Publications by authors named "Xinfei Li"

Introduction: Depression ranks as the second leading cause of the global health burden; therefore, identification of its risk and influencing factors is essential to develop more effective multidimensional interventions. The aim of the present study was to analyze the mediating role of family adaptability (FA) on the relationship between insecure attachment (IA) and family functioning (FF) in patients with major depressive disorder (MDD), which currently remains unclear. It also aims to provide a theoretical reference for optimizing rehabilitation interventions.

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Background: The MP1000 system is a newly developed surgical robot in China. This study, based on our single-center experience, evaluates its feasibility, safety, and effectiveness in upper urological repair surgeries.

Methods: This prospective, single-center, single-arm clinical study was conducted from June 2023 to December 2023.

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Objective: Long-term physiological, psychological, economic, and lifestyle pressures make maintenance hemodialysis (MHD) patients prone to anxiety and depression. This study aims to evaluate the effects of mindfulness meditation combined with progressive muscle relaxation on sleep and emotional disorders in hemodialysis patients with sarcopenia.

Methods: Patients with uremic sarcopenia and sleep issues were randomly divided into a control group (n=24) and an intervention group (n=25), with an average age of 45.

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Ion and protein adsorption occurs on the implant surface upon contact with tissues. Increasing research efforts focus on modifying or constructing the physical and chemical properties of surfaces to enhance antifouling capabilities. However, conventional evaluation methods, such as artificial urine and protein immersion models, often fail to replicate the complex interfacial interactions occurring .

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Purpose: Sexual minority stigma contributes to mental health disparities among men who have sex with men (MSM) in China. This study examined how stigma, social avoidance, and social support influence depression in MSM in order to identify intervention targets.

Methods: A purposive sampling strategy recruited 586 MSM (M[age] = 29.

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Objectives: Percutaneous nephropexy (PCN) has been demonstrated as a feasible method for treating nephroptosis. This study describes an improved technique for PCN that better addresses the issue of nephroptosis.

Materials And Methods: We reviewed 4 patients who underwent the improved PCN procedure between January 2021 and January 2023.

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Dehydrins (DHNs) belong to the second family of late embryogenesis abundant (LEA) proteins, which are widely distributed in plants. We cloned a SK-type DHN gene named in Zheng yin 1 cultivar of . An ERF-type transcription factor TaERF4a was found to be involved in the regulation of the dehydrin gene in our last report.

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We report a surgical technique combining an appendiceal interposition with a Boari flap for the long right ureteral strictures. The major surgical procedures include dissection of the ureter, resection of the stricture lesion and the fibrous scar, performing a psoas hitch and assessment, preparing tubular appendix, and anastomosing the ureteral stump to the apex of the appendix, formation of the bladder flap, and anastomosing the base of the appendix to the bladder flap. At the last follow-up, the patient has recovered well with no complication.

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Objective: To evaluate the feasibility and usefulness of cine magnetic resonance urography (MRU) as a novel examination for primary obstructive megaureter (POM).

Material And Methods: The study was conducted on 44 patients with POM who underwent cine MRU from May 2020 to October 2022. Referring to the international system of vesicoureteral reflux, patients were divided into the low-risk (grade I-IV) and the high-risk (grade V) groups.

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Purpose: Accurate differentiation of benign renal lesions from renal cell carcinoma (RCC) is crucial for optimized management, particularly for small renal lesions (≤4 cm in diameter). This study aimed to integrate clinical data, radiomic features, and deep features to improve diagnostic performance in distinguishing benign renal lesions from RCC.

Methods: In this retrospective study, radiomic and deep scores were constructed using the AutoGluon-Tabular classifier based on radiomic and deep features extracted from the whole region of CT imaging.

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Objective: To develop a three-dimensional (3D) image based extended tumor plane technique for robotic-assisted partial nephrectomy (RAPN).

Methods: We prospectively enrolled patients with a local renal tumor for RAPN between March 2019 and Mar 2022. 3D virtual model was reconstructed based on the computed tomography urography.

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Traumatic ureteral injury is a rare and challenging condition of the urinary system. To summarize the clinical features of patients with traumatic ureteral injury and examine the literature on traumatic ureteral injuries from the past 20 years. The clinical data of 30 patients with traumatic ureteral injury in Peking University First Hospital, Beijing Jiangong Hospital, as well as Emergency General Hospital from August 2015 to August 2023 were retrospectively collected.

