photocatalytic properties by introducing BiOCl via a double anionic layer in situ induction strategy. The photocatalytic activities of the optimized BSWC-3 were 27.

Construction of inhomogeneous bismuth-based heterojunctions with efficient interfacial charge transport: Bridging of BiOX.

The inefficiency of photogenerated charge transfer between heterojunction interfaces imposes significant limitations on the activity of photocatalytic materials. In this paper, BiWO-BiOSiO-BiSiO-BiOXY (X = Cl, Br, Y=I) (BSBI and BSCI) heterojunctions were successfully constructed by utilizing the structural similarity of Bi-based materials. The effects of different halide species, concentrations and volume ratios on their photocatalytic performance were investigated.

Construction and Performance Study of a Janus Dressing with Sustainable Drainage Function.

In the field of wound exudate management, Janus dressings with unidirectional fluid transport capabilities have garnered extensive attention. However, the hydrophilic layer tends to be saturated during application, which often leads to significant declines in the drainage efficiency. To address this issue, this study constructed a Janus dressing with a hydrophilic-hydrophobic wettability gradient that could continuously evaporate the fluid in the hydrophilic layer.

Fullerene-Buffered Electron Shuttle of Ru/RuO with Switchable Active Sites Enables Robust and Efficient Bifunctional Alkaline Water Electrolysis.

Developing highly-efficient and robust bifunctional electrocatalyst for overall water splitting (OWS) is desirable, but it confronts long-term challenge in the local structural reconstruction of catalyst during the hydrogen and oxygen evolution reaction (HER and OER). As inspired by the stable acid-base buffer system in human life, here we construct an electron buffer system to well address the key issue of structural reconstruction, in which the charge-buffered fullerene renders Ru-based active species to be reversibly shuttled between Ru and RuO during HER and OER. Consequently, the as-prepared Ru-RuO/C catalyst exhibits overpotentials of merely 7 and 194 mV at 10 mA cm for HER and OER in alkaline conditions, respectively.

Prospective, Split-Face Randomized Clinical Trial Comparing Non-ablative Fractional Laser for Periorbital Photoaging in Different Age Groups.

Background: The 1550 nm and 1565 nm non-ablative fractional lasers (NAFL) have recently been introduced as treatments for periorbital photoaging. This prospective, randomized split-face trial aimed to evaluate the safety and effectiveness of these NAFL treatments in addressing periorbital photoaging in Asian patients across various age groups.

Methods: Eighteen patients completed the study, with nine under 45 (Group A) and nine aged 45 or older (Group B).

Steering the Electronic Microenvironment of Ruthenium Sites via Boron Buffering Enables Enhanced Hydrogen Evolution under a Universal pH Range.

Optimizing the microenvironment of active sites is crucial for enhancing the catalytic activity of the hydrogen evolution reaction (HER) across various pH conditions. Here, guided by theoretical predictions of boron (B)-doping's electronic buffering effect on ruthenium (Ru) at the atomic scale, a highly efficient and universal-pH Ru-based HER electrocatalyst (Ru-NBC) by introducing B and nitrogen (N) into a carbon (C) matrix was designed. The Ru-NBC catalyst demonstrated exceptional HER activity, requiring overpotentials of 27, 40, and 68 mV in 1 M KOH, 0.

Elusive modes of Foxp3 activity in versatile regulatory T cells.

Foxp3-expressing CD4 regulatory T (Treg) cells play a crucial role in suppressing autoimmunity, tolerating food antigens and commensal microbiota, and maintaining tissue integrity. These multifaceted functions are guided by environmental cues through interconnected signaling pathways. Traditionally, Treg fate and function were believed to be statically determined by the forkhead box protein Foxp3 that directly binds to DNA.

Light-induced charge transfer from a fullerene to a zeolitic imidazolate framework enhances alkaline electrocatalytic hydrogen production.

In the process of water electrolysis, the oxygen evolution reaction (OER) suffers from a high energy barrier, which has become a key factor restricting the large-scale commercial application of renewable energy technology. Therefore, it is necessary to develop a durable, efficient, low-cost and environmentally friendly OER electrocatalyst. In the present work, a photo-responsive fullerene (C) was encapsulated in the cavity of cobalt-containing flake-like zeolitic imidazolate framework-67 (C@F-ZIF-67).

