Bronchoscopic management of endobronchial hamartomas using "hot and cold" therapies - Initial experience in two patients.

Pulmonary hamartomas are the most common benign tumours of the lung and are often detected incidentally. Endobronchial hamartomas, though rare, can cause significant symptoms such as dyspnoea, haemoptysis, and recurrent respiratory infections due to bronchial obstruction. This report describes the successful bronchoscopic management of symptomatic endobronchial hamartomas in two young Indian males aged 29 and 34 years.

Digital twin for personalized medicine development.

Digital Twin (DT) technology is revolutionizing healthcare by enabling real-time monitoring, predictive analytics, and highly personalized medical care. As a key innovation of Industry 4.0, DTs integrate advanced tools like artificial intelligence (AI), the Internet of Things (IoT), and machine learning (ML) to create dynamic, data-driven replicas of patients.

Effect of Customized Oral Health Awareness Program on Knowledge and Practice of Oral Hygiene Maintenance Among Institutionalized Visually Impaired Individuals of Lucknow: A Cluster Randomized Study.

Background: Visually impaired individuals face significant challenges in maintaining oral hygiene due to reliance on visual cues. Conventional oral health education (OHE) often fails to address their needs, leading to disparities in oral health outcomes. The aim of this study was to assess and compare the effectiveness of three customized oral health education strategies-Audio only (Group 1), Audio + Braille (Group 2), and Audio + Tactile Model (Group 3)-on oral health Knowledge, Attitude, Practice (KAP), and clinical oral hygiene status among institutionalized visually impaired individuals in Lucknow, India.

Teaching, learning and evaluation of professionalism in dental education: A narrative review.

Background Professionalism is an essential competence needed in the practice of dentistry. Teaching-learning and assessment of this competency is a part of the dental curriculum. We reviewed evidence in the literature regarding methods used for teaching, learning, evaluation and assessment of professional competency in undergraduate dental education.

Retraction of "Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1".

[This retracts the article DOI: 10.1021/acsomega.2c06215.

Unveiling hepatico-duodenal ligament lymphangioma in a sickle cell disease patient: A radiological and clinical case study.

The 34-year-old female patient with sickle cell anemia had splenomegaly and excruciating stomach discomfort. radiological examinations showed a nonenhancing cystic lesion along the common bile duct, splenic infarcts, and a severely enlarged spleen with subcapsular calcifications, indicative of hepatoduodenal ligament lymphangioma. Minor ascites, borderline hepatomegaly, and a slight left-sided pleural effusion were among the related findings.

Undiagnosed complex neurological malformation in a geriatric patient presenting with seizures.

Atretic cephaloceles, grey matter heterotopia, and septo-optic dysplasia are uncommon congenital cerebral malformations commonly diagnosed in children. The case is a rare one in which atretic parietal cephalocele, grey matter heterotopia, and septo-optic dysplasia are seen concurrently and diagnosed in a 60-year-old man with a history of focal onset seizures. In contrast to their congenital origin, the patient never experienced antecedent neurodevelopmental delay or significant endocrine disturbances.

A case report unveiling spindle cell lipoma.

Spindle cell lipoma (SCL) represents an infrequent subtype of lipoma distinguished by its distinctive histopathological characteristics and tendency to localize in the subcutaneous tissues of the upper back, neck, and shoulder regions. In this report, we describe an unusual instance of SCL manifesting in the cervical area of a 62-year-old female individual. The patient exhibited a progressively enlarging painless mass situated in the left supraclavicular region for 8 years.

A silent malformation: Closed spinal dysraphism in a boy with urinary incontinence.

Spinal dysraphisms (SDs) are characterized by a heterogeneous range of congenital spinal anomalies  that arise from derivative disturbances in neural tube development. Closed spinal dysraphism, a variant, is less common and typically has a subtle clinical presentation. Timely and correct diagnosis is essential to avert chronic complications.

A case of spinal cord intramedullary cavernoma.

Rare vascular abnormalities of the central nervous system, spinal intramedullary cavernomas make up fewer than 5% of all spinal cord lesions. Symptoms are vague, making diagnosis difficult. A fast and precise diagnosis is made possible by the early detection and characterization of these lesions, which is made possible by radiological imaging, especially MRI with contrast.

A rare presentation of pleural pseudocyst in chronic calcific pancreatitis: A case report.

Chronic calcific pancreatitis (CP) is a progressive inflammatory disorder that can lead to complications in multiple organ systems. Pleural pseudocysts, a rare thoracic manifestation of chronic pancreatitis, pose significant diagnostic and therapeutic challenges. This case report highlights the presentation, diagnostic approach, and management of a patient with pleural pseudocyst associated with chronic calcific pancreatitis.

Isolated cardiac hydatid cyst: A rare but potentially life threatening presentation of hydatid infection.

Cardiac hydatid disease which is caused by the larval form of Echinococcus granuloses is the rarest yet significant presentation which is characterized by the formation of cystic lesions within the heart. It is not as common as hepatic, pulmonary hydatidosis, hence poses a unique diagnostic challenge. It may lead to severe complications like cardiac tamponade, embolism and arrhythmias.

