Mapping the pangenome of sulfate reducing bacteria: core genes, plasticity, and novel functions in Desulfovibrio spp.

The pangenome of sulfate reducing bacteria represents a genetic reservoir that deciphers the intricate interplay of conserved and variable elements driving their ecological dominance, evolutionary adaptability, and industrial relevance. This study introduces the most comprehensive pangenome analysis of the genus Desulfovibrio till date, incorporating 63 complete and high-quality genomes using the Partitioned Pangenome Graph of Linked Neighbors (PPanGGOLiN) pipeline. The structure and dynamics of core gene families were investigated through gene ontology, KEGG pathway mapping, and gene network analyses, shedding light on the functional organization of the Desulfovibrio genomes.

Imidazole-, Triazole-, and Tetrazole-Based High-Energy Ionic Liquids.

Ionic liquids (ILs) are unique materials made of cations and anions that have seen a resurgence in recent decades owing to their wide applicability. The utility of ILs in the field of high-energy molecules and energetic materials has been widely studied. These compounds have an enormous reservoir of chemical energy that can be liberated under specified conditions.

Progress In the Chemistry and Pharmacology of Isoindolin-1-One Scaffolds.

Isoindolin-1-one scaffolds have emerged as privileged structures in medicinal and synthetic chemistry due to their diverse biological activities and synthetic accessibility. This review comprehensively highlights the recent advancements in the development of synthetic methodologies for constructing isoindolin-1-one cores, encompassing both metal-catalyzed and metal-free approaches. Key strategies include the electrochemical method, transition metal-catalyzed synthesis, radical and oxidant-driven metal-free method, acid-catalyzed and multicomponent method, ring opening method, and ultrasound-assisted method of synthesis.

Ion Conduction Dynamics, Characterization, and Application of Ionic Liquid Tributyl Methyl Phosphonium Iodide (TMPI)-Doped Polyethylene Oxide Polymer Electrolyte.

The increasing demand for high-performance energy storage devices has stimulated interest in advanced electrolyte materials. Among them, ionic liquids (ILs) stand out for their thermal stability, wide electrochemical windows, and good ionic conductivity. When doped into polymeric matrices, these ionic liquids form hybrid polymeric electrolytes that synergize the benefits of both liquid and solid electrolytes.

Optimizing intelligent reflecting surface assisted visible light communication networks under blockage and practical constraints using TLBO for IoT applications.

Wireless communication systems can enhance their capabilities by exploring new opportunities and addressing emerging challenges through the integration of the Internet of Things (IoT) in 6G networks. Visible Light Communication (VLC) stands out as a promising wireless access technology for IoT devices. This paper presents a novel Teaching-Learning-Based Optimization (TLBO) optimized Intelligent Reflecting Surface (IRS)-assisted VLC system aimed at maximizing Signal-to-Noise Ratio (SNR) and enhancing illuminance uniformity.

Incidence and Outcome of HTG-AP at a Tertiary Care Center in Eastern India: A Retrospective Analysis.

Background: Hypertriglyceridemia-associated pancreatitis (HTG-AP) is a notable cause of acute pancreatitis (AP) due to high triglyceride (TG) levels. It is associated with more complications than non-hypertriglyceridemia-associated acute pancreatitis (non-HTG AP). Current treatments include supportive care, insulin infusion, and plasmapheresis.

Trends in Dermato-polymyositis Mortality, 1999-2022: A Nationwide Population-based Study, United States.

Objective: We evaluated trends in dermato-polymyositis (DPM) mortality relative to all-cause mortality in the United States, 1999-2022.

Methods: We used the Center for Disease Control and Prevention's databases (Multiple Causes of Death for 1999-2020 and Provisional Mortality Statistics for 2021 and 2022) to obtain death counts for DPM and non-DPM (all causes other than DPM). We calculated age-standardized mortality rates (ASMR) for both groups and computed the ratio of DPM-ASMR to non-DPM-ASMR for each of the 24 years.

