Low-temperature plasma efficiently promotes blood coagulation with less thermal injury in porcine models.

How to maintain the efficacy of blood coagulation while minimizing thermal damage has been a significant challenge in the optimization of clinical electrosurgical units (ESUs). Recent studies have reported that reactive species produced by low-temperature plasma (LTP) can promote blood coagulation. In this study, two forms of home-made atmospheric pressure plasma jets (APPJs) were compared to argon plasma coagulation (APC) and utilized in three different porcine bleeding models.

Indocyanine green fluorescence-guided imaging enhances the efficiency and accuracy of inferior mesenteric artery lymph node dissection in rectal cancer.

Background: Indocyanine green fluorescence-guided imaging (ICG-FGI) enhances surgical precision in rectal cancer procedures; however, it is technically demanding. This study evaluated the effects of ICG-FGI on the efficacy of lymphadenectomy during radical rectal cancer surgery.

Methods: This multi-center retrospective cohort study analyzed patients who underwent laparoscopic radical resection for rectal cancer between January 2021 and December 2024.

Unraveling the Link Between n-Back Working Memory and Algebraic Ability in Adolescents: Correlations and Training Effects.

Individuals with higher working memory capacities excel in mathematics performance. However, limited research has explored the impact of working memory on adolescents' algebraic ability and the transferability of training effects. Therefore, we conducted the current investigation with Chinese adolescents.

Global, regional, and national burden of idiopathic epilepsy in older adults, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.

Background: Epilepsy among older populations has emerged as a growing global health concern in recent decades. However, comprehensive analyses of epilepsy burden among older adults are limited. This study aimed to assess the global burden of idiopathic epilepsy in the population aged 60 and above from 1990 to 2021 and project trends through 2035.

MOF-derived Co catalysts modified with RuO for durable Li-O batteries.

Li-O batteries have attracted increasing attention due to their high theoretical specific capacity. However, their practical application is limited by factors such as excessively high overpotential and poor rate and cycle performance. It is crucial to find high-efficiency catalysts to improve the kinetics of the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), as well as to provide sufficient space to store undecomposed LiO.

Sex differences in the association of physical activity patterns with all-cause and cardiovascular mortality: a prospective cohort study from NHANES 2007-2018.

Physical activity is widely promoted to reduce mortality risks from all-cause and cardiovascular diseases, yet current guidelines rarely address sex-specific differences or distinguish between occupational (OPA) and non-occupational PA (Non-OPA). This study leverages NHANES 2007-2018 data to evaluate sex differences in mortality benefits from OPA and Non-OPA, with a specific focus on implications for women's health. Participants were categorized into three activity levels: below (< 150 min/week), at (150-300 min/week), and above (> 300 min/week) the recommended guidelines.

Harnessing Radicals for the Selenotrifluoromethylation within a Confined Metal-Organic Framework.

Herein, we report a UiO-67-type metal-organic framework as an efficient photocatalyst for the selenyltrifluoromethylation of terminal alkynes. The CF• radical species can be effectively stabilized within the confined space of UiO-67-Ru, which contributes to the superior -selectivity and catalytic activity. Furthermore, the -selectivity of the obtained ()-α,β-unsaturated selenotrifluoromethyl compounds is well elucidated by means of density functional theory (DFT) calculations and canonical Monte Carlo (CMC) simulation.

The safety, tolerability, pharmacokinetics, and pharmacodynamics of nebulized pegylated interferon α-2b in healthy adults: a randomized phase 1 trial.

Background: Interferons (IFNs) are proteins that combat viruses and regulate the immune system. Studies have demonstrated that aerosol inhalation of IFNα is both effective and safe for treating respiratory infections. However, IFNα has a short half-life and is rapidly cleared by lung defenses.

High-Temperature Rheological and Molecular Dynamics Analysis of Asphalt Modified with SiC Filler.

