[Effect of different phosphorus application on morphological traits, active ingredients and rhizosphere soil microbial community of Polygala tenuifolia].

To investigate the effects of phosphorus fertilizer on the morphological traits, active ingredients and rhizosphere soil microbial community of Polygala tenuifolia. The phosphorus fertilizer was calculated in terms of P_2O_5. Five treatments were set up: 0(CK), 17(P1), 34(P2), 51(P3), and 68(P4) kg per Mu(1 Mu≈667 m~2).

Factors associated with secondary thoracotomy for hemostasis following lung surgery: a retrospective analysis.

Purpose: This study aimed to systematically investigate the causes and management of secondary thoracotomy for hemostasis following lung cancer surgery. Although infrequent, secondary thoracotomy can lead to prolonged hospitalization, increased costs, and additional patient trauma. However, prior research has been limited to case reports or experience-based summaries, lacking a comprehensive analysis of this issue.

Novel Nanoadjuvant for Subunit Vaccines: Cyclic Seven-Membered Tertiary Amine-Based Polymer-Grafted Ethoxy-Acetalated Dextran Nanoparticles Encapsulating CpG Oligodeoxynucleotides.

CpG oligodeoxynucleotides (ODNs) are synthetic Toll-like receptor 9 (TLR9) agonists that promote Th1-biased immune responses. However, their clinical utility is limited by rapid nuclease degradation and poor cellular uptake in antigen-presenting cells (APCs). To overcome this, we developed a pH-responsive nanoadjuvant, Ace-Dex-PC7A@CpG, composed of a cyclic seven-membered tertiary amine-based polymer (PC7A) grafted onto ethoxy-acetalated dextran (Ace-Dex) encapsulating CpG ODN 1668.

Electron-rich and electron-poor active centers induced by interface coupling to enhance the degradation of fluorinated antibiotic via peroxymonosulfate activation.

The water pollution issue triggered by antibiotic was a great challenge facing humanity, and it was necessary to develop an effective remediation technique. In this work, FeO/CoO composite with internal electric field was fabricated by a simple method. The presence of internal electric field reduced the interfacial resistance and facilitated the charge transfer, so stimulating the electron transport during reaction process.

Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation.

Rice (Oryza sativa) is one of the most important staple food crops worldwide, and its wild relatives serve as an important gene pool in its breeding. Compared with cultivated rice species, African wild rice (Oryza longistaminata) has several advantageous traits, such as resistance to increased biomass production, clonal propagation via rhizomes, and biotic stresses. However, previous O.

Towards a closed loop retinal prosthesis: measuring electrically evoked retinal responses using large electrodes.

Sensory prostheses use arrays of electrodes to stimulate neural tissue and restore a sense of vision or hearing. At perceptible levels of stimulation, the current from each electrode spreads and causes overlapping regions of neural activation. This lack of specificity results in perceptual deficits.

Quality characteristics and volatile organic compound profiling of yellow mushrooms at different cap opening stages.

Yellow mushrooms (Floccularia luteovirens), which grow in high-altitude regions, are a component of traditional Tibetan medicine and have high nutritional value. In this study, the basic quality indices and volatile organic compounds (VOCs) of yellow mushrooms with different cap opening stages were determined. The volatile compounds (VOCs) were determined by headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS) technology.

Multi-spectral imaging techniques for temperature measurement in explosion fields.

Aiming at the extensive temperature range of the explosion temperature field and the challenging testing environment, this paper presents a high-precision, wide-range multi-spectral radiometric temperature measurement method based on multi-spectral imaging. This method aims to accurately measure the high temperatures associated with the explosion field of 40 kg of aluminum-containing explosives. We uniformly coated a 25-band multi-spectral filter array (MFA) onto a CMOS sensor to construct a multi-spectral radiation camera (MRC).

Integrated biotechnological and AI innovations for crop improvement.

Crops provide food, clothing and other important products for the global population. To meet the demands of a growing population, substantial improvements are required in crop yield, quality and production sustainability. However, these goals are constrained by various environmental factors and limited genetic resources.

