Surgical and Voice Outcomes of Office-Based Vocal Fold Dysplasia and Leukoplakia Surgery: A Systematic Review.

Objective: To investigate the surgical and voice quality outcomes of office-based laryngeal surgery for patients with laryngeal dysplasia and leukoplakia.

Data Sources: PubMed, Google scholar, and Cochrane databases.

Review Methods: Three independent investigator search databases for studies reporting surgical or voice quality outcomes of patients treated with office-based surgery for vocal fold dysplasia or leukoplakia.

Micro- and Nanoplastic Toxicity in Upper Respiratory Tract: A Scoping Review.

Objectives: To review the current literature findings dedicated to the toxicity of nano- and microplastics (NMPs) in the upper respiratory tract.

Data Sources: PubMED, Cochrane Library and Embase databases.

Review Methods: Three independent investigators conducted the literature search for the documentation and toxicity of NMP in the upper respiratory tract according to the PRISMA statements.

Prognostic Significance of Neutrophil-Lymphocyte Ratio in Salivary Gland Neoplasms: A Systematic Review.

ImportanceSalivary gland tumors (SGTs) are rare and heterogeneous, necessitating improved prognostic tools to optimize patient management.ObjectiveTo evaluate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in distinguishing between benign and malignant SGTs, identifying tumor stage, and predicting survival and adverse events.DesignSystematic review conducted according to PRISMA guidelines.

Impact of the Microbiome on Onset and Prognosis of Oropharyngeal Squamous Cell Carcinoma.

Introduction: Recent attention to the role of the microbiome in oral cancer has prompted investigations into its potential contribution to oropharyngeal squamous cell carcinoma (OPSCC), given their anatomical and immunological overlap. However, consistent microbial patterns have not been identified across studies.

Methods: A systematic review, following PRISMA guidelines, examined studies on the role of the oral/oropharyngeal microbiome in OPSCC development, including its statistical relevance in cancer occurrence and prognosis.

Patient Perceptions of Artificial Intelligence in Otolaryngology-Head and Neck Surgery: An International Study.

Objective: To investigate the demographic determinants of patient perception toward the role of artificial intelligence (AI) in otolaryngology-head and neck surgery care.

Methods: Outpatients consulting in otolaryngology-head and neck surgery departments of 18 hospitals were surveyed about the perception of the role of AI in health care. The results were analyzed according to the age, gender, patient use of technology, and the level of education.

Transoral robotic surgery for salivary carcinomas of the base of tongue: a multicenter REFCOR study.

Transoral robotic surgery (TORS) allows minimally invasive surgical access to the oropharynx. Its benefits are well documented for squamous cell carcinomas, but not for salivary carcinomas. The aim of this study was to describe the French experience of TORS regarding salivary gland carcinomas of the base of tongue (BOT).

Origin and In-Office Treatment of Retrograde Cricopharyngeus Dysfunction.

Importance: Retrograde cricopharyngeus dysfunction (R-CPD) is an emerging disorder associated with disabling symptoms. The origin of R-CPD remains unknown.

Objective: To investigate the development of symptoms, diagnosis approach, and therapeutic outcomes of R-CPD in patients treated with in-office botulinum toxin injection (BTI) into the cricopharyngeus.

Functional and oncological outcomes of transoral laser versus robotic surgery in supraglottic squamous cell carcinoma.

Objective: To compare the surgical, functional and oncological outcomes of Transoral Laser Microsurgery (TLM) and Transoral Robotic Surgery (TORS) for the treatment of supraglottic squamous cell carcinoma.

Study Design: Retrospective case series with prospective data.

Settings: Tertiary Academic Medical Center.

Voice Quality After Anterior Commissure Cordectomy Versus Marginal Cordectomy for cT1 Glottic Carcinoma: A Case-Series.

Objectives: To compare the presurgical to postsurgical voice quality (VQ) outcomes of types I, II, III, and VI transoral laser cordectomies (TLC).

Study Design: Prospective uncontrolled study.

Setting: Multicenter study.

Debunking the Myth: Should Pierre Robin be Credited for Defining the Pierre Robin Sequence?

The Pierre Robin Sequence is a rare craniofacial malformation that invariably combines retrognathism, glossoptosis, and upper airway obstruction, with a prevalence ranging from 1 in 8000 to 1 in 14,000 newborns. Although formally described by the French physician Pierre Robin in 1923, older and even ancient as far back as the Babylonian times, descriptions have been identified. Dr Pierre Robin's perspicacity lay in putting up a treatment for the patients presenting those symptoms.

Therapeutic strategy for advanced stages salivary carcinomas of the tongue: A multicenter REFCOR study.

Introduction: Salivary carcinomas of the tongue represent a therapeutic challenge as their radical excision is particularly mutilating. We aimed to study the oncologic and functional outcomes of advanced stages salivary carcinomas of the tongue.