This study aims to address the increasingly complex environmental demands by enhancing the high-temperature durability of asphalt pavements during service, study on the effect and mechanism of silicon carbide (SiC) ceramic micropowder on the performance of modified asphalt. The rheological properties and modification mechanism of SiC-modified asphalt were analyzed using Saturates, Aromatics, Resins, and Asphaltenes (SARA) fraction analysis, viscosity tests, dynamic shear rheological (DSR) tests, Fourier transform infrared spectroscopy (FTIR), and molecular dynamics (MD) simulations. The results show that SiC ceramic micropowder, with its high specific surface area and rich porous structure, effectively adsorbs the lighter components of asphalt, significantly improving its viscosity and high-temperature stability.

Multifunctional nanozymatic biosensors: Awareness, regulation and pathogenic bacteria detection.

It is estimated that approximately 700,000 fatalities occur annually due to infections attributed to various pathogens, which are capable of dissemination via multiple environmental vectors, including air, water, and soil. Consequently, there is an urgent need to enhance and refine rapid detection technologies for pathogens to prevent and control the spread of associated diseases. This review focuses on applying nanozymes in constructing biosensors, particularly their advancement in detecting pathogenic bacteria.

Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ.

Human periodontal ligament stem cells (hPDLSCs) are candidate seed cells for periodontal tissue regeneration. Enhancing the stemness maintenance and osteogenic differentiation potential of hPDLSCs is conducive to their role in periodontal tissue regeneration. The combination of dasatinib and quercetin, a type of senolytic, has been reported to affect cell senescence.

A hybrid magnetic reset design for the high voltage pulse generator based on forward circuit and magnetic superposition.

Pulsed power technology has found widespread application in environmental governance, biomedicine, food processing, and other fields. This study proposes a pulse generator using forward topology and magnetic superposition to get high-voltage outputs. This design could adjust the pulse width in a relatively larger range by optimizing the coil structure and turns.

Pulse power supply based on Marx-pulse transformer hybrid architecture with MOSFET-resistor-diode magnetic reset control method for dielectric barrier discharge application.

Nanosecond pulse power has many driving advantages in the dielectric barrier discharge (DBD) application field, including better discharge effect, higher discharge efficiency, and lower electrode temperature. A high-voltage pulse voltage power supply (HV-PVPS) with a multi-turn ratio linear pulse transformer (PT) based on Marx circuit and PT topologies are suitable for most DBD plasma applications with fewer expansion modules, lower cost, smaller volume, and higher reliability comparing with the all-solid-state Marx nanosecond pulse power supply. However, during the process of DBD driven by an HV-PVPS based on Marx and PT topologies, the PT is prone to magnetic core saturation, which limits the application for DBD.

Synthesis of an efficient demulsifier derived from cotton cellulose and its demulsification performance in oily wastewater.

Substantial amounts of oily wastewater are inevitably generated during petroleum extraction and petrochemical production, and the effective treatment of these O/W emulsions is crucial for environmental protection and resource recovery. The development of an environmentally friendly, cost-effective, and efficient demulsifier that operates effectively at low concentrations remains a significant challenge. This study introduces an eco-friendly ionic liquid demulsifier, Cotton Cellulose-Dodecylamine (CCDA), which demonstrates exceptional demulsification performance at low concentrations.

A SERS/colorimetric biosensor based on AuNSs@Ag core-shell Prussian blue nanozyme for non-interference and rapid detection of Staphylococcus aureus in milk.

A AuNSs@PB@Ag-Apt surface-enhanced Raman scattering (SERS) probe has been developed by embedding Prussian blue (PB) between Au core and Ag shell. The PB SERS probe illustrates strong SERS activity in the Raman silent region of 2070 cm, and has a zero background signal, ensuring high sensitivity for the detection of Staphylococcus aureus (S. aureus).

Constructing LiF-rich cathode electrolyte interphase to enhance the cyclic stability of lithium-rich manganese-based oxide cathode.

