Kinesin KIF16B Participates in G2/M Transition and Microtubule Dynamics via Aurora A-PLK1 in Oocyte Meiosis.

KIF16B is a member of the kinesin-3 family of motor proteins, which facilitates processes such as vesicle transport, microtubule dynamics, and organelle function during mitosis. In this study, we explored the role of KIF16B in meiosis. Our findings indicate that KIF16B is involved in the meiotic G2-M transition and spindle assembly in oocytes.

Autophagy induced by Porphyromonas gingivalis aggravates esophageal squamous cell carcinoma via YAP/TAZ-miR-21-5p axis.

Porphyromonas gingivalis (P. gingivalis), a keystone pathogen in adult periodontitis, is linked to an increased risk of many cancers. Although autophagy stimulated by P.

Anti-windup control of discrete time switched delay systems with actuator saturation and failures.

The problem of L-gain analysis and anti-windup (AW) fault-tolerant controller design of a class of time-varying delay discrete-time switched systems with actuator saturation and external disturbances is investigated by using the multiple Lyapunov functionals method. Firstly, for each subsystem, we construct an AW fault-tolerant controller consisting of a dynamic state feedback (DSF) controller and an AW compensator, such that the closed-loop system with actuator faults can meet the disturbance attenuation performance index and ensure that the state trajectories of the closed-loop system are bounded under the action of external disturbances. Then, the problem of estimating the allowable interference capacity is transformed into a constrained optimization problem.

PSME2 promotes malignant progression through autophagy modulation via IL-6/STAT3 signaling pathway in esophageal squamous cell carcinoma.

Aims: This study aims to investigate the expression, clinical relevance, and functional roles of PSME2 in esophageal squamous cell carcinoma (ESCC).

Materials And Methods: The biomarkers for ESCC were identified through comprehensive analysis of publicly available mRNA transcriptome data obtained from TCGA and GEO databases. The mRNA and protein expression levels of PSME2 in ESCC were validated using two independent cohorts of ESCC samples.

Association of greenness exposure with serum vitamin D status and effects of ambient particulate matter among pregnant women in early pregnancy.

Adequate vitamin D is essential for the health of both the mother and fetus, and it can be influenced by environmental factors. However, research on the associations between greenness exposure and vitamin D concentrations during pregnancy is limited. This retrospective birth cohort study, conducted from 2014 to 2018, assessed the greenness of residences using the satellite-derived normalised difference vegetation index (NDVI).

Luminol electrochemiluminescence gel device for accurate and rapid monitoring of trace radon.

Background: Radon, the most common natural radioactive gas in the environment, is widely regarded as the second leading cause of lung cancer after smoking. However, conventional measurement techniques for radon concentration analysis are relatively lengthy and susceptible to interference from other environmental factors. Therefore, it is necessary to develop innovative and sustainable methods for the accurate and rapid analysis of radon concentrations, which has notable importance in the field of public health.

Investigating the causal relationship between rheumatoid arthritis and cardiovascular disease: A Mendelian randomization study.

Objective: Previous research has revealed a positive correlation between rheumatoid arthritis (RA) and cardiovascular diseases, but the causal relationship is unclear. This study applies Mendelian randomization to examine whether RA causally contributes to the likelihood of various cardiovascular diseases, such as heart failure, coronary artery disease, and atrial fibrillation.

Methods: Using genome-wide association data, we conducted a univariable MR (UVMR) analysis to evaluate the causal impact of RA on CVD, primarily utilizing the inverse variance weighted method.

Zirconium-doped iron oxide nanoparticles for enhanced peroxidase-like activity.

FeO nanoparticles (NPs) have emerged as pioneering nanozymes with applications in clinical diagnosis, environmental protection and biosensing. However, it is currently limited by insufficient catalytic activity due to poor electron transfer. In this study, we synthesized electron-rich-Zr-doped defect-rich FeO NPs (ZrFeO) using a one-pot solvothermal method.

Dual-Enhancement Electrochemiluminescence Device for Ultratrace Uranium Visualized Monitoring in Fish, Hair, and Nail Samples.

Uranium is a nuclear fuel but also a hazardous contaminant due to its radioactivity and chemical toxicity. To prevent and mitigate its potential threat, the accurate monitoring of ultratrace uranium (orders of magnitude of pg g) in practical environmental samples has become an important scientific problem. To meet this challenge, we developed an efficient electrochemiluminescence (ECL) UO detection device by a novel dual-enhancement mechanism.

Analysis of TLR10 gene polymorphisms in patients with rheumatoid arthritis.

Objective: Rheumatoid arthritis (RA) is a chronic systemic disease characterized by inflammatory synovitis, and genetic factors play the greatest role in RA. This study aimed to investigate the relationship between Toll-like receptor 10(TLR10) gene polymorphisms and susceptibility to RA.

Methods: A total of 271 patients with RA and an equal number of healthy controls were included, and the TLR10 rs2101521, rs10004195 and rs11725309 loci were genotyped by time-of-flight mass spectrometry.

Droplet Micro-Sensor and Detection of Respiratory Droplet Transmission.

Droplet transmission is the primary infection route for respiratory diseases like COVID-19 and influenza, but small and low-cost wearable droplet detection devices are a significant challenge. Herein, a respiratory droplet micro-sensor based on graphene oxide quantum dots (GOQDs) assembled onto SiO microspheres by the nebulized natural deposition is presented. Benefiting from the energy dissipation of the microsphere to droplets, the sensor can detect droplets as far as 2 m from coughing.

