Genome-based reclassification of Micromonospora veneta Kaewkla et al. 2022 as a later heterotypic synonym of Micromonospora coerulea Jensen 1932 (Approved lists 1980).

In this study, we aimed to clarify the taxonomic positions of Micromonospora veneta DSM 109713 and Micromonospora coerulea JCM 3175 using whole-genome phylogenetic analysis, pangenomic analysis and chemotaxonomic characteristics. The 16S rRNA gene sequences of veneta DSM 109713 and M. coerulea JCM 3175 were highly similar (99.

Farnesoid X Receptor Alleviates Cisplatin-Induced Kidney Inflammatory Injury by Inhibiting Tlr4/NF-κB Pathway.

Inflammatory responses play a critical role in cisplatin-induced acute kidney injury (AKI). Farnesoid X receptor (FXR) has been shown to mitigate kidney dysfunction, but its mechanism remains unclear. This study aims to explore whether FXR reduces cisplatin-induced AKI by modulating inflammation.

Eye Movement Indicator Difference Based on Binocular Color Fusion and Rivalry.

Color fusion and rivalry are two key information integration mechanisms in binocular vision, representing the visual system's processing patterns for consistent and conflicting inputs, respectively. This study hypothesizes that there are quantifiable differences in eye movement indicators under states of binocular color fusion and rivalry, which can be verified through multi-paradigm eye movement experiments. The experiment recruited eighteen subjects with normal vision (nine males and nine females), employing the Gaze Stability paradigm, Straight Curve Eye Hopping paradigm, and Smoothed Eye Movement Tracking paradigm for eye movement tracking.

Heterogeneous effects of socio-economic status on social engagement level among Chinese older adults: evidence from CHARLS 2020.

Introduction: Older adults benefit from social connections as it aids in their adjustment to the physical and psychological changes that come with aging, thereby improving their health, well-being, and overall quality of life.

Methods: This study utilizes data from the 2020 China Health and Retirement Longitudinal Study (CHARLS) to investigate the influence of Socio-economic Status (SES) on the social activity levels of older persons and the disparities observed among demographic groups, employing the Heckman two-stage analysis and heterogeneity analysis.

Results: The results indicate that SES has a significant positive impact on the social engagement of older adults, and this effect varies across different older groups, with women, married individuals living with a spouse, urban residents, those aged 70-79, and individuals with average health conditions.

Developing positive design with innovative thinking framework: A design pedagogical approach to enhance subjective well-being.

Design thinking is the foundation of professional design education, and the shift from zero to professional design skill involves the completion of the transition from single-mindedness to independent and innovative thinking. In this exploratory study on design teaching, we build a novel teaching model by drawing on the connection between students' self-transcendent knowledge and formal knowledge in design thinking. Based on the Design for Happiness framework (DfH), this study uses Positive Emotional Granularity cards (PEG) to stimulate students to identify and categorize various positive emotions.

MiR-21 suppression in macrophages promotes M2-like polarization and attenuates kidney ischemia-reperfusion injury.

MicroRNA-21 (miR-21) is one of the most frequently upregulated miRNAs in response to kidney ischemia-reperfusion (IR) injury, exhibiting both protective and pathogenic effects depending on the cell type, disease state, and target signaling. In this study, we analyzed the function of miR-21 in various cell types to elucidate its role in ischemia-induced inflammation and acute kidney injury (AKI). Utilizing a mouse model of IR injury, we observed significant upregulation of miR-21 in renal tubular epithelial cells and macrophages following IR.

Urine metabolite changes after cardiac surgery predict acute kidney injury.

Background: Acute kidney injury (AKI) is a serious complication in patients undergoing cardiac surgery, with the underlying mechanism remaining elusive and a lack of specific biomarkers for cardiac surgery-associated AKI (CS-AKI).

Methods: We performed an untargeted metabolomics analysis of urine samples procured from a cohort of patients with or without AKI at 6 and 24 h following cardiac surgery. Based on the differential urinary metabolites discovered, we further examined the expressions of the key metabolic enzymes that regulate these metabolites in kidney during AKI using a mouse model of ischemia-reperfusion injury (IRI) and in hypoxia-treated tubular epithelial cells (TECs).