Lithium-rich manganese-based oxide (LRMO) materials hold great potential for high-energy-density lithium-ion batteries (LIBs) but suffer from severe voltage decay and capacity fading. Herein, we report the construction of LiF-rich solid electrolyte interphase on LRMO through a straightforward ball-milling and electrochemical approach, which exhibits remarkable structural stability and enhanced electrochemical performance.

In Situ Synthesis of Iron-Based Porphyrin Metal-Organic Frameworks for the Baeyer-Villiger Oxidation Using Air as an Oxidant.

Iron-based porphyrin metal-organic frameworks (PMOFs) are a new type of material with good stability, catalytic activities, and reusability, which have broad application prospects. However, the synthesis of iron-based PMOFs with different metalloporphyrin units requires a considerable amount of reagents and time. Herein, an in situ synthesis method was developed to simplify the synthetic process of iron-based PMOFs.

Association of dietary intake with pneumothorax: A Mendelian randomization study.

Background: An association between dietary habits and lung disease has been demonstrated in previous studies. Employing Mendelian randomization, we aimed to explore how different dietary intakes relate to pneumothorax, shedding light on the interplay among gut flora, the lung-gut axis, and pneumothorax.

Methods: Employing both two-sample and multi-sample Mendelian randomization (MR) analyses, we investigated 24 dietary intake variables to establish a strong association with pneumothorax.

Achieving 1.7 GPa Considerable Ductility High-Strength Low-Alloy Steel Using Hot-Rolling and Tempering Processes.

To achieve a balanced combination of high strength and high plasticity in high-strength low-alloy (HSLA) steel through a hot-rolling process, post-heat treatment is essential. The effects of post-roll air cooling and oil quenching and subsequent tempering treatment on the microstructure and mechanical properties of HSLA steels were investigated, and the relevant strengthening and toughening mechanisms were analyzed. The microstructure after hot rolling consists of fine martensite and/or bainite with a high density of internal dislocations and lattice defects.

Polyethylene Materials with Tunable Degradability by Incorporating In-Chain Mechanophores.

Polyolefins are recognized as fundamental plastic materials that are manufactured in the largest quantities among all synthetic polymers. The chemical inertness of the saturated hydrocarbon chains is crucial for storing and using polyolefin plastics, but poses significant environmental challenges related to plastic pollution. Here, we report a versatile approach to creating polyethylene materials with tunable degradability by incorporating in-chain mechanophores.

Correlation between short-chain fatty acids and peri-implant disease: A cross-sectional study.

Background: To explore the correlation between short-chain fatty acids (SCFAs) in the peri-implant sulcular fluid (PISF) and peri-implant diseases.

Methods: PISF samples were obtained from implants that have been placed for at least 5 years, and peri-implant clinical parameters were examined. Gas chromatography-mass spectrometry and high-performance liquid chromatography were used to detect SCFAs in PISF.

Mechanochemical Backbone Editing for Controlled Degradation of Vinyl Polymers.

The chemically inert nature of fully saturated hydrocarbon backbones endows vinyl polymers with desirable durability, but it also leads to their significant environmental persistence. Enhancing the sustainability of these materials requires a pivotal yet challenging shift: transforming the inert backbone into one that is degradable. Here, we present a versatile platform for mechanochemically editing the fully saturated backbone of vinyl polymers towards degradable polymer chains by integrating cyclobutene-fused succinimide (CBS) units along backbone through photo-iniferter reversible addition-fragmentation chain-transfer (RAFT) copolymerization.

Epidemiological variations and trends in glaucoma burden in the Belt and Road countries.

Background: Analyzing the glaucoma burden in "Belt and Road" (B&R) countries based on age, gender, and risk factors from 1990 to 2019 in order to provide evidence for future prevention strategies.

Methods: We applied global burden of disease(GBD) 2019 to compare glaucoma prevalence and Years lived with disabilities (YLDs) from 1990 to 2019 in the B&R countries. Trends of disease burden between 1990 and 2019 were evaluated using the average annual percent change and the 95% uncertainty interval (UI) were reported.