Assessing the Potential Distribution of the Traditional Chinese Medicinal Plant in China Under Climate Change: A Biomod2 Ensemble Model-Based Study.

, a valuable Chinese medicinal plant, faces habitat shifts under climate change. In order to better utilize the medicinal properties of and conduct further investigations, this study utilized the Biomod2 ensemble model to predict and analyze the potential expansion and contraction of suitable habitat areas for in China under changing climatic and environmental conditions. The results showed that, compared to the pre-screened models, the ensemble model significantly improved the prediction accuracy.

Whole-genome resequencing unveils the phylogeographic coevolution of Oncomelania hupensis with Yangtze River dynamics in China.

The freshwater snail Oncomelania hupensis is the only intermediate host of Schistosoma japonicum and is currently mainly distributed in the middle and lower reaches of the Yangtze River in China. To explore the evolutionary history and adaptations of O. hupensis, we re-sequenced 283O.

Mechanism of San Jie Tong Mai Fang in Atherosclerosis Attenuation by JAK/STAT-mediated Inhibition of Macrophage M1 Polarization.

Macrophage polarization influences the atherosclerotic plaque microenvironment by driving inflammatory responses, with the JAK/STAT signaling pathway serving as a critical regulator of this process. This study investigated whether San Jie Tong Mai Fang (SJTMF), an herbal formulation reported to promote M2-type macrophage polarization, alleviates atherosclerosis (AS) by modulating the JAK/STAT signaling pathway. An AS model was established in ApoE mice via 12-week high-fat diet feeding, followed by 4-week treatment with SJTMF alone or combined with a JAK inhibitor or macrophage scavenger.

Village and age based precision mapping of schistosomiasis and soil-transmitted helminths in Chevakadzi ward of Shamva district in Zimbabwe.

Schistosomiasis is earmarked for elimination as a public health problem, while morbidity control is a priority for soil-transmitted helminthiasis (STH) by 2030. To develop targeted interventions for the two diseases, micro-mapping and an understanding of disease transmission dynamics across different age groups are necessary. This study determined the age-stratified and ward-level prevalence of schistosomiasis and STH in Chevakadzi ward, Shamva district, Mashonaland Central province, Zimbabwe.

Licochalcone D mitigates intracerebral hemorrhage-induced ferroptosis of neurons through COX2 inhibition.

Objective: This study aims to assess LCD's neuroprotective pharmacological effects against SBI post-ICH and identify its ferroptosis-inhibiting targets.

Methods: Animal models of ICH and cellular models of SBI were established. Subsequently, gradient concentrations of LCD were administered at both the animal and cellular/molecular levels.

Zoonotic diseases in China: epidemiological trends, incidence forecasting, and comparative analysis between real-world surveillance data and Global Burden of Disease 2021 estimates.

Background: Zoonotic diseases remain a significant public health challenge in China. This study examines the temporal trends, disease burden, and demographic patterns of major zoonoses from 2010 to 2023.

Methods: This study analyzed data from China's National Notifiable Infectious Disease Reporting System (NNIDRS, 2010-2023) on nine major zoonoses, including echinococcosis, brucellosis, leptospirosis, anthrax, leishmaniasis, encephalitis (Japanese encephalitis), hemorrhagic fever, rabies, and schistosomiasis.

Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol.

Background: Schistosomiasis is one of the major neglected tropical diseases in Africa, accounting for approximately 90% of the global burden. In Zimbabwe, Schistosoma haematobium and S. mansoni infections are endemic.

Positive effects of forest fragmentation on bryophyte diversity in subtropical fragmented forests: evidence from land-bridge islands.

Introduction: Habitat fragmentation () represents a landscape-scale process involving both habitat loss and the breaking apart of habitat (habitat fragmentation ). In ecological studies, understanding the impacts of habitat fragmentation on biodiversity remains a critical challenge. While previous research has explored the effects of fragmentation on various ecosystems, significant gaps remain in our understanding of its impacts on bryophyte assemblages.

Corrigendum to "Identification of habitat suitability for the dominant zoonotic tick species on Chongming Island, China"[Science in One Health 3 (2024) 100068].

[This corrects the article DOI: 10.1016/j.soh.

Global, regional, and national burden of neglected tropical diseases and malaria in the general population, 1990-2021: Systematic analysis of the global burden of disease study 2021.