Energy-Based Skin Rejuvenation: A Review of Mechanisms and Thermal Effects.

Background: Energy-based photoelectric and ultrasonic devices are essential for skin rejuvenation and resurfacing in the field of plastic surgery and dermatology. Both functionality and appearance are impacted by factors that cause skin to age, and various energy types have variable skin penetration depths and modes of transmission.

Aim: The objective is to advise safe and efficient antiaging treatment while precisely and sensitively controlling and assessing the extent of thermal damage to tissues caused by different kinds of energy-based devices.

Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells.

Regulatory T cells (Tregs) establish dominant immune tolerance but obstruct tumor immune surveillance, warranting context-specific mechanistic insights into the functions of tumor-infiltrating Tregs (TIL-Tregs). We show that enhanced posttranslational O-linked N-acetylglucosamine modification (O-GlcNAcylation) of cellular factors is a molecular feature that promotes a tumor-specific gene expression signature and distinguishes TIL-Tregs from their systemic counterparts. We found that altered glucose utilization through the glucose transporter Glut3 is a major facilitator of this process.

Construction and Performance Study of an Injectable Dual-Network Hydrogel Dressing with Inherent Drainage Function.

With the widespread utilization of moist wound dressings, the extended healing time and increased risk of wound infection caused by excessively moist environments have garnered significant attention. The development of hydrogel dressings that can effectively control the wound moisture level and promote healing is very important. Inspired by the pore-opening perspiration effect of the skin, this study constructed an injectable dual-network hydrogel, CMCS-OSA/AG/MXene, by the composition of a dynamic covalent network of carboxymethyl chitosan and oxidized sodium alginate based on the Schiff base and hydrogen bond network of the thermosensitive low-melting-point agar with the advantage of the upper critical solution temperature (UCST) effect.

Phase Engineering-Mediated D-Band Center of Ru Sites Promote the Hydrogen Evolution Reaction Under Universal pH Condition.

The rational design of pH-universal electrocatalyst with high-efficiency, low-cost and large current output suitable for industrial hydrogen evolution reaction (HER) is crucial for hydrogen production via water splitting. Herein, phase engineering of ruthenium (Ru) electrocatalyst comprised of metastable unconventional face-centered cubic (fcc) and conventional hexagonal close-packed (hcp) crystalline phase supported on nitrogen-doped carbon matrix (fcc/hcp-Ru/NC) is successfully synthesized through a facile pyrolysis approach. Fascinatingly, the fcc/hcp-Ru/NC displayed excellent electrocatalytic HER performance under a universal pH range.

Construction and Performance Study of a Dual-Network Hydrogel Dressing Mimicking Skin Pore Drainage for Photothermal Exudate Removal and On-Demand Dissolution.

In recent years, negative pressure wound dressings have garnered widespread attentions. However, it is challenging to drain the accumulated fluid under negative pressures for hydrogel dressings. To address this issue, this study prepared a chemical/physical duel-network PEG-CMCS/AG/MXene hydrogel composed by chemical disulfide crosslinked network of four-arm polyethylene glycol/carboxymethyl chitosan (4-Arm-PEG-SH/CMCS), and the physical network of hydrogen bond of agar (AG).

Dynamic Foxp3-chromatin interaction controls tunable Treg cell function.

Nuclear factor Foxp3 determines regulatory T (Treg) cell fate and function via mechanisms that remain unclear. Here, we investigate the nature of Foxp3-mediated gene regulation in suppressing autoimmunity and antitumor immune response. Contrasting with previous models, we find that Foxp3-chromatin binding is regulated by Treg activation states, tumor microenvironment, and antigen and cytokine stimulations.

Vapor deposition strategy for implanting isolated Fe sites into papermaking nanofibers-derived N-doped carbon aerogels for liquid Electrolyte-/All-Solid-State Zn-Air batteries.

Single-atom catalysts (SACs), with precisely controlled metal atom distribution and adjustable coordination architecture, have gained intensive concerns as efficient oxygen reduction reaction (ORR) electrocatalysts in Zn-air batteries (ZAB). The attainment of a monodispersed state for metallic atoms anchored on the carbonaceous substrate remains the foremost research priority; however, the persistent challenges lie in the relatively weak metal-support interactions and the instability of captured single atom active sites. Furthermore, in order to achieve rapid transport of O and other reactive substances within the carbon matrix, manufacturing SACs based on multi-stage porous carbon substrates is highly anticipated.

