Steric hindrance regulation in hydrogen-bonded organic frameworks: from nonporous to microporous.

Steric hindrance regulation is key for adjusting the pore environment of crystalline porous materials, yet few cases show notable structural changes affecting porosity in hydrogen-bonded organic frameworks (HOFs). Herein, we report two HOFs, UPC-HOF-15 and UPC-HOF-16, constructed with methyl- and methoxy-modified isoreticular tricarboxylic acids, respectively. Due to the distinct steric hindrance, UPC-HOF-15 with hydrogen-bonding between carboxyl groups in two peripheral phenyl rings is nonporous, whereas the hydrogen-bonding in microporous UPC-HOF-16 exists between carboxyl groups in the central phenyl ring and one peripheral phenyl ring, both leaving the remaining carboxyl group forming hydrogen-bonding with solvent molecules.

Solvent-etching-induced crystal structure transformation in hydrogen-bonded organic frameworks.

crystal structure transformation is an important method for the emergence of new structures. Currently, there are very limited reports on crystal structure transformation in hydrogen-bonded organic frameworks (HOFs), and such transformation only occurs in response to external stimulation. Herein, we report a rare solvent-etching-induced crystal structure transformation in UPC-HOF-12 and UPC-HOF-13 (UPC-HOF = China University of Petroleum-hydrogen-bonded organic framework).

Investigation and Analysis of Contamination in Food in Yantai City, China: Based on a 14-Year Continuous Monitoring.

is a foodborne zoonotic pathogen that threatens food safety and public health. However, few people have conducted long-term and systematic studies on contamination in food in Yantai City. To investigate the contamination situation of in food and improve the ability of early warning and control of foodborne diseases, a total of 2384 samples from 17 categories were collected from 13 monitoring points in Yantai City, from 2010 to 2023.

Depth weakens effects of long-term fertilization on dissolved organic matter chemodiversity in paddy soils.

Dissolved organic matter (DOM) is pivotal for soil biogeochemical processes, soil fertility, and ecosystem stability. While numerous studies have investigated the impact of fertilization practices on DOM content along soil profiles, variations in DOM chemodiversity and the underlying factors across soil profiles under long-term fertilization regimes remain unclear. Using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) and high-throughput sequencing, this study investigated DOM composition characteristics and microbial community compositions across different soil layers (0-20, 20-40, 40-60, and 60-100 cm) in paddy soil under different long-term fertilization treatments, including Control (no fertilizer), NPK (mineral NPK fertilizer), NPKHS (NPK fertilizer with half straw return), and NPKS (NPK fertilizer with full straw return).

Functionalization of Covalent Organic Frameworks with Cyclopentadienyl Cobalt for CH/CO Separation.

Emerging covalent organic frameworks (COFs) have received great attention for their unique features, but the limited building blocks restrict their structural diversity and performance exploration. Reticular chemistry provides guidance for the structural expansion and performance regulation of COFs. Herein, we constructed two novel two-dimensional (2D) COFs functionalized with cyclopentadienyl cobalt, denoted as UPC-COF-1 and UPC-COF-2, via [4+2] imine condensation with diamine building blocks of different length.

Microplastics from polyvinyl chloride agricultural plastic films do not change nitrogenous gas emission but enhance denitrification potential.

The effects of microplastics (MPs) from agricultural plastic films on soil nitrogen transformation, especially denitrification, are still obscure. Here, using a robotized flow-through system, we incubated vegetable upland soil cores for 66 days with MPs from PE mulching film (F-PE) and PVC greenhouse film (F-PVC) and directly quantified the emissions of nitrogenous gases from denitrification under oxic conditions, as well as the denitrification potential under anoxic conditions. The impact of MPs on soil nitrogen transformation was largely determined by the concentration of the additive phthalate esters (PAEs) containing in the MPs.

Asymmetrical Modification of Cyclopentadienyl Cobalt in Eu-MOF for CH/CO Separation.

The development of novel adsorption materials is of significance for the efficient and low-energy purification of acetylene (CH). Emerging metal-organic framework (MOF) adsorbents demonstrate great application prospects in the field of gas adsorption and separation. Herein, we synthesized a Eu-MOF asymmetrically modified with cyclopentadienyl cobalt exhibiting two different types of cages, denoted as UPC-119.

Subsoil tillage improved the maize stalk lodging resistance under high planting density.

Lodging reduces maize yield and quality. The improvement in maize lodging resistance has proven to be instrumental in maximizing the yield potential of maize varieties under high-density planting. Tillage practices accommodate larger groups by enhancing soil conditions.

Precise Pore Engineering of Zirconium Metal-Organic Cages for One-Step Ethylene Purification from Ternary Mixtures.

One-step purification of ethylene from ternary mixtures (CH, CH, and CH) can greatly reduce the energy consumption of the separation process, but it is extremely challenging. Herein, we use crystal engineering and reticular chemistry to introduce unsaturated bonds (ethynyl and alkyne) into ligands, and successfully design and synthesized two novel Zr-MOCs (ZrT-1-ethenyl and ZrT-1-alkyne). The introduction of carbon-carbon unsaturated bonds provides abundant adsorption sites within the framework while modulating the pore window size.

GABA does not regulate stomatal CO2 signalling in Arabidopsis.

Optimal stomatal regulation is important for plant adaptation to changing environmental conditions and for maintaining crop yield. The guard cell signal γ-aminobutyric acid (GABA) is produced from glutamate by glutamate decarboxylase (GAD) during a reaction that generates CO2 as a by-product. Here, we investigated a putative connection between GABA signalling and the more clearly defined CO2 signalling pathway in guard cells.

