Objective: To compare the microleakage of three different restorative materials used in pre-endodontic buildup: Bulk Filled Composite, Light Cured Glass Ionomer Cement (GIC), and Conventional GIC.
Methods: This in-vitro study involved 36 extracted human molars divided into three groups, each restored with one of the aforementioned materials. Standardized class V cavities were prepared and restored according to manufacturer instructions.
Background: Endodontically treated teeth are susceptible to fractures due to loss of structural integrity. Reinforcing these teeth with appropriate restorative materials is crucial for restoring their function and longevity. The study was undertaken to compare the fracture resistance of endodontically treated teeth restored with different restorative materials.
View Article and Find Full Text PDFBackground: Root canal therapy relies heavily on the effectiveness of the sealer used to ensure successful treatment outcomes. Bioceramic and resin-based sealers are commonly employed, each offering distinct advantages and drawbacks. This study aimed to compare the effectiveness of bioceramic versus resin-based sealers in root canal therapy, focusing on microbial leakage, seal integrity, postoperative pain, and healing rates.
View Article and Find Full Text PDFBackground: Endodontic treatment comprises of thorough cleaning and shaping of the canal through appropriate instrumentation and irrigation. The key component of an efficient endodontic therapy is irrigation because it performs numerous crucial chemical, mechanical, and microbiological tasks. Efficient irrigation plays a crucial role in bacterial reduction.
View Article and Find Full Text PDFIntroduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health concern. MASLD is strongly linked to obesity, sedentary lifestyles, and metabolic syndrome. In India, the prevalence of MASLD exhibits regional variations because of genetic, dietary, and socioeconomic factors.
View Article and Find Full Text PDFEndophytic fungi represent a significant renewable resource for the discovery of pharmaceutically important compounds, offering substantial potential for new drug development. Their ability to address the growing issue of drug resistance has drawn attention from researchers seeking novel, nature-derived lead molecules that can be produced on a large scale to meet global demand. Recent advancements in genomics, metabolomics, bioinformatics, and improved cultivation techniques have significantly aided the identification and characterization of fungal endophytes and their metabolites.
View Article and Find Full Text PDFThe Ganga river, one of the largest and most culturally significant rivers in India, supports millions of people living along its banks. However, extensive use and untreated wastewater discharge have led to significant contamination. This study utilizes land use and land cover (LULC) analysis, along with regular water sampling from 2021 to 2222, to assess variations in physical, chemical, and biological characteristics and evaluate health risks posed by heavy metals across eight monitoring sites in the Ganga and Yamuna rivers, Prayagraj, India.
View Article and Find Full Text PDFMWCNT is being explored in various sectors like medical healthcare, electronics, aerospace, defence research, and many more leading to the continuous generation of waste discharged into water sources. Once introduced into the environment it may adversely affect flora and fauna. It is high time MWCNT should be recovered, treated, and degraded from wastewater.
View Article and Find Full Text PDFIntroduction: Fungal endophytes have mutualistic associations with the plant's host, communicating through genetic and metabolic processes. As a result, they gain the ability to generate therapeutically effective metabolites and their derivatives.
Methods: The current study aims to assess antioxidant potential along with the identification of robust metabolites within the crude extract of a potent endophytic fungus isolated from leaf tissues of the Linn.
Eur J Clin Microbiol Infect Dis
March 2025
Dengue virus is an arbovirus transmitted through the bite of infected Aedes mosquitoes. Many unusual clinical features are being reported in dengue. Dengue complicated with hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal condition.
View Article and Find Full Text PDFIntroduction: Mucoid degeneration of the cruciate ligament is a well-known entity, but symptomatic lesions are rare. It is even rarer to find symptomatic posterior cruciate ligament mucoid degeneration than the anterior cruciate ligament.
Case Report: A 63-year-old male presented to our hospital complaining of posterior knee pain was induced when the knee approached full flexion without episodes of trauma, despite conservative treatment over the preceding 8 months, his symptoms persisted.
Introduction: Osteonecrosis of femoral head (ONFH) is a disabling condition of the hip joint with multifactorial etiology and is associated with genetic predilection and exposure to certain risk factors most commonly being chronic alcohol or steroid intake. Total hip arthroplasty (THA) remains the gold standard for end-stage femoral head osteonecrosis. The outcome after the surgery is mainly affected by age, activity levels and other factors that affect the development of ONFH.
View Article and Find Full Text PDFOvarian cancer, often referred to as the "silent killer," is notoriously difficult to detect in its early stages, leading to a poor prognosis for many patients. Diagnosis is often delayed until the cancer has advanced, primarily due to its ambiguous and frequently occurring clinical symptoms. Ovarian cancer leads to more deaths than any other cancer of the female reproductive system.
View Article and Find Full Text PDFJ Tradit Complement Med
September 2024
Seasonal variations directly impact the biochemical and microbial properties of the soil, influence carbon and nutrient cycling within the soil system. Soils under tree plantation (TP) are rich in organic matter and microbial population, making them more susceptible to seasonal variation. We studied the effect of seasonal variations in soil chemical properties (pH, electrical conductivity (EC), total organic carbon (TOC), total nitrogen (TN), C/N ratio etc) and microclimate (moisture and temperature) on microbial respiration (SR), biomass, and carbon (C) utilization efficiency under 13 years old Kadamb ( Miq.
View Article and Find Full Text PDFPlant Cell Environ
April 2025
Environ Sci Pollut Res Int
August 2024
Biofuels have emerged as a promising and eco-friendly alternative to conventional fossil fuels. Biofuel sourced from rice straw (RS) and municipal solid waste (MSW), which are abundant residues from agricultural and municipal activities, present a sustainable solution to address waste management challenges. Utilizing life cycle assessment, this study quantifies the environmental advantages by assessing the reduction in greenhouse gas emissions, energy consumption, and other environmental impacts linked with employing these waste materials for biofuel production.
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