Transcriptomics to evaluate the influence mechanisms of ethanol on the ester production of Wickerhamomyces anomalus with the induction of lactic acid.

Wickerhamomyces anomalus is one of the most important ester-producing strains in Chinese baijiu brewing. Ethanol and lactic acid are the main metabolites produced during baijiu brewing, but their synergistic influence on the growth and ester production of W. anomalus is unclear.

Evaluation of the effect of Torulaspora delbrueckii on important volatile compounds in navel orange original brandy using E-nose combined with HS-SPME-GC-MS.

Simultaneous inoculation of non-Saccharomyces cerevisiae during the alcoholic fermentation process has been found to be an effective strategy for enhancing wine flavor. This study aimed to investigate the effect of Torulaspora delbrueckii NCUF305.2 on the flavor of navel orange original brandy (NOOB) using E-nose combined with HS-SPME-GC-MS.

Ether-Water Co-Solvent Electrolytes Enhanced Vanadium Oxide Cathode Cyclic Behaviors for Zinc Batteries.

Vanadium-based compounds are fantastic cathodes for aqueous zinc metal batteries due to the high specific capacity and excellent rate capability. Nevertheless, the practical application has been hampered by the dissolution of vanadium in traditional aqueous electrolytes owing to the strong polarity of water molecules. Herein, we propose a hybrid electrolyte made of Zn(ClO) salt in tetraethylene glycol dimethyl ether (G4) and HO solvents to upgrade the cycle life of Zn//KVO battery.

Differences in proximal and intimacy-related defense mechanisms among patients with cancer in different psychological stages of dying.

Purpose: This study measured three of the psychological stages of dying in patients with cancer and explored the differences in proximal and intimacy-related defense mechanisms at each stage.

Patients And Methods: A total of 220 cancer patients were recruited for this study; 168 patients met the inclusion criteria and were included in the data analysis. The participants were divided into three groups using the "Death Attitudes Questionnaire Revised" (1994) and then completed the Death-Thought Accessibility Test, Self-Control Questionnaire, Rumination Reflection Questionnaire, Attachment Type Test, Intimacy Test, External Control Test, and Positive and Negative Affect Scale.

Bibliometric analysis of childhood-onset systemic lupus erythematosus from 2000 to 2022.

Background: Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disorder. When SLE occurs in individuals under the age of 18, it is referred to as childhood-onset SLE (cSLE). Currently, there is a dearth of bibliometric research pertaining to cSLE.

Upper gastrointestinal tract microbiota with oral origin in relation to oesophageal squamous cell carcinoma.

Poor oral hygiene is linked to high risks of many systemic diseases, including cancers. Oral dysbiosis is closely associated with poor oral hygiene, causing tooth loss, gingivitis, and periodontitis. We provide a summary of studies and discuss the risk factors for oesophageal squamous cell carcinoma (ESCC) from a microbial perspective in this review.

Bibliometric analysis of global literature productivity in systemic lupus erythematosus from 2013 to 2022.

Background: Bibliometric analysis is a mature method for quantitative evaluation of academic productivity. In view of the rapid development of research in the field of systemic lupus erythematosus (SLE) in the past decade, we used bibliometric methods to comprehensively analyze the literature in the field of SLE from 2013 to 2022.

Methods: The relevant literature in the field of SLE from 2013 to 2022 was screened in the Web of Science Core Collection database.

Accuracy Analysis and Experimental Study of a Six-Dimensional Force Sensor with Circular Flexible Spherical Joints.

This paper proposed a circular flexible spherical joint to reduce the processing difficulty and manufacturing cost, and design a six-dimensional force sensor based on it. This paper analyzes the influence of the structural parameters of the flexible spherical joints on the accuracy of the six-dimensional force sensor by comparing the force mapping matrix of flexible spherical and ideal spherical joints. As the force mapping matrix is related to the stiffness matrix, the stiffness matrix of a six-dimensional force sensor based on a circular flexible spherical joint and the force mapping matrix of the generalized external force acting on the sensor was derived.

Porphyromonas gingivalis predicts local recurrence after endoscopic submucosal dissection of early esophageal squamous cell carcinoma or precancerous lesion.

Background: Porphyromonas gingivalis plays an oncogenic role in development and progression of esophageal squamous cell carcinoma (ESCC). However, the impact of P. gingivalis on local recurrence of early ESCC or precancerous lesion after ESD treatment remains unknown.

Bibliometric and altmetric analysis of research relating to antiphospholipid syndrome based on VOS viewer (2011-2021).

Background: Antiphospholipid syndrome is an autoimmune disorder characterized by recurrent vascular thrombosis and pregnancy losses in the presence of persistently positive antiphospholipid antibodies. Bibliometric analysis and altmetric analysis are methods of analyzing academic productivity and influence. Currently, the assessment of antiphospholipid syndrome through the above analyses is lacking.

Increase the Content of Ester Compounds in Blueberry Wine Fermentation with the Ester-Producing Yeast: , , and .

The co-fermentation of Saccharomyces cerevisiae and ester-producing yeasts is considered to be an effective way to improve the flavor and quality of fruit wine. In this study, three kinds of ester-producing yeasts (Candida glabrata NCUF308.1, Pichia anomala NCUF306.

Spatial and temporal dynamics of microbial community composition and factors influencing the surface water and sediments of urban rivers.

The temporal and spatial characteristics of urban river bacterial communities help us understand the feedback mechanism of bacteria to changes in the aquatic environment. The Fuhe River plays an important role in determining the water ecological environment of Baiyangdian Lake. 16S rRNA gene sequencing was used to study the microbial distribution characteristics in the Fuhe River in different seasons.