A rapid LASV detection method based on CRISPR-Cas13a and recombinase aided amplification with special lateral-flow test strips.

Lassa virus (LASV) is a high-risk pathogen associated with severe viral hemorrhagic fever in both humans and animals. Owing to its significant treatment challenges and high infectivity, LASV is classified as a biosafety level 4 (BSL-4) pathogen. It is essential to establish a rapid LASV detection method to prevent and control the disease.

Case Report: Do not diagnose lung cancer as pneumonia: continue to monitor a case of invasive mucinous adenocarcinoma as it progresses from small to large.

Background: Invasive mucinous adenocarcinoma (IMA) is a rare malignant tumor of the lung, characterized as a distinct subtype of lung adenocarcinoma, with unique histological features and clinical behavior. Because the diagnosis is often delayed due to its imaging characteristics resembling pneumonia, this neoplasm is associated with a poor prognosis.

Case Presentation: This case report describes a 69 years-old man who underwent an asymptomatic health examination, during which small ground-glass opacities were found in the periphery of both lungs.

Research on Time Constant Test of Thermocouples Based on QNN-PID Controller.

The aim of this study is to solve the problem of it being difficult to obtain quantitative step signals when testing the time constant of thermocouples using the laser excitation method, thereby restricting the accuracy and repeatability of the test of the time constant of thermocouples. This paper designs a thermocouple time constant testing system in which laser power can be adjusted in real time. The thermocouple to be tested and a colorimetric thermometer with a faster response speed are placed on a pair of conjugate focal points of an elliptic mirror.

Design of a Superhydrophobic Photothermal Shape-Memory Material Based on Carbon-Nanotubes-Doped Resin for Anti-Icing/De-Icing Applications.

Icing on power lines and wings can cause serious economic damage and safety hazards. While superhydrophobic materials show promise for anti-icing applications, their passive anti-icing mechanisms require external energy activation, highlighting the need for the development of active de-icing materials with energy-to-heat conversion capabilities. Here, we developed three photothermal superhydrophobic shape-memory polymers with anti-icing performance (PSSPs), with 3%, 5%, and 7% CNT doping ratios, through a two-step process: resin preparation and laser-processing modification.

Small Extracellular Vesicles Orchestrate Cisplatin-Induced Ototoxicity: Potential Biomarker and Targets Discovery.

Cisplatin-induced ototoxicity remains a clinical dilemma with limited mechanistic understanding and no food and drug administration (FDA)-approved therapies. Despite emerging roles of small extracellular vesicles (sEV) in drug ototoxicity, their molecular cargo profiles and causal roles to cisplatin-induced ototoxicity are unexplored. This study systematically investigates sEV derived from cochlear explants treated with cisplatin (Cis-sEV) and controls (Ctrl-sEV) using multi-omics profiling.

In vitro VS in vivo transcriptional approach provides new insight on temporal cold response which works without root system in tea plant (Camellia sinensis (L.) Kuntze).

Low temperature stress is the main constraint for the stable yield and production of many crops. The differences of the short- and long-term- cold responses remains unclear. In this study, in vitro VS in vivo transcriptome analysis was used to reveal the shared and specific responsive pathways under cold stress.

ZIF-8-induced fluorescence-enhanced multifunctional MOF-on-MOF hydrogels for efficient adsorption and sensitive detection of uranyl ions in water.

Accidental leakage of uranium causes a huge threat to human health and environmental security. Herein, a novel fluorescent MOF-on-MOF hydrogel complex, namely Tb-MOF@ZIF-8@PAM, is constructed using a "three-in-one" synthetic strategy for the simultaneous adsorption enrichment and sensitive detection of uranyl ions (UO) in water. Combining ZIF-8 with Tb-MOF enables the composite to exhibit remarkable fluorescence enhancement, large fluorescence quantum yield, and exceptional stability.

High-accuracy multi-spectral thermometry via 25-band multi-spectral filter array imaging.