Three-Dimensional SiC/Holey-Graphene/Holey-MnO Architectures for Flexible Energy Storage with Superior Power and Energy Densities.

Although nanostructured materials have recently enabled a dramatic improvement of the current energy-storage units in portable electronics with enhanced functionality, it is still challenging to provide a cost-efficient solution to attain the ultrahigh energy and power densities of supercapacitors (SCs) since nearly arbitrary electrodes are limited to the thinner porous structure with de facto rather low mass loading (∼1 mg cm) because of the huge limitations of pronounced impaired ion transport in subnanometer pores in thicker compact electrodes. In this contribution, we report the fabrication of a macro/mesoporous hybrid hierarchical nanocomposite SiC/holey-graphene/holey-MnO (SiC/HG/h-MnO) with tailored porosity by knitting together the quasi-aligned single-crystalline doped 3C-SiC nanowire array and in situ surface-reduced holey graphene framework into a three-dimensional quasi-ordered structure, which enables the mass growth of ultrathin h-MnO nanosheets at approximately practical levels of mass loading. The produced synergistically favorable interconnected porous architecture allows for the highly efficient electron transfer and rapid ion transport up to interior surfaces of the network.

Reward Modulates Affective Priming Effect in Cognitive Conflict Processing: Electrophysiological Evidence.

Previous research demonstrated that cognitive conflict could induce an affective priming effect, and the stage (detection/resolution) of conflict processing led to different directions (positive/negative) of the affective priming effect. We suggested that rewards play a critical role in the affective priming effect on conflict resolution. The present study used event-related potentials (ERPs), using the arrow flanker task as primes and choosing specific affective words as targets to investigate the affective priming effect induced by cognitive conflict during the resolution stage.

The audio-visual integration effect on music emotion: Behavioral and physiological evidence.

Previous research has indicated that, compared to audio-only presentation, audio-visual congruent presentation can lead to a more intense emotional response. In the present study, we investigated the audio-visual integration effect on emotions elicited by positive or negative music and the role of visual information presentation durations. The participants were presented with audio-only condition, audio-visual congruent condition, and audio-visual incongruent condition and then required to judge the intensity of emotional experience elicited by the music.

Cognitive conflict could facilitate negative stimulus processing: evidence from trait anxiety in the flanker paradigm.

The present study used event-related potentials to investigate the affective priming effect of cognitive conflict and the influence of trait anxiety during the early stage of conflict processing. Participants with relatively high-trait or low-trait anxiety were tested using a combination of flanker task (congruent or incongruent arrows) as primes presented 200 ms before positive or negative words as targets. Behavioral results showed that response times were shorter for negative targets following incongruent primes relative to congruent primes, and vice versa, suggesting that conflicts facilitated the processing of negative targets.

Flexible Nitrogen Doped SiC Nanoarray for Ultrafast Capacitive Energy Storage.

The current trend with integrated energy-storage units in portable electronics lies in continuous advancements in nanostructured materials, thin-film manufacture technologies, and device architectures with enhanced functionality and reliability of existing components. Despite this, it is still challenging to provide cost-efficient solution to further improve the energy and power densities and cyclability of supercapacitors (SCs), especially at ultrafast rates while maintaining their environmentally friendly and even well-run at arbitrary harsh environments character. In this contribution, we report the fabrication of quasi-aligned single crystalline 3C-SiC nanowire (3C-SiCNW) array with tailored shapes and nitrogen-doping (N-doping).

High on/off ratio p-type field-effect transistor enabled by a single heavily Al-doped α-Si3N4 nanowire.

For the first time, we fabricated p-type FETs using an individual heavily Al-doped α-Si3N4 NW with a single-crystal structure. The results show that despite a heavy Al-doping level, a typical device still exhibits high performance with an extremely high on/off ratio, 10(3), at Vds = -5 V.

P-type 3C-SiC nanowires and their optical and electrical transport properties.

We report for the first time the fabrication of p-type SiC nanowire field-effect transistors (FETs) using an individual Al-doped 3C-SiC nanowire with a single crystalline structure. The Raman spectroscopy of the as-grown p-type wire indicates that the linewidth and peak intensity of LO-phonon bands are sensitive to temperature variations.