Lobar holoprosencephaly with associated meningocele: A rare case report of a 25-year-old patient with multiple seizures.

Lobar holoprosencephaly (HPE) represents the mildest form of HPE, featuring an interhemispheric fissure extending along most of the entire midline, with the thalami remaining unfused. Lobar HPE is usually diagnosed in the prenatal stage or infancy; however, cases of adult-onset are exceedingly rare. Here, we present a 25-year-old patient who was presented with multiple episodes of seizures and was subsequently diagnosed with lobar HPE accompanied by a meningocele.

High Altitude De-acclimatization Syndrome: A Case Report.

High altitude de-acclimatization syndrome (HADAS) is a clinical entity that arises when individuals return abruptly from high-altitude environments to lower altitudes without undergoing the necessary acclimatization processes. While altitude-related illnesses have been extensively studied, HADAS remains relatively underreported and may pose diagnostic challenges due to its varied and nonspecific clinical presentation. This case report aims to shed light on the importance of recognizing HADAS as a potential consequence of inadequate acclimatization, emphasizing the need for a thorough understanding of altitude-related disorders in individuals with a history of rapid altitude changes.

Isolated splenic involvement in hydatid disease: A case report.

Isolated involvement of spleen in hydatid disease is relatively uncommon occurrence. The spleen ranks as the third most frequently affected organ in this condition, liver primarily being the most commonly affected. When the disease manifests in the spleen, it typically presents with nonspecific symptoms, complicating the diagnostic process for healthcare professionals.

Ultrasonographic evaluation of acute idiopathic scrotal wall oedema in adults.

Acute idiopathic scrotal wall oedema is an uncommon cause of acute scrotal oedema that usually affects the paediatric population and is rarely encountered in adults. It frequently goes away without the need for surgery, presenting as sudden scrotal oedema and erythema. Acute idiopathic scrotal wall oedema is diagnosed and distinguished from other scrotal disorders by clinical examination and ultrasonography, which includes the distinctive 'fountain sign'.

Interaction of cesium compounds with abundant inorganic compounds of atmosphere: Effect on cloud formation potential and settling.

Experiments were conducted in controlled laboratory conditions to determine the size-resolved CCN (Cloud Condensation Nuclei) activity of sub micrometer-sized aerosols containing nuclear fission products (CsI and CsOH) and abundant ambient inorganic aerosols ammonium sulphates ((NH)SO), ammonium chloride (NHCl), sodium nitrate (NaNO), and sodium chloride (NaCl). The presence of these atmospheric-relevant compounds internally mixed with fission product compounds has the potential to affect the capacity of ambient particulates of aerosols to absorb water and function as CCN. Once in the atmosphere, the dynamics of airborne radionuclides and subsequently their fate gets affected by dry and wet deposition processes.

mRNA Vaccines: Unlocking Potential, Exploring Applications, and Envisioning Future Horizons.

In recent years, there have been notable strides in developing mRNA vaccines, resulting in the creation of potent immunizations against diverse diseases. This review examines the most recent advancements in this field, focusing on their implications for future vaccine development. The pursuit of heightened vaccine efficacy is investigated through cutting-edge methods in adjuvant selection, delivery system optimization, and antigen selection.

``Prenatally diagnosed gastroschisis: A case report''.

Gastroschisis represents a congenital malformation characterized by the herniation of abdominal contents through a defect in the abdominal wall, predominantly situated to the right of the umbilical cord. The defect is characterized by the absence of a covering membrane, resulting in the free floating of extruded abdominal contents. Major complications associated with this condition include stillbirth, preterm delivery, and intrauterine growth restriction.

Effectiveness of teacher's training program for tobacco control in schools of Lucknow: A Quasi-experimental study.

Introduction: Teachers play a crucial role in influencing the attitudes and behaviors of their students. Their knowledge, attitude, and practice towards tobacco use, have a direct impact on strict implementation of School Tobacco Control Policies. The present study aimed to assess the effectiveness of the teacher's training program, for tobacco control measures in schools of Lucknow.

MRI appearance of Bochdalek's flower basket in a patient with bilateral hippocampus infarct.

The occurrence of isolated bilateral hippocampus infarct is extremely rare and is thought to be associated with a number of etiologies, including ischemia, infection, paraneoplastic syndromes, seizures, drug addiction, etc. The presented manuscript depicts a case of a 28-year-old male patient who has been a chronic alcoholic for the past 4 years and, on imaging, was found to have a bilateral hippocampal infarct in isolation. Also, the manuscript presents the appearance of the magnetic resonance imaging (MRI) of Bochdalek's flower basket, which is an anatomical variant of the choroid plexus in the fourth ventricle.

Challenging the giant: A case report on a huge sacrococcygeal chordoma and its radiological insights.

Sacral chordoma is a rare osseous tumor of malignant origin. Remnants of the notochord in the region of sacrum and coccyx is said to be the origin of these tumors. Patients generally have delayed presentation, which is responsible for larger tumor size.