Alterations in the gut microbiota of toddlers with cow milk protein allergy treated with a partially hydrolyzed formula containing synbiotics: A nonrandomized controlled interventional study.

Formulas containing intact cow milk protein are appropriate alternatives when human milk (HM) is not feasible. However, for babies with a physician-diagnosed cow milk protein allergy (CMPA), hydrolyzed formulas are needed. We conducted a 3-month, open-label, nonrandomized concurrent controlled trial (ChiCTR2100046909) between June 2021 and October 2022 in Qingdao City, China.

Thiadiazole-Functionalized Th/Zr-UiO-66 for Efficient CH/CO Separation.

Adsorptive separation technology provides an effective approach for separating gases with similar physicochemical properties, such as the purification of acetylene (CH) from carbon dioxide (CO). The high designability and tunability of metal-organic framework (MOF) adsorbents make them ideal design platforms for this challenging separation. Herein, we employ an isoreticular functionalization strategy to fine-tune the pore environment of Zr- and Th-based UiO-66 by the immobilization of the benzothiadiazole group via bottom-up synthesis.

Circulating miR-423-5p levels are associated with carotid atherosclerosis in patients with chronic kidney disease.

Background And Aims: Carotid atherosclerosis is associated with an elevated risk of stroke in patients with chronic kidney disease. However, the molecular basis for the incidence of carotid atherosclerosis in patients with CKD is poorly understood. Here, we investigated whether circulating miR-423-5p is a crucial link between CKD and carotid atherosclerosis.

The GABA shunt contributes to ROS homeostasis in guard cells of Arabidopsis.

γ-Aminobutyric acid (GABA) accumulates rapidly under stress via the GABA shunt pathway, which has been implicated in reducing the accumulation of stress-induced reactive oxygen species (ROS) in plants. γ-Aminobutyric acid has been demonstrated to act as a guard-cell signal in Arabidopsis thaliana, modulating stomatal opening. Knockout of the major GABA synthesis enzyme Glutamate Decarboxylase 2 (GAD2) increases the aperture of gad2 mutants, which results in greater stomatal conductance and reduces water-use efficiency compared with wild-type plants.

Moderate selenium alleviates the pulmonary function impairment induced by cadmium and lead in adults: A population-based study.

Selenium (Se) has been reported to have an antagonistic effect on heavy metals in animals. However, there is no epidemiological study investigating whether Se could protect against the pulmonary toxicity of Cadmium (Cd) and Lead (Pb). Data was collected from the 2011-2012 National Health and Nutrition Examination Survey (NHANES) cycle.

Coffee consumption and abdominal aortic calcification among adults with and without hypertension, diabetes, and cardiovascular diseases.

Background And Aims: This study was performed to investigate the effect of coffee consumption on abdominal aortic calcification (AAC) among adults with and without hypertension, diabetes, and cardiovascular diseases (CVD).

Methods And Results: A total of 2548 participants from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 were included. Coffee consumption was obtained from 24-h dietary recalls.

Decellularized Porcine Conjunctiva in Treating Severe Symblepharon.

This prospective study aimed to evaluate the effectiveness of decellularized porcine conjunctiva (DPC) in the management of severe symblepharon. Sixteen patients with severe symblepharon were enrolled in this study. After symblepharon lysis and Mitomycin C (MMC) application, tarsus defects were covered with residual autologous conjunctiva (AC), autologous oral mucosa (AOM), or DPC throughout the fornix, and DPC was used for all the exposed sclera.

Lung function indices do not affect the incidence of coronary heart disease in patients with sleep-disordered breathing.

Background: Currently, it's unclear whether sleep-disordered breathing (SDB) and reduced lung function could synergistically increase the incidence of coronary heart disease (CHD). Furthermore, the predictive value of different lung function indices for the incidence of CHD remains unknown.

Methods: We enrolled 3749 participants from the Sleep Heart Health Study (SHHS) to conduct a retrospective study.

StomaAI: an efficient and user-friendly tool for measurement of stomatal pores and density using deep computer vision.

Using microscopy to investigate stomatal behaviour is common in plant physiology research. Manual inspection and measurement of stomatal pore features is low throughput, relies upon expert knowledge to record stomatal features accurately, requires significant researcher time and investment, and can represent a significant bottleneck to research pipelines. To alleviate this, we introduce StomaAI (SAI): a reliable, user-friendly and adaptable tool for stomatal pore and density measurements via the application of deep computer vision, which has been initially calibrated and deployed for the model plant Arabidopsis (dicot) and the crop plant barley (monocot grass).

Ideal Cardiovascular Health Metrics Are Associated with Reduced Severity of Hepatic Steatosis and Liver Fibrosis Detected by Transient Elastography.

Life's Simple 7 (LS7) is the American Heart Association's (AHA) proposal for a healthy lifestyle, also known as cardiovascular health (CVH) metrics. However, the association between CVH metrics and the severity of hepatic steatosis and liver fibrosis detected by transient elastography is unknown. We performed a cross-sectional study using the data from the 2017-2018 National Health and Nutrition Examination Survey (NHANES) cycle.

A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease.

Peripheral arterial disease (PAD) has a strong relationship with inflammation. However, it is unclear whether the dietary inflammatory potential is associated with PAD. We aimed to address this knowledge gap.