Antitumor progenitor exhausted CD8 T cells are sustained by TCR engagement.

The durability of an antitumor immune response is mediated in part by the persistence of progenitor exhausted CD8 T cells (Tpex). Tpex serve as a resource for replenishing effector T cells and preserve their quantity through self-renewal. However, it is unknown how T cell receptor (TCR) engagement affects the self-renewal capacity of Tpex in settings of continued antigen exposure.

Cu/CeO catalysts for reverse water gas shift reactions: the effect of the preparation method.

The reverse water gas shift reaction is one of the most prospective CO utilization approaches. Cu has excellent selectivity for CO and CeO is rich in surface oxygen vacancies for CO activation. These unique properties are often used to develop efficient Cu/CeO catalysts in RWGS.

Identification of wheat seedling varieties based on MssiapNet.

Introduction: In the actual planting of wheat, there are often shortages of seedlings and broken seedlings on long ridges in the field, thus affecting grain yield and indirectly causing economic losses. Variety identification of wheat seedlings using physical methods timeliness and is unsuitable for universal dissemination. Recognition of wheat seedling varieties using deep learning models has high timeliness and accuracy, but fewer researchers exist.

Characterization of the MT-2 Treg-like cell line in the presence and absence of forkhead box P3 (FOXP3).

CD4 forkhead box P3 (FOXP3) regulatory T cells (Tregs) are essential in maintaining immune tolerance and suppressing excessive immune responses. Tregs also contribute to tissue repair processes distinct from their roles in immune suppression. For these reasons, Tregs are candidates for targeted therapies for inflammatory and autoimmune diseases, and in diseases where tissue damage occurs.

Utilization of intense pulsed light for hair removal in pediatric auricular reconstruction using tissue expander: A retrospective cohort study.

This study aimed to investigate the safety and efficacy of depilation with intense pulsed light (IPL) in congenital microtia patients during their reconstruction treatment. The hairy skin was treated with the M22TM system (Lumenis, German) using a filter of 695 to 1200 mm. A contact prob with a window of 15 cm × 35 mm or 8 cm × 15 mm was used at a radiant setting of 14 to 15 J/cm2 in the non-expander group and 13 to 14 J/cm2 in the expander group, both in a single pulse mode.

Sn-mediated topological transformation of Archimedean polyhedra of Prussian blue analogues boosts the electrocatalytic performance for alkaline hydrogen production.

The exploitation of an extraordinary and low-cost electrocatalyst to solve energy shortage and environmental pollution issues is crucial. Herein, a topological Archimedean polyhedron of CoFe PBA (Prussian blue analogue) was synthesized a Sn-induced crystal growth regulation strategy. After phosphating treatment of the as-prepared Sn-CoFe PBA, a Sn-doped binary CoP/FeP hybrid was obtained (Sn-CoP/FeP).

Evaluation of the safety and efficacy of a fractional picosecond 1064 nm laser for post-acne erythema in adult Chinese patients.

Objective: To evaluate the efficacy and safety of fractional 1064 nm picosecond Nd:YAG laser (FPNYL) in the treatment of post-acne erythema (PAE) of adult Chinese.

Materials And Methods: A total of 22 patients received 1 session of treatment and were followed up at the eighth week. Primary outcomes were measured by the Clinician erythema assessment scale (CEAS).

Electroactive injectable hydrogel based on oxidized sodium alginate and carboxymethyl chitosan for wound healing.

Electroactive hydrogel is of great significance in restoring wound currents, promoting cell proliferation, and accelerating the wound healing process. However, the poor dispersity and underlying toxicity of electronic conductive fillers and high concentration of ionic conductors in traditional electroactive hydrogel limited its application in medical care. Herein, an electroactive oxidized sodium alginate/carboxymethyl chitosan/silver nanoparticles (OSA/CMCS/AgNPs) hydrogel was constructed with no additional conductive fillers or synthesized conductive polymers being added, in which the dynamic imine bonds were rapidly formed between aldehyde groups in OSA and amino groups in CMCS, and AgNPs were further in situ formed by UV irradiation.