Background: Neglected Tropical Diseases (NTDs) and malaria present considerable health obstacles, particularly impacting the socio-economic progress in at-risk areas. We aimed to estimate the burden, trends, and inequalities of NTDs and malaria globally, regionally, and nationally from 1990 to 2021.

Methods: The study utilized data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, encompassing 204 countries and territories, spanning 21 global regions, including diverse populations across different Socio-Demographic Index (SDI) levels.

Snail control as a crucial approach to schistosomiasis elimination: evidence from the People's Republic of China.

Background: Asian schistosomiasis is projected to be eliminated by 2030 according to World Health Organization road map for neglected tropical diseases 2021-2030. Snail control is an important measure but has not yet been systematically evaluated at a country scale. Here, we report the findings from a nationwide survey to demonstrate the dynamics of Oncomelania and its potential role in transmission interruption of schistisomiasis in the People's Republic of China (P.

Matrix metalloproteinase 7 (MMP7) as a molecular target for Mycoplasma gallisepticum (MG) resistance in chickens.

Mycoplasma gallisepticum (MG) causes chronic respiratory disease (CRD), posing a significant threat to global poultry production. Current preventive strategies face limitations, emphasizing the need for alternative approaches such as breeding for disease resistance. This study identifies the matrix metalloproteinase 7 (MMP7) gene as a key factor in CRD resistance.

African Schistosomiasis: A Framework of Indicators Assessing the Transmission Risk and Intervention Effectiveness.

Schistosomiasis, a parasitic disease with a complex transmission mechanism, requiring a snail intermediate host, is influenced by biology, the environment, human behavior and the prevailing socioeconomic situation. This study aimed to systematically investigate the importance and feasibility of indicators related to the factors influencing transmission and intervention measures for and . Based on a literature review and group discussions according to the Delphi method, a framework questionnaire was designed.

Global, regional, and national burden of HIV-negative tuberculosis, 1990-2021: findings from the Global Burden of Disease Study 2021.

Background: Tuberculosis (TB) is a major infectious disease with significant public health implications. Its widespread transmission, prolonged treatment duration, notable side effects, and high mortality rate pose severe challenges. This study examines the epidemiological characteristics of TB globally and across major regions, providing a scientific basis for enhancing TB prevention and control measures worldwide.

Integrated Eco-Health approach significantly reduces helminth infections in endemic Khong islands with emphasis on Schistosoma mekongi.

Background: Helminth infections, including Opisthorchis viverrini, hookworm, and Trichuris trichiura, are prevalent in Khong district, Champasack province, southern Lao People's Democratic Republic (PDR). Schistosomiasis caused by Schistosoma mekongi is of public health concern on the islands of the Khong district. This study aimed to assess the impact of an Eco-Health/One-Health approach in combination with mass drug administration (MDA) to reduce these helminth infections.

China's One Health governance system: the framework and its application.

One Health is an interdisciplinary approach that promotes the resolution of complex health issues through collaboration across multiple disciplines. In addition to accountability, the One Health governance structure fosters shared understanding, trust, and an appreciation for diverse perspectives and requirements. This article provides a comprehensive analysis of the current integration of the One Health approach within China's existing health governance framework.

Alarming and calming: Dual functions of S100A9 on Mycoplasma gallisepticun infection in avian cells.

Mycoplasma gallisepticum (MG) is the primary causative agent of chronic respiratory disease (CRD) in chickens, characterized by respiratory inflammation. S100A9 plays a pivotal role in modulating the inflammatory response to microbial pathogens. Our prior investigation revealed a significant upregulation of S100A9 in the lungs of chickens following MG infection.

Schistosomiasis transmission in Zimbabwe: Modelling based on machine learning.

Zimbabwe, located in Southern Africa, faces a significant public health challenge due to schistosomiasis. We investigated this issue with emphasis on risk prediction of schistosomiasis for the entire population. To this end, we reviewed available data on schistosomiasis in Zimbabwe from a literature search covering the 1980-2022 period considering the potential impact of 26 environmental and socioeconomic variables obtained from public sources.

Mapping macrostructural and microstructural brain alterations in patients with neuronal intranuclear inclusion disease.

Background And Purpose: Neuronal intranuclear inclusion disease (NIID) is a rare complex neurodegenerative disorder presents with various radiological features. The study aimed to investigate the structural abnormalities in NIID using multi-shell diffusion MR.

Materials And Methods: Twenty-eight patients with adult-onset NIID and 32 healthy controls were included.