Materials And Methods: This retrospective multicentric study, based on the French national network on rare head and neck cancers (REFCOR), included all patients with a T3-T4 salivary carcinoma of the tongue, diagnosed between January 2009 and December 2018.

Impact of facial nerve resection in parotid cancer abutting the facial nerve without preoperative paralysis: A multicentric propensity score-based analysis.

Objectives: The management of the facial nerve (FN) is a major issue in parotid cancer, especially when there is no preoperative facial palsy and FN invasion is discovered intraoperatively. The aim of this study was to assess the impact of FN resection in patients with parotid cancer abutting the FN, without pretreatment facial palsy, using a propensity score matching.

Materials And Methods: Data from all patients treated between 2009 and 2020 for a primary parotid cancer abutting or invading the FN but without pretreatment facial palsy were extracted from the national multicentric REFCOR database.

Is tetrodotoxin intoxication the cause of "zombi voice" in Haiti?

Objective: Zombification, a magical and religious process in Haiti, has been scientifically studied and remains relevant. Originating from the convergence of African, Caribbean, and Christian rites, it involves a comatose trance, transforming individuals into living dead through Voodoo practices. Haitian zombies consistently exhibit a preserved expression marked by a nasal voice, a result of nasalization-using nasal cavities as resonators during phonation.

World premiere: transoral robot-assisted excision for nasopharyngeal ectopic pituitary adenoma.

Background: Pituitary adenoma (PA), though rare, has seen increased incidence with widespread MRI use, enabling incidental diagnosis. Prevalence is approximately 1 case per 1000 in the general population. PAs are benign neoplasms, constituting 10 to 20% of intracranial tumours.

One hundred fifty years of total laryngectomies.

The inaugural total laryngectomy in history was conducted by Billroth in 1873. Nevertheless, significant enhancements to the technique were achieved through the contributions of Gluck, Sorensen, and various other surgeons. Throughout the twentieth century, advancements in anesthesia, infectious disease, hospital hygiene, antibiotic therapy, resuscitation, and the expertise of numerous laryngologists elevated total laryngectomy to a pivotal surgical intervention in head and neck surgery.

"Ice cream cone" design of forearm free flap for orbital exenteration reconstruction.

Backgrounds: Reconstruction post-orbital exenteration serves the dual purpose of expediting healing, laying the groundwork for cosmetic restoration, and minimising complications such as orbitosinusal fistulae. The aim of this study was to introduce a modified "Ice cream cone" (ICC) design of the Radial Forearm Free Flap (RFFF) technique used for reconstruction of orbital exenteration cavity, along with the oncological, functional, and aesthetic outcomes.

Methods: The authors conducted a retrospective study between January 2005 and December 2020.

Laryngeal microsurgery under Transnasal Humidified Rapid Insufflation Ventilatory Exchange.

Objective: Since 2015, Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE) has been used in general anesthesia for preoxygenation or difficult exposure airway management. Its use offers new opportunities in laryngology. THRIVE increases apnea time and frees the access to the upper airway.

Immunosuppressive protocols after laryngeal transplantation: a systematic review.

Backgrounds: Larynx transplantation has been successfully performed four times, in 1998, 2010, 2015 and 2023 remained the ultimate goal of voice, feeding and breathing rehabilitation.

Objective: Immunosuppressive protocols used during the previous successful larynx allotransplantation are detailed.

Material And Methods: A systematic review of the literature on PUBMED/Medline, Cochrane and Embase was conducted.

Three-dimensional reconstruction of King Henri IV's paranasal sinuses and mastoid cells.

Purpose: The preserved head of King Henri IV of France (life 1553-1610, reign 1589-1610) has survived to the present day thanks to high-quality embalming and favorable conservation conditions. The aim of this study was to examine Henry IV's upper resonant cavities and mastoids using an original and innovative forensic three-dimensional segmentation method.

Methods: The paranasal sinuses and mastoid cells of King Henri IV of France were studied by cross-referencing available biographical information with clinical and flexible endoscopic examination and computed tomography (CT-scan) imaging.

Over 132 Years Ago, the Inaugural Immunotherapy Treated Its First Head and Neck Cancer Patient.

Immunotherapy in oncology has a more extensive history than is commonly perceived. Rooted in the observations and experiences of multiple physicians in the late 19th century, immunological interventions are currently integral to the oncological therapeutic repertoire. This article seeks to delineate the evolution of cancer immunotherapy, tracing its inception in 1891 with the pioneering work of an American surgeon, William B.

Hypothesis of a CD137/Eomes activating axis for effector T cells in HPV oropharyngeal cancers.

Chronic Human Papilloma Virus (HPV) infection is supplanting alcohol and tobacco intoxications as the leading cause of oropharyngeal cancer in developed countries. HPV-related squamous cell carcinomas of the oropharynx (HPV + OSC) present better survival and respond better to radiotherapy and chemotherapy. Regulatory T cells (T) are mainly described as immunosuppressive and protumoral in most solid cancers.