Developing a Feeding Module with a Blend of Garlic Oil and Cinnamon Bark for Enhancing Antioxidant Status and Immunity of Murrah Buffalo () with an Improvement in Feed Efficiency and Reduced Methane Emissions.

The experiment was designed to evaluate the consequence of a blend of garlic oil and cinnamon bark powder administration on growth performance, nutrient digestibility, immunity, antioxidant status and methane emission in Murrah buffalo (). Sixteen buffalo calves were divided into two groups in a completely randomised design. The first group (CONT) was fed a basal diet of wheat straw, green oats and concentrate mixture, whereas the second group (GOCB) received feeds as per the CONT along with a blend of garlic oil and cinnamon bark powder (0.

Lower Limb Orthopedic Anesthesia: A Randomized Trial Comparing Ropivacaine and Bupivacaine for Sensory-Motor Block and Hemodynamic Stability.

Background Spinal anesthesia is the preferred anesthetic technique for lower limb orthopedic surgeries due to its efficacy, rapid onset, and favorable safety profile. While bupivacaine has long been considered the gold standard, its cardiovascular side effects have prompted interest in ropivacaine, a newer agent with a better safety margin. This study compares the sensory-motor block characteristics and hemodynamic stability of hyperbaric ropivacaine (0.

Phytochemistry and applications of glycosides from Syzygium genus: A mini review.

One of the biggest genera of flowering plants in the Myrtaceae family is Syzygium genus. This is highly diverse and grown for a variety of uses, including the production of colorful, delicious, and meaty fruits. Each species of plant contains a variety of phytochemical elements, including flavonoids, terpenoids, tannins, glycosides, and phenolics, in its leaves, seeds, fruits, bark, stem bark, and flower buds.

Pathogen-Informed Strategies for Durable Resistance in Rice: Lessons from Bacterial Blight.

Bacterial blight (BB), caused by pathovar (), is a major rice disease in Asia and Africa. possesses virulence factors for pathogenicity and race differentiation that complicate resistance breeding of rice. The availability of 48 BB resistance () genes () portends the selection of genes for broad and durable resistance.

Molecular docking and molecular dynamics simulation studies of thiazole-coumarin and thiazole-triazole conjugates against M and ACE2 receptor for SARS COV-2.

The recent COVID-19 pandemic, which caused severe respiratory infections and multiple organ failure leading to death, has drawn the attention of researchers around the world. Several vaccines are available for protection against SARS-CoV-2. However, the frequent changes in its viral genome have raised concerns about the efficacy of current vaccines.

Transdifferentiation of Multiple Myeloma into Histiocytic Sarcoma: Case Report of a Highly Unusual Phenomenon.

Introduction: Transdifferentiation of multiple myeloma (MM) into histiocytic sarcoma (HS) is exceptionally rare. We report a unique case, confirming this phenomenon through cytogenetics and molecular analyses.

Case Presentation: A 46-year-old woman with high-risk light chain MM developed extramedullary disease despite multiple lines of therapy.

Estimating gestational age using placental thickness and fetal weight.

The correlation between placental thickness, gestational age and fetal weight across different stages of pregnancy is of interest. Hence, 187 women (11-40 weeks gestation) at Maa Vindhyavasini Autonomous State Medical College and SMMH Medical College in India participated in this study. Results showed that mean placental thickness increased with gestational age (2.

Optimizing sowing time and weather conditions for enhanced growth and seed yield of chia ( L.) in semi-arid regions.

Background: Climate influenced weather events, especially during the flowering, grain filling, and maturity stages, can adversely influence crop yield and quality. Therefore, understanding how the phenological behaviour and yield potential of new crops such as chia are influenced by weather and sowing dates is crucial for maximizing crop yield. This study aimed to assess the impact of sowing dates on the flowering behaviour, and yield attributes of chia morphotypes, as well as to identify optimal weather conditions for achieving higher yields.

