Is the Botulinum Toxin Injection Into the Cricopharyngeal Sphincter Precipitate Laryngopharyngeal Reflux Symptoms in Patients With Retrograde Cricopharyngeal Dysfunction?

Objective: To investigate the potential relationship between retrograde cricopharyngeal dysfunction (R-CPD) and laryngopharyngeal reflux disease (LPRD) at baseline and whether cricopharyngeal sphincter paralysis botulinum toxin injection (BTI) is associated with an increase of LPRD symptoms in treated R-CPD patients.

Methods: Patients with clinical diagnosis of R-CPD were prospectively recruited from two European hospitals. Controls included individuals unable to burp without troublesome symptoms (CT1) and healthy subjects able to burp (CT2).

Therapeutic Outcomes of Vocal Fold Botulinum Toxin Injections for Exercise-Induced Laryngeal Obstruction.

Objective: To investigate the effectiveness of vocal fold botulinum toxin injection (BTI) for treating patients with the glottic form of exercise-induced laryngeal obstruction (EILO).

Methods: The outcomes of 13 patients treated with BTI for a confirmed diagnosis of EILO between May 2017 and July 2024 were retrospectively analyzed. Electromyography-guided bilateral BTI (1.

In-Office Transnasal Botulinum Toxin Injections for Retrograde Cricopharyngeal Dysfunction.

This paper introduces a new transnasal in-office technique for botulinum toxin injection into the cricopharyngeal muscle of patients with retrograde cricopharyngeal dysfunction (R-CPD).

Etiology, Clinical Presentation, and Management of Retrograde Cricopharyngeus Dysfunction: A Systematic Review.

ImportanceThe retrograde cricopharyngeus dysfunction (R-CPD) is an emerging topic in otolaryngology, gastroenterology, and primary care.ObjectiveTo review the current literature about the etiology, clinical presentation, and management of retrograde cricopharyngeus dysfunction (R-CPD).DesignSystematic review.

Origin and In-Office Treatment of Retrograde Cricopharyngeus Dysfunction.

Importance: Retrograde cricopharyngeus dysfunction (R-CPD) is an emerging disorder associated with disabling symptoms. The origin of R-CPD remains unknown.

Objective: To investigate the development of symptoms, diagnosis approach, and therapeutic outcomes of R-CPD in patients treated with in-office botulinum toxin injection (BTI) into the cricopharyngeus.

Is tetrodotoxin intoxication the cause of "zombi voice" in Haiti?

Objective: Zombification, a magical and religious process in Haiti, has been scientifically studied and remains relevant. Originating from the convergence of African, Caribbean, and Christian rites, it involves a comatose trance, transforming individuals into living dead through Voodoo practices. Haitian zombies consistently exhibit a preserved expression marked by a nasal voice, a result of nasalization-using nasal cavities as resonators during phonation.

Incidence and risk factors for secondary extralaryngeal dystonia in patients with laryngeal dystonia.

Background And Objectives: Laryngeal dystonia (LD) is a focal dystonia affecting adductor and/or abductor muscles of the larynx. It can be isolated or may spread to extra laryngeal muscles. The aim of this study was to report the characteristics of LD over time in a large single-center study with a long follow-up.

Oromandibular Dystonia: A Clinical Examination of 2,020 Cases.

The goal of this study is to better characterize the phenotypic heterogeneity of oromandibular dystonia (OMD) for the purpose of facilitating early diagnosis. First, we provide a comprehensive summary of the literature encompassing 1,121 cases. Next, we describe the clinical features of 727 OMD subjects enrolled by the Dystonia Coalition (DC), an international multicenter cohort.

Positive Effects of Local Botulinum Toxin Injection and Colchicine for Complicated Chronic Recurrent Parotitis: A Case Report.

Chronic recurrent parotitis (CRP) is a rare affliction of unknown cause characterized by recurrent episodes of unilateral or bilateral nonobstructive and nonsuppurative inflammation of the parotid glands. Management of CRP is not standardized, and attempts at treatment often fail. We report a case of a 29-year-old female patient with CRP for 13 years, with recurrent acute episodes, complicated with a collection and cutaneous fistula, refractory to repeated courses of corticosteroids and antibiotics.

Oromandibular Dystonia: Demographics and Clinical Data from 240 Patients.

Objective: To report demographic data from a large cohort of patients with oromandibular dystonia (OMD).

Methods: This is a retrospective review of patients with OMD referred to our institution between 1989 and 2015. Demographic (age of onset, gender, and familial history of dystonia) and clinical (type of OMD, associated dystonia, and etiology of dystonia) data were collected from a cohort of 240 individuals.