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Background: The aim of this study was to report our technical experience and mid-term outcomes of robot-assisted redo ureteral reimplantation in adults following failed primary ureteral reimplantation.

Methods: Twelve patients underwent robot-assisted redo ureteral reimplantation from December 2020 to May 2022 at double centers. Surgical procedures included anti-reflux dismembered submucosal tunnel reimplantation, anti-reflux dismembered nipple reimplantation, and anti-reflux non-dismembered submucosal tunnel reimplantation.

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Background: The aim of this study was to report our technique and medium-term outcomes of modified robot-assisted laparoscopic dismembered pyeloplasty (RALDP) in the Lithotomy Trendelenburg position for treating adult ureteropelvic junction obstruction (UPJO) with horseshoe kidney (HSK).

Methods: Between March 2021 and March 2023, 11 adult patients with UPJO and HSK underwent modified RALDP in the lithotomy Trendelenburg position. Patient demographic characteristics, perioperative parameters, and follow-up outcomes were collected prospectively and analyzed.

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Article Synopsis
  • Ectopic renal hydronephrosis is a rare condition with limited literature mainly consisting of case studies, presenting challenges for surgical management due to anatomical variations.
  • This study examined six adult patients who underwent minimally invasive pyeloplasty, with a median age of 27, showcasing different types of ectopic kidneys and varying surgical techniques.
  • After follow-up, 66.7% achieved surgical success, although some patients faced complications, highlighting the need for tailored approaches and continuous research in surgical techniques for this condition.
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Purpose: To examine the role and mechanism of thrombospondin-1 (TSP1) in the development of fibrosis in diabetes mellitus-induced erectile dysfunction (DMED).

Materials And Methods: DMED was induced by intraperitoneal streptozotocin injection. All rats were categorized into three groups: control group (n=8), DMED group (n=8) and DMED+Leu-Ser-Lys-Leu (LSKL) group (n=8).

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Purpose: To develop a novel adaptation of the Whitaker test for assessing the surgical effects of ileal ureter replacement (IUR), and to evaluate its feasibility and effect in the postoperative evaluation.

Patients And Methods: From November 2021 to September 2023, patients undergoing the modified Whitaker test following IUR were prospectively enrolled. The relative pressure was defined as the pelvis pressure minus the bladder pressure.

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Article Synopsis
  • The study assesses the long-term outcomes of endoscopic management techniques for primary obstructive megaureter (POM) in adults, involving 76 patients treated from September 2015 to January 2024.
  • Using endoscopic dilation and additional incision methods, the procedures showed a high success rate of 92.1% over an average follow-up of 42 months, with no intraoperative complications.
  • The findings suggest that this endoscopic approach is a safe and effective first-line treatment for adult POM, potentially improving patient outcomes significantly.
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Article Synopsis
  • * The study details a successful surgery on a 59-year-old woman, utilizing the KangDuo Surgical Robot 2000 Plus, involving harvested ileal segments for ureteral replacement, without any complications.
  • * The operation showcased efficient metrics, including a 271-minute operation time and minimal blood loss, but suggests the need for further research with more patients for comprehensively assessing long-term safety and effectiveness.
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Objective: To investigate the feasibility, safety and effectiveness of robot-assisted laparoscopic buccal mucosa graft ureteroplasty in the treatment of complex long proximal ureteral stricture.

Methods: The clinical data of 20 patients with proximal ureteral stricture undergoing robot-assisted laparoscopic buccal mucosa graft ureteroplasty admitted to the Department of Urology, Peking University First Hospital and Beijing Jiangong Hospital from July 2022 to January 2023 were prospectively collected and analyzed. Intraoperative conditions, postoperative complications and follow-up data were also recorded and analyzed.

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Article Synopsis
  • This study analyzes the outcomes of ileal ureter with ileocystoplasty (IUC) in 20 patients, comparing minimally invasive procedures (like laparoscopic and robotic surgeries) to open surgeries over a period from December 2017 to April 2023.
  • Results show that while both methods were effective, minimally invasive surgeries resulted in less blood loss and shorter hospital stays than open surgeries.
  • The success rate for IUC was 100%, but the study suggests that larger trials with longer follow-up are necessary for more definitive conclusions.
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Background: To evaluate the feasibility and safety of dual-console telesurgery with the new KangDuo system in an animal experiment and clinical study.

Methods: Six canine models were performed radical prostatectomy with dual-console KanDuo surgical robot-1500 (KD-SR-1500-RARP). The perioperative outcomes, physical and mental workload of the surgeon were collected.

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