A critical review on the properties and applications of bulk micro and nanobubbles for the degradation of organic pollutants in wastewater treatment.

The presence of persistent organic pollutants in wastewater streams has presented significant challenges towards their removal. In the recent decade, bulk micro (1-100 μm) and nanobubble (50-150 nm) (MNB) technology has exhibited technological advancements via integration of MNB technology in degrading organic pollutants from wastewater streams. The present review critically analyses the physico-chemical properties such as stability, zeta potential, mass transfer rates, rising velocity and size distribution of MNBs.

India's medical devices policy: exploring determinants in business ecosystem for export excellence.

Purpose: This paper attempts to elucidate the fundamental determinants-both enablers and impediments-that shape a resilient business ecosystem for the medical devices sector in India, with a particular emphasis on sustainable export endeavours under the ambit of the Medical Devices Policy 2023.

Design/methodology/approach: This study dives into India's medical device export firms, analysing factors influencing their performance. By reviewing relevant literature, it identifies regulatory, manufacturing, marketing, distribution and import-related factors.

Structural-morphological insights into optimization of hydrothermally synthesized MoSe nanoflowers for improving supercapacitor applications.

The present work reports a clear and improved hydrothermal methodology for the synthesis of MoSe nanoflowers (MNFs) at 210 °C. To observe the effect of temperature on the fascinating properties, the process temperature was modified by ±10 °C. The as-prepared MNFs were found to consist of 2D nanosheets, which assembled into a 3D flower-like hierarchical morphology van der Waals forces.

Herbicide and irrigation management options in conventionally-tilled wheat: deciphering water and energy budgeting, and grain and monetary output in north-Indian plains.

In South Asia, declining water tables due to increased irrigation and labor shortages for manual weeding pose significant challenges for wheat production. Additionally, herbicide resistance, often resulting from poor management practices, further complicates weed problems. The objective of this study was to assess the impacts of traditional irrigation regimens (IRs) and herbicide application on wheat crops.

Longitudinal strain enhancement and bending deformations in piezoceramics.

Piezoelectric materials directly convert between electrical and mechanical energies. They are used as transducers in applications such as nano-positioning and ultrasound imaging. Improving the properties of these devices requires piezoelectric materials capable of delivering a large longitudinal strain on the application of an electric field.

Evaluating the Impact of Elective Endotracheal Tube Replacement on Postoperative Outcomes in Esophageal Atresia: A STROBE-guided Study.

Background: Elective ventilation and paralysis have been shown to decrease the anastomosis-related complications following primary repair of esophageal atresia (EA). Repeated endotracheal tube (ETT) block and replacement can increase these complications. We evaluated the results of our strategy of electively changing the ETT just before shifting the patient to the postoperative ward for elective ventilation.

Identification of Pre-Heart Failure in Early Stages: The Role of Six Stages of Heart Failure.

Despite increased availability of effective drug therapy for treatment of heart failure (HF), the morbidity and mortality in chronic heart failure (CHF) are unacceptably high. Therefore, there is an urgent need to ascertain new imaging techniques to identify early sub-clinical forms of cardiac dysfunctions, to guide early relevant treatment. It seems that all the behavioral risk factors-such as tobacco, alcoholism, Western-type diet, sedentary behavior and obesity, emotional disorders, and sleep disorder are associated with early cardiac dysfunction, which may be identified by speckle-tracking echocardiography (STE).

Artificial intelligence chatbots versus traditional medical resources for patient education on "Labor Epidurals": an evaluation of accuracy, emotional tone, and readability.

Background: Labor epidural analgesia is a widely used method for pain relief in childbirth, yet information accessibility for expectant mothers remains a challenge. Artificial intelligence (AI) chatbots like Chat Generative Pre-Trained Transformer (ChatGPT) and Google Gemini offer potential solutions for improving patient education. This study evaluates the accuracy, readability, and emotional tone of AI chatbot responses compared to the American Society of Anesthesiologists (ASA) online materials on labor epidurals.