We present a radiant temperature measurement technique utilizing a 25-band filter array imaging system, which effectively improves the temperature measurement range and temperature measurement accuracy. The CMOS sensor of the multi-spectral camera is uniformly photolithographed with a 25-band filter array, allowing for the simultaneous acquisition of spectral information and radiation intensity from the temperature source in a single image. A calibration experiment was conducted using a standard blackbody source to determine the relationship between the instrumental response values and the theoretical radiation intensity across each wave band of the multi-spectral camera.

Chromosome-level genomes of Arctic and Antarctic mosses: Aulacomnium turgidum and Polytrichastrum alpinum.

Bryophytes play a crucial role in the ecosystems of polar regions. These simple plants are among the predominant vegetation types in both Arctic and Antarctic landscapes, where they contribute significantly to biodiversity and ecological stability. Here, we report the chromosome-level genomes of two polar moss species, the Arctic Aulacomnium turgidum and Antarctic Polytrichastrum alpinum.

The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis.

Background: The Hong Kong orchid tree Bauhinia × blakeana Dunn has long been proposed to be a sterile interspecific hybrid exhibiting flower heterosis when compared to its likely parental species, Bauhinia purpurea L. and Bauhinia variegata L. Here, we report comparative genomic and transcriptomic analyses of the 3 Bauhinia species.

A novel stroke classification model based on EEG feature fusion.

Stroke is the leading cause of disability and death worldwide. It severely affects patients' quality of life and imposes a huge burden on the society in general. The diagnosis of stroke relies predominantly on the use of neuroimaging.

Targeting Programmed Cell Death in Acquired Sensorineural Hearing Loss: Ferroptosis, Necroptosis, and Pyroptosis.

Sensorineural hearing loss (SNHL), the most commonly-occurring form of hearing loss, is caused mainly by injury to or the loss of hair cells and spiral ganglion neurons in the cochlea. Numerous environmental and physiological factors have been shown to cause acquired SNHL, such as ototoxic drugs, noise exposure, aging, infections, and diseases. Several programmed cell death (PCD) pathways have been reported to be involved in SNHL, especially some novel PCD pathways that have only recently been reported, such as ferroptosis, necroptosis, and pyroptosis.

Operando Optical Microscopy for Visualization of Dendrite Growth in an Argyrodite LPSCl-Polymer Composite Electrolyte.

Herein, we demonstrate the utility of optical microscopy as an accessible technique for the in situ visualization of dendrite growth within polymer-sulfide composite solid-state electrolytes. The composite electrolyte features in situ polymerization and cross-linking of the polymer between ceramic particles, which opens up extensive opportunities for accelerated materials discovery, given the vast array of acrylate/methacrylate monomers available. Specifically, the cross-linked polymer poly(triethylene glycol dimethacrylate) (poly(TEGDMA)) was observed to effectively fill pores and inhibit dendrite growth at the lithium metal interface, attributed to its glassy state at room temperature.

Genetic associations of plasma proteins and breast cancer identify potential therapeutic drug candidates.

To address the pressing need to improve breast cancer outcomes, we identify 9 plasma proteins with significant associations to breast cancer, namely ULK3, CSK, ASIP, TLR1 in breast cancer, ADH5, SARS2, ULK3, UBE2N in Luminal A subtype, PEX14 in Luminal B subtype. Tumor immune cell infiltration analysis and mutation phenotypes in mice further demonstrate a complex pattern of interaction between these genes and immune responses. Compared to normal tissues, tumor tissues exhibit reduced expression of ULK3 and CSK.

An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation.

With rapid advancements in single-cell RNA sequencing (scRNA-seq) technologies, exploration of the systemic coordination of critical physiological processes has entered a new era. Here, we generated a comprehensive Arabidopsis single-nucleus transcriptomic atlas using over 1 million nuclei from 20 tissues encompassing multiple developmental stages. Our analyses identified cell types that have not been characterized in previous single-protoplast studies and revealed cell-type conservation and specificity across different organs.