The Influence of Dimensional Parameters on the Characteristics of Magnetic Flux Concentrators Used in Tunneling Magnetoresistance Devices.

Measuring weak magnetic fields proposes significant challenges to the sensing capabilities of magnetic field sensors. The magnetic field detection capacity of tunnel magnetoresistance (TMR) sensors is often insufficient for such applications, necessitating targeted optimization strategies to improve their performance in weak-field measurements. Utilizing magnetic flux concentrators (MFCs) offers an effective approach to enhance TMR sensitivity.

Combined lifestyle, childhood trauma and depressive symptoms in adults with subthreshold depression: a prospective cohort study.

Aims: Existing evidence on the association between combined lifestyle and depressive symptoms is limited to the general population and is lacking in individuals with subthreshold depression, a high-risk group for depressive disorders. Furthermore, it remains unclear whether an overall healthy lifestyle can mitigate the association between childhood trauma (CT) and depressive symptoms, even in the general population. We aimed to explore the associations of combined lifestyle, and its interaction with CT, with depressive symptoms and their subtypes (i.

Grade-level differences in the association between cumulative family risk factors and problematic smartphone use among Chinese adolescents.

Background: Globally, more adolescents are engaged in problematic smartphone use (PSU), but there is scant research on the impact of family risk factors on PSU. This study aimed to investigate the independent and cumulative effects of various family risk factors on adolescents' PSU and to determine whether these associations differ across grade level.

Methods: Data were drawn from the 2023 National School-based Chinese Adolescents Health Survey, with 20,361 adolescents (mean age: 15.

Characteristics of adult membranous nephropathy patients with capillary co-deposition of IgG and IgA.

Background: Membranous nephropathy (MN) is characterized by subepithelial immune complex deposits of IgG, particularly anti-Phospholipase A2 Receptor (anti-Pla2r). However, presence of IgA co-deposition along subepithelial region of the glomerular capillary walls has not been extensively investigated.

Methods: Five hundred thirty-one biopsy-proven MN patients from Huashan Hospital were screened for capillary IgA deposition.

Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.

Background: Both recent negative life events (RNLEs) and lifestyle factors were associated with depressive symptoms, but it is unclear whether adopting a healthy lifestyle can mitigate the association between RNLEs and depressive symptoms. We aim to explore the modifying role of adopting a healthy lifestyle in the association between RNLEs and depressive symptoms.

Method: A cross-sectional study was conducted among 4,278 participants aged 18-70 years.

Association between living arrangement and psychological well-being among patients with major depressive disorder: the moderating role of body mass index.

Background: Major depressive disorder (MDD) is highly prevalent globally, significantly impacting psychological well-being (PWB). Herein, we aim to evaluate the impact of different living arrangements on PWB in individuals with MDD and explore the potential moderating role of BMI in this relationship.

Methods: Participants with MDD were recruited from a specialist mental health hospital between December 2019 and April 2023.

A High-Sensitivity, Low-Noise, and Low-Hysteresis Tunneling Magnetoresistance Sensor Based on Structural Optimization of Magnetic Tunnel Junctions.

Accurate measurement of magnetic fields holds immense significance across various disciplines, such as IC circuit measurement, geological exploration, and aerospace. The sensitivity and noise parameters of magnetic field sensors play a vital role in detecting minute fluctuations in magnetic fields. However, the current detection capability of tunneling magnetoresistance (TMR) is insufficient to meet the requirements for weak magnetic field measurement.

Relapse Risk in Patients with Membranous Nephropathy after Inactivated COVID-19 Vaccination.

Background: Although there have been reports of relapse or worsening of membranous nephropathy after receiving vaccines against coronavirus disease 2019 (COVID-19), the causal relationship or association between them has not been established. This study aimed to investigate the occurrence of relapse or worsening of membranous nephropathy following inactivated COVID-19 vaccination.

Methods: Patients who had been diagnosed with membranous nephropathy before receiving their first dose of vaccination, or before March 1, 2021, for unvaccinated patients, were included in the study.

A large-scale integrated transcriptomic atlas for soybean organ development.

Soybean is one of the most important crops globally, and its production must be significantly increased to meet increasing demand. Elucidating the genetic regulatory networks underlying soybean organ development is essential for breeding elite and resilient varieties to ensure increased soybean production under climate change. An integrated transcriptomic atlas that leverages multiple types of transcriptomics data can facilitate the characterization of temporal-spatial expression patterns of most organ development-related genes and thereby help us to understand organ developmental processes.

HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding.

Introduction: The H9N2 avian influenza virus is widely disseminated in poultry and poses a zoonotic threat, despite vaccination efforts. Mutations at residue 198 of hemagglutinin (HA) are critical for antigenic variation and receptor-binding specificity, but the underlying molecular mechanisms remain unclear. This study explores the molecular mechanisms by which mutations at the HA 198 site affect the antigenicity, receptor specificity, and binding affinity of the H9N2 virus.

Moderation of sex in the Association between School Bullying Behaviors and problematic gaming among Chinese adolescents: a cross-sectional study.

Introduction: Problematic gaming (PG) is a serious issue among adolescents worldwide, and there is evidence suggesting that school bullying behaviors may be associated with increased rates of PG. This study aimed to examine the associations between school bullying behaviors and PG among adolescents, with a focus on sex effects.

Methods: A total of 20,197 participants were recruited from the 2023 School-based Chinese Adolescents Health Survey.

Progranulin-dependent repair function of regulatory T cells drives bone-fracture healing.

Local immunoinflammatory events instruct skeletal stem cells (SSCs) to repair/regenerate bone after injury, but mechanisms are incompletely understood. We hypothesized that specialized Tregs are necessary for bone repair and interact directly with SSCs through organ-specific messages. Both in human patients with bone fracture and a mouse model of bone injury, we identified a bone injury-responding Treg subpopulation with bone-repair capacity marked by CCR8.

Obinutuzumab treatment for membranous nephropathy: effectiveness and safety concerns during the COVID-19 pandemic.

Background: Obinutuzumab is a humanized and glycoengineered anti-CD20 monoclonal antibody that has been shown to induce more profound B-cell depletion than rituximab. The effectiveness and safety of obinutuzumab in the treatment of membranous nephropathy remain unclear.

Methods: This was a retrospective study conducted in Huashan Hospital, Fudan University between 1 December 2021 and 30 November 2023.

Diet-related diseases mediate the effect of masticatory function on premature death in older adults.

Aim: Although poor oral health has been a potentially modifiable risk for mortality, the precise association between functional tooth units (FTUs) and premature death as well as the underlying mechanisms remains unclear.

Methods: This study used data from the National Health and Nutrition Examination Survey (NHANES) 2009-2018. Mortality details were obtained from the National Death Index (NDI).

sp. nov. and sp. nov., isolated from kelp seedlings.

Two novel rod-shaped, strictly aerobic, non-motile and Gram-stain-negative bacterial strains, designated SDUM040013 and SDUM040014, were isolated from kelp seedlings in Weihai, PR China. Cells of strain SDUM040013 were 0.3-0.

Association between masticatory function and depression in older adults: Results from NHANES 2009 to 2018.

Aim: Depression is prevalent among older adults. Although the number of missing teeth is considered to be associated with depression, the relationship between masticatory function, which is usually indicated by functional tooth units (FTUs), and depression in older adults remains unclear.

Materials And Methods: This study used data from the National Health and Nutrition Examination Survey (NHANES) 2009-2018.

Impact of periodontitis on type 2 diabetes: a bioinformatic analysis.

Background: Periodontitis is strongly associated with type 2 diabetes (T2D) that results in serious complications and mortality. However, the pathogenic role of periodontitis in the development of T2D and the underlain mechanism have not been fully elucidated.

Methods: A Mendelian randomization (MR) was performed to estimate the causality between two diseases.

Transcriptome analysis reveals PRKCA as a potential therapeutic target for overcoming cisplatin resistance in lung cancer through ferroptosis.

Cisplatin-based chemotherapy is the current standard care for lung cancer patients; however, drug resistance frequently develops during treatment, thereby limiting therapeutic efficacy.The molecular mechanisms underlying cisplatin resistance remain elusive. In this study, we conducted an analysis of microarray data from the Gene Expression Omnibus (GEO) database under the accession numbers GSE21656, which encompassed expression profiling of cisplatin-resistant H460 (DDP-H460)and the parental cells (H460).

Case report: BTK inhibitors is effective in type II mixed cryoglobulinemia with wild-type MyD88.

This study presents two cases of type II mixed cryoglobulinemia. One case is essential, while the other is presumably associated with hepatitis B virus (HBV) infection. Both patients tested positive for monoclonal IgMκ, but negative for MyD88 mutation.